Clinical trials: Psychosis Nos/Other
Schizophrenia and Related Disorders, Mental Competency
DEcision-making Capacity: Intervention Development & Evaluation in Schizophrenia-spectrum Disorder
Treatment decision-making capacity ('capacity') refers to a person's ability to make decisions about their treatment. It is an important issue for people diagnosed with a schizophrenia-spectrum disorder ('psychosis') because…
- Trial name
- DEC:IDES (NCT04309435)
- Testing
- Self-esteem intervention, Self-stigma intervention, Jumping to conclusions intervention
- Where
- 3 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Edinburgh Napier University
Parkinson's Disease, Psychoses
Aripiprazole in Patients With Psychosis Associated With Parkinson's Disease
The purpose of this clinical research study is to assess the safety and tolerability of aripiprazole in patients with psychosis associated with Parkinson's disease.
- Trial name
- NCT00095810
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Schizoaffective Disorders, Bipolar Disorder With Psychotic Features
Transition Care for FEP
This study is testing a new approach to help people with first episode psychosis transition successfully from the hospital to outpatient mental health care.
- Conditions
- Schizoaffective Disorders, Bipolar Disorder With Psychotic Features, Schizophrenia Disorders, Major Depressive Disorder With Psychotic Features
- Trial name
- TCT FEP (NCT07713849)
- Testing
- Transition Care Team
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Chicago
Psychosis Nos/Other
A Treatment Engagement Protocol for Psychiatrically Hospitalized Adolescents at Clinical High Risk for Psychosis
The current study explores the development and use of a family engagement intervention for psychiatrically hospitalized adolescents with emerging psychosis symptoms.
- Trial name
- NCT04314635
- Testing
- Brief family engagement intervention for CHR, Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rhode Island Hospital
Psychosis
Effectiveness of the Combination of Water Aerobics and Metacognitive Training
The objective of this study is to assess the efficacy of a combined intervention of water aerobics and Metacognitive Training (MCT), compared to each intervention separately, in people with psychosis.
- Trial name
- NCT05455593
- Testing
- Water aerobics, Metacognitive Training (MCT), Combined intervention
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundació Sant Joan de Déu
Schizophrenia
The Effects of Prebiotics on Cognitive Functioning and Weight Gain in Psychosis
The investigators propose a maltodextrin-controlled cross over experimental medicine study that aims to examine the role of the immune system in cognitive processes and weight gain in 40 adult patients with psychosis, stable on…
- Trial name
- Prepsy (NCT03153046)
- Testing
- prebiotics, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- University of Oxford
Prodromal Schizophrenia
Evaluation of Step-Based Care for Individuals at Clinical High Risk for Psychosis
The Ohio State University Early Psychosis Intervention Center is implementing a specialized clinical program to serve individuals who meet clinical high risk criteria for a psychosis.
- Trial name
- NCT03970005
- Testing
- Step-Based Care Model
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Device Adherence
Effectiveness of a Digital Platform in Engagement and Prognosis of Patients in an Early Intervention Pychosis Programme
This is a randomised, prospective, controlled trial in which one group (experimental group; GE) receives access to the PIPPEP (Intervention Programme for Early Psychosis) platform in addition to the treatment as usual (TAU) in…
- Trial name
- NCT06556251
- Testing
- PIPPEP App
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Fundació Sant Joan de Déu
Psychotic Disorders
Effects of a Peer-facilitated, Recovery-focused Self-illness Management Program for First-episode Psychosis
Psychosis is a major disabling and disruptive mental illness characterized by a wide variety of disturbances in cognition and emotions, resulting in poor psychosocial functioning and frequent relapses.
- Trial name
- Peer-RESIM (NCT06487195)
- Testing
- Peer-facilitated, Recovery-based Self-illness-management programme, Psycho-education group, Treatment-as-usual only
- Where
- Hong Kong
- Volunteers
- 198 people
- Sponsor
- Chinese University of Hong Kong
Schizophrenia, Psychotic Disorders
Dimensional and Developmental Profiles of Psychosis in Children and Adolescents
Five collaborating sites in France will study the broad spectrum of schizophrenia in children and adolescents. Patients will be studied with diagnostic interviews, developmental histories, dimensional clinical ratings…
- Trial name
- PSYDEV (NCT04370730)
- Testing
- clinical, neuroimaging and DNA assessments
- Where
- 6 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Psycho-social Support on Mental Health and Hope of Adolescents Affected by Earthquake in Nepal
Adolescents are prone to mental health problems such as post-traumatic stress disorder (PTSD) and depression which could become worse in the aftermath of disasters.
