Clinical trials: Pulmonary Embolism
Cancer, Solid Tumor
Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms
This study aims to assess biomarkers and their related polymorphisms in the context of cancer-associated thromboembolism, with a particular focus on their interaction with the immune system.
- Conditions
- Cancer, Solid Tumor, Thromboembolism, Cardiovascular Diseases
- Trial name
- CAT_PB (NCT06065592)
- Testing
- Palbociclib, Rivaroxaban, SNP
- Where
- 2 sites in Lebanon
- Volunteers
- 500 people
- Sponsor
- Lebanese University
Cancer, Thrombosis
Anticoagulation Length in Cancer Associated Thrombosis
This is a two year, multicentre, mixed methods feasibility study including a randomised controlled two-arm interventional trial, a nested qualitative study, focus groups and a United Kingdom (UK) wide survey exercise.
- Conditions
- Cancer, Thrombosis, Venous Thromboembolism, Deep Vein Thrombosis
- Trial name
- ALICAT (NCT01817257)
- Testing
- Low Molecular Weight Heparin (LMWH)
- Where
- 5 sites in United Kingdom
- Volunteers
- 2 people
- Sponsor
- Cardiff University
Pulmonary Embolism
Pulmonary MR Angiography and Lower Extremity MR Venous Imaging Using Gadofosveset (Ablavar)
The use of the contrast agent, Ablavar, will help with the diagnosis of pulmonary embolism in magnetic resonance imaging (MRI).
- Trial name
- NCT01165892
- Testing
- Gadofosveset Triodium
- Volunteers
- 15 people
- Sponsor
- Washington University School of Medicine
Pulmonary Embolism, Venous Thromboembolism
Prognostic Value of 2026 AHA/ACC Clinical Categorization in Acute Pulmonary Embolism Patients Presenting to the Emergency Department
Background: The 2026 American Heart Association/American College of Cardiology (AHA/ACC) Pulmonary Embolism Guideline (Creager et al., Circulation 2026) introduced a novel five-category (A-E) clinical classification system with…
- Conditions
- Pulmonary Embolism, Venous Thromboembolism, Acute Pulmonary Embolism
- Trial name
- APEX-2026 (NCT07805616)
- Testing
- 2026 AHA/ACC Clinical Risk Categorization
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Non-severe Pulmonary Embolism
Evaluation of the Effectiveness of Intensive Medical Follow-up with an Advanced Practice Nurse Compared with Medical Follow-up Alone in Non-severe Pulmonary Embolism.
In France, venous thromboembolism (VTE), which includes pulmonary embolism (PE) and deep-vein thrombosis (DVT), is the 3rd leading cause of cardiovascular disease, leading to major public health problems.
- Trial name
- InCaPE (NCT06598930)
- Testing
- Routine follow-up, Intensive follow-up
- Where
- France
- Volunteers
- 360 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Venous Thromboembolism
Predicting Bleeding Risk on Anticoagulant Therapy for Venous Thromboembolism
The main objective of the study is to develop or validate a clinical prediction rule for major bleeding in patients on oral anticoagulant therapy who have been safely anticoagulated without bleeding or venous thromboembolism…
- Trial name
- NCT00788736
- Where
- 12 sites in United States, Canada and 1 more
- Volunteers
- 2,537 people
- Sponsor
- Ottawa Hospital Research Institute
Venous Thromboembolism, Venous Thrombosis
Mexican Multidisciplinary Registry of Patients With Venous Thromboembolic Disease
REMMITE, a retrospective and prospective registry with one-year follow-up, will provide valuable insights into the clinical diagnosis, management, treatment trends as well as related outcomes of three cohorts: DVT, DVT-PE, PE…
- Conditions
- Venous Thromboembolism, Venous Thrombosis, Pulmonary Embolism
- Trial name
- REMMITE (NCT02877251)
- Volunteers
- 500 people
- Sponsor
- Registro Mexicano Multidisciplinario De Pacientes Con Enfermedad Tromboembolica Venosa
Venous Thromboembolic Disease, Pulmonary Embolism and Thrombosis
Alerting Providers at Patient Hospital Discharge to Consider Prescribing Rivaroxaban to Reduce Venous Thromboembolism
A new algorithm derived from only patient age and components of the complete blood count and basic metabolic panel can identify patients discharged from the hospital who may benefit from a blood thinner (called rivaroxaban) to…
- Conditions
- Venous Thromboembolic Disease, Pulmonary Embolism and Thrombosis, Deep Vein Thrombosis, Hospitalism
- Trial name
- eVTE (NCT06232551)
- Testing
- EHR (electronic health record) alert, No EHR (electronic health record) alert
- Where
- United States
- Volunteers
- 152,000 people
- Sponsor
- Scott C. Woller, MD
Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension
Validation of SEARCH, a Novel Hierarchical Algorithm to Define Long-term Outcomes After Pulmonary Embolism
Potential outcomes after PE occur on a spectrum: complete recovery, exercise intolerance from deconditioning/anxiety, dyspnea from concomitant cardiopulmonary conditions, dyspnea from residual pulmonary vascular occlusion…
- Trial name
- ValidSEARCH (NCT05568927)
- Testing
- SEARCH algorithm
- Where
- 8 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Diego
Deep Vein Thrombosis, Pulmonary Embolism
Registry of Hospitalized Patients Treated With Fondaparinux
Registry of Hospitalized patients at Brigham and Women's Hospital treated with Fondaparinux
- Trial name
- NCT00549705
- Volunteers
- 220 people
- Sponsor
- Brigham and Women's Hospital
Thrombosis, Deep Venous Thrombosis
Venous Thromboembolism and Haemostatic Disturbances in Patients With Upper Gastrointestinal Cancer
Cancer is a well known risk factor for venous thromboembolism (VTE) such as deep venous thrombosis (DVT) and pulmonary embolism (PE).
