Clinical trials: Pulmonary Lobectomy
Frailty, Thoracic
Auricular Acupressure in Prehabilitation
Complementary medicine is recognized for its ability to enhance appetite, increase energy, reduce anxiety, decrease pain, and improve sleep, among many other benefits.
- Conditions
- Frailty, Thoracic, Prehabilitation, Lung Surgery
- Trial name
- NCT06516198
- Testing
- Auricular Acupressure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago
Lung Disease, Pulmonary Lobectomy
PleuraSeal Post Market Study (Europe)
To further characterize the PleuraSeal Sealant System as compared to standard of care (sutures and staples only) in subjects undergoing an elective pulmonary lobectomy and segmentectomy via open thoractomy.
- Trial name
- NCT00704171
- Testing
- Standard Tissue Closure Techniques, PleuraSeal Lung Sealant System
- Where
- 9 sites in United States, Austria and 4 more
- Volunteers
- 121 people
- Sponsor
- Integra LifeSciences Corporation
Solitary Mass, Lung Diseases
Comparison for Pethidine Requirement in Patients Received Spinal Morphine 0.2 and 0.3 mg for Post Lobectomy Analgesia
The purpose of the study is to evaluate the amount of total pethidine requirement during the 48 hour postoperative period after receiving spinal morphine 0.2 and 0.3 mg.
- Trial name
- pain (NCT01236495)
- Testing
- spinal morphine 0.3 mg, spinal morphine 0.2 mg
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Lung Cancer
ENDO GIA™ Stapler With ENDO GIA™ Reload With Tri-Staple™ Technology in a Pulmonary Resection
The objectives of this clinical trial are to compare the incidence and duration of air leaks and the incidence of prolonged air leaks (defined as > 5 days by the Society for Thoracic Surgery) when using the ENDO GIA™ Stapler with…
- Trial name
- NCT01241565
- Testing
- ENDO GIA™ Stapler with TRI-STAPLE™ Technology
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Medtronic - MITG
Lung Cancer, Complication of Surgical Procedure
Comparison of LigaSure to Conventional Electrocoagulation in Video-assisted Thoracoscopic Surgery Lobectomy
Surgical treatment of lung cancer consists of two elements: anatomical lung resection (segmentectomy, lobectomy or pneumonectomy) followed by mediastinal lymph node dissection (MLND).
- Trial name
- NCT03125798
- Testing
- LigaSure™, Monopolar electrocautery
- Where
- Poland
- Volunteers
- 216 people
- Sponsor
- Wielkopolskie Centrum Pulmonologii i Torakochirurgii
Smoking, Oxygen Deficiencies
The Effects of Secondary Smoking During One Lung Ventilation
Smoking and perhaps secondary smoking is associated with many perioperative and postoperative complications, especially respiratory events. Hypoxemia and airway damage can be associated with secondary smoking.
- Trial name
- NCT03006224
- Testing
- One Lung Ventilation
- Volunteers
- 60 people
- Sponsor
- Inonu University
Pulmonary Surgical Procedures
Post-lobectomy Use of Glucose for Pleurodesis and Air-leak Cessation. A Feasibility Trial.
It is common practice to leave a chest drainage catheter after lung surgical resections to manage air leaks. The air leakage will usually stop in the initial postoperative days, but in a few patients, it will last for a longer…
- Trial name
- PLUG (NCT02376218)
- Testing
- Hypertonic 50% dextrose pleurodesis
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lung Cancer
Video-Assisted Surgery in Treating Patients With Non-small Cell Lung Cancer
RATIONALE: Video-assisted surgery may be an effective treatment and have fewer side effects than conventional surgery in patients with non-small cell lung cancer.
- Trial name
- NCT00003692
- Testing
- therapeutic thoracoscopy, video-assisted surgery
- Where
- 115 sites in United States, Puerto Rico and 1 more
- Volunteers
- 128 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Non-small Cell Lung Cancer Stage I, Surgery
Segmentectomy vs Lobectomy
Actual indications for stage Ia NSCLC patients suggest lobectomy and lymphadenectomy. On the other hand, recent studies reported non-inferiority of segmentectomy in case of nodule < 2cm or with ground glass appearance at computed…
- Trial name
- NCT06180239
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lung Surgery
Evaluation of the Effectiveness and Security of TenaTac® in the Prevention of Air Leaks in Thoracic Surgery
Lung surgery remains a high-risk procedure, with serious adverse events that can occur later, including postoperative bleeding or hemothorax, pneumopathy or surgical site infection but also ... per- and post-operative air leaks.
- Trial name
- TENATAC (NCT06597604)
- Testing
- Intraoperative use of TenaTac in lung surgery, Intraoperative use of usual sealant in lung surgery
- Where
- 2 sites in France
- Volunteers
- 154 people
- Sponsor
- Hopitaux Prives de Metz, Groupe UNEOS
Malignant Neoplasm of Bronchus or Lung, Unspecified
Cost-consequence Analysis of Parenchymal Stapling Device Versus Hand-sewing for Pulmonary Lobectomy in Lung Disease
The purpose of this study is to compare the efficacy and cost difference of using a parenchymal stapling device versus hand sewing for a pulmonary lobectomy in patients with lung disease (mass or others).
