Clinical trials: Pulmonary Disease, Chronic Obstructive (COPD)
Chronic Obstructive Pulmonary Disease
Anti-inflammatory Effects of Caffeine in Chronic Obstructive Pulmonary Disease (COPD) Subjects
Nowadays it has become evident that a chronic systemic inflammation is present in patients suffering from chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00826566
- Testing
- Caffeine
- Where
- Netherlands
- Sponsor
- Maastricht University Medical Center
COPD (Chronic Obstructive Pulmonary Disease)
Inhaler Training to Enhance Nurses' Competency in Patient Inhaler Education
Nurses play a pivotal role in assessing, educating, and regularly reviewing patients' inhaler techniques. However, inadequate knowledge and skills among nurses can hinder their ability to accurately assess patients' inhaler…
- Trial name
- NCT07527455
- Testing
- Theory-based inhaler training, Usual training
- Volunteers
- 82 people
- Sponsor
- Hong Kong Metropolitan University
Chronic Obstructive Pulmonary Disease
Phase 4 COPD and Suboptimal Inspiratory Flow Rate
Study is a randomized, double-blind, double-dummy, parallel-group study evaluating efficacy and safety of revefenacin vs. tiotropium in adults with severe to very severe COPD and suboptimal PIFR.
- Trial name
- PIFR-2 (NCT05165485)
- Testing
- Revefenacin, Tiotropium
- Where
- 76 sites in United States
- Volunteers
- 404 people
- Sponsor
- Theravance Biopharma
COPD, Osa Syndrome
Screening and Early Warning of Chronic Obstructive Pulmonary Disease Combined With Sleep Respiratory Disease Based on Medical Internet of Things
Chronic obstructive pulmonary disease (COPD) is a common disease that endangers people's health, causing severe economic and treatment burdens.
- Trial name
- NCT04833725
- Testing
- wearable devices
- Where
- China
- Volunteers
- 680 people
- Sponsor
- Peking University Third Hospital
COPD
Home-based Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease
This project aims to assess the short-term effectiveness and responsiveness of a home-based pulmonary rehabilitation (PR) program (reabilitAR) in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT04722224
- Testing
- Home-based pulmonary rehabilitation
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Polytechnic Institute of Porto
COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection
Impact of Switching COPD Patients From Inhaler Devices to the Omron C28P Nebuliser.
The cornerstone of COPD therapy is based on the use of inhalation drugs. The correct use of devices is crucial; a suboptimal use technique is the cause of a possible clinical deterioration with a consequent increase in…
- Trial name
- OMRON (NCT06061679)
- Testing
- Omron C28P nebuliser
- Volunteers
- 99 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Neuromuscular Electrical Stimulation as an Adjunct to Exercise Training in Stable Chronic Obstructive Pulmonary Disease (COPD)
Skeletal muscle dysfunction impairs exercise capacity, quality of life and prognosis in chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT01658046
- Testing
- Neuromuscular electrical stimulation, Endurance training, Quadriceps strength training
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Hacettepe University
COPD Exacerbation
Early Assisted Discharge for COPD Exacerbations With Telemonitoring.
To determine if an early assisted discharge program for acute exacerbations of COPD (AECOPD), with telemonitoring and telephone control, is equally effective and more efficient in terms of use of health care resources, that a…
- Trial name
- NCT01951261
- Testing
- Telemonitoring and telephone control
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Dr. López Viña
COPD, Lung Cancer
Prevalence of COPD in Our Lung Cancer Population, Compared to Controls
This study will investigate the prevalence of chronic obstructive pulmonary disease (COPD) in patients who are newly diagnosed with lung cancer and compare it to the prevalence of COPD in controls recruited from a smoking…
- Conditions
- COPD, Lung Cancer, Smoking
- Trial name
- NCT02603627
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
A Study to Understand the Accuracy of a New Breathing Device Compared to Standard Testing for Asthma and COPD
The diagnosis of either asthma or chronic obstructive pulmonary disease (COPD) is currently based on a combination of symptoms, different lung tests and sometimes a 'trial by treatment'.
- Trial name
- STARDUST (NCT07253883)
- Testing
- Partial pressure of CO2 during tidal breathing, FENO, Spirometry
- Where
- United Kingdom
- Volunteers
- 1,200 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
COPD, Cognitive Impairment
Investigation of Square Step Exercise Applied by Telerehabilitation in Chronic Obstructive Pulmonary Disease Patients
COPD is a progressive disease associated with systemic inflammation, with many extrapulmonary outcomes such as cognitive impairment.
