Clinical trials: Ptosis
Pelvic Floor Disorders, Urinary Incontinence (UI)
Motivational Interviewing in Women's Pelvic Wellness Education
This pilot study will assess the feasibility and acceptability of an educational workshop on pelvic floor disorders and its potential impact on decisional conflict.
- Conditions
- Pelvic Floor Disorders, Urinary Incontinence (UI), Pelvic Prolapse Conditions
- Trial name
- NCT02758561
- Testing
- Workshop
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Ottawa Hospital Research Institute
Constipation, Surgical Procedure, Unspecified
Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery
The goal of this clinical trial is to test the use of a laxative before surgery in women having surgery to fix pelvic prolapse that do not have constipation.
- Conditions
- Constipation, Surgical Procedure, Unspecified, Prolapse; Female
- Trial name
- NCT06159777
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University Hospitals Cleveland Medical Center
Pelvic Organ Prolapse, Prolapse
PDS Versus Prolene as Suture Material for Vaginal Sacrospinous Hysteropexy
Introduction: Pelvic organ prolapse is a common gynecological disease, which about 50% of women develop in the course of their lives. There are many different options for surgical care, e.g.
- Trial name
- NCT05964881
- Testing
- sacrospinous hysteropexy
- Where
- Austria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Postoperative Pain, Opioid Use
STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery Trial
Overprescribing opioids is considered a major contributor to the opioid crisis. Hill et al. demonstrated that within a general surgery practice, over 70% of the prescribed opioid pills were never taken.
- Conditions
- Postoperative Pain, Opioid Use, Prolapse; Female, Incontinence
- Trial name
- STOP-PAIN (NCT04491617)
- Testing
- Standard opioid prescribing, Restrictive opioid prescribing
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse
A Large Multi-Center Database of Women Who Have Had and Are Going to Have Surgical Correction of Their Pelvic Organ Prolapse Using the Gynecare Prolift System
retrospective and prospective data collection for a database. Patients will have had or are going to have a repair of their pelvic organ prolapse using the Gynecare mesh Prolift System
- Trial name
- NCT01134003
- Where
- United States
- Sponsor
- The Institute of Pelvic Medicine & Reconstructive Surgery, Allentown, Pennsylvania
Glaucoma Eye, Glaucoma
Comparison of Fixation Suture Type in Glaucoma Surgery
The aim of the study is to compare the effectiveness and safety of two types of intraoperative eye fixation: for the superior rectus muscle and traction suture in the peripheral cornea.
- Trial name
- NCT03797846
- Testing
- combined glaucoma surgery
- Where
- Poland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Pelvic Organ Prolapse, Stress Urinary Incontinence
Pessary Experience Study
Pessaries are silicone devices inserted into the vagina for treatment of pelvic organ prolapse or stress urinary incontinence. They are adequate treatment options for patients who are poor surgical candidates, those who decline…
- Trial name
- NCT06021769
- Testing
- Observational only
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Pelvic Organ Prolapse
POPQ Versus Simulated Apical Support as a Guideline for Anterior or Posterior Repair During Vaginal Reconstruction
The objective of the Preoperative Pelvic Organ Prolapse Quantification (POPQ) versus Simulated Apical Support as a Guideline for Anterior or Posterior Repair at the Time of Transvaginal Apical Suspension (PREPARE) trial is to…
- Trial name
- NCT03187054
- Testing
- anterior or posterior colporrhaphy
- Where
- South Korea
- Volunteers
- 335 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain, Pelvic Organ Prolapse
The Effect of Local Analgesia on Postoperative Gluteal Pain in Patients Undergoing Sacrospinous Ligament Fixation
This study will randomize patients to either receive intraoperative administration of local anesthetic and corticosteriod at time of sacrospinous ligament fixation compared to placebo to determine if intraoperative trigger point…
- Conditions
- Postoperative Pain, Pelvic Organ Prolapse, Trigger Point Injection, Sacrospinous Ligament Fixation
- Trial name
- NCT03995641
- Testing
- marcaine and kenalog
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kettering Health Network
Mitral Valve Regurgitation, Mitral Valve Prolapse
Safety and Early Feasibility Study of the Harpoon Medical Device (EFS)
The purpose of this study is to evaluate the safety and performance of the Harpoon Medical TSD-5. The Harpoon device will provide many significant advantages over current surgical interventions including: 1) a small minimally…
- Conditions
- Mitral Valve Regurgitation, Mitral Valve Prolapse, Mitral Valve Insufficiency
- Trial name
- EFS (NCT02771275)
- Testing
- Harpoon Medical Device
- Where
- 2 sites in Poland
- Volunteers
- 13 people
- Sponsor
- Edwards Lifesciences
Mitral Valve Prolapse, Myxomatous Mitral Valve Degeneration
AI-Based Shape and Function Analysis of Mitral Valve Prolapse Using 3D Ultrasound
This study aims to develop and validate a fully automated imaging and modeling pipeline for the analysis of mitral valve prolapse (MVP) using real-time three-dimensional transesophageal echocardiography (RT3DE).
