Clinical trials: Pulmonary Disease, Chronic Obstructive (COPD)
COPD Exacerbation
Extracorporeal CO2 Removal in COPD Exacerbation
The minimally invasive extracorporeal carbon dioxide removal may decrease the respiratory load during chronic obstructive pulmonary disease (COPD) exacerbation, reducing the need to advance the respiratory care toward invasive…
- Trial name
- DECOPD (NCT01422681)
- Testing
- minimally invasive extracorporeal carbon dioxide removal
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
COPD
Long-term Activity Coaching in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality and morbidity around the world. Studies revealed that patients with COPD are less active than age-matched healthy controls and activity level decreases…
- Trial name
- NCT04139200
- Testing
- Type 1 physical activity tele coaching intervention, Type 2 physical activity tele coaching intervention
- Where
- 2 sites in Belgium
- Volunteers
- 150 people
- Sponsor
- KU Leuven
Pulmonary Disease, Chronic Obstructive
COPD MSA 3 Regions: Epidemiology and Risk Factors of COPD in Rural Environment (BM3R)
The agricultural environment presents a unique profile in terms of epidemiology of pulmonary diseases. Certainly due to persistent exposure to organic particles, the prevalence of COPD is higher in farmers than in the general…
- Trial name
- BM3R (NCT03299907)
- Testing
- Spirometry
- Volunteers
- 5,263 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
COPD, Emphysema
Tiotropium Induced Bronchodilation in Lung CT Scored Emphysema
To evaluate if tiotropium (Spiriva)induced bronchodilation of inspiratory capacity in patients with moderate to severe copd subjected to metronome paced hyperventilation induced dynamic hyperinflation is dependent upon the extent…
- Trial name
- NCT00570544
- Testing
- tiotropium
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Gelb, Arthur F., M.D.
COPD Exacerbation, Bronchiectasis With Acute Exacerbation
Multi-omics Studies of Host-microbiome Interaction in Chronic Obstructive Pulmonary Disease and Bronchiectasis
Chronic obstructive pulmonary disease (COPD) and bronchiectasis are common chronic respiratory diseases in China. COPD is characterized by irreversible lung function decline due to airway inflammation, emphysema and alveolar…
- Trial name
- NCT05738044
- Testing
- No intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
Pulmonary Disease, Chronic Obstructive
Inhaled Corticosteroid Withdrawal in Patients With Chronic Obstructive Pulmonary Disease
This is a randomised study to be conducted in patients with severe to very severe Chronic Obstructive Pulmonary Disease (COPD) to establish whether there is a need for these patients to be continuously treated with an inhaled…
- Trial name
- NCT00975195
- Testing
- tiotropium inhalation, salmeterol xinafoate, fluticasone propionate
- Where
- 222 sites in Australia, Belgium and 21 more
- Volunteers
- 2,488 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Evaluation in Individuals with COPD and Asymptomatic Individuals
The literature does not provide sufficient information on the evaluation of frailty, handgrip strength, physical activity, kinesiophobia, and fatigue in elderly individuals with Chronic Obstructive Pulmonary Disease and…
- Trial name
- NCT06077357
- Testing
- MMSE Test, PASE Test, The PRISMA-7 Frailty Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Chronic Obstructive Pulmonary Disease, Sleep Disorders
The Impact of Salmeterol-Fluticasone on Sleep in Patients With COPD
The purpose of this study is to determine if Advair Diskus improves sleep quality by reducing lung hyperinflation in COPD.
- Trial name
- AQuOS-COPD (NCT00741767)
- Testing
- salmeterol-fluticasone
- Where
- United States
- Sponsor
- Northwestern University
Hospital Radmission for COPD Patients
Predictors of Hospital Readmission for Chronic Obstructive Pulmonary Disease Patients
This study is aimed to determine the risk factors for hospital readmission within 6 months in COPD patients
- Trial name
- NCT06348966
- Volunteers
- 188 people
- Sponsor
- Assiut University
COPD
Effects of Low-Dose Theophylline During Chronic Obstructive Pulmonary Disease (COPD) Exacerbations
Molecular mechanisms of COPD exacerbations and the modulating effect of low dose theophylline on that inflammation are elucidated in this project.
- Trial name
- NCT00671151
- Testing
- Theophylline
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Son Dureta
Pulmonary Disease, Chronic Obstructive
Combined Bronchodilators in Chronic Obstructive Pulmonary Disease and the Risk of Adverse Cardio-pulmonary Events
Background: Recent observational studies have reported possible arrhythmogenic effects with long-acting beta-agonists (LABA), while the long-acting anticholinergic tiotropium has been associated with cardiovascular and…
- Trial name
- NCT02096731
- Where
- Canada
- Volunteers
- 115,397 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease (COPD)
Hyperoxia During Outpatient Pulmonary Rehabilitation in Chronic Lung Disease - Does it Matter?
