Clinical trials: Psychological Disorders
Stress, Anxiety
Cereset Research Long-Term Healthcare Worker Study
Randomized, controlled study of long-term maintenance Cereset Research after an initial 4-session intervention bolus versus usual care control following an initial 4-session intervention bolus.
- Conditions
- Stress, Anxiety, Autonomic Dysregulation, Acoustic Stimulation
- Trial name
- LT-HW (NCT05994261)
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Tobacco Use Disorder
Innovative Interventions for Smoking Cessation
The purpose of this study is to evaluate the effect of a combination of the 21 mg nicotine patch and very low nicotine content (VLNC) cigarettes compared to 21 mg nicotine patch only and very low nicotine content cigarette only…
- Trial name
- NCT01050569
- Testing
- Nicotine Patch, VLNC Cigarette, VLNC Cigarette Plus Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cocaine Related Disorders
The Effect of Yohimbine on Cocaine Cue Reactivity
Stress and cues reminiscent of cocaine use promote craving and relapse in cocaine dependent individuals. In addition, there appears to be gender differences in determinants of relapse to drug use following abstinence in…
- Trial name
- NCT00535002
- Testing
- Yohimbine
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Sleep, Insomnia
Treatment of Insomnia and Glucose Metabolism
Available data suggest that obtaining adequate sleep is associated with a better ability of the body to use carbohydrates as a source of energy and a lower risk of developing diabetes.
- Conditions
- Sleep, Insomnia, Insulin Resistance
- Trial name
- NCT00724282
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Alcohol Consumption, Alcohol Use Disorder
Step Away: Comparing a Chatbot-delivered Alcohol Intervention With a Smartphone App
A wide gap exists between the number of people needing alcohol treatment and those actually receiving it. This study builds on a previous one that indicated that smartphone-based intervention can help increase the number of…
- Trial name
- NCT04447794
- Testing
- Step Away Chatbot, Step Away App
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- University of Alaska Anchorage
Posttraumatic Stress Disorder
Nepicastat for Posttraumatic Stress Disorder (PTSD) in OIF/OEF Veterans
This study proposes a multi-site, randomized, double-blind, placebo-controlled clinical trial of the dopamine-ß-hydroxylase (DBH) inhibitor, nepicastat, for the treatment of posttraumatic stress disorder (PTSD) in outpatients who…
- Trial name
- Nepicastat (NCT00659230)
- Testing
- Nepicastat
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tuscaloosa Research & Education Advancement Corporation
Development Delay, Neurodevelopmental Disorders
Translating Peer-to-Peer Support Into a Clinical Setting
There is not a lot of research focusing on Black and African American families raising young children with developmental delays.
- Conditions
- Development Delay, Neurodevelopmental Disorders, Autism
- Trial name
- NCT04313283
- Testing
- Parents Taking Action
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Major Depressive Disorder
Riluzole Augmentation Pilot in Depression (RAPID) Trial
The investigators are doing a research study to find out if riluzole, when taken along with a standard antidepressant (sertraline) can help people with major depression.
- Trial name
- RAPID (NCT01703039)
- Testing
- Riluzole, Sertraline
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Tobacco Dependence
Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction
Smokeless tobacco (ST) is a known human carcinogen. Long-term ST use is known to increase the risk for oropharyngeal cancer. Extant literature on cigarette smokers suggests that smoking reduction increases smoking abstinence…
- Trial name
- NCT01018394
- Testing
- nicotine lozenges, tobacco-free snuff
- Where
- 2 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Alzheimer Disease, Alzheimer Disease (AD)
Phase I Clinical Study of AV-1959R: Abeta-targeting Anti-Alzheimer's Vaccine
This Phase 1 clinical trial evaluates the safety, tolerability, and immune response of the adjuvanted AV-1959R vaccine in healthy adults aged 40-60.
- Conditions
- Alzheimer Disease, Alzheimer Disease (AD), Alzheimers Disease Prevention
- Trial name
- NCT06831812
- Testing
- AV-1959R (Abeta vaccine)
- Where
- Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Nuravax, Inc.
Substance Use Disorders
Cognitive Stimulation
This research is being done to learn if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking.
- Trial name
- NCT01271413
- Testing
- Computerized cognitively stimulating activities
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tobacco Use Disorder
Working Memory Training Combined With Transcranial Magnetic Stimulation in Smokers
Smoking remains the leading cause of preventable death in the United States, and current first-line treatments leave the majority of tobacco dependent individuals unable to quit.
- Trial name
- NCT03337113
- Testing
- Working Memory Training, repetitive Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kent State University
Alcohol Dependence, PTSD
Neuromodulation of Trauma Memories in PTSD & Alcohol Dependence
The purpose of this study is to examine the effect of propranolol versus placebo on craving, distress and cue reactivity to trauma and alcohol cues.
- Trial name
- NCT01055171
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Use Disorder
The Effects of Sedatives on Tobacco Use Disorder
This proposal will obtain preliminary data on the effect of a single sub-anesthetic dose of a sedative on cigarette craving and smoking behavior as well as measuring tolerability and acceptability.
- Trial name
- SED-TUD (NCT03813121)
- Testing
- midazolam intravenous infusion, ketamine intravenous infusion
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Attention-Deficit/Hyperactivity Disorder
Open-label Safety and Efficacy of SPN-812 (Viloxazine Extended-release Capsule) in Adults With ADHD and Mood Symptoms
Open label, flexible dose, decentralized clinical trial evaluating the efficacy and safety of SPN-812 in adults with ADHD and mood symptoms.
- Trial name
- NCT06185985
- Testing
- SPN-812
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Supernus Pharmaceuticals, Inc.
Mental Disorders
A Randomized Controlled Trial of Mental Health Peer-Led Education
This randomized controlled trial tests the efficacy of a mental health peer-led educational intervention called BRIDGES (Building Recovery of Individual Dreams and Goals through Education and Support).
- Trial name
- BRIDGES (NCT01297985)
- Testing
- BRIDGES Peer-Led Education
- Where
- United States
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Nicotine Dependence, E-Cig Use
Research and Innovation to Stop E-cigarette/Vaping in Young Adults
The aim of this study is to test intervention components to help young adults quit vaping. A 2x2 factorial design will be used where all participants receive quitline-delivered behavioral phone counseling, and components to be…
- Trial name
- (RISE) (NCT04974580)
- Testing
- Nicotine patch, Phone Counseling, Digital Coaching
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Depression, Substance-Related Disorders
Middle School to High School Transition Project: Depression and Substance Abuse Prevention
This study will implement a school-based program to prevent depression, academic failure, and substance use in at-risk adolescents transitioning from middle school to high school.
- Trial name
- CAST-T/HSTS (NCT00071513)
- Testing
- CAST-T/HSTS, Brief Intervention
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of Washington
Substance Abuse
Preventing Drug Abuse Among Sexual Minority Youth
The planned randomized clinical trial will longitudinally test a tailored, web-based drug abuse prevention program with a nationwide sample of 15- to 17-year-old sexual minority youth (youth who identify as gay, lesbian…
- Trial name
- NCT03954535
- Testing
- Free2b
- Where
- United States
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Columbia University
Schizophrenia
A Pharmacokinetic Study of Lurasidone After Single Oral Administration in Healthy Subjects
To evaluate the pharmacokinetic (PK) characteristics of lurasidone after single oral administration of different doses in healthy Chinese subjects.
- Trial name
- NCT02174510
- Testing
- 20mg lurasidone, 40mg lurasidone, 80mg lurasidone
- Where
- China
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Marubeni Pharmaceuticals (Suzhou) Co., Ltd.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.