Clinical trials: Psychosocial Impairment
Schizophrenia, Insight Impaired
The Effects of Bimodal tDCS on Illness Severity, Insight, Functional Outcomes, Neurocognition and HRV in Schizophrenia
The study aimed to investigate the effects of bimodal anodal transcranial direct current stimulation (tDCS) over bilateral dorsolateral prefrontal cortex (DLPFC) on psychopathological symptoms, insight, psychosocial functioning…
- Conditions
- Schizophrenia, Insight Impaired, Psychotic Symptoms, Schizoaffective Disorder
- Trial name
- NCT03701100
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Hemodialysis Complication, Stress Disorders, Post-Traumatic
The Effect of Roy Adaptation-Based Nursing Intervention
Abstract Objective: The research was conducted to determine the effect of the nursing intervention, which was given to patients according to the Roy Adaptation Model, on patients' stress, psychosocial adjustment, and self-care…
- Conditions
- Hemodialysis Complication, Stress Disorders, Post-Traumatic, Psychosocial Impairment, Self Neglect
- Trial name
- NCT05568342
- Testing
- The Effect of Roy Adaptation-Based Nursing Intervention on Stress, Psychosocial Adjustment and Self-Care Power in Hemodialysis Patients: A Randomized Controlled Experimental Study
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep Islam Science and Technology University
PTSD, Functioning, Psychosocial
What Difficulties Do Children and Adolescents Experience in Everyday Activities After a Traumatic Event? Focus Groups and Delphi Survey for the Development of a Questionnaire on PTSD-related Functional Impairment
Post-traumatic Stress Disorder (PTSD) in children and adolescents is often associated with a myriad of significant impairments in daily functioning, including family relationships, school/work, leisure time activities, and social…
- Trial name
- NCT05984706
- Testing
- Focus groups and Delphi Questionnaire
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Children's Hospital, Zurich
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Suicide
Cognitive Inhibition, Psychosocial Interactions and Suicide Attempt in Elderly
The study aims to determine the correlation between the cognitive inhibition impairment and the history of suicide attempt in elderly depressed patients.
- Trial name
- OBSUIVAL (NCT02858427)
- Testing
- eye tracking, neuropsychological assessement, psychiatric assessment
- Where
- 2 sites in France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Insight Impaired
Characteristics of Illness Awareness in Anorexia Nervosa
Objective: To study the characteristics of illness awareness, its dimensions and its evolution in relation to clinical, cognitive and psychosocial variables in patients with anorexia nervosa.
- Trial name
- NCT06177262
- Testing
- cognitive behavioral therapy
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Mental Health Disorder, Mental Health Impairment
Youth FORWARD Phase 1 YRI and EPP Study
Objectives: The objectives of this research proposal are to study the delivery of an evidence-based mental health intervention in the alternate setting of youth employment programs tied to regional economic development and to…
- Conditions
- Mental Health Disorder, Mental Health Impairment, Psychosocial Impairment, Emotional Dysfunction
- Trial name
- NCT03603613
- Testing
- YRI, EPP
- Where
- Sierra Leone
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Boston College
Posttraumatic Stress Disorder
A Case Formulation Approach to Cognitive Processing Therapy
Recent estimates suggest that over 610,000 US Veterans treated by the Veterans Health Administration (VHA) suffer from PTSD, a disorder that can be chronic and debilitating.
- Trial name
- CF-CPT (NCT04407767)
- Testing
- Case Formulation plus Cognitive Processing Therapy, Cognitive Processing Therapy
- Where
- 8 sites in United States
- Volunteers
- 194 people
- Sponsor
- VA Office of Research and Development
Covid 19, Social Isolation
Community Health Workers Against COVID19
Randomized controlled trial among patients from family practices at risk of psychosocial suffering due to social distancing measures. Patients from the intervention group receive support from community health workers.
- Conditions
- Covid 19, Social Isolation, Mental Health Impairment
- Trial name
- NCT04426305
- Testing
- community health worker support, care as usual
- Where
- Belgium
- Volunteers
- 140 people
- Sponsor
- University Ghent
Adverse Childhood Experience, Endothelial Function (FMD)
Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity
Adverse childhood experiences (ACEs) represent highly stressful events in the first 18 years of life that include abuse, neglect, and household and community-level dysfunction.
