Clinical trials: Public Speaking
Fear of Public Speaking (Subclinical)
Investigation of the Efficacy of a VR Exposure-based Eye Contact Training to Reduce Fear of Public Speaking
Investigation of the efficacy of an eye contact training App in virtual reality, based on principles of exposure therapy for the treatment for subjects with fear of public speaking.
- Trial name
- ASSIST-2019 (NCT03970187)
- Testing
- Exposure-based eye contact training in Virtual Reality (VR)
- Where
- Switzerland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Performance Anxiety
Predictors of Exposure Success in Public Speaking Anxiety
Anxiety disorders are common and impairing. Although exposure therapy is one of the most effective treatments for anxiety, some individuals do not fully respond to treatment, and these individual differences are not well…
- Trial name
- NCT02163148
- Testing
- Massed speech exposure session
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego
Public Speaking, Social Anxiety
Virtual Reality Exposure Therapy for Public Speaking Anxiety
Virtual Reality exposure therapy (VRET) is an efficacious treatment for anxiety disorders but has yet to be implemented in regular care settings.
- Conditions
- Public Speaking, Social Anxiety, Social Anxiety Disorder, Performance Only
- Trial name
- VRETA (NCT03885414)
- Testing
- In-session Virtual Reality exposure therapy, Internet-administered transition program
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Public Speaking Fear
ACT and Virtual Reality for Public Speaking Fear
Investigation of Acceptance and Commitment Therapy (ACT) for the psychological treatment of public speaking fear. Two ACT-based treatment delivery modalities (in vivo exposure vs. virtual reality) were compared.
- Trial name
- NCT05573620
- Testing
- ACT, In vivo exposure:, Virtual Reality
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- Universidad Europea de Madrid
Public Speaking Fear
Optimizing Exposure Therapy Via Reward-focused Interventions in Individuals With Public Speaking Anxiety
The present study aims to examine whether the efficacy of an exposure treatment in individuals with public speaking anxiety can be enhanced by implementing interventions that target reward processes.
- Trial name
- EXOPAT (NCT06258889)
- Testing
- reward-focused intervention, cognitive flexibility intervention, exposure
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Public Speaking Anxiety
Virtual Reality Exposure for Public Speaking Anxiety
This study aims to examine the efficacy of exposure using virtual reality (VR) for public speaking anxiety in young adults in two treatment arms: a one-session VR exposure therapy with a 4-week online transition intervention…
- Trial name
- VRanx (NCT06214039)
- Testing
- Exposure in virtual reality and text based cognitive behavioral therapy (CBT) for public speaking anxiety
- Where
- Lithuania
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Social Anxiety Disorder
A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder
This U.S. multicenter, double-blind, placebo-controlled Phase 2 clinical trial is designed to evaluate the efficacy, safety, and tolerability of a repeat intranasal (i.n.) dose of Fasedienol Nasal Spray (fasedienol) (3.2 µg) to…
- Trial name
- NCT06809179
- Testing
- Fasedienol Nasal Spray - Fasedienol Nasal Spray
- Where
- 9 sites in United States
- Volunteers
- 60 people
- Sponsor
- VistaGen Therapeutics, Inc.
Anxiety Disorders
Medication Enhanced Rapid Therapy
The purpose of this research study is to determine whether taking a one-time dose of a combination of putatively learning-enhancing medications can improve treatment response to a brief learning-based psychotherapy for public…
- Trial name
- MERiT (NCT02099825)
- Testing
- d-cycloserine and mifepristone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Social Anxiety Disorder (SAD)
Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-4)
This U.S. Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute intranasal (i.n.) administration of Fasedienol Nasal Spray (fasedienol) (3.2 µg) to relieve symptoms of acute anxiety in…
- Trial name
- PALISADE-4 (NCT06615557)
- Testing
- Fasedienol Nasal Spray
- Where
- 26 sites in United States
- Volunteers
- 238 people
- Sponsor
- VistaGen Therapeutics, Inc.
Depressive Disorder and Anxiety Disorders
PET (Positron Emission Tomography)/Public Speaking Study With A Combination Of 2 Medications In Social Anxiety Patients
This six-arm study is being conducted to measure the effect of a combination of paroxetine and vestipitant on the arousal induced by public speaking in Seasonal Effective Disorder (SAD) patients, using functional brain imaging…
- Trial name
- NCT00343707
- Testing
- vestipitant, paroxetine
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- GlaxoSmithKline
Public Speaking, Speech Anxiety
Virtual Reality Intervention for Speech Anxiety
Exposure-based cognitive behavior therapy is an efficacious treatment for speech anxiety and has been delivered effectively in a virtual reality (VR) environment.
