Clinical trials: Psychosocial Stressors
Depressive Symptoms, Anxiety
The Impact of PM+For Moms Intervention on Improving Mother's Mental Health in Zambia (PM+FM)
CMHD are particularly prevalent among women, posing a major threat to their own and their children's wellbeing. Despite the high prevalence of CMHD and the existence of effective treatments, interventions supporting women living…
- Conditions
- Depressive Symptoms, Anxiety, Trauma, Psychological
- Trial name
- PM+FM (NCT05627206)
- Testing
- Problem Management + For Moms
- Where
- Zambia
- Volunteers
- 270 people
- Sponsor
- Swiss Tropical & Public Health Institute
Infertility Primary, Psychosocial Stressor
Psychosocial Intervention in Assisted Reproduction Treatments
The aim of the study was to evaluate and compare different strategies of psychosocial intervention for patients undergoing IVF treatment in a private fertility clinic.
- Conditions
- Infertility Primary, Psychosocial Stressor, Anxiety Depression
- Trial name
- NCT04572659
- Testing
- Group psychosocial intervention, Couple psychosocial intervention
- Volunteers
- 174 people
- Sponsor
- Vida Recoletas Sevilla
Cancer, Psychosocial Distress
Psychosocial Effects of a Trauma-Informed Artificial Intelligence-Supported Chatbot in Adults Newly Diagnosed With Cancer
The goal of this clinical trial is to evaluate whether a trauma-informed, artificial intelligence-supported chatbot can reduce psychological distress and unmet psychosocial needs in adults newly diagnosed with cancer.: Does the…
- Conditions
- Cancer, Psychosocial Distress, Trauma and Stress Related Disorders, Anxiety
- Trial name
- NCT07583069
- Testing
- Trauma-Informed AI-Supported Chatbot
- Volunteers
- 62 people
- Sponsor
- Koç University
Moral Injury, TEPT
A Comprehensive Group Intervention for Psychosocial Personnel at Risk of Stress and Moral Injury
The objective of this randomized controlled trial is to evaluate the effectiveness of the CARE-MI group intervention in reducing symptoms of post-traumatic stress and moral injury in support staff working with individuals…
- Trial name
- CARE-MI-PsychS (NCT07140263)
- Testing
- CARE MI, TAU: Treatment as usual
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Blood Cancers, Leukemia
A Manualised Post-Traumatic Growth Intervention For People With Hematological Cancers In Greece
This clinical trial aims to determine whether a manualised group intervention for people with blood cancers can help them experience positive psychological changes following their diagnosis, known as post-traumatic growth.
- Conditions
- Blood Cancers, Leukemia, Lymphoma, Bone Marrow Transplant
- Trial name
- NCT07814170
- Testing
- A manualised post-traumatic growth intervention for people with hematological cancers
- Where
- 2 sites in Greece
- Volunteers
- 80 people
- Sponsor
- University of West Attica
Moral Injury
Comparing Two Moral Injury Treatments
Purpose of this study: The purpose of this study is to evaluate the effectiveness of two psychological treatments for moral injury: Acceptance and Commitment Therapy for Moral Injury and Present Centered Therapy for Moral Injury.
- Trial name
- NCT07710521
- Testing
- Acceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- VA Eastern Colorado Health Care System
Stress, Psychological, Inflammation
Does Propranolol Attenuate Inflammatory Responses to a Psychological Stressor?
This randomized, double-blind, placebo-controlled study of propranolol will shed important light on how sympathetic nervous system (SNS) activation influences psychological and inflammatory responses to acute stress.
- Conditions
- Stress, Psychological, Inflammation, Cortisol, Sympathetic Nervous System
- Trial name
- NCT02972554
- Testing
- Propanolol hydrochloride
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
PTSD, Functioning, Psychosocial
What Difficulties Do Children and Adolescents Experience in Everyday Activities After a Traumatic Event? Focus Groups and Delphi Survey for the Development of a Questionnaire on PTSD-related Functional Impairment
Post-traumatic Stress Disorder (PTSD) in children and adolescents is often associated with a myriad of significant impairments in daily functioning, including family relationships, school/work, leisure time activities, and social…
- Trial name
- NCT05984706
- Testing
- Focus groups and Delphi Questionnaire
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Children's Hospital, Zurich
Stress, Psychological Distress
Implementation of Self Help Plus in Adult Syrian Refugees in Turkey (RE-DEFINE)
This study evaluates the effectiveness and cost-effectiveness of the SH+ in Arabic speaking people including Syrians under the temporary protection of Republic of Turkey and other Arabic speaking immigrants and asylum seekers…
- Trial name
- RE-DEFINE (NCT03587896)
- Testing
- Self Help Plus
- Where
- Turkey (Türkiye)
- Volunteers
- 642 people
- Sponsor
- Istanbul Sehir University
Major Depressive Disorder, Anxiety Disorder
The Relationship Between Emotion Regulation and Psychiatric Disorder in Youth
According to the increasing worldwide prevalence rate of psychiatric disorders in youth, the mental health of youth is becoming more and more important.
