Clinical trials: Puerperal Depression
Overweight and Obesity, Depression, Postpartum
Madres Para la Salud (Mothers for Health)
The purpose of "Madres Para la Salud" [Mothers for Their Health] is to see how support and encouragement can help women to make positive changes in their health.
- Conditions
- Overweight and Obesity, Depression, Postpartum, Mother (Person)
- Trial name
- NCT01908959
- Testing
- Madres para la Salud
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Postpartum Depression
Aripiprazole and Resistant Postpartum Depression
Currently there are no controlled data on the management of postpartum depression that fails to respond to adequate antidepressant therapy.
- Trial name
- NCT01386086
- Testing
- aripiprazole
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Depression, Postpartum, Anxiety Disorders
Inhaled Oxytocin and HPA Axis Reactivity
Mothers who were enrolled in the Mood, Mother and Infant study will be eligible to participate in the 6-year follow-up maternal visit.
- Conditions
- Depression, Postpartum, Anxiety Disorders, Stress, Psychological
- Trial name
- NCT03593473
- Testing
- Intranasal Oxytocin
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of North Carolina, Chapel Hill
Postpartum Depression, Maternal Self-Efficacy
The Effect of Psychodramatic Role-Playing on Postpartum Depression, Self-Efficacy, and Perceived Social Support
This research was conducted to examine the effect of psychodramatic role-playing in childbirth preparation courses on postpartum depression, self-efficacy, and perception of social support.
- Conditions
- Postpartum Depression, Maternal Self-Efficacy, Perceived Social Support, Pregnancy
- Trial name
- NCT07506759
- Testing
- Psychodramatic Role-Playing Childbirth Education, Standard Childbirth Education
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Postpartum Depression (PPD)
Moringa Oleifera and Phoenix Dactylifera L. Effects on Cortisol and Breast Milk in Postpartum Depression
Postpartum depression affects 10-20% of new mothers globally, potentially disrupting breast milk production. This study aimed to provide valuable insights into effective interventions to improve the health and well-being of…
- Trial name
- NCT07337512
- Testing
- Phoenix dactylifera L, Moringa oleifera
- Where
- Indonesia
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Melania Asi
Postnatal Depression, Mother-Infant Interaction
A Virtual Support Intervention for Postnatal Well-being
Postnatal depression (PND) and anxiety are significant public health concerns affecting a substantial proportion of new mothers worldwide.
- Trial name
- NCT06557200
- Testing
- Digital Infant- parents support
- Where
- Pakistan
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Postnatal Depression, Genetic Predisposition
Sequence Variations of Genes in the Estrogen Pathway and Perinatal Depression
To elucidate the disease pathway of perinatal depression by identifying genetic variants which could play a role in predisposing to the condition and/or lead to better understanding of the pathogenesis of the condition.
- Trial name
- NCT02373709
- Where
- Singapore
- Volunteers
- 750 people
- Sponsor
- KK Women's and Children's Hospital
Perinatal Depression
PRogram In Support of Moms (PRISM): A Pilot Study
The primary goal of this study is to evaluate the PRogram In Support of Moms (PRISM) that aims to improve women's access to and participation in perinatal depression treatment and thereby improve depression outcomes
- Trial name
- PRISM-Pilot (NCT02935504)
- Testing
- PRogram In Support of Moms (PRISM), MCPAP for Moms
- Volunteers
- 33 people
- Sponsor
- University of Massachusetts, Worcester
Neurodevelopmental Disorders
5-Year Follow-up of Children and Mother After Expectant Management Versus Induction of Labor in Low-risk Nulliparous Women at 39 Weeks of Gestation
In France, the rate of labor induction has markedly increased in recent years, partly following the ARRIVE trial suggesting short-term benefits of elective induction at 39 weeks in low-risk nulliparous women.
