Clinical trials: Pulmonary Lobectomy
Postoperative Chronic Cough
Effect of Disconnecting Pulmonary Vagus Nerve Branch on Chronic Cough After Unilateral Thoracoscopic Lobectomy
The purpose of this study was to determine whether disconnecting pulmonary vagus nerve branch can abatement chronic cough in patients undergoing unilateral thoracoscopic lobectomy,compared with preserving pulmonary vagus nerve…
- Trial name
- NCT04247997
- Testing
- disconnect pulmonary vague nerve branches
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Han Yuan
Lung Neoplasms
Effects of Early Mobilization and Feeding After Lobectomy
This randomized controlled study evaluates the effects of early mobilization and early oral feeding, two components of the Enhanced Recovery After Surgery (ERAS) protocol, on postoperative outcomes in adult patients with lung…
- Trial name
- NCT07749950
- Testing
- Early Mobilization, Early Oral Feeding, Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ege University
Lung Disease
ENDO GIA Stapler With Duet Tissue Reinforcement System (TRS) Used in Pulmonary Resections
The objective of this study is to confirm superiority between a test treatment group using Endo GIA stapler with Duet Tissue Reinforcement System (TRS) and a current international standard of care group using a conventional…
- Trial name
- NCT01241617
- Testing
- Duet TRS, Endo GIA
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG
Lung Cancer
Spectrum Analysis in Ex-vivo Human Lungs
This study will analyze spectral features of the radiofrequency of lung tumors in ex-vivo human lungs. The resected specimens will be evaluated using the spectrum analysis to determine the localization rate of the targets.
- Trial name
- NCT03356743
- Testing
- Spectrum Analysis
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Lung Cancer
Coaxial Drainage Versus Standard Chest Tube After Pulmonary Lobectomy
Objectives: Chest tubes are routinely inserted after thoracic surgery procedures in different size and numbers. The aim of this study is to assess the efficacy of Smart Drain Coaxial drainage compared with two standard chest…
- Trial name
- NCT04877925
- Testing
- standard chest tubes, coaxial chest tube
- Where
- Italy
- Volunteers
- 98 people
- Sponsor
- Marco Anile
Non-small Cell Lung Cancer
Suction on Post-Operative Chest Tubes
The level of suction on post-operative chest tubes after video-assisted thoracoscopic surgery (VATS) lobectomy for lung cancer has previously shown to affect duration of drainage.
- Trial name
- SPOCT (NCT02911259)
- Testing
- Suction is set to -2 cmH2O, Suction is set to -10 cmH2O
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Non-small Cell Lung Cancer, Thoracic Surgery
Robotic Lobectomy vs. Thoracoscopic Lobectomy for Early Stage Lung Cancer: RCT
During video-assisted thoracoscopic lobectomy (VATS), the surgeon inserts a small camera attached to a thoracoscope that puts the image onto a video screen.
- Trial name
- NCT02617186
- Testing
- Video-assisted thoracoscopic surgery, Robotic thoracic surgery
- Where
- Canada
- Volunteers
- 446 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Non Small Cell Lung Cancer
Multiple-portal VATS Versus Uniportal VATS Lobectomy for Non-small Cell Lung Cancer
This study evaluate multiple-portal VATS and uniportal VATS lobectomy for NSCLC, half of participants will receive multiple VATS, while the other half will receive uniportal VATS lobectomy.
- Trial name
- MVUVLC (NCT02462356)
- Testing
- Uniportal VATS, Conventional VATS
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Complications During Rehabilitation Stay
Effect of Pursed-lips Breathing Combined With Aerobic Walking Exercise on Oxygenation and Activity Endurance in Lung Cancer Patients After Lobectomy
The effects of pursed-lip breathing or aerobic walking exercise in increasing muscle strength and motility and relieving dyspnea have been proved.
- Trial name
- NCT06118164
- Testing
- pursing- lip breathing combined with aerobic walking exercise, pursing- lip breathing, aerobic walking exercise
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taichung Tzu Chi Hospital
Non-small Cell Lung Cancer Stage I, Lung Adenocarcinoma
Comparison of cVATS Segmentectomy Versus Lobectomy for Lung Adenocarcinoma in Situ and With Microinvasion
This is a Prospective, open-label, parallel, multi-center, Phase III randomized trial to evaluate the efficacy and safety of video-assisted thoracoscopic segmentectomy versus Lobectomy in treating patients with Lung…
- Trial name
- cVATS (NCT02011997)
- Testing
- patients undergo cVATS segmentectomy, Patients undergo cVATS lobectomy
- Where
- 6 sites in China
- Volunteers
- 500 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Lung Cancer
Use of Harmonic Scalpel to Decrease Lymphatic and Chest Tube Drainage After Lymph Node Dissection With Lobectomy.
