Clinical trials: Pulmonary Disease, Obstructive
Bronchiolitis Obliterans Syndrome
Imaging and Understanding BOS in Lung Transplantation
This study is a prospective, non-randomized, longitudinal, observational study that will recruit about 5 lung transplant patients per year for 3 years.
- Trial name
- NCT02316392
- Testing
- Hyperpolarized Helium-3 MRI
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
COPD
Biannual Review of Exhaled Air and Trends in Health Evaluation in COPD
This study aims to evaluate how airway inflammation, lung function, and symptoms change over time in people with chronic obstructive pulmonary disease (COPD).
- Trial name
- BREATHE-COPD (NCT07045948)
- Testing
- Blood eosinophil Count
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Chronic Obstructive Pulmonary Disease
COPD Assessment and Management Bundle Versus Usual Care
Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory (lung) disease that makes it harder to breathe over time.
- Trial name
- NCT01833026
- Testing
- Spirometry test, Levalbuterol
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Illinois Chicago
Chronic Obstructive Pulmonary Disease
A Clinical Trial of TQC3721 Suspension for Inhalation
To evaluate the safety, tolerability and pharmacokinetic characteristics of TQC3721 suspension for inhalation in single/multiple administration(s) in healthy subjects; to evaluate the safety,tolerability and efficacy TQC3721…
- Trial name
- NCT05051930
- Testing
- TQC3721 suspension for inhalation
- Where
- China
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Chronic Obstructive Pulmonary Disease
A RESearch on the PrEvalence and the Diagnosis of COPD and Its Tobacco-related Etiology
The aim of the RESPECT study is to gain a better understanding of the prevalence, pathogenesis and symptoms of early chronic obstructive pulmonary disease (COPD).
- Trial name
- RESPECT (NCT02307799)
- Where
- 2 sites in Russia
- Volunteers
- 3,133 people
- Sponsor
- Université Catholique de Louvain
Chronic Obstructive Pulmonary Disease
CLEAR Model for Predicting Ventilatory Liberation in Severe COPD
This prospective observational cohort study aims to prospectively evaluate and validate the Clinical Load, Exchange, Ability of Respiration, and Reserve (CLEAR) model for predicting sustained ventilatory liberation in patients…
- Trial name
- CLEAR (NCT07579052)
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Assiut University
Covid-19, Asthma
COVID-19 Related Lung Ventilation and Perfusion Injury
Little is currently known about the immediate and long-term effect of COVID-19 on lung ventilation (delivery of air to the lungs) and lung perfusion (delivery of blood to the lungs).
- Conditions
- Covid-19, Asthma, Healthy
- Trial name
- NCT04549636
- Testing
- V/Q SPECT-CT, St. George's Respiratory Questionnaire (SGRQ), mMRC (Modified Medical Research Council) Dyspnea Scale
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- McMaster University
Asthma
Evaluation of the Relapse Rate One Month After Discharge From Emergency Department for Asthmatic Patients Given a Strict Formalized Follow up Protocol
For over ten years, the French group ASUR (ASthme aux URgences) has studied the asthmatic disease. The first epidemiological study enrolling 3.772 patients, in 39 emergency services, showed that the treatment protocols during the…
- Trial name
- ASUR-R (NCT02424409)
- Testing
- 2: Intervention, 1: Control
- Where
- France
- Volunteers
- 1,422 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma, Education, Medical
Evaluating a Pediatric Asthma Management Education Program for Physicians
Inhaled corticosteroids taken on a daily basis have been proven to be the most effective treatment for children with persistent asthma.
- Trial name
- NCT00399984
- Testing
- Asthma Education Program
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Bronchial Asthma
The Registration on the Use of Feilike Heji in Minors
Feilike HeJi is produced by Guizhou Jianxing Pharmaceutical Co. LTD. For the treatment of phlegm heat caused by lung cough phlegm yellow, bronchial asthma, bronchitis, see the syndrome of proprietary Chinese medicine (approval…
- Trial name
- NCT04658992
- Where
- 21 sites in China
- Volunteers
- 3,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Pulmonary Disease, Chronic Obstructive
The Development, Implementation and Evaluation of Clinical Pathways for Chronic Obstructive Pulmonary Disease (COPD) in Saskatchewan
Chronic obstructive pulmonary disease (COPD) has substantial economic and human costs. To minimize these costs high quality guidelines have been developed.
