Clinical trials: Psychotherapy, open to volunteers
Major Depression
Modular Intervention for Depression Study
The goal of this psychotherapy clinical trial is to evaluate whether a algorithm-based personalized modular psychotherapy is more effective than usual individual psychotherapy in treating major depressive disorder complicated by…
- Trial name
- MIND (NCT07380451)
- Testing
- Modular Intervention for Depression Therapy (MIND Therapy), Psychotherapy as Usual (TAU)
- Where
- 5 sites in Chile
- Volunteers
- 150 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Breast Cancer, Prostate Cancer
A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer
The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT).
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT07225309
- Testing
- Meaning-Centered Psychotherapy for Latinos /MCP-L
- Where
- 2 sites in United States, Mexico
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer
Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies
This phase III clinical trial will evaluate the impact on survival of adding chaplain-provided spiritual care or psychotherapy/meditation to standard-of-care (SOC) and palliative measures, plus chemotherapy if recommended, and…
- Trial name
- SPC (NCT07290491)
- Testing
- Chaplain-Provided Spiritual Care, Psychotherapy and Meditation Intervention
- Where
- United States
- Volunteers
- 854 people
- Sponsor
- The Methodist Hospital Research Institute
Anxiety, Hospitalization
Virtual Nature Versus Guided Imagery for Anxiety and Well-Being in Hospitalized Older Adults
Long hospital stays can be difficult for older adults. Being confined to a ward, with limited mobility and little access to the outdoors, may contribute to anxiety, low mood, and reduced well-being.
- Conditions
- Anxiety, Hospitalization, Quality of Life, Psychological Distress
- Trial name
- NCT07765355
- Testing
- Immersive virtual reality nature exposure, Guided imagery
- Where
- 2 sites in Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Breast Cancer, Ovarian Cancer
Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence
The goal of this clinical trial is to test whether psilocybin along with therapy in women with early breast cancer and ovarian cancer in remission can improve their fear of recurrence.
- Trial name
- NCT06430541
- Testing
- Psilocybin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Suicide, Trauma
Integrated Suicide & Trauma Therapy for Suicide Risk
The investigators have developed a novel suicide intervention, Integrated Suicide and Trauma Therapy (ISTT). ISTT combines Brief-Skills for Safer Living (Brief-SfSL)-a promising method to enhance coping skills and reduce…
- Conditions
- Suicide, Trauma, Major Depressive Disorder
- Trial name
- ISTT (NCT05613972)
- Testing
- Integrated Suicide and Trauma Therapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Unity Health Toronto
Alcohol-Related Disorders, Alcoholism
Comparing Combined Behavioral Intervention and Ericksonian Hypnotherapy for Alcohol Addiction
This clinical study is being conducted to compare the effectiveness of two psychological treatments for alcohol addiction: Combined Behavioral Intervention (CBI) and Ericksonian Hypnotherapy (EH).
- Conditions
- Alcohol-Related Disorders, Alcoholism, Substance-related Disorders
- Trial name
- NCT06916754
- Testing
- Combined Behavioral Intervention, Ericksonian Hypnotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Beykoz University
Multiple Sclerosis, Neurorehabilitation
Comprehensive Therapeutic Program For People With Multiple Sclerosis
This study investigates the effectiveness of an intensive multidisciplinary rehabilitation program for people with multiple sclerosis (PwMS).
- Conditions
- Multiple Sclerosis, Neurorehabilitation, Rehabilitation, Rehabilitation Exercise
- Trial name
- BIB_MS (NCT07248657)
- Testing
- Outpatient physiotherapy, group psychotherapy
- Where
- Czechia
- Volunteers
- 26 people
- Sponsor
- Charles University, Czech Republic
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Prehabilitation
Multimodal Prehabilitation Program That Combines Physical Exercise, Psychological Intervention and Nutritional Support to Improve the Response to Neoadjuvant Chemoterhapy in Early Breast Cancer Patients
The aim of this clinical trial is to evaluate whether following a multimodal prehabilitation program including physical exercise, nutritional support and psychological intervention during neoadjuvant chemotherapy in breast cancer…
- Trial name
- DIANA (NCT07107594)
- Testing
- Multimodal prehabilitation
- Where
- Spain
- Volunteers
- 214 people
- Sponsor
- Hospital Clinic of Barcelona
Posttraumatic Stress Disorder
The Predictive Role of Immune-inflammatory Biomarkers and Their Interaction With the Oxytocin System in Trauma-related Psychotherapy Responsiveness
Despite a range of treatments for posttraumatic stress disorder (PTSD), only a small proportion of patients reach full symptomatic remission.
- Trial name
- NCT06348472
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Shalvata Mental Health Center
Suicide Risk
Suicidal Risk in Adults in Panama: Validation of a Clinical Intervention Protocol
This study aims to validate MBT as an effective and viable intervention for implementation in public health services, with the potential to directly impact suicide prevention policies in the region.