- Conditions
- Major Depressive Disorder, Anxiety Disorder, Attention Deficit Hyperactivity Disorder (ADHD), Adjustment Disorder
- Trial name
- NCT06271954
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Prostate Cancer, Psychosocial Stressor
Feasibility of Technology-Based SSIP in Prostate Cancer Patients
The goal of this pilot study is to assess the perceived usability of a smartphone application called WINGS targeting psychosocial distress and well-being in prostate cancer patients and their social network.
- Trial name
- NCT05720832
- Testing
- WINGS-IP1 Smartphone Application
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- Wings Health AG
Mental Health Disorder, PTSD
Psychosocial and Economic Impacts of Narrative Exposure Therapy for Violence Survivors in Eastern DRC
The objective of the study is to evaluate the impact of Narrative Exposure Therapy (NET) delivered by local counselors, on the mental health and socio-economic empowerment of survivors of Sexual and Gender Based Violence (SGBV)…
- Conditions
- Mental Health Disorder, PTSD, Depression Anxiety Disorder, Gender-based Violence
- Trial name
- NCT04841031
- Testing
- NET Treatment, Alternative Intervention
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 1,053 people
- Sponsor
- World Bank
Stress, Psychological
Self Help Plus for Asylum Seekers and Refugees in Europe
Background The flow of asylum seekers and refugees moving to European and bordering countries has progressively increased in the last years.
- Trial name
- REDEFINE (NCT03571347)
- Testing
- Self Help Plus, Enhanced Treatment As Usual
- Where
- Italy
- Volunteers
- 459 people
- Sponsor
- Universita di Verona
Posttraumatic Stress Disorder
A Case Formulation Approach to Cognitive Processing Therapy
Recent estimates suggest that over 610,000 US Veterans treated by the Veterans Health Administration (VHA) suffer from PTSD, a disorder that can be chronic and debilitating.
- Trial name
- CF-CPT (NCT04407767)
- Testing
- Case Formulation plus Cognitive Processing Therapy, Cognitive Processing Therapy
- Where
- 8 sites in United States
- Volunteers
- 194 people
- Sponsor
- VA Office of Research and Development
Psycho-Oncology, Visceral Cancer
Optimized Psycho-oncological Care Through an Interdisciplinary Care Algorithm
Adequate, needs-oriented psycho-oncological care contributes to reducing the burden on cancer patients and their relatives and to improving the quality of life.
- Conditions
- Psycho-Oncology, Visceral Cancer, Screening, Psychosocial Stressor
- Trial name
- OptiScreen (NCT04638699)
- Testing
- OptiScreen training
- Where
- Germany
- Volunteers
- 900 people
- Sponsor
- Hannover Medical School
Anxiety, Depressive Symptoms
Rare Group Problem Management Plus
Participants are being asked to be in the study if they are the parent or legal guardian of a child (>1 year or <18 years old) with a rare condition.
- Conditions
- Anxiety, Depressive Symptoms, Post-traumatic Stress Disorder, Problems Psychosocial
- Trial name
- Group PM+ (NCT06548022)
- Testing
- Rare Group Problem Management Plus
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Children's National Research Institute
Trauma and Stress-related Disorders, Food Insecurity
MISAPSY: Childhood Maltreatment, Food Insecurity, Psychological Distress and Professional Integration Among Socioeconomically Disadvantaged Young Adults
The MISAPSY study (Childhood Maltreatment, Food Insecurity, Psychological Distress and Professional Integration Among Socioeconomically Disadvantaged Young Adults) aims to model the complex interrelations between child…
- Conditions
- Trauma and Stress-related Disorders, Food Insecurity, Child Maltreatment, Psychological Distress
- Trial name
- PRESPA (NCT07427524)
- Testing
- Food Assistance, Psychological Follow-Up
- Where
- 6 sites in France
- Volunteers
- 70 people
- Sponsor
- University of Lorraine
PTSD
Written Exposure Therapy Versus Prolonged Exposure: a Non-inferiority Trial
The goal of this study is to examine whether a brief, exposure-based treatment (Written Exposure Therapy) approach is just as effective in the treatment of posttraumatic stress disorder (PTSD) compared with a more commonly used…
- Trial name
- NCT03962504
- Testing
- trauma-focused treatment
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- VA Office of Research and Development
Mental Health, Depression
rTMS for Emotional Difficulties in Verterans
Mental illness rarely occurs as a single, easily categorized condition. Instead, multiple disorders often co-occur. This complicates the treatment plan for many Veterans, especially those suffering the most severe dysfunction.
- Conditions
- Mental Health, Depression, rTMS, Anxiety
- Trial name
- rTMS (NCT03749967)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD, Depression
Impact of Modifiable Psychosocial Factors on Veterans' Long-term Trajectories of Functioning and Quality of Life
This study is Phase 3 of Project SERVE (Study Evaluating Returning Veterans' Experiences). Through two prior phases, SERVE has followed a cohort of post-9/11 Veterans since 2010 and has identified numerous risk and protective…
- Conditions
- PTSD, Depression, Chronic Pain, Alcohol Use Disorder
- Trial name
- SERVE:IMPACT (NCT03615222)
- Where
- 2 sites in United States
- Volunteers
- 377 people
- Sponsor
- VA Office of Research and Development