Clinical trials: Pulmonary Function Impairment
Atrial Fibrillation, Heart Failure, Systolic
Atrial FIbrillation Treatment With Cryoballoon in Heart failurE (AFICHE)
In this study 404 patients with heart failure and an ejection fraction of 0.40 or less, with paroxysmal atrial fibrillation, will be randomly assigned to standard treatment or standard treatment plus a session of cryoballoon…
- Trial name
- AFICHE (NCT03573869)
- Testing
- Cryoballoon ablation
- Where
- Greece
- Volunteers
- 404 people
- Sponsor
- G.Gennimatas General Hospital
COPD, Cognitive Impairment
Working Memory Training in COPD Patients: the Cogtrain-Trial
General cognitive impairment is highly prevalent in chronic obstructive pulmonary disease (COPD) patients. Domain-specific cognitive impairments include deficits in domains such as cognitive flexibility, verbal memory, working…
- Trial name
- NCT03073954
- Testing
- Working memory training, Standardised healthy lifestyle coaching
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Maastricht University Medical Center
COPD, Upper Extremity
Cognitive Impairment and Upper Extremity Performance in COPD
Within the scope of this study, COPD patients will be divided into two groups according to cognitive dysfunction. Pulmonary function test, COPD assessment scale, Mini-Mental State Examination and Montreal Cognitive Assessment…
- Conditions
- COPD, Upper Extremity, Upper Limb Function, Cognitive Impairment
- Trial name
- COPD (NCT05137483)
- Testing
- Functional tests
- Volunteers
- 80 people
- Sponsor
- Izmir Katip Celebi University
Respiration Disorders
Elastic-Band Resistance and Breathing Training for Older Adults With Pulmonary Function Impairment
The goal of this clinical trial is to learn whether elastic-band resistance training, with or without breathing training, can improve lung function and physical function in older adults with pulmonary function impairment living…
- Trial name
- EBBT-PFI (NCT07612072)
- Testing
- Elastic-Band Resistance Training Plus Breathing Training, Elastic-Band Resistance Training
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Sport University
Cystic Fibrosis
Assessment of Cognitive Function and Exercise Capacity in Cystic Fibrosis
No studies in the literature have investigated the simultaneous effects of cognitive function, exercise capacity and arterial stiffness in adult patients with CF.
- Trial name
- NCT06175182
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Respiratory Impairment, Elevated Blood Pressure
Walking and Blood Pressure in Older Adults With Respiratory Impairment.
The purpose of this study is to evaluate the effect of an 8-week walking program on blood pressure in inactive older adults with respiratory impairment, a condition where lung function is sub-optimal for a person's age.
- Conditions
- Respiratory Impairment, Elevated Blood Pressure, Physical Inactivity
- Trial name
- NCT06033417
- Testing
- Increased lifestyle walking (intervention), Health education only (control)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Iowa State University
COPD, COPD (Chronic Obstructive Pulmonary Disease)
The Efficacy of Non-invasive Brain Stimulation (NIBS) on Cognitive Functions in Patients With Chronic Obstructive Pulmonary Disease (COPD)
The goal of this clinical trial is to examine if non-invasive brain stimulation (NIBS) can enhance cognitive function with chronic obstructive pulmonary disease (COPD) population.
- Conditions
- COPD, COPD (Chronic Obstructive Pulmonary Disease), Cognitive Impairment (CI), Non-invasive Brain Stimulation
- Trial name
- NIBS COPD (NCT07332169)
- Testing
- Non-invasive brain stimulation
- Where
- Saudi Arabia
- Volunteers
- 22 people
- Sponsor
- Ministry of Health, Kuwait
COPD
Impairments That Affect Correct Inhaler Use in COPD
INHALE is a one-year, multi-site observational research study funded by Viatris, with two aims: 1. Determine the prevalence of both cognitive impairment and impaired manual dexterity in stable out-patients with chronic…
- Trial name
- INHALE (NCT06135324)
- Where
- 9 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- COPD Foundation
Multiple Sclerosis
Lung Volume Recruitment for Lung Function and Cough Impairment in Multiple Sclerosis
Multiple sclerosis is a neurological disease that can affect lung function and cough efficacy. This pilot study will examine whether the lung volume recruitment technique can slow down the decline in lung function and cough.
