Clinical trials: Pulmonary Disease (COPD), Chronic Obstructive
Chronic Obstructive Pulmonary Disease
Combined Effect of Scapulothoracic Mobilization With Buteyko Breathing on COPD (Chronic Obstructive Pulmonary Disease) Patients
The objective of this study will be to determine the combine effect of scapulothoracic mobilization with Buteyko breathing on pulmonary parameters functional capacity and balance among COPD patient.
- Trial name
- NCT07106086
- Testing
- Scapulothoracic mobilization, Buteyko breathing
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Rashid Latif Medical College
Chronic Obstructive Pulmonary Disease (COPD)
A Pilot Comparison Study of Vibrating Mesh Versus Standard Jet Nebuliser for Bronchodilator Delivery in COPD
Treatment of chronic obstructive pulmonary disease (COPD) incorporates various modes of inhalation therapy. The response to treatments is dose dependent thus applying the most efficient device to administer the treatment is…
- Trial name
- NCT02686086
- Testing
- vibrating mesh nebuliser, Standard hospital jet nebuliser, Combined salbutamol 2.5 mg and ipratropium 0.5mg nebule
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- Beaumont Hospital
Chronic Obstructive Pulmonary Disease (COPD)
A 12 Week Treatment, Multi-center, Randomized, Double-blind, Parallel-group, Placebo and Active Controlled Study to Assess the Efficacy, Safety, and Tolerability of Indacaterol Maleate / Glycopyrronium Bromide in COPD Patients With Moderate to Severe Airflow Limitation.
This study will assess the efficacy, safety and tolerability of QVA149 in patients with moderate to severe airflow limitation.
- Trial name
- NCT01727141
- Testing
- QVA149, QAB149, NVA237
- Where
- 143 sites in United States, Canada and 6 more
- Volunteers
- 1,042 people
- Sponsor
- Novartis Pharmaceuticals
Pulmonary Disease, Chronic Obstructive
Exploratory Study of Xolair in Chronic Obstructive Pulmonary Disease in Patients With Elevated IgE Levels
The objective is to conduct an exploratory study on the effect of Omalizumab on COPD patients with elevated IgE. Exploratory outcomes include to determine whether Omalizumab use: reduces exacerbations in COPD patients; or…
- Trial name
- NCT00851370
- Testing
- Omalizumab (Xolair)
- Where
- United States
- Sponsor
- National Jewish Health
Anesthesia
The Effect of Sevofluorane on Wash-out Time in COPD
COPD (Chronic obstructive disease ) is a condition of respiratory system failure seen occasionally in elderly patients of society. Sevofluorane is a safe, volatile anesthetic used considerably widely all over the world.
- Trial name
- washout (NCT02209883)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
Dynamic T2 Preparation
Magnet Resonance Imaging to Evaluate of Dynamic T2 Preparation Puls by Patients With Shunt or Chronic Obstructive Pulmonary Disease
There is preliminary evidence that a dynamic T2 Preparations Puls sequence by cardiac magnet resonance imaging can differentiate between oxygenated and deoxygenated blood.
- Trial name
- NCT02449083
- Testing
- MRI, coronary angiography
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Chronic Obstructive Pulmonary Disease
Azithromycin for Acute Exacerbations Requiring Hospitalization
This project (funded by the IWT-TBM program) will organize a randomized placebo-controlled multicenter intervention trial in 500 COPD patients to study the effectiveness and safety of azithromycin therapy in the acute setting of…
- Trial name
- BACE (NCT02135354)
- Testing
- Azithromycin
- Where
- 20 sites in Belgium
- Volunteers
- 301 people
- Sponsor
- Wim Janssens
Chronic Obstructive Pulmonary Disease
Educational Intervention for Managing Inhalers in Chronic Obstructive Pulmonary Disease (COPD) Patients
Given the importance of the correct use of inhalers by patients with Chronic Obstructive Pulmonary Disease (COPD) for the appropriate treatment of the disease, the self-care programme which will be assessed will consist of an…
- Trial name
- NCT01380405
- Testing
- education intervention
- Where
- Spain
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Chronic Obstructive Pulmonary Disease (COPD)
TD-4208 Absorption, Distribution, Metabolism and Excretion (ADME) Study in Healthy Male Subjects
The purpose of this study is to evaluate the absorption, distribution, metabolism and excretion of an investigational medication used to treat chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02772159
- Testing
- TD-4208
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Mylan Inc.
