Clinical trials: Psychological Well-being
Major Depressive Disorder
VA Augmentation and Switching Treatments for Improving Depression Outcomes
The overall purpose is to determine research based 'next-steps' for outpatients with major depressive disorder who have not had satisfactory outcomes to standard 'first-step' treatments.
- Trial name
- VAST-D (NCT01421342)
- Testing
- Switching: Bupropion-SR, Augmenting: Antidepressant + Bupropion-SR, Augmenting: Antidepressant + Aripiprazole
- Where
- 35 sites in United States
- Volunteers
- 1,522 people
- Sponsor
- VA Office of Research and Development
Anorexia Nervosa, Eating Disorder
Hormonal Factors in the Treatment of Anorexia Nervosa
The investigators are investigating whether a hormone that is naturally produced by the human body, called testosterone, can help improve weight, disordered eating, depression, and anxiety.
- Conditions
- Anorexia Nervosa, Eating Disorder, Anxiety, Depression
- Trial name
- NCT01121211
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Massachusetts General Hospital
Caregiver Burnout
Volunteering Program for Chinese Dementia Caregivers
Although many older Chinese Americans are expected to need intensive care because of cognitive impairment, a large gap exists in development of culturally sensitive interventions to reduce stress among caregivers in Chinese…
- Trial name
- NCT04346745
- Testing
- Peer Mentoring Program
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Stress, Psychological
The Impact of 8 Weeks of Digital Meditation Application and Healthy Eating Program on Work Stress and Health Outcomes
The aim of the present study is to test the effects of a digital meditation intervention and/or a healthy eating intervention in a sample of UCSF employees with overweight and obesity (BMI>=25kg/m2) who report mild to moderate…
- Conditions
- Stress, Psychological, Behavioral Symptoms, Sleep
- Trial name
- SFUC+Health (NCT03945214)
- Testing
- Meditation, Healthy Eating, Meditation + healthy eating
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes, Depression
HOPE Pilot for Veterans With Complex Diabetes
The purpose of this study is to determine if behavioral health coaching for rural veterans with diabetes and depression will improve self-management behaviors and lead to improvement in diabetes care outcomes (e.g., HA1C) and…
- Trial name
- HOPE (NCT01274715)
- Testing
- Behavioral Health Coaching
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Human Immunodeficiency Virus, Mental Health
Digital Star: HIV Prevention for Youth in Mental Health Treatment
Teenagers in mental health treatment are at greater risk for HIV and other sexually transmitted infections. This greater risk comes from many factors, some of which are related to poor emotion regulation and low self-confidence.
- Trial name
- DSTAR (NCT02921841)
- Testing
- D*STAR, D*HEALTH
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Rhode Island Hospital
Suicide, Nurse's Role
Nurse Suicide: Physiologic Sleep Health Promotion Trial
The purpose of this study is to identify factors (sleep, psychiatric characteristics, stressful life events, and work environment characteristics) that potentiate or mitigate adverse effects of real-world stressors that…
- Conditions
- Suicide, Nurse's Role, Work Environment Adverse Effects, Sleep
- Trial name
- NCT06079853
- Testing
- PureSomni Sleep Health Product Kit
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Columbia University
Massage Therapy, Health-care Workers
Can Massage During One Year Improve Health in Health-care Providers Working in Hospital
The overall aim of this pilot study is to investigate the effect, "feasibility" and experiences of regular massage over 12 months on the mental and physical health of healthcare professionals, as well as the frequency of layoffs…
- Conditions
- Massage Therapy, Health-care Workers, Quality of Life, Psychological Distress
- Trial name
- NCT05555082
- Testing
- Massage
- Where
- 2 sites in Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Sleep Apnea, Obstructive, Patient Compliance
Tailored Intervention to Promote Positive Airway Pressure Adherence
The purpose of this study is to examine the feasibility of a tailored (i.e., individualized) intervention to promote adherence to continuous positive airway pressure therapy (CPAP) in adults with newly-diagnosed, CPAP treated…
- Trial name
- SCIP-PA (NCT01454830)
- Testing
- Tailored, Usual care
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Milton S. Hershey Medical Center
Child Behavior Disorders
Safer Use of Antipsychotics in Youth
This study tests the effectiveness of an intervention treatment algorithm vs. usual care control in a practical clinical trial. Control arm providers will receive a standard medication alert in the electronic medical record (EMR)…
- Trial name
- SUAY (NCT03448575)
- Testing
- Control - Provider Medication Alert Only, Intervention - Alert + CAP Review AND Enhanced BH Access
- Where
- 4 sites in United States
- Volunteers
- 733 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Dementia, Alzheimer Disease
Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers
The goal of this clinical trial is to evaluate Kinto's Care Coaching intervention for dementia caregivers. The main questions it aims to answer are: Does the intervention help caregivers to address their general caregiving goals…
- Conditions
- Dementia, Alzheimer Disease, Lewy Body Disease, Vascular Dementia
- Trial name
- NCT05916664
- Testing
- Kinto Care Coaching
- Where
- United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Kinto
Generalized Anxiety Disorder
Exercise Training for the Treatment of Generalized Anxiety Disorder
The purpose of this study is to compare the effects of 6 weeks of endurance or strength training and a wait list comparison condition on symptoms of Generalized Anxiety Disorder (GAD).
