Clinical trials: Psychotic Symptoms
Mental Disorder, Mental Stress
Virtual Agents-based Digital Interventions to Improve Health
KANOPEE is a free smartphone application providing screening, follow-up tools and autonomous digital interventions to lower psycho-social stress and its repercussions on sleep and behaviors in the general population.
- Conditions
- Mental Disorder, Mental Stress, Insomnia, Depression
- Trial name
- KANOPEE (NCT05074901)
- Testing
- digital behavioral intervention
- Where
- France
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Schizophrenia
Double Blind, Placebo-controlled Study of Raloxifene for Negative Symptoms of Schizophrenia in Postmenopausal Women
Primary objective: To assess the efficacy of adding raloxifene as an adjunct to antipsychotic treatment to improve negative symptoms of schizophrenia in postmenopausal women.
- Trial name
- NCT01041092
- Testing
- raloxifene
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Fundació Sant Joan de Déu
Schizophrenia
Multicenter, Open-Label, Randomised, Haloperidol-controlled Study to Evaluate Seroquel as Mono-Therapy in the Treatment of Agitated Symptoms in the Patients With Acute Episode of Schizophrenia
This study attempts to observe the efficacy (response time) and safety of the second-generation antipsychotic agent-quetiapine versus the first-generation antipsychotic agent-haloperidol, in treating acute schizophrenia episode…
- Trial name
- NCT00631722
- Testing
- Quatiapine Fumarate, Haloperidol
- Volunteers
- 80 people
- Sponsor
- Peking University
Trauma, Psychological, Psychosis
A Comprehensive Third-generation Intervention for People With Psychosis and Post-traumatic Stress Symptoms
Existing data suggest that both trauma and Post-Traumatic Stress Disorder (PTSD) are very common among individuals with psychosis.
- Trial name
- IITG-PPT (NCT05619822)
- Testing
- TAU + A comprehensive third-generation intervention, TAU
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Complutense de Madrid
Schizoaffective Disorder, Schizophrenia
Genetic Study of Schizophrenia
This large ongoing study at NIMH investigates the neurobiology of schizophrenia by identifying susceptibility genes, evaluating their impact on brain function to better understand how to treat and prevent this illness.
- Trial name
- NCT00001486
- Where
- United States
- Volunteers
- 4,914 people
- Sponsor
- National Institute of Mental Health (NIMH)
Weight Gain, Sialorrhea
FazaClo Outcomes in the Control of Schizophrenia (FOCUS) Study Survey
AZUR Pharma has received several reports from practicing psychiatrists prescribing FazaClo showing that FazaClo patients start losing body weight instead of keep gaining it, after being switched from other clozapine products or…
- Trial name
- FOCUS (NCT00683891)
- Testing
- FazaClo (clozapine, USP) ODT
- Where
- 2 sites in United States
- Sponsor
- Azur Pharma, Inc
Schizophrenia
The Effects of tDCS on Illness Awareness in Schizophrenia
This is a novel study that seeks to explore the clinical and functional imaging effects of transcranial direct current stimulation (tDCS) on illness awareness or anosognosia in schizophrenia, arguably the most treatment-resistant…
- Trial name
- NCT02848885
- Testing
- Active TDCS
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia
High-Dose Oral Ziprasidone Versus Conventional Dosing in Participants With Residual Schizophrenia Symptoms
The primary aims of this study are to assess tolerability of ziprasidone dose escalation to 320 milligrams per day (mg/d) compared to continued standard treatment (placebo) as measured by the Side Effect Checklist, Simpson Angus…
- Trial name
- HDZ (NCT00403546)
- Testing
- Ziprasidone 80-160 mg/d, Ziprasidone 160 mg/d
- Where
- 9 sites in United States
- Volunteers
- 131 people
- Sponsor
- Donald C. Goff, MD
Chronic Disease, Quality of Life
Quality of Life in Patients With Chronic Disease
To improve HRQoL in patients with chronic diseases, a comprehensive understanding of the association between HRQoL and chronic diseases is vital.
- Conditions
- Chronic Disease, Quality of Life, Cardiovascular Diseases, Diabetes
- Trial name
- QAPICHE (NCT03925805)
- Where
- Belgium
- Volunteers
- 543 people
- Sponsor
- University Ghent
Schizophrenia, Clozapine
Effect of Exercise on Clinical Symptoms, Cognitive Performance, and Quality of Life in Schizophrenia Patients Treated With Clozapine
This prospective study aims to investigate the effects of exercise on clinical symptoms, cognitive performance, and quality of life in schizophrenia patients treated with Clozapine.
