Clinical trials: Psychological and Behavioral Symptoms
Generalized Anxiety, Introspective & Anxiety-Prone Patient
Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study.
In France today, it is estimated that one in every 850 people aged between 20 and 45 is a childhood cancer survivor (CCS), equivalent to around 40,000 to 50,000 people.
- Conditions
- Generalized Anxiety, Introspective & Anxiety-Prone Patient, Depression, Anxiety, Survivors of Childhood Cancer
- Trial name
- HARMONY-Tool (NCT07117058)
- Testing
- New rapid screening tool for anxiety and depressive disorders, SCARED-R-51 (Screen for Child Anxiety Related Emotional Disorders-Revised), HADS (Hospital Anxiety and Depression Scale)
- Where
- 7 sites in France
- Volunteers
- 545 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Financial Toxicity
A Longitudinal Study of the Trajectory of Financial Toxicity and Its Relationship With Symptom Burden in Breast Cancer Patients
Breast cancer has become the leading cause of global cancer incidence. With the improvement of treatment methods, some breast cancer patients have experienced different degrees of financial toxicity, which seriously affected the…
- Trial name
- NCT05964816
- Where
- 4 sites in China
- Volunteers
- 485 people
- Sponsor
- Fudan University
Recovery, Psychological, Sleep
Leadership for Recovery: Evaluation of an Intervention Programme for First-line Healthcare Managers
The goal of this intervention study is to evaluate a group intervention programme that aims to support first-line healthcare managers in promoting their employees' recovery through a "leadership for recovery".
- Conditions
- Recovery, Psychological, Sleep, Burnout, Work Related Stress
- Trial name
- NCT06678347
- Testing
- Leadership for recovery
- Where
- 2 sites in Sweden
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Breech Presentation, External Cephalic Version
EBIS: The Eindhoven Breech Intervention Study
The purpose of this study is to evaluate whether successful external cephalic version is associated with maternal thyroid function and mood state in pregnant women with breech presentation at term.
- Conditions
- Breech Presentation, External Cephalic Version, Thyroid Hormones, Stress, Psychological
- Trial name
- NCT00516555
- Where
- Netherlands
- Volunteers
- 250 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Neurological and Mental Health Conditions, Genetic Susceptibility
Mapping Antenatal Maternal Stress - Child Outcomes
This study is a sub-study of Mapping Antenatal Maternal Stress (MAMS). Women previously enrolled in MAMS, their children and their partners/spouses were recruited for a set of more comprehensive assessments to characterise early…
- Conditions
- Neurological and Mental Health Conditions, Genetic Susceptibility, Socioeconomic Factors, Psychology, Social
- Trial name
- MAMS-CO (NCT07432243)
- Where
- Singapore
- Volunteers
- 587 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Schizophrenia, Psychological Trauma
Cognitive Behaviour Therapy for Voices and Dissociation
Case series design with participants with psychosis with a history of interpersonal trauma/abuse and current distressing auditory verbal hallucinations and dissociative experience.
- Conditions
- Schizophrenia, Psychological Trauma, Dissociation, Hallucinations
- Trial name
- NCT04990414
- Testing
- Cognitive Behavioural Therapy
- Volunteers
- 19 people
- Sponsor
- Greater Manchester Mental Health NHS Foundation Trust
Health Behavior, Noncommunicable Diseases
The LvL UP Trial: Assessing the Effectiveness of a mHealth Intervention
Non-communicable diseases (NCDs), such as cardiovascular disease, diabetes, or cancer, and common mental disorders (CMDs), such as depression or anxiety, represent the primary causes of death and disability worldwide, causing…
- Conditions
- Health Behavior, Noncommunicable Diseases, Mental Health Issue, Lifestyle Risk Reduction
- Trial name
- NCT06592443
- Testing
- LvL UP, LvL UP + MI, Comparison
- Where
- 2 sites in Singapore
- Volunteers
- 1,061 people, healthy volunteers welcome
- Sponsor
- Singapore ETH Centre
Breast Cancer Female, Chemotherapy Effect
Quality of Life Improvement During Chemotherapy
This study is a randomized controlled trial, taking place at the University Hospital Basel (CH). It aims at the alleviation of breast cancer patients' life quality during chemotherapy.