- Trial name
- FAMILY-FA (NCT07330336)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 4,200 people
- Sponsor
- University Hospital, Bordeaux
Depression, Clinical Depression
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records
- Conditions
- Depression, Clinical Depression, Depression, Anxiety, Depression, Postpartum
- Trial name
- NCT04211467
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Depression, Postpartum, Efficacy, Self
A Dyadic Approach to Perinatal Depression in Primary Care: Maternal Infant and Dyadic Care
The purpose of this study is to assess the effectiveness of a parenting intervention+usual care compared to usual care on postpartum depression and other mental health and parenting outcomes, as well as the feasibility and…
- Conditions
- Depression, Postpartum, Efficacy, Self, Anxiety
- Trial name
- MInD (NCT04998721)
- Testing
- Promoting First Relationships-Brief, Perinatal Collaborative Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Esketamine, Postpartum Depression
Esketamine on Postpartum Depression in Cesarean Section Women
This study was to explore the preventive effect of esketamine on postpartum depression (PPD) in cesarean section, and to evaluate the safety of the drug
- Trial name
- EKET (NCT04860661)
- Testing
- Esketamine, Normal saline
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Ailin Luo
Health Attitude, Knowledge, Attitudes, Practice
Development and Pilot Test of a Postnatal mHealth Intervention - Phase 2
The goal of the study is to assess the feasibility and acceptability of the optimized MeSSSSage intervention which was developed and revised based on the results of our initial pilot testing.
- Conditions
- Health Attitude, Knowledge, Attitudes, Practice, Post Partum Depression, Acceptability of Health Care
- Trial name
- MESSAGE (NCT04693585)
- Testing
- MESSSSAGE - live, MESSSSAGE - asynchronous
- Where
- India
- Volunteers
- 201 people
- Sponsor
- University of California, San Francisco
Postpartum Depression
A Study to Evaluate Safety and Efficacy of SAGE-547 in Participants With Moderate Postpartum Depression (547-PPD-202C)
The purpose of this study was to determine if SAGE-547 Injection infused intravenously at up to 90 μg/kg/h for 60 hours reduces depressive symptoms in participants with moderate postpartum depression (PPD) compared to placebo…
- Trial name
- NCT02942017
- Testing
- SAGE-547 90 μg/kg/h
- Where
- 32 sites in United States
- Volunteers
- 108 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Postpartum Depression
A Study to Evaluate SAGE-217 in Participants With Severe Postpartum Depression
The primary purpose of this study was to determine if treatment with SAGE-217 reduces depressive symptoms in participants with severe postpartum depression (PPD) compared to placebo as assessed by the change from baseline in the…
- Trial name
- NCT02978326
- Testing
- SAGE-217 15/20 mg Oral Solution, SAGE 217 30 mg Capsules
- Where
- 27 sites in United States
- Volunteers
- 276 people
- Sponsor
- Biogen
Postpartum Depression, Postpartum Disorder
Maternal Well-being in the Postnatal Stage
The objective of this study is to design and validate an online intervention aimed at promoting well-being in women with postpartum depression.
- Trial name
- BIEMAT (NCT05676918)
- Testing
- Positive Psychology Intervention, Cognitive Behavior Therapy
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Universidad Complutense de Madrid
Premature Birth, Pregnancy Preterm
Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study
This is a randomized comparative effectiveness study of two forms of enhanced prenatal care among 674 Medi-Cal eligible pregnant individuals in Fresno, California.
- Conditions
- Premature Birth, Pregnancy Preterm, Prenatal Stress, Depression, Anxiety
- Trial name
- EMBRACE (NCT04154423)
- Testing
- Glow! Group Prenatal Care, Individual Prenatal Care with CPSP
- Where
- 2 sites in United States
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sleep Quality, Depression, Postnatal Care, Single-Blind Method, Fatigue, Social Support
Can Postpartum Depression Be Prevented With Care
This study was designed to eliminate postpartum insomnia and fatigue and reduce the risk of postpartum depression through the maintenance of structural, personal, and social integrity with holistic care under the guidance of…
- Trial name
- NCT05295069
- Testing
- A nursing care program was applied for the intervention group under the guidance of Levine's conservation model.
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Depression, Postpartum
Outcome of Postnatal Depression Screening Using Edinburgh Postnatal Depression Scale
The objective of the present study is to evaluate the effectiveness of postnatal depression screening by comparing the mental health outcome (at 6 months postpartum) of mothers under the Edinburgh Postnatal Depression Scale…
- Trial name
- NCT00251342
- Testing
- Edinburgh Postnatal Depression Scale
- Where
- China
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Postnatal Depression
Community Singing Interventions for Postnatal Depression: a Hybrid Type II Effectiveness-implementation Trial
Postnatal depression (PND) affects over 13% of new mothers but there is still not an ideal treatment for all cases. Pharmaceutical and psychotherapy have offered solutions but there are challenges in treatment uptake and…
- Trial name
- SHAPER-PND (NCT04834622)
- Testing
- Melodies for Mums, Control Community Sessions
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- King's College London