Clinical trials: Pulmonary Disease (COPD), Chronic Obstructive
Chronic Obstructive Pulmonary Disease
Bufei Yishen Granule for Reducing Acute Exacerbation in GOLD Stage 3 or 4 COPD
This study aims to establish the treatment scheme of Bufei Yishen granule for GOLD stage 3 or 4 chronic obstructive pulmonary disease (COPD), reducing acute exacerbation, improving exercise capacity and forming high quality…
- Trial name
- NCT03976713
- Testing
- Bufei Yishen granule, Tiotropium Bromide Powder for Inhalation
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Cancer, Liver Cirrhosis
Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
To acquire blood samples from subjects for various purposes, including: i) determining the sensitivity and specificity of select DNA methylation markers for the detection of various types of cancer, ii) identifying benign…
- Conditions
- Cancer, Liver Cirrhosis, Chronic Hepatitis, Hepatitis B
- Trial name
- ELITE (NCT05181826)
- Testing
- Multi-analyte Blood Test
- Where
- 7 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- Helio Genomics
Chronic Obstructive Pulmonary Disease
Comparing Senobi and Jacobsons Exercises in COPD
The study aims to evaluate the effects of Senobi versus Jacobsons muscular relaxation exercises on pulmonary functions, dyspnea, and sleep quality in chronic obstructive pulmonary disease.
- Trial name
- NCT06530043
- Testing
- Senobi exercises, Jacobsons Muscular relaxation exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Tolerability Study in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients
Efficacy and tolerability study in severe chronic obstructive pulmonary disease (COPD) patients.
- Trial name
- SECURE2 (NCT01415518)
- Testing
- Drug: Budesonide/formoterol (Symbicort Turbuhaler, Drug: ipratropium (AtroventTM), theophylline SR
- Where
- 21 sites in China
- Volunteers
- 581 people
- Sponsor
- AstraZeneca
Emphysema, COPD
Zephyr Valve Japan Post-Marketing Surveillance
This is a multicenter, prospective, observational surveillance enrolling 140 consecutive patients with severe emphysema who are candidates for bronchoscopic lung volume reduction using Zephyr Endobronchial Valve at up to 20…
- Conditions
- Emphysema, COPD, Severe Emphysema
- Trial name
- NCT06332885
- Testing
- Zephyr Endobronchial Valve
- Where
- 17 sites in Japan
- Volunteers
- 140 people
- Sponsor
- Pulmonx Corporation
Chronic Obstructive Pulmonary Disease
Effects of an Inpatient Rehabilitation for Patients With Chronic Obstructive Pulmonary Disease (COPD) III/IV
The purpose of this study is to determine if there is a change in the CAT-score after an inpatient rehabilitation of three weeks and if it correlates with other common parameters.
- Trial name
- NCT01418768
- Testing
- inpatient rehabiliation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Pulmonary Disease, Chronic Obstructive
A 24-week Evaluation of GSK573719/Vilanterol (62.5/25mcg) and Components in COPD
This is a phase III multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of GSK573719/GW642444 Inhalation Powder, GSK573719 Inhalation Powder, GW642444 Inhalation…
- Trial name
- DB2113373 (NCT01313650)
- Testing
- 62.5/25mcg, 62.5mcg, 25mcg
- Where
- 165 sites in United States, Bulgaria and 11 more
- Volunteers
- 1,538 people
- Sponsor
- GlaxoSmithKline
Pulmonary Disease，Chronic Obstructive;
Small Airways Evaluation and Treatment
Chronic obstructive pulmonary disease (COPD) is a common disease , and characterized by progressive development of airflow limitation.
- Trial name
- NCT02526758
- Testing
- beclomethasone, formoterol, budesonide
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhujiang Hospital
Chronic Obstructive Pulmonary Disease
Effects Of of Pursed Lip Breathing and Coordinated Breathing in Adult Patients With COPD
COPD is the chronic lung condition characterized by the damage and enlargement of the air sacs in the lungs, leading to breathing difficulties. A blockage may develop, which traps air inside your lungs.