- Conditions
- Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function
- Trial name
- PROMISE (NCT07244809)
- Testing
- Mitoquinone mesylate (MitoQ)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Schizophrenia, Schizoaffective Disorder
The Effects of tDCS on Auditory Hallucination, Insight, Neurocognitive Function and HRV in Patients With Schizophrenia
The study aimed to investigate whether transcranial direct current stimulation could modify auditory hallucination, insight, neurocognitive function, heart rate variability, psychosocial functioning and quality of life in…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Auditory Hallucination, Verbal, Neurocognitive Dysfunction
- Trial name
- NCT03388554
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Mental Health, Depression
rTMS for Emotional Difficulties in Verterans
Mental illness rarely occurs as a single, easily categorized condition. Instead, multiple disorders often co-occur. This complicates the treatment plan for many Veterans, especially those suffering the most severe dysfunction.
- Conditions
- Mental Health, Depression, rTMS, Anxiety
- Trial name
- rTMS (NCT03749967)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD, Depression
Impact of Modifiable Psychosocial Factors on Veterans' Long-term Trajectories of Functioning and Quality of Life
This study is Phase 3 of Project SERVE (Study Evaluating Returning Veterans' Experiences). Through two prior phases, SERVE has followed a cohort of post-9/11 Veterans since 2010 and has identified numerous risk and protective…
- Conditions
- PTSD, Depression, Chronic Pain, Alcohol Use Disorder
- Trial name
- SERVE:IMPACT (NCT03615222)
- Where
- 2 sites in United States
- Volunteers
- 377 people
- Sponsor
- VA Office of Research and Development
Chronic Obstructive Pulmonary Disease, Healthy Volunteers
Understanding Balance Impairment in COPD
This study is an observational study investigating the mechanisms of balance problems in people with COPD and how COPD impacts them living their daily lives.
- Trial name
- NCT05984498
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Teesside University
Breast Cancer, Cognitive Dysfunction
eHealth Interventions for Breast Cancer Cognitive Impairment
This study investigates the effectiveness of integrating a cognitive rehabilitation module into a digital psychosocial intervention for recently diagnosed breast cancer patients.
- Trial name
- ICOgnition (NCT06103318)
- Testing
- ICOgnition
- Volunteers
- 176 people
- Sponsor
- Institut Català d'Oncologia
Head and Neck Cancer, Body Image Disturbance
Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT
In this multi-center randomized clinical trial, head and neck cancer (HNC) survivors with clinically significant body image distress (BID) (N=180) will be randomized to BRIGHT (a brief video tele-cognitive behavioral therapy…
- Conditions
- Head and Neck Cancer, Body Image Disturbance, Body Image, Survivorship
- Trial name
- BRIGHT (NCT05442957)
- Testing
- BRIGHT, Attention Control
- Where
- 5 sites in United States
- Volunteers
- 180 people
- Sponsor
- Medical University of South Carolina
Mild Cognitive Impairment
Support Groups for Patients With Mild Cognitive Impairment and Their Partners
This study aims at developing and evaluating a support group program for patients with mild cognitive impairment (MCI) and their partners. These patients have defective memory function but are not demented.
- Trial name
- NCT00285753
- Testing
- support groups
- Where
- 2 sites in Netherlands
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Temporomandibular Disorder, Pain
Evaluation of an Intra Auricular Device as a Treatment for Painful Temporo-Mandibular Disorders
Background: An innovative, non-invasive, and reversible Intra Auricular Device (IAD) has recently been introduced to treat temporomandibular muscle and joint disorders.Aim: To evaluate the effects of the IAD on pain, psychosocial…
- Conditions
- Temporomandibular Disorder, Pain, Psychosocial Impairment, Myofascial Pain
- Trial name
- IAD (NCT05365932)
- Testing
- Intra auricular device (IAD)
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Federico II University
Cognitive Changes Due to Organic Disorder (Finding), Dementia
Gerontology Research Programme: The Singapore Longitudinal Ageing Studies (SLAS I & II)
The Gerontology Research Programme (GRP) in the National University Singapore's Department of Psychological Medicine, was formed to coordinate and facilitate the conduct of multi-disciplinary research on in a wide range of…
- Conditions
- Cognitive Changes Due to Organic Disorder (Finding), Dementia, Mild Cognitive Impairment, Frailty
- Trial name
- SLAS (NCT03405675)
- Testing
- SLAS 1, SLAS 2
- Where
- Singapore
- Volunteers
- 6,183 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
HIV/AIDS, Aging
Psychosocial Intervention for Older HIV+ Adults With HAND
CTNPT 029 will test the feasibility and acceptability of cognitive remediation group therapy in older adults living with HIV who have been diagnosed with HIV-associated neurocognitive disorder (HAND).
- Conditions
- HIV/AIDS, Aging, Mild Cognitive Impairment, Group, Peer
- Trial name
- IN-HAND (NCT03483740)
- Testing
- CRGT, HIV group therapy
- Where
- 3 sites in Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto