Clinical trials: Puerperal Depression
Postpartum Depression (PPD)
SAINT in Postpartum Depression (PPD)
This study is a large, multi-site clinical trial testing whether Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT), a fast-acting form of repetitive transcranial magnetic stimulation (rTMS), can more effectively…
- Trial name
- NCT07210255
- Testing
- SAINT Neuromodulation System
- Where
- 4 sites in United States
- Volunteers
- 192 people
- Sponsor
- Magnus Medical
Postpartum Depression
Peer Administered Online CBT for PPD
Postpartum depression (PPD) affects up to one in five of women and has profound effects on mothers and their infants. Unfortunately, fewer than 15% of women with PPD receive evidence-based care.
- Trial name
- PL-OCBT (NCT04913584)
- Testing
- Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- McMaster University
Perinatal Depression, Postpartum Depression
Integrating Text Messages Into the Mothers and Babies Course
This project is aimed at enhancing the effectiveness and scalability of the Mothers and Babies 1-on-1 Course (MB) among home visiting programs.
- Trial name
- NCT03420755
- Testing
- Mothers and Babies 1-on-1, Mothers and Babies Plus Text
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postpartum Depression
Dynamic Neural Mechanisms of Brexanolone-induced Antidepressant Effects in Postpartum Depression
This is a feasibility study of performing repeated EEG recordings and assessment of affective states during open-label administration of BRX to women with postpartum depression.
- Trial name
- BRX-PPD (NCT05543746)
- Testing
- Brexanolone
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pregnancy, Mother
A Feasibility Study of AMOR; ADHD, Mothers Online Resources
The primary aim of this study is to investigate the feasibility of the program AMOR for pregnant women and new mothers with Attention Deficit Hyperactivity Disorder (ADHD), by examining adherence, credibility, treatment…
- Conditions
- Pregnancy, Mother, Women, Attention Deficit Disorder With Hyperactivity
- Trial name
- AMOR (NCT06679010)
- Testing
- Online group counseling
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- University of Southern Denmark
Post Partum Depression, Quality of Life
Impact of Mothers Touch Program to Improve Maternal Health After Birth
After the child birth most women experience major health issues such as depression, severe fatigue, back pain, perineal pain, mastitis, urinary or faecal incontinence, sexual problems and relationship problems with partners.
- Trial name
- NCT03715218
- Testing
- Mothers Touch Program, Usual Care Program
- Where
- India
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Prenatal Depression, Ketamine
Low-dose S-Ketamine and Postpartum Depression in Parturients With Prenatal Depression
Prenatal depression is an important risk factor of postpartum depression. Low-dose ketamine has been used for depression treatment. As a stereoisomer of ketamine, s-ketamine has similar effects to ketamine in anti-depression.
- Conditions
- Prenatal Depression, Ketamine, Postpartum Depression
- Trial name
- NCT03927378
- Testing
- S-ketamine
- Where
- 7 sites in China
- Volunteers
- 364 people
- Sponsor
- Peking University First Hospital
Depression, Clinical Depression
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records
- Conditions
- Depression, Clinical Depression, Depression, Anxiety, Depression, Postpartum
- Trial name
- NCT04211467
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Postpartum Depression
Stories That Empower Mothers and Postpartum Depression
Postpartum depression is a condition that occurs after birth and is difficult for mothers. Research shows that experiencing postpartum depression once increases the risk of experiencing it in subsequent pregnancies.
- Trial name
- NCT06787300
- Testing
- Stories that Empowered Mother
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ege University
Depression, Pregnancy Related
Exercise in Pregnancy and Risk of Postpartum Depression
The prevalence of postpartum depression (PPD) varies between 11.9% and 19.2% during the perinatal period. PPD refers to minor and major depression incidents that occur during pregnancy or shortly after (up until 12 months after…
- Trial name
- NCT06355375
- Testing
- exercise in pregnancy
- Where
- Italy
- Volunteers
- 398 people
- Sponsor
- Federico II University
Feeding Disorders, Mother-Child Relations
Mother-Child Interactions During Feeding
The feeding process is based on a mutual relationship and interaction, as it takes place with the active participation of the child and the parent.
- Conditions
- Feeding Disorders, Mother-Child Relations, Feeding; Disorder, Nonorganic Origin, in (Very Young) Child, Postpartum Depression
- Trial name
- NCT05664529
- Testing
- Chatoor Feeding Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Marmara University
Depression, Postpartum, Pregnancy
Labor Pain and Postpartum Behavioral Health Outcomes Study
In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric…
- Conditions
- Depression, Postpartum, Pregnancy, Child Development, Pain
- Trial name
- LPPD (NCT02692404)
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Other Chronic Postoperative Pain
High Pain Intervention in Cesarean Sections
In previous studies the investigators have seen that the severity of pain one day after cesarean delivery can predict the presence of pain and depression 2 months later.
- Trial name
- NCT01298778
- Testing
- Duramorph 150, Acetaminophen, Duramorph 300
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Wake Forest University Health Sciences
Depression, Depression, Postpartum
Effectiveness of Supplemental Calcium in Preventing Postpartum Depression
This study will evaluate the effectiveness of taking supplemental calcium while pregnant in reducing the risk of postpartum depression.
- Trial name
- NCT00228033
- Testing
- Elemental calcium (as carbonate)
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Post Partum Depression
Exercise and Socialization in Post-partum Depression
This community-engaged research project aims to address the critical need for alternative treatments of post-partum depression (PPD).
- Trial name
- NCT06801847
- Testing
- Socialization, Walking, Moderate Exercise
- Sponsor
- Laura Peterson-Brown
Postpartum Depressive Symptoms, Breastfeeding
Mediterranean Diet on Postpartum Depression
Optimal maternal nutrition and mental well-being are important for successful breastfeeding and maternal and infant health. The objective of this randomized controlled study was to evaluate the effect of a Mediterranean diet…
- Trial name
- NCT07793864
- Testing
- Mediterranean diet, Standard nutrition information
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Postpartum Depression
Personality Style and Self Compassion in Postpartum Depression: An Online Prevention Study
The primary aim of this study is to assess the relationship between personality style, self-compassion and depression during pregnancy, to identify psychological risk factors, particularly personality styles, that may contribute…
- Trial name
- NCT02813174
- Testing
- Compassionate Mind Training from Compassion-Focused Therapy
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- i4Health
Mothers, Fathers
The Effect of Baby Care Training Given to Fathers After Birth
The aim of this study is to provide infant care training to fathers and to measure father-infant attachment and maternal postpartum depression and quality of life.
- Trial name
- Babycare (NCT05588089)
- Testing
- Training group
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hitit University
Perinatal Problems, Post Traumatic Stress Disorder
Initial Intervention Efficacy for an Online PTSD Intervention for Pregnant Women
The current study aims to test a brief computer-assisted intervention (psychoeducation + skills) for pregnant women with elevated PTSD symptoms.
- Conditions
- Perinatal Problems, Post Traumatic Stress Disorder, Post Partum Depression
- Trial name
- NCT04264520
- Testing
- PTSD Psychoeducation + Skills Intervention
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medical University of South Carolina
Postpartum Depression
Emotional Freedom Techniques (EFT) and Postpartum Depression
Hypothesis 1: Pregnant women in the EFT group will have a lower test score from Edinburgh Postpartum Depression Scale, and a follow-up score of three months and six months after the last application date, compared to the control…
- Trial name
- NCT04355091
- Testing
- Emotional Freedom Techniques (EFT)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Istanbul University - Cerrahpasa