Clinical trials: Puerperal Depression
Postpartum Depression
Mothers Avoiding Depression Through Empowerment Intervention Trial
Postpartum depressive symptoms are a major health problem that affects hundreds of women annually. The investgators propose to test an intervention to reduce postpartum depressive symptoms and prevent elevated levels of…
- Trial name
- MADE IT (NCT01312883)
- Testing
- Behavioral education intervention
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Depression
Functional Outcome in Postpartum Depression in Women Treated With Desvenlafaxine
Postpartum depressed women suffer from functional impairment in their mood, thoughts, cognition and physical well being leading to poor motivation, bonding difficulties, decreased productivity, conflict and neglect.
- Trial name
- NCT01527786
- Testing
- Desvenlafaxine
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- BC Women's Hospital & Health Centre
Depression, Posttraumatic Stress Disorder
Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa
Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in preventing HIV.
- Conditions
- Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
- Trial name
- NCT05624931
- Testing
- Brief CBT-Based Intervention, Enhanced Treatment as Usual
- Where
- 2 sites in United States, South Africa
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Post Partum Depression
Risk of Maternal Depression From 1 Year to 4 Years Postpartum in Yvelines
This observational study aims to estimate the prevalence of women from 1 to 4 years postpartum in Yvelines, who are suspected to suffer from postpartum depression, using the Edinburg Post natal Depression Scale (EPDS) and the…
- Trial name
- DeTaPoP (NCT06042972)
- Testing
- Questionnaire including Edinburgh postnatal depression scale, Patient Health Questionnaire 2 and background variables
- Where
- France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Centre Médical Porte Verte
Depression
Preventing Postpartum Depression in African American Home Visiting Clients
The goal of this study is to determine whether a 6 week intervention is effective in preventing the worsening of depressive symptoms and development of clinical depression in low-income African American pregnant and recently…
- Trial name
- NCT01175603
- Testing
- Mothers and Babies Course (Adapted for Baltimore Home Visiting Programs)
- Where
- 4 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Experience, Life, Stress
The Use of the Diary in Neonatal Pathology: a Mixed-method Study for Collecting and Analyzing the Experience of Parents and Health Care Personnel.
The study is mixed-methods (qualitative + quantitative observational cross-sectional) and the aims are to explore the use of diaries by parents of newborns admitted to Neonatal Pathology and to describe some variables related to…
- Conditions
- Experience, Life, Stress, Depression, Postpartum, Support, Family
- Trial name
- DiaPaNeo (NCT06316193)
- Testing
- Diary
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Parturients, Depressive Symptoms
Intranasal Esketamine-dexmedetomidine Combination and Postpartum Depression
Esketamine has rapid-onset antidepressant effects and may reduce postpartum depression in parturients with prenatal depressive symptoms. However, its adverse neuropsychiatric symptoms limits clinical application.
- Conditions
- Parturients, Depressive Symptoms, Esketamine, Dexmedetomidine
- Trial name
- NCT07639099
- Testing
- Esketamine-dexmedetomidine combination
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Peking University First Hospital
Postpartum Depression (PPD), Perinatal Anxiety
Midwife-led Childbirth Review and Psychological Outcomes in New Parents
The aim of this clinical trial is to support psychological well-being and facilitate adjustment to parenthood among postpartum mothers and fathers through a midwife-led childbirth review (MLCR).
- Conditions
- Postpartum Depression (PPD), Perinatal Anxiety, Postpartum Mental Health
- Trial name
- CROWN (NCT07678801)
- Testing
- Midwife-led childbirth review (MLCR)
- Where
- 2 sites in Czechia
- Volunteers
- 1,300 people
- Sponsor
- Charles University, Czech Republic
Depressive Symptoms, Anxiety Disorders and Symptoms
Pregnancy Without Psychosocial Stress
The project is aimed at children who are exposed to the toxic psychosocial stress present in their mothers during pregnancy or after childbirth.
