Clinical trials: Psychotic Symptoms
Psychosis
Culturally Adapted Family Intervention For Psychosis
Aim: To assess the feasibility of culturally adapted Family Intervention for Psychosis. Design: Randomized Control Trial Setting: psychiatric department of different hospitals Participants: A total of 36 caregivers of Psychosis…
- Trial name
- NCT02167347
- Testing
- Family intervention
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Pakistan Institute of Living and Learning
Psychosis, Anxiety
Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care
The goal of this pilot randomized controlled trial is to learn if adult patients with acute psychiatric conditions can receive hospital-level care at home. The main question it aims to answer is: 1.
- Conditions
- Psychosis, Anxiety, Depression, Behavioral and Psychiatric Symptoms of Dementia
- Trial name
- BHH (NCT07364825)
- Testing
- Behavioral Health Home Hospital
- Where
- 4 sites in United States
- Volunteers
- 41 people
- Sponsor
- Brigham and Women's Hospital
Schizophrenia, Negative Symptoms
Effective Adjunctive Use of Pergolide for Cognitive Impairment and Negative Symptoms in Schizophrenia
Dopamine has been closely associated with prefrontal function. The hypothesis that a lower dopaminergic activity is associated with negative symptoms and cognitive dysfunction observed in the patients of schizophrenia is of a…
- Conditions
- Schizophrenia, Negative Symptoms, Cognitive Impairments
- Trial name
- NCT00197483
- Testing
- Pergolide (drug)
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Hamamatsu University
Schizophrenia and Related Disorders
Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia
The purpose of this study is to provide an effective repetitive transcranial magnetic stimulation (rTMS) treatment for depressive symptoms in patients with schizophrenia.
- Trial name
- NCT07060066
- Testing
- Active rTMS stimulation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- The University of Texas Health Science Center, Houston
Schizophrenia
Effects of Motivating People With Schizophrenia to Exercise
This study will evaluate the impact of motivational guidance to exercise on people with schizophrenia, based on their participation in a walking program.
- Trial name
- NCT00559572
- Testing
- Motivational group sessions, Time and attention control group sessions
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Tennessee, Knoxville
Women at Risk of Common Mental Disorders
ESM-derived Personalised Feedback for Women at Risk of Common Mental Disorder
This study aims to examine the effectiveness of Experience Sampling Method (ESM) derived personalised feedback for women at risk of common mental disorder in Hong Kong, in reducing individuals depressive and anxiety symptoms.
- Trial name
- NCT04288622
- Testing
- Weekly standardised, personalised feedback
- Where
- Hong Kong
- Volunteers
- 124 people
- Sponsor
- The University of Hong Kong
Schizophrenia, Psychotic Disorders
Augmenting Zyprexa With Naltrexone to Ameliorate Metabolic Side-Effects
The main purpose of this study is to determine whether the opioid antagonist naltrexone is helpful in ameliorating the weight gain and other adverse metabolic side effects experienced by schizophrenic patients taking the second…
- Trial name
- Zyprexa (NCT00567034)
- Testing
- naltrexone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mclean Hospital
Parkinson Disease Psychosis
Hallucinations in Parkinson's Disease
Investigation on how robotically mediated sensorimotor stimulation induces and triggers presence hallucinations in different clinical groups of parkinsonian patients, and in aged-matched controls
- Trial name
- NCT04592965
- Testing
- Clinical and neuropsychological assessments, Induction of PH and associated bodily states, Resting-state fMRI acquisition
- Where
- 6 sites in Spain, Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Olaf Blanke
Bipolar Disorder, Schizoaffective Disorder
Probiotics to Prevent Relapse After Hospitalization for Mania
The purpose of this study is to determine if taking a probiotic supplement versus a placebo will lower rates of relapse and improve the clinical course among participants who have been hospitalized for mania.
- Trial name
- NCT01731171
- Testing
- Probiotic Supplement, Inert Compound
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Sheppard Pratt Health System
Agitation
A Study To Evaluate The Efficacy And Safety Of Intramuscular Levosulpiride In Patients With Agitation Of Schizophrenia
The primary objective of this study is to evaluate the efficacy and safety of Intramuscular Levosulpiride in the treatment of Chinese patients with Agitation Of Schizophrenia compared with Intramuscular Haloperidol by evaluating…
- Trial name
- NCT00866645
- Testing
- Intramuscular Haloperidol, Intramuscular Levosulpiride
- Where
- 5 sites in China
- Volunteers
- 240 people
- Sponsor
- Shanghai Mental Health Center
Schizophrenia, Schizoaffective Disorder
Preventing Relapse in Schizophrenia: Oral Antipsychotics Compared To Injectables: Evaluating Efficacy
This study is designed to find out whether taking antipsychotic medication once every two weeks by injection compared to taking daily oral medication will help people with schizophrenia maintain better control of their symptoms.