- Trial name
- AI4MVP (NCT07384871)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS Policlinico S. Donato
Urinary Incontinence, Anal Incontinence
Pelvic Floor Muscle Training During Pregnancy
The project seeks to investigate effectiveness of PFMT during pregnancy.
- Conditions
- Urinary Incontinence, Anal Incontinence, Pelvic Organ Prolapse, Sexual Dysfunction
- Trial name
- NCT07104292
- Testing
- PFMT, Standard care
- Where
- Denmark
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Pelvic Organ Prolapse, Stress Urinary Incontinence
Impact of Decision Aids in Urogynecology
To evaluate how patient knowledge and confidence in decision making can be impacted by shared decision making in common urogynecology conditions.
- Conditions
- Pelvic Organ Prolapse, Stress Urinary Incontinence, Overactive Bladder
- Trial name
- NCT04369404
- Testing
- Pelvic organ prolapse decision aid, Stress urinary incontinence decision aid, Overactive bladder decision aid
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Massachusetts General Hospital
Vaginal Cuff Complications
Post-hysterectomy Vaginal Cuff Prolapse Repair
This study is a randomized controlled trial comparing two minimally invasive surgeries-laparoscopic lateral suspension and laparoscopic sacrocolporopexy-for women who develop vaginal cuff prolapse after hysterectomy.
- Trial name
- NCT07174921
- Testing
- Laparoscopic Lateral Suspension, Laparoscopic Sacrocolpopexy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Prolapse
Rehabilitation After Lumbar Disc Surgery: Exercise Therapy and Brief Educational Intervention
Rehabilitation after lumbar disc surgery (prolapse) focuses on various elements such as endurance, strength, stretching and information.
- Trial name
- NCT01779544
- Testing
- Brief intervention, an educational model, Exercise therapy
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Haukeland University Hospital
Vaginal Prolapse
Treatment Outcomes of Vaginal Prolapse Repair
Chart review conducted on all patients having had Prolift surgery since 2005 by Dr. Lary Sirls, Dr. Predeep Nagaraju and Dr. Kenneth Peters at William Beaumont Hospital.
- Trial name
- NCT00679276
- Testing
- Prolift
- Volunteers
- 291 people
- Sponsor
- Corewell Health East
Concomitant Conditions
Factors Affecting the Improvement of Severity of Concomitant USI After a Novel TVM Surgery for Women With POP
Background/Purpose: A novel transvaginal mesh (TVM) surgery for women with pelvic organ prolapse (POP) had been reported. However, factors affecting the efficacy of this novel TVM surgery are unknown; and the above information…
- Trial name
- NCT03607968
- Testing
- The novel anterior TVM surgeries
- Volunteers
- 134 people
- Sponsor
- National Taiwan University Hospital
Sexuality, Pelvic Organ Prolapse
Psychometric Validation of a French Version of the PISQ-R and a New Questionnaire About Sexuality
The primary objective of this study is the psychometric validation of two questionnaires (PISQ-R and a new questionnaire on sexuality) as compared to a non specific questionnaire on female sexual function (FSFI).
- Conditions
- Sexuality, Pelvic Organ Prolapse, Urinary Incontinence, Fecal Incontinence
- Trial name
- NCT01632839
- Where
- 14 sites in France
- Volunteers
- 298 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pelvic Organ Prolapse
Uterosacral Ligament Suspension vs Robotic Sacrocolpopexy
This cross sectional, two cohort study seeks to investigate both anatomic outcome and subjective, functional outcome of uterosacral ligament suspension versus robotic sacrocolpopexy and compare patient satisfaction, bladder…
- Trial name
- NCT02741830
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- TriHealth Inc.
Internal Hemorrhoid, Rectal Prolapse
Cap-assisted Endoscopic Sclerotherapy for Internal Hemorrhoids and Rectal Prolapse
This clinical trial aims to evaluate the efficacy and safety of long needle and short needle in the treatment of internal hemorrhoids and rectal prolapse through CAES (Cap-assisted endoscopic sclerotherapy).
- Trial name
- NCT03917056
- Testing
- Cap-assisted endoscopic sclerotherapy using long needle, Cap-assisted endoscopic sclerotherapy using short needle
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The Second Hospital of Nanjing Medical University