- Trial name
- NCT03075709
- Testing
- Clinical Pathway (CPW)
- Where
- Canada
- Volunteers
- 800 people
- Sponsor
- University of Saskatchewan
Asthma Control
A Study Assessing the Effect of Dupilumab on Inducing Clinical Remission in Asthma
This study tests whether an asthma medication called dupilumab can help people achieve complete asthma control (called "remission") when given earlier in their disease, before asthma becomes severe.
- Trial name
- HOTHOT (NCT07309614)
- Testing
- Dupilumab Prefilled Syringe
- Where
- 5 sites in Australia, Canada and 1 more
- Volunteers
- 150 people
- Sponsor
- Université de Sherbrooke
Asthma
Comparing Bronchodilation of Symbicort With and Without Valved Holding Chamber (Aerochamber Plus)
This study will compare the amount of bronchial tube relaxation from the Formoterol medicine contained in the Symbicort pressure Metered Dose Inhaler(pMDI)(a combination of Budesonide, a steroid, and Formoterol, a drug which…
- Trial name
- WSMR2 (NCT00915538)
- Testing
- pMDI budesonide/formotrol 160/4.5 is in group 1, Symbicort 160/4.5 plus Aerochamber Plus included in group 2
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Western Sky Medical Research
Asthma
Single and Multiple Ascending Dose Study of TD-8236 by Inhalation
This is a Phase 1, randomized, double-blinded, placebo controlled study. The study consists of 3 parts: Part A is a single ascending dose (SAD) study in healthy subjects, Part B is a multiple ascending dose (MAD) study in…
- Trial name
- NCT03652038
- Testing
- TD-8236
- Where
- 2 sites in United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
COPD - Chronic Obstructive Pulmonary Disease, Healty Controls
Hemodynamic Responses and Brain Activity During Dual Tasks in COPD Patients Versus Healthy Individuals
Abstract Cognitive dysfunction is joint in patients with chronic obstructive pulmonary disease (COPD). In particular, there are effects in tasks that require attention, executive functions, and working memory related to the…
- Trial name
- NCT06974448
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Bronchiolitis, Viral
High Flow Oxygen Therapy vs Standard Care in Infants With Viral Bronchiolitis
A randomized control trial of 130 infants admitted to the paediatric high care admission ward will be enrolled, and randomized to either "high flow humidified oxygen" or "standard therapy".
- Trial name
- NCT03252119
- Testing
- High flow humidified oxygen therapy
- Where
- South Africa
- Volunteers
- 28 people
- Sponsor
- Chris Hani Baragwanath Academic Hospital
Chronic Obstructive Pulmonary Disease
Bufei Jianpi Granule for Delaying Pulmonary Function Decline in Early-Stage COPD
This study aims to establish the treatment scheme of Bufei Jianpi granule for early-stage (GOLD stage 1 or 2) chronic obstructive pulmonary disease (COPD), delaying pulmonary function decline and forming high quality evidence.
- Trial name
- NCT03976700
- Testing
- Bufei Jianpi granule
- Where
- China
- Volunteers
- 612 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
A Study to Evaluate the Integrated Dose Counter on an Albuterol Hydrofluoroalkane (HFA) Metered Dose Inhaler (MDI)
This study is evaluating the effectiveness of a dose counter for an inhaler device used to deliver medication to people diagnosed with asthma or COPD.
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Emphysema, Chronic Bronchitis
- Trial name
- NCT01302587
- Testing
- Albuterol
- Where
- 25 sites in United States
- Volunteers
- 306 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Bronchial Asthma
Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose ,With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.
Many studies have investigated the efficacy and safety of Intravenous magnesium sulfate and inhaled steroids in addition to the standard treatment for patients with severe asthma attacks.
- Trial name
- NCT02455687
- Testing
- Hi-dose iv MgSO4, Nebulized budesonide, Std-dose iv MgSO4
- Where
- Qatar
- Volunteers
- 240 people
- Sponsor
- Hamad Medical Corporation
Chronic Obstructive Pulmonary Disease, Multiple Comorbidity
Program of Integrated Care for Patients With Chronic Obstructive Pulmonary Disease and Multiple Comorbidities
Many patients with chronic obstructive pulmonary disease (COPD) also have other diseases referred to as comorbidities. Often these patients require health care by a variety of health care professionals from services linked to…
- Trial name
- PICCOPD+ (NCT01648621)
- Testing
- 40 minute standardized education session, Individualized action plan, Individualized care plan
- Where
- 2 sites in Canada
- Volunteers
- 470 people
- Sponsor
- Michael Garron Hospital