- Trial name
- NCT06086756
- Testing
- Exposure intervention plus positive mood induction, Exposure intervention plus negative mood induction
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Social Anxiety Disorder
PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge - 2
This Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute administration of 3.2 µg of PH94B to relieve symptoms of anxiety in adult subjects with social anxiety disorder (SAD) during…
- Trial name
- Palisade-2 (NCT05011396)
- Testing
- PH94B Nasal Spray
- Where
- 15 sites in United States
- Volunteers
- 228 people
- Sponsor
- VistaGen Therapeutics, Inc.
Oral Cavity Squamous Cell Carcinoma
Biofeedback Rehabilitation to Improve Speaking and Eating in Public
Tongue cancer requires resection and reconstruction that can leave patients disabled with respect to speaking and eating. Impairment of tongue function can have significant impact on social interaction and employment.
- Trial name
- Biofeedback (NCT03650699)
- Testing
- Electropalatography Biofeedback Training
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University Health Network, Toronto
Phobic Disorders, Social Phobia
Treatment of Social Phobia
Social phobia is a very common and debilitating disorder, with public speaking anxiety being the most common fear. Psychologists have found that treating patients for their fear of public speaking, through cognitive-behavioral…
- Conditions
- Phobic Disorders, Social Phobia, Public Speaking Anxiety
- Trial name
- NCT00000370
- Testing
- Cognitive behavior therapy, Performance-based exposure therapy, Psychosocial intervention
- Where
- United States
- Sponsor
- Boston University Charles River Campus
Obesity, Insulin Resistance
Systemic Cross-talk Between Brain, Gut, and Peripheral Tissues in Glucose Homeostasis: Effects of Exercise Training
Obesity and insulin resistance are worldwide epidemic and taking a major public health toll. Obesity also increases the risk for cognitive impairment which is also an increasing medical, societal, and economic challenge.
- Conditions
- Obesity, Insulin Resistance, Type2 Diabetes, Exercise Training
- Trial name
- CROSSYS (NCT03730610)
- Testing
- Exercise training
- Where
- Finland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Turku
Social Anxiety Disorder
Brief Intervention to Reduce Fear of Public Speaking
The study will test the efficacy of propranolol or placebo, administered after retrieval of a previously acquired public speaking fear, in reducing fear and avoidance of public speaking.
- Trial name
- NCT02790736
- Testing
- propranolol
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- New York State Psychiatric Institute
Anxiety, Social
An Online Large-group One-session Treatment for Public Speaking Anxiety
Different conceptualizations of public speaking anxiety exist to which it can be either considered as a qualitatively distinct subtype of social phobia or a quantitatively less severe form of a more impairing generalized social…
- Trial name
- NCT04790864
- Testing
- Online large-group one-session treatment with post-treatment exercise targeting expectancy violation, Online large-group one-session treatment with post-treatment control exercise
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Ruhr University of Bochum
Smoking Cessation
Spanish-Language Smoking Cessation Trial
Results of a recently completed National Cancer Institute (NCI) funded trial of an intervention, Forever Free: Stop Smoking for Good, revealed high efficacy throughout the 24- month follow-up period, further supporting the…
- Trial name
- NCT02945787
- Testing
- Spanish-Language Version of the Stop Smoking for Good, NCI-Produced Spanish-language Self-help Booklet
- Where
- United States
- Volunteers
- 1,417 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Social Anxiety Disorder (Social Phobia), Public Speaking Anxiety
Reward Processing and Exposure Therapy for Social Anxiety Disorder
The investigators are conducting a clinical trial of therapy for public speaking anxiety. There are many eligibility criteria, but the main ones are that participants need to be socially anxious and have public speaking anxiety.
- Conditions
- Social Anxiety Disorder (Social Phobia), Public Speaking Anxiety, Anhedonia, ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
- Trial name
- METER (NCT06776991)
- Testing
- Positive Affect Treatment - Behavioral (PAT-B), Relaxation Treatment, Exposure Therapy
- Where
- 2 sites in United States
- Volunteers
- 94 people
- Sponsor
- University of California, Los Angeles
Public Speaking Anxiety
Online Psychotherapy for Emotional Reasoning Bias in Public Speaking Anxiety
The study aims to develop and implement a self-applied online psychological intervention for the correction of Emotional Reasoning bias for people with public speaking anxiety.
- Trial name
- NCT06552273
- Testing
- Emotional Reasoning bias correction training, Module of Mindfulness of the Transdiagnostic treatment
- Volunteers
- 158 people
- Sponsor
- Universitat Jaume I