Clinical trials: Pulmonary Disease, Chronic Obstructive, completed
Chronic Obstructive Pulmonary Disease
Quality of Life in Daxas-treated Patients Older Than 18 Years With Severe Chronic Obstructive Pulmonary Disease (COPD) (DACOTA)
Chronic obstructive pulmonary disease (COPD) is a progressive and largely irreversible lung disease characterized by chronic bronchitis and/or emphysema, resulting in breathlessness, cough and sputum.
- Trial name
- DACOTA (NCT01285167)
- Testing
- Daxas
- Where
- 605 sites in Germany
- Volunteers
- 3,645 people
- Sponsor
- AstraZeneca
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Fat Metabolism in OSA and COPD
Obstructive sleep apnea (OSA) is the most common type of sleep apnea and is caused by an obstruction of the upper airways. The obstruction results in periods of intermittent hypoxia and re-oxygenation, which lead to increased…
- Conditions
- Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease, Obesity
- Trial name
- NCT02157844
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Chronic Obstructive Pulmonary Disease
A Clinical Trial of TQC3721 Suspension for Inhalation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease.
This is a phase II clinical trial to evaluate the efficacy and safety of TQC3721 Suspension for Inhalation in patients with moderate to severe Chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT05987371
- Testing
- TQC3721 suspension for inhalation, Salbutamol sulfate inhalation aerosol
- Where
- 11 sites in China
- Volunteers
- 75 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
Diet and Chronic Obstructive Pulmonary Disease
To examine the relationship of specific dietary factors to risk of chronic obstructive pulmonary disease.
- Trial name
- NCT00006419
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Moderate to Severe COPD Receiving Home Exercise Training
Mobile-phone-based Home Exercise in Chronic Obstructive Pulmonary Disease
Background: Moderate-intensity exercise training improves skeletal muscle aerobic capacity and increased oxidative enzyme activity, as well as exercise tolerance in Chronic Obstructive Pulmonary Disease (COPD) patients.
- Trial name
- NCT01631019
- Testing
- Mobile-phone-based Home Exercise Training Program, Home Exercise Training Program
- Where
- Taiwan
- Volunteers
- 26 people
- Sponsor
- Chang Gung Memorial Hospital
Autonomic Function in Patients With Chronic Obstructive Pulmonary Disease
Autonomic Function in Patients With COPD
Conduct an in-depth evaluation of autonomic function using a validated tests, assess genetic aspects of autonomic failure, and determine the correlation between of autonomic function failure and other clinical variables in…
- Trial name
- NCT05667311
- Testing
- ECG
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- University Hospital, Ghent
Chronic Obstructive Pulmonary Disease
Hydrolyzed Casein and Whey Protein Supplementation and the Addition of Leucine to Induce Protein Anabolism in Malnourished COPD Patients
The aim of this study is the first aim of a NIH project that consists of 3 aims. The first aim examines the acute effects of two high-quality milk proteins (casein vs.
- Trial name
- NCT01154400
- Testing
- Casein protein hydrolysates, Whey protein hydrolysates, Casein protein hydrolysates + LEU
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Texas A&M University
COPD
Validation of Urdu Version of Leicester Cough Questionnaire (LCQ)
Leicester Cough Questionnaire (LCQ) is a patient reported, 19-item tool, and it comprised physical, psychological, and social elements.
- Trial name
- NCT06674395
- Where
- Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease (COPD)
A First Time in Man Study to Asses the Safety and Tolerability of AZD7624 in Healthy Subjects
This is a First in Human study to assess the safety and tolerability of AZD7624, following inhaled administration of single ascending doses in healthy male volunteers and female volunteers of non-child bearing potential.
- Trial name
- NCT01754844
- Testing
- AZD7624
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
COPD, Asthma
Participatory Action Research to Evaluate the Delivery of the MISSION ABC Service Model and Assess Health Service and Clinical Outcomes
Innovations aimed at improving new patient identification, diagnosis, nonpharmacological treatment, supported self-management, and remote monitoring, together with new methods of clinical support could improve outcomes in…
- Conditions
- COPD, Asthma, Breathlessness
- Trial name
- NCT03096509
- Testing
- MISSION ABC Integrated Care clinic
- Where
- United Kingdom
- Volunteers
- 342 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Asthma, COPD
Prehospital Emergency Care of Obstructive Respiratory Emergencies With the Use of Teleconsultation
The aim of the study is to investigate the quality of prehospital emergency care in acute respiratory emergencies, when paramedics are supported telemedically by an EMS physician.
