Clinical trials: Pulmonary Disease, Chronic Obstructive
Chronic Obstructive Pulmonary Disease
Biomarkers in Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality worldwide and is characterized by fixed airflow obstruction.
- Trial name
- NCT01145300
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Leiden University Medical Center
COPD
Physiotherapy in Patients With Stable Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is a lung disease that is characterized by incompletely reversible airflow obstruction. It is projected to be the fifth leading burden of disease worldwide by the year 2020.
- Trial name
- NCT02517411
- Testing
- Standard care, Physiotherapy added to standard care
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
Pulmonary Disease, Chronic Obstructive
A Clinical Trial of TQC3721 Suspension for Inhalation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
To evaluate the efficacy and safety of TQC3721 Suspension for Inhalation in patients with moderate to severe Chronic obstructive pulmonary disease (COPD)
- Trial name
- NCT06527144
- Testing
- 3mg TQC3721 Suspension for Inhalation, 6mg TQC3721 Suspension for Inhalation
- Where
- 28 sites in China
- Volunteers
- 240 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
COPD
Acoustic and Volumetric Measurements in Order to Objectify Bronchial Congestion in Patients With Obstructive Respiratory Pathologies Within the Framework of Their Management in Respiratory Physiotherapy for Decongestion
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease defined by permanent airway obstruction. In this disease, a large part of the muscular work is taken up by breathing (fight against bronchial, parietal…
- Trial name
- MUKROBS (NCT05480163)
- Testing
- Measurement records
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Association des Réseaux Bronchiolite
Asthma, Chronic Obstructive Pulmonary Disease
PK of BDP/FF/GB Single-inhaler Triple Therapy in Japanese vs. Caucasians
The purpose of conducting this study is to obtain PK data of Beclometasone Dipropionate (BDP)/Beclometasone-17-MonoPropionate (B17MP), Formoterol Fumarate (FF) and Glycopyrronium Bromide (GB) after inhalation of CHF 5993 in…
- Trial name
- NCT03859414
- Testing
- Therapeutic Dose 1, Therapeutic Dose 2, Supra-therapeutic Dose
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
COPD
Study of Chronic Obstructive Pulmonary Disease (COPD) Exacerbations In Spain
ECOS is a cross-sectional, observational, longitudinal, multicenter study enrolling 100-200 patients during a COPD exacerbation.
- Trial name
- ECOS (NCT01750658)
- Where
- Spain
- Volunteers
- 99 people
- Sponsor
- Cimera
COPD (Chronic Obstructive Pulmonary Disease), Pulmonary Rehabilitation
EFFECTIVENESS OF COMBINED CONCENTRIC AND ECCENTRIC AEROBIC EXERCISE ON A TREADMILL IN PATIENTS WITH COPD: A RANDOMIZED CLINICAL TRIAL.
The aim of this study is to demonstrate the effectiveness of combined concentric and eccentric aerobic training in subjects with COPD, in terms of strength, lung capacity, functionality, and short-term health quality.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Pulmonary Rehabilitation, Eccentric Exercise Training
- Trial name
- NCT07627035
- Testing
- Eccentric and concentric aerobic exercice versus only concentric aerobic exercice
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Europea de Madrid
Implementation of a Chronic Disease Management Programme, COPD
Effects of an Active Implementation of a Guideline for Chronic Obstructive Pulmonary Disease
Aims: To design a proactive implementation strategy for a chronic-disease-management-programme. To describe effects of the active implementation of a programme for COPD-patients measured on patient-related goals and use of health…
- Trial name
- NCT01228708
- Testing
- Active implementation of a guideline for chronic disease
- Volunteers
- 3,021 people
- Sponsor
- University of Aarhus
Copd, Aging
Evaluation of Cardiac Variability After a Vitamine D Protocol and Whole Body Vibration
Evaluation of heart rate variability in time and frequency domains, in Chronic Obstructive Pulmonary Disease (COPD) after 03 months of vitamine D supplementation and whole body vibration (WBV) training
- Trial name
- NCT03679325
- Testing
- vitamine D, whole body vibration (WBV)
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Maíra F Pessoa
Cough
An Investigation Into the Mechanism of Inhalation Cough Challenge
Despite its commonplace use in respiratory medicine the mechanism whereby inhalation challenge with a variety of mild acid aerosols produces a dose related and predictable cough is unknown.
- Trial name
- NCT02039999
- Testing
- Nebulised citric acid in serial dilutions, Nebulised ATP solution in serial dilutions, Nebulised TRPA1 agonist solution in serial dilutions
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
COPD, Lung Cancers
Assessment the Effectiveness of BTVA in COPD and Ablation in Pulmonary Nodules by Pulmonary MRI
A Clinical Study Based on Magnetic Resonance Imaging of the Lungs to Assess the Efficacy of Thermal Vapor Ablation and Pulmonary Nodule Ablation in Chronic Obstructive Pulmonary Disease After Surgery.
