Clinical trials: Pulmonary Coin Lesion
Pulmonary Nodule, Solitary
Methylation of cfDNA in Diagnosing and Monitoring Pulmonary Nodule
Patients found pulmonary nodules by CT screening by will be enrolled in this study prospectively. Plasma cfDNA sequencing of these patients will be used to diagnose and monitor benign and malignant pulmonary nodules.
- Trial name
- NCT03989219
- Testing
- plasma cfDNA methylation
- Where
- China
- Volunteers
- 401 people
- Sponsor
- Jiayuan Sun
Lung Neoplasms
Pre-operative Localization of Ground Glass Solitary Pulmonary Nodules
Objectives: The main drawback of the hook-wire technique for locating ground glass nodules before video assisted thoracoscopic surgery (VATS) resection is the risk of the hook dislodging during single lung ventilation as the lung…
- Trial name
- SLIDINGWIRE (NCT06195657)
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pulmonary Coin Lesion, Colon Cancer Liver Metastasis
Optical Detection of Malignancy During Percutaneous Interventions
Investigation of application possibilities of optical spectroscopy within the field of oncology. Optical spectroscopy enables the possibility to specifically differentiate between different (human) tissues.
- Conditions
- Pulmonary Coin Lesion, Colon Cancer Liver Metastasis, Breast Cancer
- Trial name
- NCT01730365
- Testing
- Core biopsy procedure
- Where
- Netherlands
- Volunteers
- 104 people
- Sponsor
- Philips Healthcare
Solitary Pulmonary Nodules
Near Infrared Fluorescence Imaging With Indocyanine Green
This research study will evaluate how Near Infrared Fluorescence imaging (NIFI) with indocyanine green (ICG) contrast dye can assist in the identification and diagnosis of lung nodules during surgery.
- Trial name
- NIFI-ICG (NCT02851368)
- Testing
- near infrared fluorescence imaging (NIFI), Indocyanine Green
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh
Solitary Pulmonary Nodule, Bronchial Neoplasms
ThoHSpEkt Thoracoscopic Ectomy of Radioactively Marked Pulmonary Nodules With Free-hand SPECT
Title ThoHSpEkt Study Design Pilot Study concerning the technical operative methods and a phase II study concerning the radiopharmaceutical (therapeutic-explorative study with an approved drug in a new indication) Location…
- Trial name
- ThoHSpEkt (NCT02050724)
- Testing
- Radioactive labelling of pulmonary nodules, CT guided radioactive labelling, Electromagnetic guided bronchoscopic radioactive labelling
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- Cantonal Hospital of St. Gallen
Solitary Lung Nodule, Multiple Pulmonary Nodules
A Prospective, Non-interventional Cohort Study of Subsolid Pulmonary Nodules
Some studies have shown that the model for judging and predicting the growth of sub-solid pulmonary nodules through big data and deep learning can detect nodule growth earlier.
- Trial name
- NCT06458673
- Where
- China
- Volunteers
- 1,184 people
- Sponsor
- Guangdong Provincial People's Hospital
Solitary Pulmonary Nodule
Evaluate the Auxiliary Diagnostic Value of Circulating Tumor Cells in Benign and Malignant Lung Nodules
By testing the CTC number of new solitary pulmonary nodule patient, evaluating the correlation of CTC number and benign and malignant lung nodules auxiliary diagnosis, the correlation of CTC number and the size of lung nodules of…
- Trial name
- NCT02653859
- Volunteers
- 50 people
- Sponsor
- GenoSaber
Pulmonary Nodules, Multiple, Pulmonary Nodules, Solitary
Differentiation of Benign and Malignant Pulmonary Nodules by Volatile Organic Compounds in Human Exhaled Breath
The goal of this observational study is to develop an advanced expiratory algorithm model utilizing exhaled breath volatile organic compound (VOC) markers.
- Conditions
- Pulmonary Nodules, Multiple, Pulmonary Nodules, Solitary, Lung Cancer
- Trial name
- NCT06518655
- Testing
- Gas chromatography-mass spectrometry(GC-MS) and micro Gas Chromatography-photoionisation detector (μGC-PID) system
- Where
- 15 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- ChromX Health
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
iNod™ Ultrasound-Guided Needle Biopsy System Study
The purpose of this study is to collect information on the iNod™ System's safety and ability to see the iNod™ biopsy needle in real-time in endobronchial lesions, peripheral lung nodules, or lung masses.
