Clinical trials: Psychomotor Agitation
Lumbar Disc Herniation, Emergence Agitation
Magnesium Sulfate for Prevention of Emergence Agitation in Lumbar Disc Surgery
In this retrospective study, the effect of intraoperative magnesium sulfate infusion on the incidence of postoperative emergence agitation was evaluated in adult patients who underwent elective lumbar microdiscectomy under…
- Conditions
- Lumbar Disc Herniation, Emergence Agitation, Magnesium Sulfate
- Trial name
- NCT07139847
- Testing
- Magnesium Sulfate Infusion, 0.9% Saline Infusion
- Volunteers
- 70 people
- Sponsor
- Ondokuz Mayıs University
Agitation in Patients With Dementia of the Alzheimer's Type, Alzheimer Disease
Assessing Clinical Outcomes in Alzheimer's Disease Agitation
This is a multi-center, double-blind, placebo-controlled, randomized withdrawal study to evaluate the efficacy and safety of AXS-05 compared to placebo in the treatment of agitation symptoms in subjects with agitation associated…
- Conditions
- Agitation in Patients With Dementia of the Alzheimer's Type, Alzheimer Disease, Agitation,Psychomotor
- Trial name
- ACCORD (NCT04797715)
- Testing
- AXS-05
- Where
- 63 sites in United States, Canada
- Volunteers
- 178 people
- Sponsor
- Axsome Therapeutics, Inc.
Agitation Associated With, Alzheimer's Disease
Safety and Tolerability Study of Flexible Dosing of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type
To compare the efficacy of flexible dosing of brexpiprazole with placebo in subjects with agitation associated with dementia of the Alzheimer's type
- Conditions
- Agitation Associated With, Alzheimer's Disease, Alzheimer's Type, Mental Disorder
- Trial name
- NCT01922258
- Testing
- Brexpiprazole, OPC-34712
- Where
- 70 sites in United States, Bulgaria and 7 more
- Volunteers
- 270 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Dementia
The Effects of White Noise on Agitated Behaviors and Cortisol Level in Saliva Among the Patients With Dementia
The purpose of this study will be to examine the effects of white noise on agitation and saliva cortisol in elderly with dementia.
- Trial name
- NCT02271321
- Testing
- White noise
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- Chang Bing Show Chwan Memorial Hospital
Alzheimer Disease, Agitation in Dementia
Human Mesenchymal Stem Cells (hMSC) in Behavioral Problems Due to Alzheimer's Disease.
The purpose of this research study is to test if adding one infusion of mesenchymal stem cells to the current treatment with antipsychotic medication may help control behavioral problems in people with a diagnosis of moderate to…
- Trial name
- NCT06781333
- Testing
- hMSC
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Bernard (Barry) Baumel
Agitation
Nalbuphine Versus Dexmedetomidine for Prevention of Emergence Agitation in Pediatrics
the investigators hypothesized that Nalbuphine may be alternative pharmacological agent for prevention of emergence agitation in pediatrics who will be scheduled for elective lower abdominal surgical procedures (inguinal hernia…
- Trial name
- NCT05273671
- Testing
- Nalbuphine, Dexmedetomidine, normal Saline
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Alexandria University
Emergence Agitation
A Comparison of Emergence Agitation by Sevoflurane for Intraoperative Sedation Associated With Caudal Block
This study was performed to compare the incidence of EA between two dose of sevoflurane for sedation with caudal block in children, and intended to find the optimal dose for prevention of sevoflurane induced emergence agitation
- Trial name
- NCT03134547
- Testing
- low dose sevoflurane group, high dose sevoflurane group
- Volunteers
- 40 people
- Sponsor
- Yeungnam University College of Medicine
Sublingual, Caffeine
Sublingual Caffeine on Reducing Recovery Time and Postoperative Agitation in Elderly Patients Undergoing General Anesthesia
This study aims to evaluate the efficacy of sublingual caffeine in reducing recovery time and incidence of postoperative agitation in elderly patients undergoing general anesthesia.
- Conditions
- Sublingual, Caffeine, Recovery Time, Postoperative Agitation
- Trial name
- NCT07536568
- Testing
- Caffine citrate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Nasal Surgery
Performance of EEG During Emergence Agitation in Nasal Surgery.
The purpose of the study is to evaluate the relationship between perioperative electroencephalogram and emergence agitation in the nasal surgery.
