Clinical trials: Puerperal Disorder
Sexually Transmitted Infection, Alcohol Use Complicating the Puerperium
Technology-Based Intervention for Reducing Sexually Transmitted Infections and Substance Use During Pregnancy
This proposed study is to test whether Health Check-up for Expectant Moms (HCEM), a computer-delivered screening and brief intervention (SBI) that simultaneously targets sexually transmitted infection (STI) risk and alcohol/drug…
- Conditions
- Sexually Transmitted Infection, Alcohol Use Complicating the Puerperium, Alcohol Use Complicating Pregnancy, Unspecified Trimester, Drug Use
- Trial name
- NCT03826342
- Testing
- Health Check-up for Expectant Moms, Time, attention, and information-matched control
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Michigan
Hypertension
Monitoring and Testing of Blood Pressure in Postpartum Women
The purpose of this research study is to find out the usefulness of checking a woman's blood pressure remotely (at home) for 3 weeks after being discharged from the hospital after having a baby (or babies).
- Trial name
- SMART-BP (NCT05236725)
- Testing
- Remote Blood Pressure Cuff, Blood pressure monitoring smart phone app, BabyScripts™, Instructions
- Where
- United States
- Volunteers
- 1,607 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Sleep Disordered Breathing, Nocturnal Oxygen Desaturation
Determination of the Predictors of Nocturnal Desaturation in Postpartum Women
The primary aim of the study is to evaluate the effect of the method of delivery (vaginal delivery vs. cesarean section) on oxygen saturation in the first postpartum night.
- Conditions
- Sleep Disordered Breathing, Nocturnal Oxygen Desaturation, Upper Airway Edema
- Trial name
- NCT02330055
- Testing
- Forty-five degrees elevated upper body position, non-elevated upper body position, Noninvasive wrist pulse oximeter (WristOx Model 3150)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Massachusetts General Hospital
Diphtheria, Pertussis
Tdap Vaccine in Post-Partum Women
Monitoring immune response and longevity in serum and milk after Tdap administration to postpartum women. The clinical trial will involve women (aged 18 - 45 years) who have just delivered full-term infants (greater than or equal…
- Conditions
- Diphtheria, Pertussis, Tetanus
- Trial name
- NCT01711645
- Testing
- Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbed onto aluminum phosphate
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Viremia
Enhanced Virologic Monitoring for Pregnant and Postpartum Women With HIV
The goal of this study is to learn about supporting pregnant and postpartum women living with HIV with treatment adherence. The investigators will conduct a pilot study of an intervention that includes peer counseling about viral…
- Conditions
- HIV Infections, Viremia, Pregnancy Related
- Trial name
- NCT05845619
- Testing
- Enhanced virologic monitoring
- Where
- 4 sites in Kenya
- Volunteers
- 550 people
- Sponsor
- University of California, San Francisco
Perinatal Depression, Postpartum Depression
Development, Feasibility and Acceptability of Fathers and Babies (FAB): A Pilot Study
During this project the investigators will develop and pilot test a companion intervention for fathers (Fathers and Babies-FAB), to supplement the Mothers and Babies Course (MB) that provides stress and mood management tools for…
- Conditions
- Perinatal Depression, Postpartum Depression, Depression
- Trial name
- NCT03427528
- Testing
- Fathers and Babies (FAB), MB 1-on-1 plus TXT
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postpartum Hemorrhage
Feasibility Trial of the Circumferential Abdominal Pelvic Pressure Device (CAPP)
A group of midwives and obstetric nurses have been trained to use circumferential abdominal pelvic pressure (CAPP) to treat postpartum hemorrhage.
- Trial name
- NCT01497756
- Testing
- CAPP use
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of New Mexico
Hypertensive Disorder of Pregnancy
Remote BP Monitoring in the PP Period
The purpose of this study is to trial remote patient monitoring (RPM) in the postpartum hypertensive population in a randomized control design, with an aim to increase the number of blood pressure measurements taken during the…
- Trial name
- NCT03728790
- Testing
- Remote Patient Monitoring
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Columbia University
Pain Management, Vaginal Delivery
Post-partum Non-pharmacologic Pain Management
This study aims to examine whether use of an abdominal binder for postpartum patients after vaginal delivery can effectively manage their pain and reduce the need for pharmacologic analgesics.
- Trial name
- NCT03903172
- Testing
- Abdominal binder
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Wright State University
Postpartum Anemia
Safety and Efficacy of a Hematinic Agent in the Treatment of Postpartum Patients
The purpose of this study is to evaluate the efficacy, safety, and tolerability of VIT45 compared to the current standard of care in postpartum patients.
