Clinical trials: Psychotic Symptoms
Schizophrenia, Obsessive Compulsive Disorder
Chronic Schizophrenia With Obsessive-Compulsive Symptoms: Comorbidity or a Subtype?
Evaluating the prevalence and characteristics of obsessive-compulsive (OC) symptoms in patients with chronic schizophrenia
- Trial name
- NCT00269464
- Sponsor
- Sheba Medical Center
Schizophrenia
Control of Metabolic and Cardiovascular Risk in Patients With Schizophrenia and Overweight
To analyse the progress of modifiable metabolic risk factors (Blood pressure, cigarette smoking, waist perimeter, BMI, glycemia and lipidic profile) in schizophrenic patients with overweight for 12 months.
- Trial name
- CRESSOB (NCT00584519)
- Testing
- non-interventional
- Volunteers
- 430 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Schizophrenia and Predominant Negative Symptoms
Accelerated Neuromodulation Therapy for Negative Symptoms of Schizophrenia
The goal of this clinical trial is to learn if an accelerated form of neuromodulation therapy can help improve negative symptoms of schizophrenia.
- Trial name
- TMSNS (NCT07428460)
- Testing
- Neuronavigated Intermittent Theta Burst Stimulation, BEAM-F3 Intermittent theta burst stimulation
- Where
- 3 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Douglas Mental Health University Institute
Obesity, Schizophrenia
Lifestyle Modification for Weight Loss in Schizophrenia
The purpose of this study is to find out how effective lifestyle modification group therapy is on reducing body weight when compared to usual care in individuals with schizophrenia and/or schizoaffective disorder.
- Conditions
- Obesity, Schizophrenia, Schizoaffective Disorder
- Trial name
- NCT00990925
- Testing
- Nutritional Lifestyle Modification Group, Usual Care
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Yale University
Schizophrenia
Genetic Expression in Schizophrenics Treated With SSRI Augmentation: Relationship to Clinical and Cognitive Function
In our study we aim to examine the effect of SSRI augmentation on negative symptoms and cognitive function in schizophrenia patients as well as to examine the effect of SSRI augmentation on the RNA and protein products in…
- Trial name
- NCT00645580
- Testing
- Fluvoxamine
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Sha'ar Menashe Mental Health Center
Schizophrenia, Bipolar Disorder
Evaluation of A Statewide Program to Prevent Early Mortality and to Promote Fitness in Persons With SMI
The goal of this project, which has not changed, is to evaluate the statewide implementation of a two-component intervention (health promotion plus academic detailing) with respect to consumer outcomes and changes in provider…
- Conditions
- Schizophrenia, Bipolar Disorder, Schizoaffective Disorder
- Trial name
- NCT02334280
- Testing
- In SHAPE
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Mental Health
Patient Generated Goals in Mental Health: Better Outcomes?
Researchers believe that clinical care can be improved by engaging patients and families directly in planning the care process. Engagement efforts have included asking patients/families to provide information about whether they…
- Trial name
- NCT03527914
- Testing
- Goal Based Outcomes, Treatment as Usual
- Where
- Canada
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Depression
Empowering Health: Acute Psychological Effects of an Electromyostimulation-Whole-Body-Workout
The study investigates the acute psychological effects of a whole-body-workout using Electromyostimulation (EMS) in participants with depression and healthy individuals.
- Trial name
- NCT04211493
- Testing
- whole-body-workout, EMS
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Schizophrenia, Insight Impaired
The Effects of Bimodal tDCS on Illness Severity, Insight, Functional Outcomes, Neurocognition and HRV in Schizophrenia
The study aimed to investigate the effects of bimodal anodal transcranial direct current stimulation (tDCS) over bilateral dorsolateral prefrontal cortex (DLPFC) on psychopathological symptoms, insight, psychosocial functioning…
- Conditions
- Schizophrenia, Insight Impaired, Psychotic Symptoms, Schizoaffective Disorder
- Trial name
- NCT03701100
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Mental Disorder in Adolescence, Depression in Adolescence
Improvement of Mental Health in Adolescents Using E-health Interventions
the goal of this cluster randomized controlled trial is to assess the effectiveness of smartphone application in reducing the symptoms of Anxiety and depression among adolescents. The main objectives of this trial are: 1.