Chronic obstructive pulmonary disease (COPD) is a global burden. Treatment options have improved in recent years, pulmonary rehabilitation plays a key role.
- Trial name
- NCT06776731
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Eastern Switzerland University of Applied Sciences
Pulmonary Disease, Chronic Obstructive
Respimat® Combivent Trial in Chronic Obstructive Pulmonary Disease (COPD)
The primary objective of this study is to compare the effect of ipratropium bromide/salbutamol inhalation spray combination administered by the Respimat® inhaler (20 mcg/100 mcg), ipratropium bromide inhalation spray administered…
- Trial name
- NCT00400153
- Testing
- Atrovent Respimat (20 mcg), COMBIVENT MDI (36/206 mcg), Combivent Respimat (20 mcg/100 mcg)
- Where
- 180 sites in United States, Argentina and 11 more
- Volunteers
- 1,480 people
- Sponsor
- Boehringer Ingelheim
Pulmonary Disease, Chronic Obstructive
Changes in Health and Functional Status in Patients With Chronic Obstructive Pulmonary Disease During Therapy With Spiolto® Respimat® (AERIAL®)
The objective of this NIS is to measure changes in health status including functional status using CCQ scores in COPD patients receiving treatment with Spiolto® Respimat® according to label after approximately 6 weeks in routine…
- Trial name
- NCT03165045
- Testing
- Spiolto® Respimat®
- Where
- 108 sites in Germany
- Volunteers
- 1,351 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease, COPD
Efficacy and Safety Study of Formoterol/Fluticasone and Salmeterol/Fluticasone in Patients With Moderate-to-severe COPD
A study multicenter, phase III, randomized, open label study to evaluate the efficacy and safety of a fixed-dose combination of formoterol/fluticasone and salmeterol/fluticasone in patients with moderate-to-severe chronic…
- Trial name
- NCT01393145
- Testing
- Combination Fluticasone /Formoterol 12/250 μg, Seretide Diskus (salmeterol/fluticasone) 50/250 μg
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Back Pain, Coronary Artery Disease
Detecting and Addressing Preclinical Disability
The Physical Functioning Inventory (PFI) is a standardized patient reported outcome measure that assesses preclinical disability.
- Conditions
- Back Pain, Coronary Artery Disease, Chronic Obstructive Pulmonary Disease, Diabetes
- Trial name
- NCT01979081
- Testing
- Tailored advice from a physiotherapist and/or an occupational therapist through the myOSCAR patient portal
- Where
- Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- McMaster University
COPD
Effects of Ergometer Training With Telemonitoring in Patients With Chronic Obstructive Pulmonary Disease (COPD) After Exacerbation
Home ergometer training combined with online monitoring and regular telephone support could prove to be a cost-effective method to improve physical performance and quality of life in COPD patients.
- Trial name
- COPD (NCT01987544)
- Testing
- Ergometer Training, Motivation
- Where
- Germany
- Volunteers
- 53 people
- Sponsor
- Institut für Pneumologie Hagen Ambrock eV
COPD, Periodontitis
Oral Health and Severe COPD
This case-control study aims to investigate the association of severe COPD with oral health.
- Conditions
- COPD, Periodontitis, Caries, Quality of Life
- Trial name
- NCT05311657
- Where
- Germany
- Volunteers
- 104 people
- Sponsor
- Heidelberg University
Emphysema, Chronic Obstructive Pulmonary Disease
EUROPT Clinical Trial to Study the Efficacy of One-Way Valve Implantation (New Treatment Algorithm) in Patients With Heterogeneous Emphysema
The purpose of this study is to assess the efficacy of a new treatment algorithm for bronchoscopic lung volume reduction (BLVR) in patients with emphysema based on the information of emphysema heterogeneity, destruction score…
- Trial name
- EUROPT (NCT00730301)
- Testing
- Bronchoscopic Lung Volume Reduction (BLVR)
- Where
- 3 sites in Austria, Belgium
- Volunteers
- 20 people
- Sponsor
- LudwLudwig Boltzmann Institute for COPD and Respiratory Epidemiology
COPD
'Real Life' Monitoring of COPD no ICS Patients
The aim of the study will be to assess in patients with mild-to-moderate COPD the role of inflammation in the patient's therapeutic management and follow-up.
- Trial name
- COPDnoICS (NCT05795712)
- Testing
- Therapy Change from Baseline
- Where
- Italy
- Volunteers
- 53 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
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