In an effort to elucidate whether the Harmonic Scalpel will improve sealing lymphatics and decrease lymphatic drainage thereby decreasing the length of time that chest tubes are required and minimizing length of stay; the…
- Trial name
- NCT00591552
- Testing
- Harmonic ACE23P Scalpel, Electrocautery
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sentara Cardiovascular Research Institute
Lung Cancer
Videothoracoscopic (VATS) vs. Robotic Approach for Lobectomy or Anatomical Segmentectomy
This is a prospective, randomized, multicenter study on 300 patients (150 VATS lobectomies and 150 robotic lobectomies) affected by early stage (I-II) lung cancer. The expected recruitment is one year and two year follow up.
- Trial name
- ROMAN (NCT02804893)
- Testing
- VATS, RATS
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Istituto Clinico Humanitas
Lung Cancer (NSCLC)
Cardiorespiratory Fitness After Lobectomy Versus Sublobar Resection
This observational study will compare changes in cardiorespiratory fitness after lobectomy and sublobar resection. Sublobar resection includes segmentectomy and wedge resection.
- Trial name
- NCT07841249
- Testing
- Lobectomy, Sublobar Resection
- Where
- China
- Volunteers
- 604 people
- Sponsor
- Tongji Hospital
Lung Cancer, Neoadjuvant Therapy
Sleeve Lobectomy Following Neoadjuvant Therapy in NSCLC
The goal of this observational, retrospective, multicenter cohort study is to evaluate the surgical and oncologic outcomes of sleeve lobectomy performed via minimally invasive (RATS/VATS) or open thoracotomy approaches in…
- Trial name
- NCT07135856
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Chest Hospital
Lung Cancer, Vagus Nerve Injuries
Vagus Nerve Preservation and Chronic Cough in Non-small Cell Lung Cancer Surgery
Lung cancer is the leading cause of cancer death worldwide. Surgical resection is the main treatment for resectable non-small-cell lung cancer (NSCLC), and lobectomy with systemic mediastinal lymph node dissection is the standard…
- Conditions
- Lung Cancer, Vagus Nerve Injuries, Cough
- Trial name
- NCT04923412
- Testing
- Pulmonary branch of vagus nerve preserved, Pulmonary branch of vagus nerve not preserved
- Where
- South Korea
- Volunteers
- 214 people
- Sponsor
- Seoul National University Bundang Hospital
Lung Cancer, Pain, Postoperative
Pain Control After VATS Anatomical Pulmonary Resections
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced.
- Conditions
- Lung Cancer, Pain, Postoperative, Thoracic Neoplasms
- Trial name
- NCT05993273
- Testing
- Epidural, ESP block, Cryoanalgesia
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University Hospital Padova
NSCLC
Sub-lobectomy vs Lobectomy in IIA-IIIB NSCLC After Neoadjuvant IO+Chemo
This study is a prospective, randomized controlled multicenter clinical trial. The study population consisted of non-small cell lung cancer（NSCLC） patients in stage IIA-IIIB (IASLC 9th edition) who received immunotherapy combined…
- Trial name
- NCT07612722
- Testing
- Sub-lobectomy, Lobectomy
- Where
- China
- Volunteers
- 585 people
- Sponsor
- Wen-zhao ZHONG
Lung Neoplasm Malignant
Immune Response Following Lobectomy Along With or Without Bilateral Transcervical Mediastinal Lymphadenectomy
Any kind of anatomical lung resection for lung cancer with curative intent has to be accompanied by formal mediastinal lymph node dissection.
- Trial name
- NCT04778826
- Testing
- Lymphadenectomy
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Otto Wagner Hospital
Lung Cancer Patients
Inter Costal Catheters for Video-Assisted Thoroscopic (VATS) Lobectomy
A pilot study to observe satisfaction of analgesia with intercostal catheters after VATS lobectomy.
- Trial name
- NCT01213654
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Nonsmall Cell Lung Cancer
Effects of Acupuncture Stimulation on Systemic Inflammation
60 ASA physical status I or II patients, aged 18-75 years old , scheduled for elective video-assisted thoracoscopic lobectomy surgery,will be randomized into 2 groups,with 30 patients in each group: 1. control group and 2.
- Trial name
- NCT02951611
- Testing
- Acupuncture stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital