Clinical trials: Pulmonary Disease (COPD), Chronic Obstructive
Chronic Obstructive Pulmonary Disease
Immune Damage and Vaccination in COPD Patients
Better understanding of the specificities of the vaccine response in patients with COPD
- Trial name
- ALTIBPCO (NCT03804138)
- Testing
- Anti-influenza and DTp pertussis vaccinations
- Where
- 2 sites in France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Chronic Obstructive Pulmonary Disease
COPE With COPD Trial
The overall objective of this study is to evaluate a collaborative self-management intervention in patients with moderate to severe COPD in a primary care population.
- Trial name
- NCT02343055
- Testing
- Case Management and Self-Management Education
- Where
- 4 sites in Canada
- Volunteers
- 182 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
HIV Infections, COPD
Prevalence and Determinants of Chronic Obstructive Pulmonary Disease (COPD) in HIV+ Patients
The prevalence of COPD in HIV+ and AIDS patients is unknown. The pathophysiology of HIV infection and COPD might be of interest to both conditions.
- Trial name
- HIV&COPD (NCT00904384)
- Where
- Spain
- Volunteers
- 350 people
- Sponsor
- Cimera
COPD
Evaluation Inhaled Corticosteroids on Exhaled Nitric Oxide Gas Exchange
To evaluate the role of inhaled corticosteroids to suppress nitric oxide gas exchange in stable patients with moderate-to-severe COPD who are current non-smokers and not on oral corticosteroids.
- Trial name
- NCT00568347
- Testing
- fluticasone 100mcg/ salmeterol 50mcg, fluticasone 250/salmeterol 50, salmeterol
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Arthur F Gelb MD
Chronic Obstructive Pulmonary Disease (COPD)
Clinical Trial of Air Cleaners to Improve Indoor Air Quality and COPD Health
Objectives (include all primary and secondary objectives) Specific Aim #1: To determine whether an air cleaner intervention to improve home air quality will improve respiratory symptoms, quality of life, lung function and reduce…
- Trial name
- NCT02236858
- Testing
- HEPA Air Cleaner
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Johns Hopkins University
COPD Exacerbation
Magnesium Sulfate Versus Ipratropuim Bromide in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Treatment with short acting β2 agonists for exacerbations of COPD results in clinical improvement. It has not been established whether combining short acting β2 agonists to other bronchodilators is more effective than β2 agonists…
- Trial name
- NCT01136421
- Testing
- Ipratropium bromide, Magnesium Sulfate
- Where
- 2 sites in Tunisia
- Volunteers
- 124 people
- Sponsor
- University of Monastir
Pulmonary Disease, Chronic Obstructive
12-week Treatment With Inhaled Tiotropium (18 mcg Once Daily) on Lung Function and Static Lung Volumes in Stable, Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Patients. Correlation to Dyspnoea Scales
Determine the effect of 12-week treatment with inhaled tiotropium bromide on lung function and static lung volumes, correlate this effect with dyspnoea in COPD patients.
- Trial name
- NCT02172378
- Testing
- Tiotropium inhalation capsules
- Volunteers
- 116 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Bronchopneumopathy, Infectious Pneumonia
Study of Collagen IV and XIX in Bronchoalveolar Lavage, Pulmonary Aspiration and Bronchial Biopsies
Collagens are proteins present in all tissues. Besides their structural role, recent data showed that they were able to regulate many cellular functions.