- Trial name
- NCT07717320
- Testing
- Mentalization-Based Therapy (MBT), Treatment as Usual (TAU)
- Where
- 2 sites in Panama
- Volunteers
- 300 people
- Sponsor
- Fundación Judío Panameña (JUPA)
Perinatal Depression
Clinical and Cost-effectiveness of an Online Self-help Intervention and a Face-to-face Intervention Versus Usual Care in Mothers at Moderate Risk for Perinatal Depression
The perinatal period (pregnancy and the first postnatal year) (O'Hara \& Wisner, 2014) involves important changes and considerable challenges for parents (Milgrom \& Gemmill, 2015).
- Trial name
- MaMHI (NCT07027761)
- Testing
- Online self-help, Maternal Mental Health Intervention (MaMHI), Usual Care
- Where
- Belgium
- Volunteers
- 210 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Borderline Personality Disorder (BPD)
Internal Family Systems Therapy for Borderline Personality Disorder
Borderline Personality Disorder (BPD) involves intense emotional ups and downs, unstable relationships, impulsivity, and a poor sense of self.
- Trial name
- IFS for BPD (NCT07342907)
- Testing
- Internal family systems therapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Waypoint Centre for Mental Health Care
Bipolar Disorder
Pragmatic Patient-oriented Extension Study of Dialectical Behavior Therapy Booster Sessions for Youth With and/or at Familial Risk for Bipolar Disorder
The study intervention is DBT adapted for youth with and/or at familial risk for bipolar disorder. Participants will have completed one full year of DBT in a previous study. This study is examining use of booster sessions.
- Trial name
- DB2 (NCT05627492)
- Testing
- Dialectical behavioral therapy
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Centre for Addiction and Mental Health
Aquired Brain Injury, Stroke
Group-based Emotional Awareness and Expression Therapy to Support Recovery After Acquired Brain Injury: A Clinical Development and Evaluation Study
Difficulties in understanding and managing emotions may hinder recovery, rehabilitation, and participation in everyday life after acquired brain injury (ABI).
- Conditions
- Aquired Brain Injury, Stroke, MTBI - Mild Traumatic Brain Injury, mTBI
- Trial name
- NCT07852936
- Testing
- TAU + Group Therapy (EAET), Treatment as Usual (TAU)
- Where
- Sweden
- Volunteers
- 110 people
- Sponsor
- Uppsala University
Suicide Prevention, Suicide
Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk: Aim 2b
This is a second pilot study being completed based on lessons learned from the Aim 2a feasibility pilot study (NCT06941311). Following modifications, the investigators are testing the acceptability, feasibility, and preliminary…
- Conditions
- Suicide Prevention, Suicide, Self-Injurious Behavior, Behavioral Symptoms
- Trial name
- NCT07506460
- Testing
- Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP), Youth-Nominated Support Team
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Michigan
Psychological Trauma, Stress Disorders, Post-Traumatic; Mental Disorders
Trauma-Focused Group Therapy for Adults With Trauma-Related Symptoms in Primary Care
Psychological trauma is common and can lead to long-lasting emotional distress, difficulties in daily functioning, and reduced quality of life.
- Trial name
- NCT07757334
- Testing
- Trauma-Focused Group Intervention, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Luis Eduardo Estévez Cachafeiro
Anorexia Nervosa, Anorexia in Adolescence
Family-based Telemedicine vs. Inpatient Anorexia Nervosa Treatment (FIAT)
The FIAT study is funded by the Innovationsfonds of the German Ministry of Health via the DLR Project Management Agency. The study will be conducted in up to 21 hospitals across Germany and in collaboration with 10 German public…
- Trial name
- FIAT (NCT06759402)
- Testing
- Family based treatment, Inpatient multimodal therapy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
OCD, Obsessive - Compulsive Disorder
Effect of Emotion-Focused Acceptance and Commitment Therapy on Obsessive-Compulsive Disorder Symptom Severity
This study aims to investigate the effect of Emotion-Focused Acceptance and Commitment Therapy (ACT) group psychotherapy on obsessive-compulsive disorder (OCD) symptom severity.
- Trial name
- ACT-OCD (NCT07622654)
- Testing
- Emotion-Focused Acceptance and Commitment Therapy (ACT) Group Psychotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Mehmet Emrah Karadere
Burnout, Burnout, Healthcare Workers
Psilocybin-Assisted Therapy for Physician Well-Being and Burnout
Through an open-label study involving a small group of UCSD physicians experiencing burnout, the investigators will evaluate the feasibility, safety, and preliminary effectiveness of PAT to reduce burnout symptoms.
- Trial name
- PAT-B (NCT06814522)
- Testing
- Psilocybin, [3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate, Real-time Biofeedback
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego