Clinical trials: Pulmonary Disease, Chronic Obstructive (COPD)
Hypoxia, COPD
Intelligent Oxygen Therapy During Activities of Daily Living
The aim of this study is to assess whether an auto-titrating oxygen system can maintain constant oxygen saturations (SpO2) in patients who are on long-term oxygen therapy (LTOT) during activities of daily living.
- Conditions
- Hypoxia, COPD, Hyperoxia
- Trial name
- NCT02683486
- Testing
- Intelligent oxygen therapy (an auto-titrating oxygen system), Long-term oxygen therapy
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Imperial College London
Chronic Obstructive Pulmonary Disease
Pain Assessment in Patients With Chronic Obstructive Pulmonary Disease (COPD) Exacerbations.
The prevalence of chronic obstructive pulmonary disease (COPD) is between 8 and 12% of the adult population. This prevalence is expected to increase over the coming decades due to the aging of the population and the continued…
- Trial name
- MorphoCOPD1b (NCT03102970)
- Where
- 2 sites in Canada, France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Grenoble
COPD (Chronic Obstructive Pulmonary Disease)
A Study to Investigate the Biomarkers of Hemay005 in Adult Participants With Moderate to Severe COPD
A Multicenter, Randomized, Double-blind, Single-dummy, positive drug and placebo-controlled, Parallel Group, Phase 2a Study to Evaluate the Efficacy and Safety of Hemay005 in Adults with Moderate to Severe Chronic Obstructive…
- Trial name
- NCT07314242
- Testing
- Hemay005 tablets, Roflumilast Oral Tablet
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Ganzhou Hemay Pharmaceutical Co., Ltd
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Obstructive Airways Diseases in Emergency Department (OADED) Study
This is an observational study which aims to evaluate the possibility of using data from a capnography device to assess obstructive airway severity in both Chronic Obstructive Pulmonary Disease (COPD) and Asthma patients.
- Trial name
- NCT02805127
- Volunteers
- 12 people
- Sponsor
- Oridion
Pulmonary Disease, Chronic Obstructive
A Wearable and a Self-management Application for Chronic Obstructive Pulmonary Disease (COPD) Patients at Home
Our overall research goal for this project is to create a wearable device and mobile application, appealing to patients with Chronic Obstructive Pulmonary Disease (COPD), which provides them with appropriate self-management tools…
- Trial name
- COPDwear (NCT03857061)
- Testing
- smartphone, smartwatch, WearCOPDv2 application
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Chronic Obstructive Pulmonary Disease
Wireless Assessment of Respiratory and Circulatory Distress in Chronic Obstructive Pulmonary Disease - Validation Study
For patients admitted to the medical ward, it is often difficult to predict if their clinical condition will deteriorate, however subtle changes in vital signs are usually present 8 to 24 hours before a life-threatening event…
- Trial name
- NCT04248842
- Testing
- Continuous monitoring system
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
T Lymphocyte Cells in Individuals Experiencing an Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine whether the lungs of individuals with chronic obstructive pulmonary disease (COPD) contain resident memory T lymphocytes that can produce a combination of cytokines that induce the…
- Trial name
- NCT00281229
- Where
- 2 sites in United States
- Volunteers
- 481 people
- Sponsor
- University of Michigan
Inflamation, COPD
Inflammation and Oxidative Stress in COPD
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide, characterized by persistent airflow limitation, chronic inflammation, and increased oxidative stress.
- Conditions
- Inflamation, COPD, Oxidative Stress, Pulmonary Rehabilitation
- Trial name
- NCT07376161
- Testing
- Pulmonary Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Esra Yazar
COPD
Adipose Derived Stem Cells Transplantation for Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is the name for a collection of lung diseases including chronic bronchitis, emphysema and chronic obstructive airways disease.
- Trial name
- NCT02645305
- Testing
- Adipose derived stem cells
- Where
- 3 sites in Vietnam
- Volunteers
- 20 people
- Sponsor
- University of Science Ho Chi Minh City
Chronic Obstructive Pulmonary Disease
Baduanjin Exercise for Patients With GOLD 2-3 Stable COPD on Pulmonary Rehabilitation
Chronic Obstructive Pulmonary Disease (COPD) is a disease with a very high morbidity and mortality rate. When the lung function drops lower and lower, patients will bear great affliction physically and mentally.
