Clinical trials: Pulmonary Disorder, Chronic Obstructive
Chronic Obstructive Pulmonary Disease, Multiple Comorbidity
Program of Integrated Care for Patients With Chronic Obstructive Pulmonary Disease and Multiple Comorbidities
Many patients with chronic obstructive pulmonary disease (COPD) also have other diseases referred to as comorbidities. Often these patients require health care by a variety of health care professionals from services linked to…
- Trial name
- PICCOPD+ (NCT01648621)
- Testing
- 40 minute standardized education session, Individualized action plan, Individualized care plan
- Where
- 2 sites in Canada
- Volunteers
- 470 people
- Sponsor
- Michael Garron Hospital
COPD, Nurse's Role
Does Longitudinal Nursing Follow-up Improve Smoking Cessation in Patients Referred for COPD Screening
a monocentric study to evaluate the efficacy of a longitudinal nursing follow up in smoking cessation in patients screened for Chronic obstructive pulmonary disease (COPD).
- Trial name
- BPCO (NCT05577767)
- Where
- France
- Volunteers
- 233 people
- Sponsor
- Centre Hospitalier de Valence
COPD, Interstitial Lung Disease
MOBoxy: MoblO2 to Maintain Oxygenation
Many patients with chronic lung disease (e.g., chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)) require supplemental oxygen (O2) at some point during their disease course.
- Trial name
- MOBoxy (NCT07222592)
- Testing
- MoblO2 control
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Jewish Health
Quality of Life, Exercise
The Effect of N-Acetylcystein on Quality of Life and Air Trapping During Rest and After Exercise
Treatment of COPD patients depends on the stage of the disease. First of all it is strongly recommended quit smoking, then bronchodilators drugs are added.
- Trial name
- NAC (NCT00476736)
- Testing
- Effect on small airways (N-Acetylcystein)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Pulmonary Disease, Chronic Obstructive
Effect of Expiratory Positive Pressure on Dynamic Hyperinflation and Ability to Exercise With Upper Limbs in COPD
The study will evaluate the effect of positive airway expiratory pressure (EPAP) on patients with chronic obstructive pulmonary disease (COPD) during submaximal upper limb exercise.
- Trial name
- NCT03073564
- Testing
- Endurance test for upper limbs, Functional test
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pulmonary Disease, Chronic Obstructive
Study of GSK961081 in Healthy Volunteer Subjects
GSK961081 is a new long-acting bronchodilator being developed for the treatment of chronic obstructive pulmonary disease (COPD). This study is the first clinical study in humans.
- Trial name
- NCT00887406
- Testing
- GSK961081 15mcg SD, GSK961081 3mcg SD, GSK961081 50mcg SD
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Rhinosinusitis
Laser Assisted Treatment of Chronic Sinusitis With and Without Light Activated Agents
Chronic rhinosinusitis (CRS) is common disorder which affects up to 13% of the US population. CRS affects numerous Quality of Life (QOL) factors including smell, sleep and communication.
- Trial name
- NCT00948519
- Testing
- Laser + ICG, Laser only
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York Head & Neck Institute
Chronic Graft Versus Host Disease
Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD)
Graft versus Host Disease (GVHD) is frequent after allogeneic stem cell transplantation (alloSCT). GVHD occurs following 2 patterns : acute GVHD (aGVHD) or chronic GVHD (cGVHD).
- Trial name
- TIL-GVHD (NCT06247150)
- Testing
- Additional blood sample, cGVHD target tissue biopsy
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Bordeaux
Asthma
A Clinical Trial to Study the Effects of Revamilast in Patients With Chronic Persistent Asthma
Asthma is a common, chronic inflammatory disease of the bronchial airways, with a reported prevalence in most industrialized countries of between 5 to 10 % of the adult population.
- Trial name
- NCT01436890
- Testing
- Revamilast
- Where
- 42 sites in Czechia, India and 3 more
- Volunteers
- 273 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Chronic Obstructive Pulmonary Disease
Adherence to Medication and Its Impact on Chronic Obstructive Pulmonary Disease (COPD) Exacerbations: The AMICE Prospective Study
Chronic Obstructive Pulmonary Disease (COPD) represents one of the most challenging chronic diseases of the 21st century: it is expected to be the fourth leading cause of death by 2030.
- Trial name
- AMICE (NCT01293890)
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
COPD (Chronic Obstructive Pulmonary Disease), Pulmonary Rehabilitation
EFFECTIVENESS OF COMBINED CONCENTRIC AND ECCENTRIC AEROBIC EXERCISE ON A TREADMILL IN PATIENTS WITH COPD: A RANDOMIZED CLINICAL TRIAL.
