Clinical trials: Pulmonary Disease, Chronic Obstructive
Chronic Pain
The Effect of Perioperative Pregabalin on the Incidence of Chronic Post-thoracotomy Pain Syndrome
Pregabalin, administered prior to and following lateral thoracotomy surgery will reduce the likelihood of chronic post-thoracotomy pain syndrome (CPTPS).
- Trial name
- NCT00998816
- Testing
- Pregabalin
- Where
- Canada
- Sponsor
- Queen's University
Chronic or Recurrent Appendicitis
Laparoscopic Appendectomy for Chronic Right Lower Abdominal Pain
It is questionable whether elective appendectomy can effectively reduce pain in persistent or recurrent lower abdominal quadrant pain due to chronic appendicitis.
- Trial name
- NCT00413855
- Testing
- laparoscopic appendectomy or not (surgery)
- Volunteers
- 40 people
- Sponsor
- Maxima Medical Center
Depression, COPD
Prevalence and Predictors of Depression in COPD
Depression adversely affects quality of life in COPD patients, associated with higher rate of exacerbations, admissions and mortality. However, local prevalence rate of depression in geriatric COPD patients remains unknown.
- Trial name
- NCT02415140
- Testing
- Rate of depression
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Kwong Wah Hospital
COPD, Spirometry
Evaluation of a Mobile Application to Facilitate the Interpretation of Spirometry by Family Physicians and Residents
Problematic: Spirometry is used to objectify the obstructive syndrome defining chronic obstructive pulmonary disease (COPD). However, this test remains underused in the primary care.
- Conditions
- COPD, Spirometry, Mobile Application
- Trial name
- NCT03206606
- Testing
- SPIRO
- Where
- 8 sites in Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease
Vibration Training in Chronic Obstructive Pulmonary Disease (COPD)-Patients During a Three-week Rehabilitation
The aim of this study is to investigate the change of physical activity in COPD-patients performing a whole body vibration training additional to a standard three-week rehabilitation program in comparison to patients performing…
- Trial name
- NCT01380652
- Testing
- whole body vibration training
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Chronic Obstructive Pulmonary Disease
Cross-sectional Study to Investigate the Effects of Chronic Obstructive Pulmonary Disease on Daily Life Activities
The purpose of this study is to investigate the effects of Chronic Obstructive Pulmonary Disease (COPD) on daily life activities in patients with COPD and also to determine the socio-demographic profile, daily life style and…
- Trial name
- COPD LIFE (NCT01325948)
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 497 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Effectiveness of Acapella and ELTGOL Technique to Promote Airway Clearance in COPD:a Comparative Study
To compare the efficacy of acapella and expiration against open glottis (ELTGOL) technique in promoting airway clearance of chronic obstructive pulmonary disease (COPD) patients
- Trial name
- NCT02249455
- Testing
- Acapella, ELTGOL, conventional physiotherapy
- Where
- India
- Volunteers
- 30 people
- Sponsor
- PSG College of Physiotherapy
Hypoxia Altitude Simulation Test, High Altitude
Hypoxia-altitude Testing to Predict Altitude Related Adverse Health Effects in Chronic Obstructive Pulmonary Disease (COPD) Patients
The predictive value of the hypoxia altitude simulation test (HAST) or other baseline values to predict altitude-related adverse health effects (ARAHE) is not established.
- Trial name
- NCT04915378
- Testing
- hypoxia altitude simulation test (HAST) at 760m, High Altitude (3100m)
- Where
- Kyrgyzstan
- Volunteers
- 75 people
- Sponsor
- University of Zurich
Sinusitis, Chronic, Sinus Infection Chronic
Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adults
Purulent Oedematous Sinusitis (POS) is a particular form of chronic rhinosinusitis observed in 2% of the general population. In spite of its heavy impact on the quality of life, There is no established recommendation for the…
- Trial name
- SOPAZITHRO (NCT05157685)
- Testing
- Azithromycin Oral Tablet
- Where
- 13 sites in France
- Volunteers
- 230 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Asthma
Neural Mechanisms in Asthma
Asthma is a chronic disease that affects nearly 13% of adults in the U.S., causing substantial impairment that is reflected in the tens of millions of missed days of work, and doctors' and emergency room visits it leads to…
- Trial name
- NCT01155843
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Nasal Polyposis, Eosinophilic Chronic Rhinosinusitis
Efficacy and Safety Study of Benralizumab in Patient With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps (ORCHID)
This is a randomized, double-blind, placebo-controlled, parallel-group, international, multicenter, Phase 3 study to evaluate the efficacy and safety of repeat dosing of benralizumab 30 mg administered subcutaneously (SC) versus…
- Trial name
- ORCHID (NCT04157335)
- Testing
- Benralizumab 30 mg
- Where
- 116 sites in United States, Argentina and 15 more
- Volunteers
- 295 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Warm Homes for Elder New Zealanders
Aim The purpose of this study is to evaluate whether fuel subsidies reduce exacerbations of COPD among people aged over 55, and therefore whether providing such subsidies is a cost-beneficial policy initiative.