- Trial name
- NCT06459843
- Testing
- pursed lip breathing techniques, coordinated breathing technique
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease
Mesenchymal Stem Cells in the Treatment of Subjects With Advance Chronic Obstructive Pulmonary Disease (COPD)
Researchers are trying to understand the effects of mesenchymal stem cells therapy in subjects with advance chronic obstructive pulmonary disease
- Trial name
- NCT04047810
- Testing
- Mesenchymal Stem Cells
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Cardiovascular Disease, Asthma
Effectiveness of Pollution Monitoring in Clinical Exercise Rehabilitation
The primary objective of EPIC-AIR is to evaluate the feasibility and potential effectiveness of integrating real-time air pollution monitoring into cardiac rehabilitation (CR) and pulmonary rehabilitation (PR) programmes via an…
- Conditions
- Cardiovascular Disease, Asthma, COPD, Interstitial Lung Disease Due to Systemic Disease
- Trial name
- EPIC-AIR (NCT07500948)
- Testing
- Progressive Walking Exercise Programme, Real-time air quality information and guidance
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Chronic Obstructive Pulmonary Disease
Fish Oil and HMB Supplementation in COPD
In the present study, the role of chronic (10 weeks) intake of low dose (2g/day) of EPA+DHA in whole body protein metabolism, and functional performance and systemic inflammation will be examined, and whether adding either HMB at…
- Trial name
- COPD fish oil (NCT03796455)
- Testing
- Capsule + Powder supplementation, stable tracer infusion
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Texas A&M University
Emphysema or COPD
Chartis Collateral Ventilation Measurement: Conscious Sedation Versus General Anesthesia
Rationale: The Chartis® ( Pulmonx, CA, USA) measurement system is a tool to assess interlobar collateral ventilation during bronchoscopy.
- Trial name
- NCT03205826
- Testing
- Type of sedation used
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Asthma, COPD
Acute Exacerbations Treated With BenRAlizumab (The ABRA Study)
Exacerbations of asthma and COPD are an important cause of hospital admission and the main cause of annual winter bed shortages.
- Trial name
- ABRA (NCT04098718)
- Testing
- Benralizumab, Prednisolone
- Where
- United Kingdom
- Volunteers
- 158 people
- Sponsor
- University of Oxford
Chronic Obstructive Pulmonary Disease
Efficacy of Telemetry-assisted Care in Home Home Vented COPD
This study in patients suffering of Chronic Obstructive Pulmonary disease (COPD) aims to investigate whether telemonitoring of their non invasive ventilation (NIV) device together with targeted, tailored intervention in case of…
- Trial name
- TeleInterVENT (NCT05287555)
- Testing
- Telemonitoring Care, Standard Care
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- Georg Nilius, Prof DR med
Proprioceptive Postural Control, Chronic Obstructive Pulmonary Disease
Proprioceptive Postural Control and Chronic Obstructive Pulmonary Disease (COPD)
Proprioceptive weighting changes may explain differences in postural control performance. In addition, the respiratory movement has a disturbing effect on postural balance.
- Trial name
- NCT01505543
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Chronic Obstructive Pulmonary Disease
Assessment of Ventilation-perfusion Abnormalities in Patients With Stable Smoking-related Airways Disease
Subjects undergo history, examination, lung function assessment after informed consent has been obtained. All subjects will undergo ventilation-perfusion scans.
- Trial name
- NCT00180843
- Testing
- salbutamol + ipratropium bromide nebules, nebulized saline
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Imperial College London
Chronic Obstructive Pulmonary Disease
Use of MonitorMe in COPD
MonitorMe is a telephone device intended for the non-critical monitoring of vital signs in a domestic environment with the ability to automatically transmit data to a remote location via basic telephone connectivity.
- Trial name
- NCT04108143
- Testing
- MonitorMe
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Lincoln
Chronic Obstructive Pulmonary Disease
Associations Between Air Pollutants Exposures and Respiratory System Study
Epidemiological investigations has suggested exposure to air pollution linked with respiratory disease, especially chronic obstructive pulmonary disease. However, the potential mechanisms of adverse effects remains scare.
- Trial name
- NCT02964117
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Chronic Obstructive Pulmonary Disease
Effects of Indacaterol in Symptomatic COPD Patients With Low Risk of Exacerbations
This study compared the efficacy of indacaterol versus placebo in COPD patients classified as GOLD 2014 Patient Group B. This was a 2-arm parallel group study that recruited COPD patients classified by GOLD Patient Gorup B.
- Trial name
- NCT02418468
- Testing
- Indacaterol
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- Novartis Pharmaceuticals
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