- Trial name
- NCT03387007
- Testing
- Psychosocial support training for school teachers
- Volunteers
- 1,912 people, healthy volunteers welcome
- Sponsor
- Tokyo University
Schizophrenia, Schizoaffective Disorder
Targeting Cerebellum to Treat Psychosis: a Transcranial Magnetic Stimulation (TMS) Study
The goal of this study is to use transcranial magnetic stimulation (TMS) to investigate the impact of modulating cerebellar activity on time perception, executive function, and mood and psychotic symptoms in psychosis patients…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder I
- Trial name
- NCT02642029
- Testing
- Excitatory TMS, Inhibitory TMS
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Psychosis
Online Yoga and the Impact on Psychosis
Yoga and mindfulness are considered complementary and alternative healthcare options that involve breathing techniques, relaxation, and bodily postures (yoga only).
- Trial name
- NCT05046912
- Testing
- Yoga, Mindfulness
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Royal Ottawa Mental Health Centre
Psychotic Disorders, Psychiatric Hospitalization
Youth Experiences and Health Study
This study aims to identify unusual experiences and psychiatric symptoms that indicate a heightened risk for severe mental disorders - especially psychoses.
- Conditions
- Psychotic Disorders, Psychiatric Hospitalization, Prodromal Symptoms, Cannabis Use
- Trial name
- YEAH (NCT03332966)
- Testing
- Psychiatric questionnaires, Semi-structured psychiatric interview
- Where
- 3 sites in Finland
- Volunteers
- 1,000 people
- Sponsor
- Finnish Institute for Health and Welfare
Ketamine Abuse, Psychotic Disorders
Substance Misuse To Psychosis for Ketamine (SToP-K)
Evidence suggests that repeated or chronic ketamine use, as compared to acute ketamine users, posed a higher clinical risk of developing psychotic disorders, potentially related to the underlying chronic N-methyl-D-aspartate…
- Conditions
- Ketamine Abuse, Psychotic Disorders, Substance Use Disorders, Schizophrenia
- Trial name
- NCT03485339
- Testing
- genome testing
- Where
- 2 sites in Hong Kong
- Volunteers
- 162 people
- Sponsor
- The University of Hong Kong
Psychosis, Clinical High Risk for Psychosis
Smartphone Applications Youth With Early Psychosis in Community Outpatient Settings
The project aims to test the utility of implementing a mobile health application ("mhealth app") in early psychosis care in the community outpatient setting and in the university medical center setting.
- Trial name
- BHCOEMobi (NCT03286595)
- Testing
- Mobi mHealth app
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Davis
Schizophrenia, Psychosis
Long-acting Injectable Antipsychotics for Mental Ill-Health in Pregnancy and Postpartum
The goal of this observational study is to learn about how long-acting injectable antipsychotic (LAIA) medications are affected by the changes that take place in the body during pregnancy, and how much an unborn baby is exposed…
- Conditions
- Schizophrenia, Psychosis, Mania, Pregnancy
- Trial name
- LAMP (NCT05766007)
- Where
- 6 sites in Nigeria
- Volunteers
- 168 people
- Sponsor
- University of Liverpool
Parkinson Disease
A Study of Tolerability and Efficacy of Cannabidiol on Motor Symptoms in Parkinson's Disease
The major purpose of this study is to assess the efficacy of CBD on motor symptoms of Parkinson's Disease (PD), and secondarily to study the safety and tolerability of CBD and other efficacy, particularly regarding tremor in PD.
- Trial name
- NCT03582137
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Colorado, Denver
Schizophrenia, Schizoaffective Disorder
Schizophrenia, Antipsychotic Treatment and the Risk for Diabetes Mellitus
This preliminary study aims to investigate the mechanism of higher rates of type 2 diabetes mellitus in patients with schizophrenia.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Delusional Disorder
- Trial name
- NCT00222807
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Psychosis, Schizophrenia
Motivational Interviewing for Patients With Acute Psychosis
Psychotic disorders are associated with high levels of distress, limitations in quality of life, and a high risk of chronification for those affected.
- Trial name
- MIA (NCT05911529)
- Testing
- Motivational Interviewing, Supportive conversations
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- Psychiatric University Hospital, Zurich