- Trial name
- NCT03892629
- Testing
- Baduanjin exercise, Instrument rehabilitation
- Where
- China
- Volunteers
- 240 people
- Sponsor
- ShuGuang Hospital
Chronic Obstructive Pulmonary Disease
A Study to Evaluate the Efficacy and Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
This study will evaluate the efficacy, safety, and pharmacokinetics of astegolimab in combination with standard of care chronic obstructive pulmonary disease (COPD) maintenance therapy in patients with COPD who are former or…
- Trial name
- NCT05037929
- Testing
- Astegolimab
- Where
- 193 sites in United States, Argentina and 22 more
- Volunteers
- 1,334 people
- Sponsor
- Genentech, Inc.
Chronic Obstructive Pulmonary Disease
Efficacy and Safety of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This study was designed to provide 12 weeks efficacy and safety data of the 150 μg once-daily (od) dose of indacaterol in chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00624286
- Testing
- Indacaterol 150 μg
- Where
- 120 sites in United States, Belgium and 1 more
- Volunteers
- 416 people
- Sponsor
- Novartis
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Safety of Indacaterol in Adults (40 Years and Above) With Chronic Obstructive Pulmonary Disease (COPD)
This study evaluated the efficacy and safety of two doses of indacaterol in adults aged 40 or over with chronic obstructive pulmonary disease (COPD) in China and in two other countries.
- Trial name
- NCT00792805
- Testing
- Indacaterol 150 µg, Indacaterol 300 μg
- Where
- 15 sites in Australia, China and 1 more
- Volunteers
- 563 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease
Difference in the Metabolic Characteristics of COPD Patients and Healthy Adults
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04046666
- Testing
- Functional near infrared spectroscopy, Moxibustion
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
COPD
Effects of Low-Dose Theophylline During Chronic Obstructive Pulmonary Disease (COPD) Exacerbations
Molecular mechanisms of COPD exacerbations and the modulating effect of low dose theophylline on that inflammation are elucidated in this project.
- Trial name
- NCT00671151
- Testing
- Theophylline
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Son Dureta
COPD
Objective Assessment of Adherence to Inhalers by COPD Patients
Rationale: Objective adherence to inhaled therapy by patients with chronic obstructive pulmonary disease (COPD) has not been reported.
- Trial name
- NCT04025242
- Volunteers
- 244 people
- Sponsor
- Beaumont Hospital
Infection, Heart Failure
Prediction of Patient Deterioration Using Machine Learning
This is a retrospective observational study drawing on data from the Brigham and Women's Home Hospital database. Sociodemographic and clinic data from a training cohort were used to train a machine learning algorithm to predict…
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT05045742
- Testing
- Traditional vital sign alarms versus the BioVitals Index vs the National Early Warning Score 2
- Where
- 2 sites in United States
- Volunteers
- 526 people
- Sponsor
- Brigham and Women's Hospital
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Biomarker Study
Chronic Obstructive Pulmonary Disease (COPD) is a progressive disease that is characterized by loss of lung function, leading to breathlessness, poor quality of life, loss in productivity, and increased mortality.
- Trial name
- NCT02050022
- Where
- Canada
- Volunteers
- 522 people
- Sponsor
- University of British Columbia
Chronic Obstructive Pulmonary Disease
A Descriptive Study to Explore Certain Characteristics of Patients at Risk for Chronic Obstructive Pulmonary Disease (COPD) in a Primary Care Setting
The purpose of this study is to explore if certain characteristics, easily detected within a regular primary care setting, may indicate that a patient at risk for COPD (45 ≤ age ≤ 80 years and a smoking history of ≥ 15 pack…
- Trial name
- NCT01013922
- Where
- 23 sites in Sweden
- Volunteers
- 309 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
sTep dOWn Inhalers in the reAl woRlD
To establish the feasibility of stopping inhaled steroids and switching or maintaining dual bronchodilation in one visit - in the real world, for people with COPD.
- Trial name
- TOWARD (NCT03527927)
- Testing
- Any LABA/LAMA
- Where
- United Kingdom
- Volunteers
- 67 people
- Sponsor
- Hywel Dda Health Board
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