The aim of this study is to demonstrate the effectiveness of combined concentric and eccentric aerobic training in subjects with COPD, in terms of strength, lung capacity, functionality, and short-term health quality.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Pulmonary Rehabilitation, Eccentric Exercise Training
- Trial name
- NCT07627035
- Testing
- Eccentric and concentric aerobic exercice versus only concentric aerobic exercice
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Europea de Madrid
Chronic Obstructive Pulmonary Disease (COPD)
Identifying REsponders and Exploring Mechanisms of ACTION of the Endobronchial Coil Treatment for Emphysema
Rationale: The PneumRx RePneu Lung Volume Reduction Coil (RePneu LVR-coil) is a bronchoscopic lung volume reduction treatment designed to compress the areas of lung parenchyma most damaged by emphysema.
- Trial name
- REACTION (NCT02179125)
- Testing
- RePneu Lung Volume Reduction Coil System
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 48 people
- Sponsor
- University Medical Center Groningen
Chronic Obstructive Pulmonary Disease
A Study to Assess the Long-term Safety of QVA149
The study is designed to provide long-term safety data for QVA149 in patients with moderate to severe chronic obstructive pulmonary disease (COPD).
- Trial name
- ENLIGHTEN (NCT01120717)
- Testing
- QVA149
- Where
- 53 sites in Canada, France and 8 more
- Volunteers
- 339 people
- Sponsor
- Novartis Pharmaceuticals
Complex Regional Pain Syndromes, CRPS
Effect of Delta-9-Tetrahydrocannabinol on the Prevention of Chronic Pain in Patients With Acute CRPS (ETIC-Study)
The purpose of this study is to determine whether application of low dose Delta9-Tetrahydrocannabinol can prevent the development of chronic pain in patients with acute CRPS.
- Trial name
- NCT00377468
- Testing
- Delta9-Tetrahydrocannabinol
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Chronic Obstructive Pulmonary Disease, COPD Exacerbation
Testing a Prediction Algorithm Into a Running Telehealth System for Patients With COPD
This trial will test a COPD prediction algorithm into a telehealth system from the previous Danish large-scale trial, TeleCare North (NCT01984840).
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD Exacerbation, COPD Exacerbation Acute, COPD
- Trial name
- NCT05218525
- Testing
- Algorithm
- Where
- Denmark
- Volunteers
- 138 people
- Sponsor
- Aalborg University
Chronic Obstructive Pulmonary Disease, Asthma
Impact of Air Pollution on Chronic Respiratory Diseases
The aim of this study is to evaluate the impact of air pollution on the occurrence and clinical course of chronic respiratory diseases, and discover new biomarkers from various devices such as CT images that can indicate the…
- Conditions
- Chronic Obstructive Pulmonary Disease, Asthma, Idiopathic Pulmonary Fibrosis
- Trial name
- NCT03813810
- Testing
- Non
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Lumbar Radiculopathy
Effects of Decompression in Patient With Acute vs Chronic Lumbar Radiculopathy
The study will be done to evaluate the effectiveness of Lumbar Spinal Decompression in patients with acute vs chronic lumbar radiculopathy. Study design will be Randomized control trial and sample size will be 30.
- Trial name
- NCT04674917
- Testing
- Decompression + Hot pack, TENS, Mobilization, Exercise Therapy, Decompression + Hot pack , TENS , Mobilization , Exercise Therapy, Hot pack , TENS, Mobilization, Exercise therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Bronchitis, Bronchitis, Chronic
A Study of the Safety and Effectiveness of Levofloxacin Compared With Cefaclor in the Treatment of Adults With Chronic Bronchitis Experiencing Rapid Onset of Worsening of Symptoms Caused by Bacteria
The purpose of this study is to evaluate the safety and effectiveness of levofloxacin, an antibiotic, compared with cefaclor, another antibiotic, in the treatment of adults with chronic bronchitis experiencing rapid onset of…
- Trial name
- NCT00257140
- Testing
- levofloxacin
- Volunteers
- 367 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pulmonary Disease, Chronic Obstructive
Postmarketing Surveillance Study of Atrovent® in Chronic Obstructive Airways Disease
Study to obtain further information on the tolerability and efficacy of Atrovent® unit dose vial 500 µg in the treatment of Chronic Obstructive Airways Disease under conditions of daily practice
- Trial name
- NCT02236715
- Testing
- Atrovent®
- Volunteers
- 1,039 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease, Hypoxia
Effect of Oxygen Supplementation During Exercise in Chronic Obstructive Pulmonary Disease Patients
The project will test the hypothesis that lung ventilation during exercise is unaffected by oxygen supplementation. In addition, the acute effect of oxygen supplementation on dyspnoea, heart rate and blood pressure will be…
- Trial name
- NCT02108925
- Testing
- Oxygen
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- LHL Helse