Chronic Obstructive Pulmonary Disease
Multidimensional Individualized Nutritional Therapy for Individuals with Severe COPD
Individuals with severe chronic pulmonary disease often life isolated with a high burden of symptoms. Nutritional risk and low quality of life are common, and both associated with increased societal cost and poor prognosis.
- Trial name
- MINDNUT (NCT04873856)
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Nordsjaellands Hospital
Community Health Nursing Education, Chronic Obstructive Pulmonary Disease
Virtual Reality Cave vs. Simulated Home for Community Nursing Education: A Crossover Trial Comparing Student Competence, Confidence, and Satisfaction
Background and Purpose Community health nursing is essential for providing healthcare to individuals in home and neighborhood settings.
- Conditions
- Community Health Nursing Education, Chronic Obstructive Pulmonary Disease, Pulmonary Tuberculosis
- Trial name
- NCT07595588
- Testing
- VR CAVE Immersive Simulation for Community Health Nursing Education, Traditional Simulated Home Environment for Community Health Nursing Training
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Chronic Obstructive Pulmonary Disease
Combination of NHF and Nebulizer on Lung Function in COPD
This study will prove to concept of effectiveness of NHF in combination with a nebulizer on reversibility of lung function in COPD patients.
- Trial name
- AEROFLOW (NCT02885103)
- Testing
- Nasal high flow (NHF), Nebulizer
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Leipzig
COPD, Motivational Interviewing
Motivational Interview-based Self-management Training
Chronic Obstructive Pulmonary Disease (COPD) is an important chronic disease that causes increasing mortality and morbidity globally, as well as a social and economic burden.
- Conditions
- COPD, Motivational Interviewing, Self Management, Self-Efficacy
- Trial name
- COPD (NCT05054205)
- Testing
- Motivational İnterviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Akdeniz University
Chronic Obstructive Pulmonary Disease, Dyspnea
Breathlessness Exertion and Morphine Sulphate
Breathlessness is an overwhelming symptom affecting tens of thousands of Australians every day. For many people, it persists even when all the underlying causes have been optimally managed (chronic breathlessness).
- Trial name
- BEAMS (NCT02720822)
- Testing
- Morphine Sulfate, Plus laxative (Docusate with senna), FitBit charge HR (Accelerometer)
- Where
- 15 sites in Australia, New Zealand
- Volunteers
- 171 people
- Sponsor
- Flinders University
Chronic Obstructive Pulmonary Disease
Aspergillus and Chronic Obstructive Pulmonary Disease Evolution
This is a prospective multicenter cohort study which includes all consecutive COPD patients who come for a visit in one the participating pneumologist. They will have to do a sputum and to complete some questionnaries.
- Trial name
- AspergBPCO (NCT03646851)
- Testing
- Questionnaries
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pulmonary Disease, Chronic Obstructive
Cardiovascular Function in COPD Patients
The objectives of the study are to explore the effect of treatment with tiotropium + olodaterol fixed dose combination (FDC) compared to fluticasone propionate + salmeterol FDC on: reversal of left ventricular diastolic…
- Trial name
- NCT03055988
- Testing
- Tiotropium, Olodaterol, Fluticasone propionate
- Where
- 10 sites in Germany
- Volunteers
- 76 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Diseases
The Role of Ambulatory Oxygen in Improving the Effectiveness of Pulmonary Rehabilitation for COPD Patients
Pulmonary rehabilitation (PR) is an exercise program tailored for patients with chronic lung disease that is a core part of the management of patients with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT02707770
- Testing
- Pulmonary Rehabilitation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College Healthcare NHS Trust
Chronic Obstructive Pulmonary Disease (COPD)
A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This study is a randomized, double-Blind, placebo-controlled, Single- and Multiple-ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, Pharmacodynamics and Clinical Activity of BBT002 in…
- Trial name
- NCT07288554
- Testing
- BBT002
- Where
- 11 sites in China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Bambusa Therapeutics
Pulmonary Disease, Chronic Obstructive
Genomic/ Proteomic/ Metabonomic Profiling in Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a chronic disease characterized by progressive airflow obstruction, chronic cough and dyspnoea in advanced stages. We hope to develop a better understanding of lung disease.
- Trial name
- NCT00655694
- Testing
- sputum, blood, urine, exhaled breath, lung function
- Where
- United Kingdom
- Sponsor
- Imperial College London
COPD
Personalised Exercise Training in COPD
Exercise training as part of Pulmonary Rehabilitation (PR) has been shown conclusively to improve breathlessness,quality of life and exercise capacity for people with COPD.
- Trial name
- NCT03817294
- Testing
- Comparison of exercise training modalities
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Loughborough University
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