- Conditions
- Chronic Obstructive Bronchopneumopathy, Infectious Pneumonia, Pneumonitis, Lung Cancer
- Trial name
- BRONCOLL (NCT02788643)
- Testing
- biological fluids (serum, bronchoalveolar lavage and pulmonary aspiration) and bronchial biopsies collection
- Where
- France
- Volunteers
- 51 people
- Sponsor
- CHU de Reims
Chronic Obstructive Pulmonary Disease
HFNC Effect on BCSS in Patients With COPD
The primary objective of this study is to look for a correlation between the use of high-flow nasal cannula in the outpatient setting in patients with previous chronic obstructive pulmonary disease exacerbation and the change in…
- Trial name
- COPD (NCT02825043)
- Testing
- High-Flow Nasal Cannula
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Oklahoma
Lung Diseases, Obstructive, Bronchitis
Medication Adherence in COPD--A Self-Regulation Study
To test the effectiveness of a self-management program for chronic obstructive disease (COPD) patients. The program to improve adherence could be conducted by nurses or other clinic staff in settings where comprehensive…
- Conditions
- Lung Diseases, Obstructive, Bronchitis, Emphysema, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00005717
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Electronic Cigarette Use, Second Hand Smoke
Acute Health Effects of Passive Vape Among COPD Patients
The use of e-cigarettes is often permitted in otherwise smoke-free areas causing passive vape exposure for present individuals. Little is known about the potential adverse health effects of passive vape, and people with…
- Conditions
- Electronic Cigarette Use, Second Hand Smoke, Lung Function
- Trial name
- PASVAP (NCT04316234)
- Testing
- Passive vape
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Chronic Obstructive Pulmonary Disease
Comparing Treatment Efficacy With HD/MD Flu Plus Sal in Chronic Obstructive Pulmonary Disease (COPD) Patients
Chronic obstructive pulmonary disease is characterized as inflammatory airway with not fully reversible airflow limitation.Combination treatment with inhaled corticosteroid (ICS) and long-acting β2 agonists (LABA)attains an…
- Trial name
- NCT01131806
- Testing
- fluticasone/ salmeterol 125/25 mcg/puff, fluticasone/ salmeterol 250/25 mcg/puff
- Where
- Taiwan
- Volunteers
- 124 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Chronic Obstructive Pulmonary Disease
Phase 4 COPD and Suboptimal Inspiratory Flow Rate
Study is a randomized, double-blind, double-dummy, parallel-group study evaluating efficacy and safety of revefenacin vs. tiotropium in adults with severe to very severe COPD and suboptimal PIFR.
- Trial name
- PIFR-2 (NCT05165485)
- Testing
- Revefenacin, Tiotropium
- Where
- 76 sites in United States
- Volunteers
- 404 people
- Sponsor
- Theravance Biopharma
Chronic Obstructive Airway Disease, Neutrophil Function Disorder
Exercise and Neutrophil Function in COPD
Exercise is a cornerstone of pulmonary rehabilitation in the treatment of Chronic Obstructive Pulmonary Disease (COPD). Although researchers have shown numerous benefits with exercise in COPD patients, most studies have only…
- Trial name
- NCT02124343
- Testing
- Interval Exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hywel Dda Health Board
COPD, Asthma
Is Patients With Pulmonary Disease Benefit a Program With Yogic Exercises?
Is Yogic Exercises (12 weeks) increasing respiratory function, functional capacity and quality of life in patients with obstructive lung diseases. With follow up after 6 months.
- Trial name
- NCT02233114
- Testing
- Yogic exercises, Physiotherapy
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Sarcopenic Obesity, COPD
Prevalence of Sarcopenic Obesity in COPD
The goal of this observational study is to the purpose is to apply of ESPEN/EASO criteria for the diagnosis of sarcopenic obesity and calculation of OS prevalence in a sample of COPD patients.
- Trial name
- OS-BPCO (NCT06822504)
- Where
- Italy
- Volunteers
- 236 people
- Sponsor
- IRCCS San Raffaele Roma
Chronic Obstructive Pulmonary Disease
The Effect of STIOLTO™ RESPIMAT® on Fatigue in Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine whether exercise can be prolonged in COPD can by the inhaled bronchodilator Stiolto Respimat.
- Trial name
- NCT02845752
- Testing
- Stiolto Respimat
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Pulmonary Emphysema
Long Term Follow up Investigation of Endobronchial Valves in Emphysema
This is an observational prospective single arm multicentre study to observe the effect over 5 years of Zephyr endobronchial valve therapy for emphysema.
- Trial name
- LIVE (NCT01580215)
- Testing
- Zephyr Endobronchial Valve (EBV)
- Where
- Germany
- Volunteers
- 628 people
- Sponsor
- Pulmonx International Sàrl
COPD, Respiratory Insufficiency
Use of Autologous Stem/Stromal Cells In Chronic Lung Disorders: Obstructive (COPD) & Restrictive (RLD)
Pulmonary Disorders are often categorized as Obstructive or Restrictive disorders. This study will establish two channels of investigation, one group within each type of pulmonary dysfunction.
- Trial name
- cSVF-Lung (NCT03909750)
- Testing
- Lipoaspiration, AD-cSVF, Normal Saline IV
- Where
- 2 sites in United States, Honduras
- Volunteers
- 50 people
- Sponsor
- Healeon Medical Inc
Respiratory (Chronic Obstructive Pulmonary Disease)
Study for Assessing the Prevalence of Airflow Limitation in Outpatients With History of Smoking Attending Cardiology Clinics
Chronic Obstructive Pulmonary Disease (COPD) is a global health concern, associated with structural lung abnormalities causing persistent airflow limitation (AL) and often result from cigarette smoking.
- Trial name
- ALSAC (NCT07315958)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
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