- Trial name
- NCT00354484
- Testing
- Ferric Carboxymaltose (FCM), Ferrous Sulfate tablets
- Where
- United States
- Volunteers
- 291 people
- Sponsor
- American Regent, Inc.
Depression, Postpartum
The Effects of Light Therapy on Circadian Rhythms, Sleep, and Mood in Postpartum Depression
The proposed study aims to establish the feasibility of light therapy for postpartum depression delivered via Re-Timer, demonstrate its preliminary efficacy, and illuminate relationships between circadian shifts and mood changes…
- Trial name
- NCT02769858
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Michigan
Hypertension in Pregnancy, Preeclampsia Severe
Comparing Nifedipine and Enalapril in Medical Resources Used in the Postpartum Period
This study evaluates whether nifedipine or enalapril is better at decreasing the amount of medical resources used in the postpartum period by women who have high blood pressure in pregnancy and the postpartum period.
- Conditions
- Hypertension in Pregnancy, Preeclampsia Severe, Gestational Hypertension, Postpartum Preeclampsia
- Trial name
- NCT04236258
- Testing
- NIFEdipine ER, Enalapril
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
COVID-19, Pregnancy Complications
Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic
The purpose of this study is to assess the health and wellbeing of pregnant and recently pregnant women during the COVID-19 pandemic using an online survey.
- Conditions
- COVID-19, Pregnancy Complications, Mental Health Wellness 1, Anxiety
- Trial name
- NCT04385238
- Testing
- This is an online survey with no intervention.
- Where
- United States
- Volunteers
- 6,894 people
- Sponsor
- Pregistry
HIV Infections
Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy
IMPAACT P1026s is a Phase IV prospective clinical study to evaluate the pharmacokinetics (PKs) of antiretroviral (ARV) and tuberculosis (TB) medications in pregnant women and their infants.
- Trial name
- NCT00042289
- Testing
- atazanavir/cobicistat, darunavir/ritonavir dosage #1, darunavir/ritonavir dosage #2
- Where
- 62 sites in United States, Argentina and 6 more
- Volunteers
- 1,578 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cardiovascular Disease, Preeclampsia
Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia
This study will compare two arms in a randomized clinical trial of cardiovascular risk prevention in women with a history of preeclampsia.
- Conditions
- Cardiovascular Disease, Preeclampsia, Hypertension, Post-partum Weight Retention
- Trial name
- HH4M (NCT02147626)
- Testing
- Web-based educational and motivational modules, Information and Screening Group
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Postpartum Sepsis, Postpartum Endometritis
Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries
This study, performed over a course of 3 years in 5 collaborating hospitals in Cameroon, Africa, will randomize 750 women in labor with prolonged rupture of membranes ≥ 8 hours or prolonged labor ≥ 18 hours to identical oral…
- Conditions
- Postpartum Sepsis, Postpartum Endometritis, Postpartum Fever
- Trial name
- NCT03248297
- Testing
- Azithromycin, Azithromycin and amoxicillin
- Where
- Cameroon
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hypertension in Pregnancy, Preeclampsia
Response to Anti-hypertensives in Pregnant and Postpartum Patients
In this study, the investigators will evaluate the blood pressure response to nifedipine and labetalol in pregnant and postpartum patients, who present with hypertensive disease in pregnancy with severe range blood pressure…
- Trial name
- NCT03506724
- Testing
- Nifedipine, Labetalol
- Where
- 2 sites in United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Depression, Postpartum
Effectiveness of Sertraline Alone and Interpersonal Psychotherapy Alone in Treating Women With Postpartum Depression
This study will evaluate the effectiveness of antidepressant medication alone and interpersonal psychotherapy alone in treating women with postpartum depression.
- Trial name
- NCT00602355
- Testing
- Sertraline, Interpersonal psychotherapy (IPT), Clinical management
- Where
- 2 sites in United States
- Volunteers
- 162 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Preeclampsia, Preeclampsia Severe
Nudge to Drive Transitions of Care
Hypertensive disorders of pregnancy (HDP) are stress tests which may identify women at high risk of future cardiovascular disease (CVD), the leading cause of death among women.
- Conditions
- Preeclampsia, Preeclampsia Severe, Gestational Hypertension, Hypertensive Disorder of Pregnancy
- Trial name
- REMIND (NCT04660032)
- Testing
- Nudge
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- University of Pennsylvania
Hypertension in Pregnancy, Postpartum Preeclampsia
Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension
The purpose of this study is to see if a combined pill of Angiotensin-converting enzyme (ACE) inhibitors (a medication that helps relax your veins and arteries to lower your blood pressure) with diuretics (sometimes called water…
- Trial name
- ACE (NCT05049616)
- Testing
- ACE Inhibitors and Diuretics, NIFEdipine ER
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The University of Texas Health Science Center, Houston