Clinical trials: Puerperal Depression
Depression, Depression, Postpartum
Randomized Controlled Trial of the Alma Peer Mentoring Program for Pregnant Women Experiencing Depression
Women have double the odds of getting depressed as men and commonly experience depression during the childbearing and early parenting years. Many new and expectant mothers who experience depression never receive help.
- Trial name
- NCT02883686
- Testing
- Alma
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- University of Colorado, Boulder
Depression, Postpartum, Stress, Psychological
MAMA NO STRESS Project. The Effects of the "HAPPY MAMA" Intervention
This study evaluates the effects of a postpartum intervention in increasing the maternal well-being and self-efficacy of Italian women in the first one to six months after childbirth, as well as in reducing postpartum depression…
- Conditions
- Depression, Postpartum, Stress, Psychological, Postpartum Sadness, Self Efficacy
- Trial name
- NCT04093791
- Testing
- Collective Intervention "G", Individual Intervention "I"
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Contraception, Postpartum Depression
Timing of Postpartum Depot Medroxyprogesterone Acetate Administration on Breastfeeding, Contraceptive Continuation, and Depression
The investigators plan to enroll 184 women who are planning to breastfeed and use DMPA after delivery to find out whether the timing of postpartum administration of DMPA (prior to hospital discharge or 4-6 weeks after delivery)…
- Conditions
- Contraception, Postpartum Depression, Lactation
- Trial name
- DEPO-ABCD (NCT01463202)
- Testing
- Depot medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Beatrice Chen
Depression, Postpartum
A Study to Learn More About How Zuranolone Affects Postpartum Depression Symptoms in Participants Who Took it Within 1 Year After The End of Their Pregnancy
In this study, researchers will learn more about how zuranolone affects the symptoms of postpartum depression, also known as PPD. Zuranolone is a drug that healthcare professionals can prescribe for adults with PPD.
- Trial name
- NCT07047820
- Testing
- Zuranolone
- Where
- United States
- Volunteers
- 305 people
- Sponsor
- Biogen
Bariatric Surgery Status in Childbirth, Puerperal Depression
Survey on Patients After Childbearth Following Bariatric Surgery
Women with a history of bariatric surgery may face various difficulties during pregnancy and puerperal time. Therefore it is assumed the prevalence of mental health disorders might be higher than in average women during and after…
- Trial name
- SPOtMom (NCT04297956)
- Where
- 5 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Wuerzburg University Hospital
Depression, Unipolar, Pain, Postoperative
Maternal Mindfulness: Depression and Postpartum Pain
This phase I clinical trial tests the feasibility and safety of a self-guided, mobile mindfulness-based intervention to reduce post-cesarean pain and prevent postpartum depression.
- Trial name
- MaMiDaPP (NCT05400382)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Postpartum Women
Comparison of the Effects of Aerobic Exercise and Connective Tissue Massage in Postpartum Women
The aim of this study is to compare the effects of aerobic exercise and connective tissue massage on sleep, mother-infant attachment and psychological state in postpartum women.
- Trial name
- NCT05721625
- Testing
- Aerobic exercise, Connective tissue massage
- Volunteers
- 40 people
- Sponsor
- Ankara Yildirim Beyazıt University
Postpartum Depression, Sleep Disorder
The Effects of Pregnancy Classes and Contributing Factors to Postpartum Depression
It is recommended by the American College of Obstetricians and Gynecologists' Committee on Obstetric Practice that all obstetricians screen each women for postpartum depression and anxiety with a validated instrument.
- Conditions
- Postpartum Depression, Sleep Disorder, Breast Feeding, Self Esteem
- Trial name
- NCT03763435
- Testing
- Antenatal pregnancy classes
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Bartin State Hospital
Depression, Postpartum, Depression
Depression Prevention for Pregnant Women on Public Assistance
This study will evaluate the effectiveness of an interpersonal therapy treatment called the Postpartum Prevention Program in preventing the development of postpartum depression in pregnant women who are financially disadvantaged.
- Trial name
- NCT00601757
- Testing
- The Postpartum Prevention Program (PPP), Enhanced care as usual (ECU)
- Where
- 3 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Depressive Disorder, Depression
A Clinical Trial of Oral Ganaxolone in Women With Postpartum Depression
A clinical study to evaluate safety, tolerability and efficacy of oral administration of ganaxolone in women with postpartum depression
- Conditions
- Depressive Disorder, Depression, Depression, Postpartum, Behavioral Symptoms
- Trial name
- NCT03460756
- Testing
- Ganaxolone
- Where
- 33 sites in United States
- Volunteers
- 84 people
- Sponsor
- Marinus Pharmaceuticals
Depression During Pregnancy
The Association Between Gut Microbiota Diversity and Postpartum Depression
This study aims to examine whether naturally occurring bacteria in the gastrointestinal tract are associated with mood changes following childbirth, including postpartum depression.