- Conditions
- Thrombosis, Deep Venous Thrombosis, Pulmonary Embolism, Venous Thromboembolism
- Trial name
- GIVTE (NCT00660205)
- Where
- Denmark
- Volunteers
- 285 people
- Sponsor
- University of Aarhus
Acute Pulmonary Embolism (PE)
Prognostic Factors for Acute Pulmonary Embolism in Critically Ill Patients
Acute pulmonary embolism (PE) is an important cause of in-hospital mortality and may be rapidly fatal if not diagnosed and treated.
- Trial name
- NCT01839266
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Pulmonary Embolism
Implementation of a Structured Post-pulmonary Embolism Follow-up Model
Venous thromboembolism (VTE), clinically presenting as deep vein thrombosis or pulmonary embolism (PE) is the third most frequent cardiovascular disease and is associated with substantial short- and long-term morbidity and…
- Trial name
- NCT06037096
- Testing
- Attend-PE model
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Aalborg University Hospital
Pulmonary Embolism, Atrial Fibrillation
Evaluation of the Accuracy and Precision of the INRatio® Prothrombin Time (PT) Monitoring System With New INRatio Test Strip Designed for Low Sample Volume and Heparin Insensitivity
This is a multi-center study designed to evaluate the accuracy and precision of the INRatio® Prothrombin Time (PT) Monitoring System, utilizing the INRatio test strip newly designed for low sample volume and heparin…
- Conditions
- Pulmonary Embolism, Atrial Fibrillation, Deep Vein Thrombosis
- Trial name
- ECLIPSE-01 (NCT01037270)
- Where
- 4 sites in United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Abbott RDx Cardiometabolic
Venous Thromboembolism, Pediatrics
Using a Real-Time Risk Prediction Model to Predict Pediatric Venous Thromboembolism (VTE) Events
The study will evaluate the effectiveness of a novel, real-time risk prediction model for identifying pediatric patients at risk for developing in-hospital blood clots (or venous thromboembolism [VTE]) based on data easily…
- Conditions
- Venous Thromboembolism, Pediatrics, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT04574895
- Testing
- Hematology Review
- Where
- United States
- Volunteers
- 17,427 people
- Sponsor
- Vanderbilt University Medical Center
Shortness of Breath, Acute Respiratory Failure
Enhanced FoCUS in Patients With Shortness of Breath
Retrospective observational study performed in a internal medicine ward of a French university hospital. Included patients were hospitalized for acute shortness of breath who have benefited from a eFOCUS which was defined as a…
- Trial name
- eFOCUS (NCT05403619)
- Testing
- Diagnostic test
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Nantes University Hospital
Pulmonary Embolism With Right Ventricle Enlargement
Diuretic Versus Placebo in Pulmonary Embolism
Pulmonary Embolism (PE) is a frequent and severe disease with an annual incidence of about 75000 cases in France and a short-term mortality rate of about 10%.
- Trial name
- DiPER (NCT02268903)
- Testing
- Diuretics : Furosemide
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease, Aortic Aneurysm
Computed Tomography Dose Reduction Using Sequential or Fast Pitch Sprial Technique
This is a prospective, controlled observational trial of patients undergoing clinically indicated cardiothoracic computed tomography (CT), including pulmonary or aortic angiography and coronary CT angiography (CCTA).
- Conditions
- Coronary Artery Disease, Aortic Aneurysm, Pulmonary Embolism
- Trial name
- CTDOSE (NCT01272453)
- Where
- 9 sites in United States, Saudi Arabia
- Volunteers
- 2,640 people
- Sponsor
- Gilbert L. Raff, MD
Venous Thromboembolism (VTE), Exercise Therapy
Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism
Up to half of patients with pulmonary embolism (PE) suffer from impaired quality of life, reduced physical capacity, and symptoms like shortness of breath even three months after diagnosis, despite standard treatment with…
- Conditions
- Venous Thromboembolism (VTE), Exercise Therapy, Quality of Life (QOL), Anxiety Depression
- Trial name
- RehabPE (NCT07143539)
- Testing
- Exercise-based rehabilitation program
- Where
- 6 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Deep Vein Thrombosis
Single Comprehensive Ultrasound to Rule Out DVT in High-risk Patients
To determine the rate of thromboembolic complications (including death attributed to thromboembolic disease) in patients with a score rated as "DVT likely" on a formalized scoring system, when anticoagulation therapy is withheld…
- Trial name
- NCT00333697
- Testing
- Comprehensive Duplex Ultrasound (diagnostic study)
- Where
- 2 sites in United States
- Volunteers
- 199 people
- Sponsor
- Intermountain Health Care, Inc.