- Trial name
- NCT00953654
- Testing
- Strength Training, Endurance Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Georgia
Physical Violence, Educational Achievement
Good Schools Study
The purpose of this study is to determine whether use of the Good Schools Toolkit is effective in reducing violence against children in primary schools.
- Conditions
- Physical Violence, Educational Achievement, Mental Health, Sexual Violence
- Trial name
- GSS (NCT01678846)
- Testing
- Good School Toolkit
- Where
- Uganda
- Volunteers
- 3,820 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Critical Illness
Improving Outcomes After PICU Admission: A Pilot Study
1. Evaluate the feasibility and acceptability of an information based intervention delivered to parents following their child's admission to paediatric intensive care; 2.
- Trial name
- NCT01737021
- Testing
- Psycho-education
- Volunteers
- 31 people
- Sponsor
- Imperial College London
Major Depressive Disorder
Therapist-Guided Smartphone-Delivered CBT for MDD
We are testing a smartphone app that provides therapy for depression. Participants will also receive short weekly virtual appointments with a therapist.
- Trial name
- NCT05386329
- Testing
- Mindset: Therapist-guided smartphone-delivered CBT
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Massachusetts General Hospital
Anxiety, Depression
COVID-19 and the Healthy Minds Program for Educators
This study is a randomized controlled trial (RCT) of the four-week Healthy Minds Program (HMP) app Foundations training in employees of a mid-size urban school district in the United States during the summer of 2020, in the midst…
- Conditions
- Anxiety, Depression, Psychological Stress, Psychological Distress
- Trial name
- CAHMP-ED (NCT04426318)
- Testing
- Healthy Minds Program Foundations Training
- Where
- United States
- Volunteers
- 698 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy
Mental and Physical Well-Being of Frontline Health Care Workers During Coronavirus Disease 2019 (COVID-19)
Study to support the mental and physical well-being of US health care workers during the COVID-19 pandemic and ensure high-quality care for patients through Stress First Aid.
- Trial name
- COVER-HCW (NCT04723576)
- Testing
- Stress First Aid
- Where
- 2 sites in United States
- Volunteers
- 7,444 people, healthy volunteers welcome
- Sponsor
- RAND
Alzheimer Disease, Mild Memory Disturbance
The MObile AssessMENT of Behavioral and Psychological Symptoms of Dementia in Amnestic MCI and AD (MOMENT) Study
The purpose of this research study is to learn whether it is possible and useful for caregivers to report behavioral or psychological symptoms of people with mild memory problems or Alzheimer's disease through a smartphone mobile…
- Conditions
- Alzheimer Disease, Mild Memory Disturbance, Mild Cognitive Impairment
- Trial name
- MOMENT (NCT04482036)
- Testing
- Mobile Phone Application Assessments, Standard Assessments
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cancer Pain, Opioid Use
Psychological Intervention Using Smartphone Technology to Alleviate Malignant Pain
The purpose of this study is to develop and pilot test a novel medical intervention (STAMP+CBT app) that will help patients track their pain, mood, opioid use and side effects while delivering tailored education and…
- Conditions
- Cancer Pain, Opioid Use, Cognitive Behavior Therapy
- Trial name
- STAMP+CBT (NCT05774197)
- Testing
- Cognitive Behavioral Therapy for pain
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Oklahoma