- Conditions
- Depressive Symptoms, Anxiety Disorders and Symptoms, Depression, Postpartum
- Trial name
- NCT04853693
- Testing
- Mom´s Supporting Mom, Enhanced Treatment As Usual
- Where
- Czechia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health, Czech Republic
Postnatal Depression, Mother-Infant Interaction
A Virtual Support Intervention for Postnatal Well-being
Postnatal depression (PND) and anxiety are significant public health concerns affecting a substantial proportion of new mothers worldwide.
- Trial name
- NCT06557200
- Testing
- Digital Infant- parents support
- Where
- Pakistan
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Ultrasonography Prenatal
The Effect of Visual and Audio Stimulus Offered to Father-to-be
It was aimed to evaluate the effect of visual and auditory stimuli presented to father candidates on postpartum breastfeeding success of mothers, perception of spousal support and postpartum depression.
- Trial name
- NCT06282419
- Testing
- USE OF MOBILE ULTRASOUND, ultrasound image taken from the internet
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Depression During Pregnancy
The Association Between Gut Microbiota Diversity and Postpartum Depression
This study aims to examine whether naturally occurring bacteria in the gastrointestinal tract are associated with mood changes following childbirth, including postpartum depression.
- Trial name
- NCT07227753
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Postpartum Depression (PPD)
Moringa Oleifera and Phoenix Dactylifera L. Effects on Cortisol and Breast Milk in Postpartum Depression
Postpartum depression affects 10-20% of new mothers globally, potentially disrupting breast milk production. This study aimed to provide valuable insights into effective interventions to improve the health and well-being of…
- Trial name
- NCT07337512
- Testing
- Phoenix dactylifera L, Moringa oleifera
- Where
- Indonesia
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Melania Asi
Postpartum Period, Depression
Relationship Between Postpartum Mood Disorders and Delivery Experience
The purpose of this study is to evaluate potential risk factors for developing postpartum depression or posttraumatic stress disorder during the first year postpartum in patients who have no preexisting history of PTSD or PPD.
- Conditions
- Postpartum Period, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NCT03004872
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Michigan
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Postpartum Depression, Postnatal Depression
Phase 2 Clinical Trial of GH001 in Postpartum Depression
This study is a multicenter, open-label, single-arm Phase 2 clinical trial. Approximately 15 female participants with clinically diagnosed postpartum depression (PPD) will be included in this study.
- Trial name
- NCT05804708
- Testing
- GH001
- Where
- 4 sites in Netherlands, United Kingdom
- Volunteers
- 10 people
- Sponsor
- GH Research Ireland Limited
Postpartum Depression
Lexapro in the Treatment of Patients With Postpartum Depression
The purpose of this study is to determine if Escitalopram (Lexapro) is effective in the treatment of postpartum depression.
- Trial name
- NCT00277108
- Testing
- Escitalopram (Lexapro)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Rochester
Depression, Postpartum
The Northern Babies Longitudinal Study
Postpartum depression (PPD) is a prevalent disorder. Studying the factors related to PPD will help to identify families at risk and provide preventive interventions.
- Trial name
- NCT02538497
- Testing
- The Newborn Behavioral Observation (NBO), Routine care
- Where
- Norway
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Postpartum Depression
The Effects of Motherly on Postpartum Depression
Investigators will be test the efficacy of Motherly, a smartphone application (app) to treat depression in women with postpartum Depression.
- Trial name
- NCT05055674
- Testing
- Motherly app, COMVC app
- Volunteers
- 264 people
- Sponsor
- University of Sao Paulo
Post Partum Depression
Sensing Technologies for Maternal Depression Treatment in Low-Resource Settings
In certain low- and middle- income country settings, there is a disproportionate level of untreated postpartum depression that presents both acute and long-term risks to a mother's well-being.
- Trial name
- StandStrong (NCT06253676)
- Testing
- Problem Management Plus (PM+)
- Where
- Nepal
- Volunteers
- 121 people
- Sponsor
- George Washington University