- Conditions
- COPD, Cognitive Impairment, Balance; Distorted
- Trial name
- COPD (NCT04841005)
- Testing
- The Square-Step Exercise Training, Strengthening Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Abant Izzet Baysal University
COPD, Smoking
Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS
The purpose of this randomized study is to demonstrate direct clinical benefit, i.e., observed benefits in how humans with COPD feel in terms of symptoms (e.g., cough frequency, shortness of breath, and other respiratory…
- Conditions
- COPD, Smoking, Tobacco Use
- Trial name
- NCT07108166
- Testing
- Cigarette, THS
- Where
- 112 sites in United States, Bulgaria and 7 more
- Volunteers
- 290 people
- Sponsor
- Philip Morris Products S.A.
Pulmonary Disease, Chronic Obstructive
Bronchial Infection in Patients With COPD and Frequent Exacerbations.
Hypothesis: 1. Innate immunity is altered in certain patients with COPD and frequent exacerbations, a fact that makes them more susceptible to being infected by bacteria. 2.
- Trial name
- NCT03259022
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Chronic Obstructive Pulmonary Disease, Emphysema
Belimumab Treatment of Emphysema Patients With Anti-GRP78 Autoantibodies
This is intended to be an initial "proof-of-concept" study to show feasibility, validate assays and approaches, and explore dosing and safety of belimumab in pulmonary emphysema patients who have clinically relevant (and…
- Trial name
- BOTEGA (NCT03244059)
- Testing
- Belimumab
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Alabama at Birmingham
Chronic Obstructive Pulmonary Disease
Indacaterol Versus Tiotropium on Dynamic Hyperinflation in COPD
Exercise intolerance is a major complain of patients with chronic obstructive pulmonary disease (COPD). Dynamic hyperinflation has been recognized as an important limiting factor responsible for the appearance of intolerable…
- Trial name
- NCT01693003
- Testing
- Indacaterol, Tiotropium
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Irmandade Santa Casa de Misericórdia de Porto Alegre
Chronic Obstructive Pulmonary Disease
Effects of an Air Purifying Device (PureNight) on Sleep Quality in Obstructive Lung Disease
Many individuals with chronic lung disease have night time symptoms that disrupt their sleep. The purpose of this study is to determine the effects of an air purifying device (PureNight, Halo Innovations, Minneapolis, MN) on…
- Trial name
- NCT01772342
- Testing
- HEPA filtration
- Volunteers
- 50 people
- Sponsor
- VA New York Harbor Healthcare System
COPD, Pulmonary Hypertension
An Open-Label Study to Evaluate the Safety and Efficacy of PRX-08066 in Patients With Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease
A 3-month open label study to evaluate the safety and efficacy of PRX-08066 in patients with pulmonary hypertension and COPD.
- Trial name
- NCT00677872
- Testing
- PRX-08066
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Epix Pharmaceuticals, Inc.
COPD, Comorbidities and Coexisting Conditions
Managing Appropriate Prescribing in COPD
Objective: Reducing inappropriate medications for primary care COPD patients with comorbidities ('medication-comorbidity clashes'), by evaluation of the Desktop Helper (number 10) in a pragmatic cluster randomized controlled…
- Trial name
- NCT04539457
- Testing
- Desktop helper, E-learning
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- General Practitioners Research Institute
Healthy Subjects, Chronic Obstructive Pulmonary Disease
Multicenter Study of Impulse Oscillometry in Chinese
The purpose of this study is to establish the reference values of impulse oscillometry (IOS) in healthy Chinese, and compare the indices of IOS in patients with lung disease, such as chronic obstructive pulmonary disease (COPD)…
- Conditions
- Healthy Subjects, Chronic Obstructive Pulmonary Disease, Asthma, Interstitial Lung Disease
- Trial name
- NCT03467880
- Testing
- Clinical Observation
- Where
- 2 sites in China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Chronic Obstructive Pulmonary Disease (COPD)
COPD Treatment by Transplantation of Autologous Bronchial Basal Cells
Chronic obstructive pulmonary disease (COPD) is a group of disease characterized by obstructed airflow. Usually, the lung structure is gradually impaired along with the progression of the disease.
- Trial name
- NCT05594303
- Testing
- Autologuos transplantation of bronchial basal cells
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
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