- Conditions
- Solitary Pulmonary Nodule, Multiple Pulmonary Nodules, Biopsy, Fine-Needle
- Trial name
- NCT05804435
- Testing
- iNod™ System
- Sponsor
- Boston Scientific Corporation
Pulmonary Nodule, Solitary, Peripheral Pulmonary Nodules
Intraoperative Longitude-Latitude-Depth Localization Versus Preoperative CT-Guided Percutaneous Lung Puncture Localization for 0.8-2 cm Peripheral Pulmonary Nodules
The goal of this clinical trial is to learn whether intraoperative longitude-latitude-depth three-dimensional localization (LLD localization) is non-inferior to preoperative CT-guided percutaneous lung puncture localization for…
- Conditions
- Pulmonary Nodule, Solitary, Peripheral Pulmonary Nodules, Pulmonary Nodules
- Trial name
- NCT07675889
- Testing
- Longitude-Latitude-Depth Localization, CT-Guided Percutaneous Lung Puncture Localization
- Where
- 4 sites in China
- Volunteers
- 274 people
- Sponsor
- Qilu Hospital of Shandong University
Lung Cancer, Pulmonary Nodule, Solitary
Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulES
This is a pragmatic clinical trial that will study the effect of a radiomics-based computer-aided diagnosis (CAD) tool on clinicians' management of pulmonary nodules (PNs) compared to usual care.
- Trial name
- ARCADES (NCT05968898)
- Testing
- Optellum Virtual Nodule Clinic
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Solitary Pulmonary Nodules
Clinical Evaluation of CARESTREAM Dual Energy and Digital Tomosynthesis
The purpose of this study is to evaluate the imaging performance of Dual Energy and Digital Tomosynthesis (DE-DT) application against the commercially available predicate devices.
- Trial name
- NCT02531646
- Testing
- Radiation
- Volunteers
- 66 people
- Sponsor
- Carestream Health, Inc.
Lung Nodule, Solitary, Lung Nodule
Iriscope for the Diagnosis of Peripheral Pulmonary Lesions: a Multicentre Randomised Controlled Trial
A pulmonary nodule is a small mass detected in your lungs during a scan. When a nodule is suspicious, we need to determine its nature (benign or malignant). To do this, a bronchoscopy is performed.
- Conditions
- Lung Nodule, Solitary, Lung Nodule, Lung Cancer (Diagnosis)
- Trial name
- NCT07798362
- Testing
- Use of Iriscope via guide sheath to guide biopsies, Bronchoscopy
- Volunteers
- 140 people
- Sponsor
- Erasme University Hospital
Benign and Malignant Solitary Pulmonary Nodules
(PET) Imaging in the Management of Patients With Solitary Pulmonary Nodules
All patients with a new, untreated solitary pulmonary nodule (SPN) between 7 mm and 3 cm in diameter identified by chest x-ray, will be approached to undergo positron emission tomography (PET) and computerized tomography (CT).
- Trial name
- NCT00032331
- Testing
- PET Imaging, CT scan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Yield of Cryo Biopsy in Lung Cancer, Solitary Pulmonary Nodule
EBUS Guided Cryo Biopsy of Solitary Pulmonary Nodules
To proof the feasibility and safety of EBUS guided transbronchial cryo biopsies in peripheral lung lesions
- Trial name
- NCT01221493
- Testing
- Cryo biopsy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Heidelberg University
Pulmonary Nodule, Solitary, Smoking Behaviors
Smoking Cessation Before Bronchoscopy or CT-guided Puncture
Nicotine is the most common preventable cause of death and is responsible for over seven million deaths worldwide. If current trends continue, tobacco will kill more than eight million people worldwide every year by 2030.
- Trial name
- NCT07322796
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- RWTH Aachen University
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Evaluate the Utility of the ProLung China Test in the Diagnosis of Lung Cancer
A Study to evaluate the utility of the ProLung China Test as an adjunct to CT scan in the diagnosis of lung cancer.
- Trial name
- ProLung (NCT02726633)
- Where
- 3 sites in China
- Volunteers
- 500 people
- Sponsor
- Chinese Alliance Against Lung Cancer
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Intravenous Indocyanine Green for Localization of Intra-thoracic Lesions
This is a clinical trial to evaluate the intravenous administration of indocyanine green (ICG) as a method of intra-thoracic lesion localization.
- Trial name
- NCT03097627
- Testing
- ICG Intervention, Near Infrared Camera
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Brigham and Women's Hospital
Pulmonary Nodules, Solitary
Virtual Bronchoscopic Navigation to Increase Diagnostic Yield in Patients With Pulmonary Nodules
Background Transthoracic computed tomography (CT)-guided procedures are the current gold Standard for obtaining diagnostic biopsies of solitary pulmonary nodules (SPN) in the peripheral lung.
- Trial name
- NAVIGATOR (NCT05383105)
- Testing
- Virtual bronchoscopic navigation
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- University Medical Center Groningen
Pulmonary Nodule, Solitary, Lung Cancer
Pulmonary Nodule Cohort
The aim of this study is to identify the clinical features of pulmonary nodules and establish a cohort to identify biomarkers for lung cancer.
- Trial name
- liquidNodule (NCT04049422)
- Volunteers
- 1,000 people
- Sponsor
- Seoul National University Hospital