Clinical trials: Pulmonary Lobectomy
Non-Small Cell Lung Cancer, Postoperative Air Leak
Progel Platinum for Air Leak Reduction After VATS Lobectomy for NSCLC
This multicenter randomized trial evaluates whether routine use of Progel Platinum surgical sealant on stapled fissure lines during VATS upper or lower lobectomy for NSCLC reduces pleural drainage duration compared with standard…
- Conditions
- Non-Small Cell Lung Cancer, Postoperative Air Leak, NSCLC
- Trial name
- E-SEAL (NCT07479277)
- Testing
- Progel Platinum, Mechanical Stapling
- Where
- 6 sites in Italy
- Volunteers
- 160 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Lung Cancer
Lung Cancer STARS Trial - STARS Revised Clinical Trial Protocol: Stereotactic Ablative Radiotherapy (SABR) in Stage I Non-small Cell Lung Cancer Patients Who Can Undergo Lobectomy
The goal of this clinical research study is to evaluate the outcome of a standard radiation treatment called stereotactic radiotherapy (SRT) for NSCLC.
- Trial name
- NCT02357992
- Testing
- Stereotactic Body Radiotherapy (SABR)
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Cancer (Diagnosis), Lobectomy
Simplified Exercise-based Risk Assessment in Lung Cancer
Physiological evaluation is part of the preoperative risk estimation in patients with lung cancer, and it aids in the choice of treatment.
- Conditions
- Lung Cancer (Diagnosis), Lobectomy, Surgery Complications, Neoadjuvant Chemoimmunotherapy
- Trial name
- EXHALE-CO2 (NCT07506889)
- Where
- 5 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Linkoeping University
Thoracotomy, Toracosurgery
Preoperative Nutritional Status and Postoperative Outcomes in Geriatric Lung Resection
Malnutrition is a common comorbidity in patients undergoing thoracic surgery. Furthermore, chronic diseases, polypharmacy, low nutrient intake, reduced appetite, and psychological factors-all frequently observed in geriatric…
- Conditions
- Thoracotomy, Toracosurgery, Thoracic Anesthesia, Older Adults (65 Years and Older)
- Trial name
- NCT07889336
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection
Pre-incisional Infiltration With Ropivacaine Plus Triamcinolone for Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection, Segmentectomy, Lobectomy of the Lungs
- Trial name
- NCT07603921
- Testing
- Pre-incisional infiltration with ropivacaine plus triamcinolone, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 346 people
- Sponsor
- Beijing Tiantan Hospital
VATS Lobectomy, VATS Segmentectomy
Care Pathway for Patients Undergoing VATS Lobectomy or Segmentectomy
The goal of this study is to create a unified SOP for care of subjects undergoing VATS lobectomy and segmentectomy by members of the Division of Thoracic Surgery.
- Conditions
- VATS Lobectomy, VATS Segmentectomy, Care Pathway, Lung Nodule
- Trial name
- NCT03024294
- Testing
- Post-operative care pathway for patients undergoing VATS lobectomy or segmentectomy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Lobectomy
Tegileridine Combined With Intercostal Nerve Block After Thoracoscopic Lung Resection
Combining tegileridine PCIA with ICNB targeting peripheral nerves, may constitute an ideal analgesic model with complementary advantages.
- Trial name
- NCT07386626
- Testing
- Tegileridine, Intercostal Nerve Block, Sufentanil
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Tongji Hospital
Hyperglycemia Stress
TIVA and VIMA on Blood Glucose and Insulin Levels in Lung Lobectomy Patients
The purpose of this study was to evaluate the efficacy and safety of sevoflurane-only Volatile induction and maintenance anesthesia (VIMA) and total intravenous anesthesia (TIVA) using only propofol in adult patients scheduled…
- Trial name
- NCT03094533
- Testing
- TIVA, VIMA
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yeungnam University College of Medicine
Lung Neoplasms
Systemic, Intrapulmonary and Pleural Inflammatory Reaction in Patients Undergoing Thoracic Surgery
Inflammatory reaction in different compartments of the body may have a negative effect on outcome. This study assesses the inflammatory reaction systemically, intrapulmonary and intrapleural by measuring different cytokines.
- Trial name
- NCT00558350
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University Hospital, Basel, Switzerland
Post-thoracotomy Pain Syndrome
IMPACT OF OPERATIVE POSITIONING ON THE DEVELOPMENT OF SHOULDER PAIN AFTER PULMONARY LOBECTOMY BY VATS
The investigators want to be able to show a 66% decrease in the incidence of shoulder pain in the "support" group compared to the "suspension" group.