- Trial name
- WHEZ (NCT01627418)
- Testing
- Energy Voucher, No intervention : control arm
- Where
- 3 sites in New Zealand
- Volunteers
- 522 people
- Sponsor
- University of Otago
Chronic Obstructive Pulmonary Disease
the Effectivness of the Thoracic Cage Mobilization on COPD Patients
the study aims to investigate effectiveness of thoracic cage mobilizations on the chronic obstructive pulmonary diseases.
- Trial name
- NCT05448235
- Testing
- conventional treatment, thoracic mobilization
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Coronary Angiography and Intervention
The Primary Endpoint is to Compare the Incidence of Forearm RAO Between Distal and Traditional Radial Access Assessed by Vascular Ultrasound At Discharge
The primary endpoint is to compare the incidence of forearm RAO between distal and traditional radial access for coronary angiography and intervention
- Trial name
- RAO (NCT06688747)
- Volunteers
- 230 people
- Sponsor
- Assiut University
Respiratory Diseases, Lung Diseases
In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilation
Using an adult lung bench model of non invasive ventilation, the aim of the study is to compare an experimental system of breath-synchronized vibrating mesh nebulizer to a conventional vibrating mesh nebulizer during non invasive…
- Conditions
- Respiratory Diseases, Lung Diseases, Cystic Fibrosis, COPD
- Trial name
- Synchro-Neb (NCT02084043)
- Testing
- Nebulization of Amikacin during NIV (RR: 15 cycles/minute), Nebulization of Amikacin during NIV (RR: 25 cycles/minute)
- Where
- Belgium
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University Hospital St Luc, Brussels
Chronic Heart Failure
Snapshot Evaluation of Acute and Chronic Heart Failure in Real Life in Turkey
This study, which will be conducted at 23 sites representing the determined NUTS-1 regions in Turkey, in which all patients who were admitted to clinic or were hospitalized with Heart Failure (Acute or Chronic) diagnosis will be…
- Trial name
- SELFIE-TR (NCT02578225)
- Testing
- Non interventional study
- Where
- 23 sites in Turkey (Türkiye)
- Volunteers
- 1,054 people
- Sponsor
- Prof. Dr. Mehmet Birhan Yılmaz
COPD
Continuous Chest Wall Vibration in COPD Rehabilitation
Dyspnea, the sensation of breathing discomfort or shortness of breath, is one of the main symptoms for patients affected by Chronic Obstructive Pulmonary Disease (COPD), particularly during exercise.
- Trial name
- NCT03644888
- Testing
- Cycle ergometer training, Airway clearance program, Vibration therapy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Chronic Obstructive Pulmonary Disease
Effects of Temazepam in Patients With Chronic Pulmonary Obstructive Disease
The purpose of this study is to evaluate the effects of temazepam during sleep and in daytime on dyspnea, gas exchange and sleep quality in patients with chronic obstructive pulmonary disease.
- Trial name
- NCT00245661
- Testing
- Temazepam
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Rijnstate Hospital
Pulmonary Disease, Chronic Obstructive
Does Pulmonary Rehabilitation Improve Breathing of COPD Patients
Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death world-wide. Dyspnea (i.e., sensations of breathlessness) is the hallmark symptom of patients with this disease.
- Trial name
- PR-COPD (NCT01815970)
- Testing
- Pulmonary Rehabilitation
- Where
- Canada
- Sponsor
- University of British Columbia
Pulmonary Disease, Chronic Obstructive
Usage of Spacers and the Relationship With Symptoms Severity in COPD Elderly Patients
The goal of this observational study is to investigate the usage of spacers and their relationship with symptom severity in chronic obstructive pulmonary disease elderly patients.
- Trial name
- NCT06467162
- Where
- Taiwan
- Volunteers
- 164 people
- Sponsor
- Ai-Ling Chang