- Trial name
- NCT05654311
- Testing
- Nasal surgery
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Gangnam Severance Hospital
Agitation,Psychomotor, Haloperidol Causing Adverse Effects in Therapeutic Use
Inhaled Loxapine vs Intramuscular (IM) Haloperidol + Lorazepam for Agitation
The primary objective of this study is to determine the noninferiority of inhaled loxapine compared to intramuscular haloperidol/lorazepam on agitation reduction at 120 minutes.
- Conditions
- Agitation,Psychomotor, Haloperidol Causing Adverse Effects in Therapeutic Use, Lorazepam Causing Adverse Effects in Therapeutic Use, Loxapine Causing Adverse Effects in Therapeutic Use
- Trial name
- loxapine (NCT03110900)
- Testing
- Haloperidol + lorazepam, Loxapine
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Neuromuscular Blockade, Delayed Emergence From Anesthesia
Sugammadex Timing and Recovery Profile in Pediatric Adenotonsillectomy
Sugammadex is routinely used to reverse rocuronium-induced neuromuscular blockade in children. In clinical practice, it is given either while the child is still deeply anesthetized or after the anesthetic has lightened.
- Conditions
- Neuromuscular Blockade, Delayed Emergence From Anesthesia, Emergence Agitation
- Trial name
- SUGA-PED (NCT07902193)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Namik Kemal University
Entropion
The Effect of Preoperative Ketamine on the Emergence Characteristics in Children Undergoing Entropion Surgery
The investigators evaluate extubation time and recovery profiles in children undergoing entropion surgery.
- Trial name
- NCT02916407
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Inje University
Akathisia, Nausea
Efficacy and Akathisia Incidence of Slow Infusion Metoclopramide
Study Objective: The purpose of this study is to compare the effects of metoclopramide administration in bolus versus slow infusion medications in ED patients complaining of nausea for the determination of the therapeutic effect…
- Trial name
- NCT01069536
- Testing
- metoclopramide 10 mg
- Volunteers
- 140 people
- Sponsor
- Pamukkale University
Emergence Agitation
Effect of Induction Method in Post Operative Agitation
To compare the effect of two different induction method; mask ventilation and intravenous cannulation on emergence agitation on pediatric adenotonsillectomy
- Trial name
- NCT03252405
- Testing
- mask ventilation, intravenous cannulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Ahi Evran University Education and Research Hospital
Alzheimer Disease, Psychosis
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
The purpose of this study is to evaluate KarXT + KarX-EC as a treatment for psychosis associated with Alzheimer's disease.
- Trial name
- NCT06947941
- Testing
- KarXT, KarX-EC
- Where
- 22 sites in United States, Australia and 3 more
- Volunteers
- 325 people
- Sponsor
- Bristol-Myers Squibb
FOXP1 Syndrome
Psychiatric Phenotype Characterization of Individuals With FOXP1 Syndrome
FOXP1 syndrome is a rare genetic disorder with a variable phenotype, characterized somatically by facial dysmorphia, dysphagia, hypotonia, relative or real macrocephaly, which may be associated with cerebral, cardiac, urogenital…
- Trial name
- FOXP1-PP (NCT06211673)
- Testing
- Semi-structured interviews, Heteroquestionnaires
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Emergence Delirium, Emergence Agitation
Postoperative Neurocognitive Dysfunction: Is There Any Place for Emergency Agitation: A Prospective Cohort Trial
Perioperative neurocognitive disorders (PND) have been studying by clinicians, particularly by anesthesiologists, pretty long, however the most inspiring advancements were achieved during the last few decades.
- Conditions
- Emergence Delirium, Emergence Agitation, Postoperative Delirium
- Trial name
- PoD (NCT04820595)
- Testing
- RASS, CAM-ICU
- Where
- 2 sites in Russia
- Volunteers
- 200 people
- Sponsor
- Negovsky Reanimatology Research Institute
Psychomotor Agitation
Haloperidol vs. Valproate in Agitation
The aim of this study is to compare the efficacy of haloperidol and valproate in management of people with agitation in emergency department
- Trial name
- NCT01750541
- Testing
- Haloperidol, Valproate
- Where
- Iran
- Volunteers
- 56 people
- Sponsor
- Shahid Beheshti University of Medical Sciences