- Trial name
- QoLMa (NCT04694885)
- Testing
- Structured Hypnotherapy
- Where
- Switzerland
- Volunteers
- 62 people
- Sponsor
- University Hospital, Basel, Switzerland
Burnout, Secondary Traumatic Stress
Burnout, Secondary Traumatic Stress and Inflammatory Biomarkers in ICU Healthcare Workers
Healthcare professionals working in intensive care units (ICUs) are frequently exposed to high levels of psychological stress due to critically ill patients, frequent encounters with death, complex clinical decision-making, and…
- Conditions
- Burnout, Secondary Traumatic Stress, Occupational Stress, Inflammation
- Trial name
- NCT07437443
- Testing
- Psychometric Assessment and Blood Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Interpersonal Psychotherapy, Family Caregivers
Application of Group Interpersonal Psychotherapy (IPT-G) to Family Members Caring for Patients With Schizophrenia
The goal of this re-measured quasi-experimental study is to evaluate the effect of Group Interpersonal Psychotherapy (IPT-G) intervention given to caregiver family members of people with schizophrenia on caregiver burden…
- Trial name
- IPT-G (NCT05870384)
- Testing
- Group Interpersonal Psychotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Cleft Lip and Cleft Palate
The Financial and Emotional Impact of Cleft Palate
Cleft lip and/or palate (CL±P) is the most prevalent congenital craniofacial defect with a significant social impact, affecting speech, hearing, feeding, oral behavior, dentition and satisfaction with appearance.
- Trial name
- NCT06905678
- Testing
- Questionnaires, Semi-structured interviews
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- University Hospital, Ghent
Stress, Professional, Resilience
Resilience and Acute Stress in Simulation
The objective is to study an association between the resilience developed by anesthesia professionals and the level of acute stress during a simulation session.
- Conditions
- Stress, Professional, Resilience, Anaesthesiology, Simulation
- Trial name
- SimStress (NCT05353621)
- Testing
- VAS reported Stress
- Where
- France
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Depression
Beyond Efficacy- Eliciting Preference for Face-to-face and Internet-based Psychotherapy Among People with Depression
The aim of this study is to strengthen the evidence base of clients' preferences of psychotherapy and to close the described literature gaps so as to inform public health resource reallocation and implementation of psychological…
- Trial name
- NCT05449561
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Domestic Violence, Depression
Cortisol Evaluation in Abuse Survivors
This study looks at the biological effect of domestic violence and abuse (DVA) on women's mental health. The mechanisms through which DVA causes mental disorders are very poorly understood.
- Conditions
- Domestic Violence, Depression, Anxiety, Panic Disorder
- Trial name
- CEASE (NCT01632553)
- Where
- 2 sites in United Kingdom
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Pregnancy Complications, Mental Health Issue
Psychobiological Interventions in Pregnancy
This randomized control trial will evaluate whether a physical activity intervention can improve mental health and biologic markers of stress in pregnant people with depressive or anxiety symptoms.
- Conditions
- Pregnancy Complications, Mental Health Issue, Depression, Anxiety, Pregnancy, High Risk
- Trial name
- PIP (NCT06430853)
- Testing
- Step count goal, Actigraph watch
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Stanford University
Treatment-resistant Depression (TRD)
Esketamine With or Without Integration Therapy for Treatment-Resistant Depression
This study will explore the effects of esketamine (Spravato®), an FDA-approved nasal spray, on adults diagnosed with treatment-resistant depression (TRD).
- Trial name
- KIND-PR (NCT07369102)
- Testing
- Esketamine hydrochloride (intranasal), Integration Therapy
- Where
- 2 sites in Puerto Rico
- Volunteers
- 20 people
- Sponsor
- University of Puerto Rico
Caregiver Burden, Family Characteristics
Youth Mental Health Recovery in the Family After Inpatient Stay
The goal of this longitudinal mixed-methods study is to investigate caregiver strain, family processes and health outcomes after youth psychiatric inpatient treatment.
- Conditions
- Caregiver Burden, Family Characteristics, Parent-Child Interactions
- Trial name
- ReCoVer (NCT06865573)
- Volunteers
- 70 people
- Sponsor
- University of Vienna
Musculoskeletal Pain, Cognitive Change
Health, Wellbeing and Performance in Law Enforcement Workers
This study aims to assess current health and fitness of law enforcement workers in various roles, and to evaluate the impact of an exercise intervention on markers on physical and mental wellbeing in this population.
- Conditions
- Musculoskeletal Pain, Cognitive Change, Occupational Stress, Inflammation
- Trial name
- NCT04204486
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University College, London
Obesity, Childhood
Wise Social Psychological Interventions to Improve Outcomes of Behavioral Weight Control in Children With Obesity
A 2-arm, parallel group, randomized controlled trial to evaluate overall differences in body mass index (BMI) trajectories over 6 months between 10-16-year-old children with obesity randomized to receive the wise social…
- Trial name
- NCT04422951
- Testing
- Wise interventions -- values self-affirmation and growth mindset -- plus usual care behavioral treatment, Education plus usual care behavioral treatment
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Stanford University
Burnout, Professional, Intensive Care
National French Survey on Psychological Distress at Work of Anesthesia and Intensive Care Residents
Psychological distress is a significant problem for healthcare professionals and students in training. The investigator question the prevalence of this problem in French residents in anaesthesia and intensive care training.
- Conditions
- Burnout, Professional, Intensive Care, Anesthesia, Depression, Anxiety
- Trial name
- PSY-DESAR (NCT04350151)
- Testing
- no intervention
- Where
- France
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Facteurs Humains en Santé
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