- Conditions
- Mental Disorder in Adolescence, Depression in Adolescence, Anxiety Disorders
- Trial name
- NCT05865834
- Testing
- A smartphone application, Pictorial educational leaflets
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Chronic Pain, Schizophrenia
CBT-CP for Veterans With SMI
Chronic musculoskeletal pain has a highly negative impact on Veterans, especially those with serious mental illness (SMI). Chronic musculoskeletal pain leads to poorer mental and physical health-related functioning, representing…
- Conditions
- Chronic Pain, Schizophrenia, Psychotic Disorders, Bipolar Disorder
- Trial name
- CP-SMI (NCT06758414)
- Testing
- Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Health & Wellness (H&W)
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- VA Office of Research and Development
Psychosis, Aggression
Haloperidol vs. Risperidone in the Treatment of Aggression in Psychotic Inmates
This study examines the efficacy of haldol versus risperdal in the treatment of aggression in psychotic prison inmates. It is hypothsized that risperdal will be more effective in decreasing aggression than haldol.
- Trial name
- NCT00203775
- Testing
- risperidone
- Where
- United States
- Sponsor
- University of Connecticut
Alzheimer Disease
Home-based Transcranial Direct Current Stimulation (tDCS) for Behavioral Symptoms in Alzheimer's Disease and Related Dementias (ADRD)
The purpose of this study is to assess acceptability, and safety of providing tDCS to ADRD patients with behavioral symptoms and to assess the efficacy of tDCS for ADRD-related symptoms, mainly behavioral symptoms.
- Trial name
- NCT05478681
- Testing
- active tDCS
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas Health Science Center, Houston
Schizophrenia; Negative Type
An Open-Label, Single Arm Study of the Efficacy of Accelerated Intermittent Theta Burst Stimulation in Schizophrenia Patients With Persistent Negative Symptoms
Schizophrenia patients commonly present with persistent negative symptoms which remain the main reason for dysfunction after recovery from an acute episode of psychotic symptoms.
- Trial name
- NOBLE-TMS (NCT06351514)
- Testing
- Accelerated iTBS
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Institute of Mental Health, Singapore
Schizophrenia, Depression
Neuromodulation in Depressed and Schizophrenic Patients - Changing MEP (Muscle Evoked Potentials) by tDCS (Transcranial Direct Current Stimulation)
Muscle evoked potentials (MEP) are supposed to different in schizophrenic and depressed patients, compared to a sample of healthy volunteers.
- Trial name
- NCT01150734
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Schizophrenia, Negative Type; Schizophrenic
Using Transcranial Magnetic Stimulation (TMS) to Understand 'Negative' Symptoms of Schizophrenia
The main purpose of this study is to learn how transcranial magnetic stimulation (TMS) helps improve negative symptoms of schizophrenia.
- Conditions
- Schizophrenia, Negative Type; Schizophrenic, Schizo Affective Disorder
- Trial name
- NCT03648268
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Beth Israel Deaconess Medical Center
Schizophrenia, Bipolar Disorder
Resting State Electroencephalogram for Psychotic Disorders
Electroencephalography (EEG) has been proposed as a neurophysiological biomarker to delineate psychotic disorders. Meanwhile, the increased appetite, which might related to self-control process, has been an increasing concern for…
- Conditions
- Schizophrenia, Bipolar Disorder, Depression
- Trial name
- NCT05065489
- Testing
- No intervention
- Where
- China
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Central South University
Schizophrenia
Study With Information Technology (IT) - Aided Preventive Program in Schizophrenia
Information Technology-aided Program of Relapse Prevention in Schizophrenia (ITAREPS) will decrease the number of hospitalizations in patients with schizophrenia or schizoaffective disorder who are treated in the outpatient…
- Trial name
- NCT00712660
- Testing
- antipsychotic dose increase, no intervention
- Where
- Czechia
- Volunteers
- 146 people
- Sponsor
- Prague Psychiatric Center
Depression, Loneliness
Empower@Home:Connected - Feasibility and Preliminary Effect Study
This single-group trial will evaluate the feasibility and preliminary effect of a novel group-based cognitive behavioral therapy program for older adults with elevated depressive symptoms.
- Conditions
- Depression, Loneliness, Social Isolation, Depressive Disorder
- Trial name
- NCT05732740
- Testing
- Empower@Home:Connected
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Michigan
Schizophrenia; Psychosis, Nurse's Role
Effect of Applying Cognitive Defusion Techniques on Mindful Awareness, Cognitive Fusion and Believability of Delusions Among Clients With Schizophrenia
Schizophrenia causes hallucinations, delusions, and disorganized thinking, resulting in decreased functioning and lifelong therapy.Delusion believability is the degree of belief in the truth of one's subjective experiences as…
- Conditions
- Schizophrenia; Psychosis, Nurse's Role, Delusions
- Trial name
- NCT05759091
- Testing
- cognitive defusion techniques
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Alexandria University
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