- Trial name
- NCT01891071
- Testing
- Lung volume recruitment
- Where
- 2 sites in Canada
- Volunteers
- 35 people
- Sponsor
- Ottawa Hospital Research Institute
Chronic Obstructive Pulmonary Disease (COPD)
Sensorimotor Function in COPD
The aim of this study was to investigate the level of sensorimotor function impairment according to disease stage in individuals with Chronic Obstructive Pulmonary Disease (COPD) and to determine whether functional differences…
- Trial name
- NCT07825636
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Pneumonia
A Study To Investigate The Pharmacokinetics, Safety And Tolerability Of An Intravenous And Oral Form Of A Compound In Subjects With Varying Degrees Of Renal Impairment And Normal Renal Function
This study will evaluate what effect renal dysfunction has on a drug that has an intravenous (CP-70,429) and an oral form (PF-03709270).
- Trial name
- NCT00759564
- Testing
- CP-70,429 and PF-03709270
- Where
- 2 sites in United States, Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Pfizer
Post COVID-19 Condition, Cognitive Impairment
Cognitive Impairment and Fatigue After Mild to Moderate COVID-19
The primary aim of the project is to map fatigue, cognitive and visual dysfunctions and possible underlying pathophysiological mechanisms in persons with long-term symptoms after a mild to moderate COVID-19 infection.
- Conditions
- Post COVID-19 Condition, Cognitive Impairment, Fatigue, Mental
- Trial name
- NCT06042530
- Testing
- Neuropsychological investigation, Optometric investigation, Magnetic Resonance Imaging
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Danderyd Hospital
Amyotrophic Lateral Sclerosis (ALS)
Developing New Ways to Detect Respiratory Impairment Early in ALS
The goal of this observational study is to develop new ways to detect early changes associated with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.
- Trial name
- NCT07844590
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Chronic Obstructive Pulmonary Disease, Balance
Investigation of Impairments in Body Functions and Structures, Activities and Participation Restrictions in COPD
This cross-sectional study aims to investigate to the impairments in body functions and structures, activities and participation restrictions according to the International Classification of Functioning, Disability and Health…
- Conditions
- Chronic Obstructive Pulmonary Disease, Balance, Activity, Motor, Participation, Patient
- Trial name
- NCT05632120
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
COPD
Effects of Combined Cognitive Rehabilitation in COPD Patients
This study was to examine the effect of endurance training combined with cognitive training in patients with COPD. The intervention group underwent Cognitive Training added to Endurance Training and the control group underwent…
- Trial name
- NCT03907839
- Testing
- clinical trials
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculty of Medicine, Sousse
Postoperative Pulmonary Function Impairment
Supervised vs Non-Supervised Incentive Spirometry After CABG
This study aims to evaluate the effect of supervised incentive spirometry (SIS) compared to unsupervised incentive spirometry (Non-SIS) on pulmonary function in patients following coronary artery bypass graft (CABG) surgery.
- Trial name
- SIS-CABG (NCT07343921)
- Testing
- Supervised Incentive Spirometry (SIS), Non-Supervised Incentive Spirometry (Non-SIS)
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Padjadjaran
NSCLC (advanced Non-small Cell Lung Cancer)
Pharmacokinetic Study of HS-10365 Capsule in Subjects with Hepatic Impairment and Normal Hepatic Function
This study will be conducted in subjects with moderate Hepatic Impairment, mild hepatic Impairment and normal hepatic function. The study will be conducted in two stages.
- Trial name
- NCT06823258
- Testing
- HS-10365
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Acute Respiratory Distress Syndrome, Neuromyopathies
Effect of Randomization to Neuromuscular Blockade on Physical Functional Impairment and Recovery in ARDS
The proposed work will determine the effect of neuromuscular blockade on physical function and recovery in patients with ARDS. The investigators will conduct a prospective ancillary study at five PETAL clinical centers that will…
- Trial name
- PRIMROSE (NCT03038906)
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- University of Washington
Critical Illness, Ventilator Lung
Early and Intensive Occupational Therapy in Mechanical Ventilated Patients
This study evaluates the efficacy of an early and intensive occupational therapy (OT) protocol in critical adult patients requiring mechanical ventilation. Evaluating the functional independence at hospital discharge.
- Conditions
- Critical Illness, Ventilator Lung, Impairment, Cognitive, Impairment, Coordination
- Trial name
- NCT04819529
- Testing
- Early and Intensive Occupational Therapy
- Where
- Chile
- Volunteers
- 226 people
- Sponsor
- University of Chile
Breast Cancer, Sarcoma
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
This is a phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining the impact of riluzole therapy on circulating brain derived neuropathic factor (BDNF) levels in cancer survivors (recently…
- Conditions
- Breast Cancer, Sarcoma, Gastric Cancer, Lung Cancer
- Trial name
- NCT06580002
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Irvine