- Trial name
- PROACTIVE (NCT00330863)
- Testing
- Risperidone microspheres, Risperidone, Olanzapine
- Where
- 8 sites in United States
- Volunteers
- 357 people
- Sponsor
- Northwell Health
Insomnia, Schizophrenia
Randomized, Controlled, Double Blind Trial of Eszopiclone for Insomnia Associated With Schizophrenia
The major goal of this project is to investigate established insomnia treatments in a schizophrenia population to see if the improved sleep leads to overall better quality of life.
- Conditions
- Insomnia, Schizophrenia, Schizoaffective Disorder, Sleep Disorders
- Trial name
- NCT00645944
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Yale University
Schizophrenia
Repetitive Transcranial Magnetic Stimulation for the Treatment of Negative Symptoms in Schizophrenia Patients.
This study is to determine whether high frequency repetitive transcranial magnetic stimulation (rTMS) is effective in the treatment of negative symptoms in schizophrenia patients
- Trial name
- NCT02842034
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Mental Health Center
Schizophrenia, Depression
Regulation of Arginine-vasopressin (AVP)
This study aims to develop a method for the assessment of central NMDA receptor functioning in patients with depression and schizophrenia.
- Trial name
- REGAVP (NCT02626832)
- Testing
- Procedural
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yale University
Neoplasms, Schizophrenia
EfiKroniK Research Program: Physical Exercise for People With Chronic Pathologies
Clinical objectives: estimate the common effect of the EfiKroniK physical exercise program for people with a set of Chronic diseases (solid cancers, hematological, schizophrenia and COPD), expressed in terms of functional…
- Conditions
- Neoplasms, Schizophrenia, COPD, Physical Activity
- Trial name
- EfiKroniK (NCT03810755)
- Testing
- Personalized Supervised physical activity
- Where
- Spain
- Volunteers
- 370 people
- Sponsor
- Basque Health Service
Schizophrenia, Schizoaffective Disorder
Evaluating the Efficacy of a Late-Life Schizophrenia Integrated Care Pathway to Treat Acute Psychotic Symptoms
As of late Integrated Care Pathways (ICPs) have been shown to improve quality of care in the medical field with special attention given to mental health in particular.
- Trial name
- LLS-ICP (NCT02529163)
- Testing
- Late-life Schizophrenia ICP, Treatment as Usual
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia, Tardive Dyskinesia, Metabolic Syndrome
The Monitor of Serum Prolactin Level in a 3 Months Aripiprazole Trial
A short term post-market monitoring of serum prolactin level change among patients with schizophrenia shifting from other antispychotics to different dosages of aripiprazole.
- Trial name
- NCT00468533
- Testing
- Aripiprazole
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Yu-Li Hospital
Schizophrenia, Therapeutics
Berberine Effects on Clinical Symptoms and Metabolic Disturbance in Patients With Schizophrenia
The study was a 8-week, randomized, double-blind, placebo-controlled trial. Berberine (300 mg，three times a day), as an adjuvant therapy has been used on the basis of the Second-generation antipsychotics（SGAs） monotherapy.
- Trial name
- NCT03548155
- Testing
- Berberine, atypical antipsychotic
- Volunteers
- 65 people
- Sponsor
- Tianjin Anding Hospital
Hypoxia, Mental Disorder
Going to Altitude With Anxious-depressive Symptoms
Introduction: Currently, there is a lack of international guidelines or clinical recommendations for individuals with mental illnesses (i.e., bipolar disorder, posttraumatic stress disorder) going on high altitude sojourns.
- Trial name
- Psychoxie (NCT05323864)
- Testing
- Hypoxia
- Where
- Austria
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universitaet Innsbruck
Serious Mental Illness
Evaluating the Use of Peer Specialists to Deliver Cognitive Behavioral Social Skills Training
The Veterans Health Administration (VHA) is advocating that Veterans with serious mental illness (SMI) receive recovery-oriented, rehabilitation approaches that target real-world functioning.
- Trial name
- CBSST-PEER (NCT03467243)
- Testing
- Cognitive Behavioral Social Skills Training, Social Skills Training, Treatment as usual
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- VA Office of Research and Development
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