- Conditions
- Schizophrenia, Clozapine, Exercise
- Trial name
- NCT06573320
- Testing
- physical exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Schizophrenia
Prevention of Relapse With Injectable Paliperidone Palmitate Versus Oral Antipsychotics
The purpose of this study is to assess the efficacy (how well the drug works; primarily through the time to relapse) of long-acting injectable paliperidone palmitate compared to treatment as usual with orally administered…
- Trial name
- PROSIPAL (NCT01081769)
- Testing
- paliperidone palmitate injection, oral antipsychotics
- Where
- 94 sites in Austria, Belgium and 23 more
- Volunteers
- 769 people
- Sponsor
- Janssen-Cilag International NV
Psychosomatic Disorder, Mental Disorder
Effectiveness and Equivalence of an Internet-based Virtual Classroom Intervention for Psychosomatic Aftercare
Outpatient psychosomatic aftercare after inpatient rehabilitation pursues the goal of helping patients to transfer the achieved rehabilitation result in everyday life and professional life.
- Trial name
- NCT04989842
- Testing
- Curriculum Hannover
- Where
- Germany
- Volunteers
- 6,023 people, healthy volunteers welcome
- Sponsor
- Dr. Becker Hospital Group
Impulsivity, Active Suicidal Ideation
Impulsivity and Thought Process Disorder in Patients With Active Suicidal Ideation and Depression
This study is dedicated to achieving a better understanding of how the brain processes information. Specifically, the investigators are studying cognitive function, thought process, and impulsivity in people with and without…
- Conditions
- Impulsivity, Active Suicidal Ideation, Depression
- Trial name
- NCT01770600
- Testing
- Riperidone
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Psychosis, Suicide
Youth Nominated Support Team
This study aims to adapt the current Youth-Nominated Support Team (YST) manual used to treat suicide risk for people at clinical high risk for psychosis.
- Conditions
- Psychosis, Suicide, Health Care Utilization, Family Members
- Trial name
- YST (NCT05558332)
- Testing
- Youth-Nominated Support Teams for CHR
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, Irvine
Schizophrenia
The Efficacy And Safety Of Intramuscular Ziprasidone For Three Days In Patients With Psychotic Agitation
1. The title of this study is a multi-center,non randomized,open-labeled,intervention study:the efficacy and safety of intramuscular ziprasidone for three days in patients with acute psychotic agitation. 2.
- Trial name
- NCT02935998
- Testing
- Ziprasidone
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Yang Fude
Psychotic Disorders, Schizophrenia
FAST-A Study to Evaluate the Efficacy and Safety of Quetiapin IR in Patients With Acute Psychosis
The purpose of this study is to compare the efficacy of quetiapine IR, following rapid titration versus conventional titration in patients with acute psychosis
- Conditions
- Psychotic Disorders, Schizophrenia, Bipolar Disorder
- Trial name
- FAST (NCT00486798)
- Testing
- Quetiapine, Rating Scales, Self Assessment Form
- Where
- 13 sites in Sweden
- Sponsor
- AstraZeneca
Schizophrenia
PREvent First Episode Relapse (PREFER)
Many patients who have recently received a diagnosis of schizophrenia (e.g., "first-episode schizophrenia") respond very well to their antipsychotic medication when they are acutely ill.
- Trial name
- NCT00220714
- Testing
- atypical antipsychotics:oral vs. long-acting route, Family Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- State University of New York - Downstate Medical Center
Schizophrenia, Schizoaffective Disorder
MEtformin and Lorcaserin for WeighT Loss in Schizophrenia
Purpose: The purpose of this study is to test new pharmacologic strategies for weight loss in patients with schizophrenia, a population for which no current weight-loss treatments have gained widespread use.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Overweight
- Trial name
- MELT (NCT02796144)
- Testing
- Lorcaserin, Metformin
- Where
- 4 sites in United States
- Volunteers
- 71 people
- Sponsor
- University of North Carolina, Chapel Hill
Schizophrenia Disorder
dACC-Targeted Temporal Interference for Negative and Cognitive Symptoms in Schizophrenia
This randomized, double-blind, sham-controlled trial aims to evaluate the efficacy and safety of dorsal anterior cingulate cortex-targeted temporal interference stimulation in individuals with schizophrenia.
- Trial name
- NCT07658898
- Testing
- Temporal Interference Stimulation
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University
Schizophrenia, Psychosis
Long-acting Injectable Antipsychotics for Mental Ill-Health in Pregnancy and Postpartum
The goal of this observational study is to learn about how long-acting injectable antipsychotic (LAIA) medications are affected by the changes that take place in the body during pregnancy, and how much an unborn baby is exposed…
- Conditions
- Schizophrenia, Psychosis, Mania, Pregnancy
- Trial name
- LAMP (NCT05766007)
- Where
- 6 sites in Nigeria
- Volunteers
- 168 people
- Sponsor
- University of Liverpool
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.