- Trial name
- NCT07045532
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Chest Hospital
COPD
Effect of QVA149 on Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This study assessed the effect of once-daily indacaterol and glycopyrronium bromide (QVA149) on exercise endurance in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- BRIGHT (NCT01294787)
- Testing
- indacaterol and glycopyrronium bromide (QVA149), tiotropium
- Where
- 13 sites in Germany, Spain
- Volunteers
- 85 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease, Lung Non-Small Cell Carcinoma
A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence
This early phase I trial studies the side effects of a vaccine called CIMAvax-EGF and to see how well it works in preventing lung cancer from developing in patients at high risk for lung cancer or coming back (recurrence) in…
- Conditions
- Chronic Obstructive Pulmonary Disease, Lung Non-Small Cell Carcinoma, Pneumonia, Stage IB Lung Cancer AJCC v8
- Trial name
- NCT04298606
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Roswell Park Cancer Institute
Chronic Obstructive Pulmonary Disease
Efficacy and Safety of Tulobuterol Patch Combined With Tiotropium Bromide for Relieving Dyspnea Symptom of Chronic Obstructive Pulmonary Disease
Phrase: IV Indication: dyspnea symptom of chronic obstructive pulmonary disease (COPD) Objective: to evaluate efficacy and safety of tulobuterol patch combined with Tiotropium bromide for relieving dyspnea symptom of COPD Design…
- Trial name
- NCT01465906
- Testing
- tulobuterol, Tiotropium Bromide
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Zhongshan Hospital
Pulmonary Disease, Chronic Obstructive
A Study Using US Medical and Pharmacy Claim Records to Compare the Resource Use, Cost, and Outcomes of People With COPD Who Take Either Tiotropium + Olodaterol or Fluticasone + Umeclidinium + Vilanterol
The purpose of this study is to estimate disease-related and all-cause burden and clinical outcomes of interest following initiation of chronic obstructive lung disease (COPD) maintenance therapy with Tiotropium…
- Trial name
- NCT05127304
- Testing
- Trelegy Ellipta, Stiolto Respimat, Furoate/Umeclidinium/Vilanterol
- Where
- United States
- Volunteers
- 11,316 people
- Sponsor
- Boehringer Ingelheim
Acute Exacerbation of Chronic Obstructive Airways Disease
β2-agonist Versus Ipratropium Bromide Associated With β2-agonists in Chronic Obstructive Pulmonary Disease Exacerbation
The effectiveness of β2-agonists in the treatment of exacerbations of COPD is already established. The purpose of this study is to compare the effectiveness of the β2-agonists alone in nebulization with the association…
- Trial name
- NCT01944033
- Testing
- Bricanyl/Iprovent, Bricanyl
- Where
- 2 sites in Tunisia
- Volunteers
- 250 people
- Sponsor
- University of Monastir
COPD
Effects of Endoscopic Lung Volume Reduction on Diaphragm Function and Conformation
Chronic obstructive lung disease (COPD) is a common disease that is frequently complicated by hyperinflation. The resulting increase in lung volume impairs the diaphragmatic function because of a shortening of the diaphragmatic…
- Trial name
- NCT05799352
- Testing
- Endoscopic lung volume reduction
- Where
- Belgium
- Volunteers
- 35 people
- Sponsor
- Erasme University Hospital
Lung Cancer, COPD
DEPRECAP: Lung Cancer Screening Programme by LDCT for Patients With COPD or Emphysema.
The DEPRECAP (Early detection of lung cancer) study is an ongoing, prospective, longitudinal, multicenter lung cancer screening program that recruited individuals with COPD or emphysema from the pulmonary clinics of Fundación…
- Conditions
- Lung Cancer, COPD, Emphysema
- Trial name
- DEPRECAP (NCT06690385)
- Where
- 2 sites in Spain
- Volunteers
- 1,998 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
COPD (Chronic Obstructive Pulmonary Disease)
The Effect of Acupressure on Dyspnea and Anxiety Levels
The aim of this study is to determine the effect of acupressure applied to individuals with COPD on dyspnea and anxiety. It is important for the transfer of nonpharmacological methods to clinical applications.
- Trial name
- nursing (NCT06752915)
- Testing
- acupressure application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- ÇİĞDEM ERGİN
Pulmonary Disease, Chronic Obstructive, Adverse Effect of Glucocorticoids and Synthetic Analogues
Reduction of Corticosteroid Use in Outpatient Treatment of Exacerbated COPD
Background Chronic obstructive pulmonary disease (COPD) is a major public health issue with no curative treatment. In Switzerland estimated 5-7% of the total population are suffering from this chronic disease.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Adverse Effect of Glucocorticoids and Synthetic Analogues, Disease Exacerbation
- Trial name
- RECUT (NCT02386735)
- Testing
- Prednisone
- Where
- Switzerland
- Volunteers
- 133 people
- Sponsor
- Prof. Dr. Jörg Leuppi