- Trial name
- NCT01575314
- Testing
- stapling device
- Where
- Thailand
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Carcinoma, Non-Small-Cell Lung
Sublobar Resection Versus Lobectomy for cT1N0M0 Non-small-cell Lung Cancer
The incidence rate of ground-glass opacity (GGO) has been increasing these years. A great number of retrospective studies suggested that sublobar resection was better for some GGO patients.
- Trial name
- NCT03108560
- Testing
- sublobar resection, lobectomy
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai Zhongshan Hospital
Non-Small Cell Lung Cancer, Stage IA Non-Small Cell Lung Cancer
Segmentectomy Versus Lobectomy for Deep Solid-Dominant Early-Stage NSCLC
SOLID is a multicenter, open-label, randomized, controlled, phase III non-inferiority trial comparing anatomic segmentectomy with lobectomy in patients with deeply located, solid-dominant, clinical stage IA non-small cell lung…
- Trial name
- SOLID (NCT07698990)
- Testing
- Anatomic Segmentectomy, Anatomic Lobectomy
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Chest Hospital
Pulmonary Surgical Procedures, Thoracic Surgery, Video-assisted
Registry of the Spanish Society of Thoracic Surgery
ReSECT is a project promoted by the Spanish Society of Thoracic Surgery with the aim not only to become an indefinite, dynamic and inclusive registry, but also to establish a common structural framework for the development of…
- Conditions
- Pulmonary Surgical Procedures, Thoracic Surgery, Video-assisted, Robotic Surgical Procedures, Thoracotomy
- Trial name
- ReSECT (NCT05600569)
- Where
- Spain
- Volunteers
- 30,000 people
- Sponsor
- Sociedad Española de Cirugía Torácica
Non Small Cell Lung Cancer
Robot-Assisted vs. Video-Assisted Lobectomy for NSCLC (RAVAR)
Video-assisted thoracic surgery (VATS) has been recommended by clinical guidelines as one of the preferred surgeries for early-stage non-small cell lung cancer (NSCLC) for many years.
- Trial name
- RAVAR (NCT06524427)
- Testing
- Robot-assisted lobectomy, Video-assisted lobectomy
- Where
- 23 sites in China
- Volunteers
- 1,124 people
- Sponsor
- Sun Yat-sen University
Pain, Postoperative, Lung Neoplasm
PATHOS Study Pain Assessment in Thoracic Oncologic Surgery
A randomized prospective trial to assess whether the use of loco regional anesthesia as adjuvant analgesic therapy is more effective of intravenous analgesia only.
- Trial name
- PATHOS (NCT03134729)
- Testing
- Ropivacaine for Serratus Plane Block (SPB)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Thoracic Surgery Lung, Post-operative Thoracic Air Leak
A Phase II Prospective, Single Blinded, Randomized Trial of Hemopatch Compared to Standard Techniques to Achieve Air Leak Control After Complex Thoracic Surgical Procedures
The purpose of this study is to explore whether the addition of Hemopatch to standard care can reduce prolonged air leaks and shorten the use of air drainage tube after surgery in thoracic lung surgery patients at high risk for…
- Trial name
- Hemopatch (NCT02364791)
- Testing
- standard techniques used to achieve air leak control, Hemopatch
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- National Cancer Institute, Naples
Primary Lung Cancer, Benign Lung Disease
SP Thoracic IDE Study
To confirm the safety and performance of the da Vinci SP Surgical System, Instruments and Accessories in pulmonary lobectomy, and in thymectomy procedures.
- Conditions
- Primary Lung Cancer, Benign Lung Disease, Thymoma, Myasthenia Gravis
- Trial name
- NCT05150210
- Testing
- Robotic-Assisted Surgery
- Where
- 6 sites in United States
- Volunteers
- 32 people
- Sponsor
- Intuitive Surgical
Video-assisted Thoracoscopic Surgery, Inflammatory Reaction
Comparison of Inflammatory Cytokine Levels Between Single-port and Three-port Thoracoscopic Lobectomy in the Treatment of Non-small Cell Lung Cancersurgery on Perioperative Clinical Indexes、Inflammatory Reaction and Quality of Life Scores of Patients With Non-small Cell Lung Cancer
Many recent studies have shown that surgical trauma will result in an immunosuppressive state. Combined with the effect of surgical stress, it will often lead to metabolic changes, systemic inflammatory response, and other…
- Conditions
- Video-assisted Thoracoscopic Surgery, Inflammatory Reaction, Life Scores
- Trial name
- NCT05070026
- Testing
- uni-portal VATS group, three port VATS group
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Shengjing Hospital
Lung Cancer
Comparison of Efficacy of Paravertebral and Epidural Analgesia After Videothoracoscopic Lung Lobectomy
Thoracic surgery correlates with significant pain in postoperative period. In order to alleviate the pain various combinations of pharmaceuticals and administration methods are employed.
- Trial name
- NCT02040662
- Testing
- Continuous Thoracic Epidural Block, Continuous Thoracic Paravertebral Block, Patient-Controlled Analgesia with Morphine
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Pulmonary Hospital Zakopane