- Trial name
- NCT07227753
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Parturition, Analgesia, Obstetrical
Neuraxial Labor Analgesia and the Incidence of Postpartum Depression
Postpartum depression (PPD) affects approximately 15% of women during the first year after giving birth, and is common across cultures. The etiology of postpartum depression is not totally clear.
- Conditions
- Parturition, Analgesia, Obstetrical, Depression, Postpartum
- Trial name
- NCT02823418
- Testing
- No neuraxial labor analgesia, Neuraxial labor analgesia
- Volunteers
- 599 people
- Sponsor
- Peking University First Hospital
Postpartum Depression, Progressive Muscle Relaxation
Postpartum Depression and Maternal Attachment
In terms of postpartum care and depression, follow-up and controls should be continued online in order not to interrupt the follow-up and treatment of women.
- Trial name
- NCT05038085
- Testing
- progressive muscle relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gazi University
Depression, Postpartum
Type II Diabetes Mellitus in Patients Exposed to Pravastatin and Paroxetine
Type 2 Diabetes (T2DM) is a life-long, chronic condition affecting an individuals' ability to regulate glucose levels in the blood. Diabetes can cause many severe complications if not treated properly.
- Trial name
- NCT01602913
- Testing
- Pravastatin alone, Paroxetine alone, Pravastatin and paroxetine combined
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Preterm Birth, Postpartum Depression
COntact RElationship in Neonatal Intensive Care Unit
The present research project aims to explore the value that contact relationships between caregivers and the preterm infant may have in terms of promoting developmental and maturational processes,by attending to the…
- Trial name
- CORE in NICU (NCT06462638)
- Testing
- Neurobehavioral states and physiological parameters evaluation, Maternal vocal pitch evaluation to assess depressive/anxious state
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Postpartum Depressive Disorder
Quetiapine in Postpartum Depression
The purpose of the study is to evaluate the efficacy and tolerability of quetiapine in female patients with postpartum depressive disorder with psychotic symptoms
- Trial name
- NCT00681668
- Testing
- Quetiapine
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- AstraZeneca
Postpartum Depression, Insomnia
Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health
Improving maternal mental health is a worldwide health priority. Nevertheless, several scientific sources highlighted lack of empirical data which could drive clinical practice.
- Conditions
- Postpartum Depression, Insomnia, Stress
- Trial name
- MOTHERS (NCT06379074)
- Testing
- Improving sleep health and resilience during pregnancy, Information on pregnancy-related issues
- Where
- 2 sites in Italy
- Volunteers
- 114 people
- Sponsor
- University of Rome G. Marconi
Postpartum Depression, Posttraumatic Stress Disorder
Intervention for IPV-exposed Pregnant Women
The overarching goal of the proposed project is to evaluate a randomized clinical trial of the Pregnant Moms' Empowerment Program aimed at detecting its effects on maternal mental health, re-victimization, parenting sensitivity…
- Conditions
- Postpartum Depression, Posttraumatic Stress Disorder, Infant Behavior, Violence
- Trial name
- NCT04068662
- Testing
- Pregnant Moms' Empowerment Program, Nondirective Support Group
- Where
- 2 sites in United States
- Volunteers
- 424 people
- Sponsor
- University of Notre Dame
Infant Colic, Postpartum Depression
Measuring and Reducing Excessive Infant Crying
Excessive infant crying (EIC) is likely to increase the risk of child abuse. The investigators propose a randomized trial using an intervention based on recommendations of Karp.
- Trial name
- UTHealth THB (NCT01217658)
- Testing
- The Happiest Baby on The Block, AAP Infant Colic counseling
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The University of Texas Health Science Center, Houston
Post-partum Depression
Preventing Postpartum Depression in Prenatal Care
This is randomized control trial of a brief intervention called Bellevue ROSE (Reach Out Stay Strong Essentials). Bellevue ROSE is a manualized and highly structured interpersonal intervention that provides women with…
- Trial name
- NCT02741206
- Testing
- Bellevue ROSE Intervention, Psycho-education session and usual, Standard of care Control, One Psycho-education session and usual, standard of care Control
- Where
- United States
- Sponsor
- NYU Langone Health