- Trial name
- NCT01644045
- Testing
- Teleconsultation
- Where
- Germany
- Volunteers
- 17 people
- Sponsor
- RWTH Aachen University
Stable COPD Patients
Effect of Vitamin D3 on Lung Function and Exercise Tolerance in COPD Patients
Background: Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality throughout the world which is a preventable as well as treatable disease.
- Trial name
- NCT03781895
- Testing
- Cholecalciferol
- Where
- Bangladesh
- Volunteers
- 48 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Emphysema
Assessment of Emphysema Using 1.5T MRI With UTE Pulse Sequences
Emphysema is a major pathological feature of Chronic Obstructive Pulmonary Disease (COPD). Non-invasive assessment of emphysema is a crucial issue for the phenotype and follow-up of COPD patients.
- Trial name
- EMPHYREM (NCT02100800)
- Testing
- MR and CT measurements of emphysema quantification
- Where
- France
- Volunteers
- 33 people
- Sponsor
- University Hospital, Bordeaux
Chronic Obstructive Pulmonary Disease
Biomarkers in Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality worldwide and is characterized by fixed airflow obstruction.
- Trial name
- NCT01145300
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Leiden University Medical Center
COPD
Physiotherapy in Patients With Stable Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is a lung disease that is characterized by incompletely reversible airflow obstruction. It is projected to be the fifth leading burden of disease worldwide by the year 2020.
- Trial name
- NCT02517411
- Testing
- Standard care, Physiotherapy added to standard care
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
Pulmonary Disease, Chronic Obstructive
A Clinical Trial of TQC3721 Suspension for Inhalation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
To evaluate the efficacy and safety of TQC3721 Suspension for Inhalation in patients with moderate to severe Chronic obstructive pulmonary disease (COPD)
- Trial name
- NCT06527144
- Testing
- 3mg TQC3721 Suspension for Inhalation, 6mg TQC3721 Suspension for Inhalation
- Where
- 28 sites in China
- Volunteers
- 240 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Asthma, Chronic Obstructive Pulmonary Disease
PK of BDP/FF/GB Single-inhaler Triple Therapy in Japanese vs. Caucasians
The purpose of conducting this study is to obtain PK data of Beclometasone Dipropionate (BDP)/Beclometasone-17-MonoPropionate (B17MP), Formoterol Fumarate (FF) and Glycopyrronium Bromide (GB) after inhalation of CHF 5993 in…
- Trial name
- NCT03859414
- Testing
- Therapeutic Dose 1, Therapeutic Dose 2, Supra-therapeutic Dose
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
COPD
Study of Chronic Obstructive Pulmonary Disease (COPD) Exacerbations In Spain
ECOS is a cross-sectional, observational, longitudinal, multicenter study enrolling 100-200 patients during a COPD exacerbation.
- Trial name
- ECOS (NCT01750658)
- Where
- Spain
- Volunteers
- 99 people
- Sponsor
- Cimera
Implementation of a Chronic Disease Management Programme, COPD
Effects of an Active Implementation of a Guideline for Chronic Obstructive Pulmonary Disease
Aims: To design a proactive implementation strategy for a chronic-disease-management-programme. To describe effects of the active implementation of a programme for COPD-patients measured on patient-related goals and use of health…
- Trial name
- NCT01228708
- Testing
- Active implementation of a guideline for chronic disease
- Volunteers
- 3,021 people
- Sponsor
- University of Aarhus
Cough
An Investigation Into the Mechanism of Inhalation Cough Challenge
Despite its commonplace use in respiratory medicine the mechanism whereby inhalation challenge with a variety of mild acid aerosols produces a dose related and predictable cough is unknown.
- Trial name
- NCT02039999
- Testing
- Nebulised citric acid in serial dilutions, Nebulised ATP solution in serial dilutions, Nebulised TRPA1 agonist solution in serial dilutions
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
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