- Trial name
- POVA (NCT04415242)
- Testing
- positioning
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Lung Cancer
Randomized Study on Effects of Uniportal VATS Versus Triportal VATS
For the treatment of stage I-II NSCLC, two mini-invasive techniques are mostly utilized: uni-portal and three-portal VATS. In the uniportal approach, the injury on a single intercostal space could determine a lower level of pain…
- Trial name
- NCT03240250
- Testing
- VATS uni-portal lobectomy and lymphoadenectomy, VATS three-portal lobectomy and lymphoadenectomy
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Video-assisted Thoracoscopic Surgery, Lung Cancer
Intraoperative Conversion During Video-assisted Thoracoscopy Resection for Lung Cancer Does Not Alter Survival
Anatomical resection with systematic lymph-node dissection is currently the standard of care for the treatment of early stage non-small cell lung cancer.
- Conditions
- Video-assisted Thoracoscopic Surgery, Lung Cancer, Lobectomy, Survival
- Trial name
- ICVATR (NCT04663191)
- Testing
- anatomical resection
- Where
- France
- Volunteers
- 843 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Carcinoma, Non-Small-Cell Lung
The Effect of a Combined Drainage Strategy in Uniportal Upper Lung Lobectomy
Traditional drainage for uniportal video assisted thoracoscopic surgery (VATS) is a routine method, usually with one or two chest tubes at intercostal incisions, but postoperative pain due to the chest tube and unsatisfied…
- Trial name
- NCT04461652
- Testing
- prophylactic air-extraction catheter drainage
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Tongji University
Thoracoscopic Lobectomy, Thoracic Anesthesia
Goal-Directed Fluid Therapy for Thoracoscopic Lobectomy
The investigators aimed to examine the effect of goal-directed fluid therapy (GDFT) compared to conventional fluid therapy in thoracoscopic lobectomy surgery with ERAS protocol on intraoperative pulmonary oxygenation and 30-day…
- Conditions
- Thoracoscopic Lobectomy, Thoracic Anesthesia, Enhanced Recovery After Anesthesia, Lung Cancer
- Trial name
- NCT07050979
- Testing
- Goal-Directed Fluid Therapy (GDFT), Conventional Fluid Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Lung Cancer, Lobectomy
Effect of Pulmonary Rehabilitation in Lung Cancer Survivors
Patients who have surgery to cure lung cancer often have multiple problems at hospital discharge and later on. This includes poor exercise performance and quality of life, breathlessness, pain and tiredness.
- Conditions
- Lung Cancer, Lobectomy, Pulmonary Rehabilitation
- Trial name
- NCT01246297
- Testing
- Pulmonary Rehabilitation, Usual post operative care
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College Healthcare NHS Trust
Lung Cancer
Effects of Open Thoracic Paravertebral Block on Postoperative Analgesia
The study was aimed to assess the effects of open thoracic paravertebral block on postoperative analgesia in patients undergoing open pulmonary lobectomy under general anesthesia.
- Trial name
- NCT03449563
- Testing
- Open TPVB, Ultrasound-guided TPVB
- Volunteers
- 90 people
- Sponsor
- Kunming Medical University
Pulmonary Cancer, Surgery
Effect of SMS Use on Postoperative Respiratory and Cough Exercise Compliance
Aim: This randomized controlled trial study aimed to evaluate the effect of SMS use on compliance with postoperative breathing and coughing exercises and patient satisfaction in patients undergoing pulmonary lobectomy for lung…
- Trial name
- NCT05915221
- Testing
- SMS
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Trakya University
Thoracic Paravertebral Block, Anesthesia Induction
The Impact of Ultrasound-Guided Superficial and Deep Paravertebral Nerve Blocks at the Superior Costotransverse Ligament on Hemodynamics During the Induction Phase of Thoracoscopic Lung Lobectomy: A Multicenter, Double-Blind, Randomized Controlled Trial
This study aims to determine whether performing a paravertebral nerve block at the superficial surface of the superior costotransverse ligament (SCTL) (without needle penetration of the SCTL) is more effective in maintaining…
- Conditions
- Thoracic Paravertebral Block, Anesthesia Induction, Hypotension on Induction
- Trial name
- NCT06841822
- Testing
- SCTL superficial plane block, SCTL deep plane block group
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Lung Cancer, Malnutrition
Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy
Malnutrition is common in patients with lung cancer. In patients with malnutrition risk, the risk of complications is high both in the perioperative, early and late postoperative periods.
- Conditions
- Lung Cancer, Malnutrition, Nutritional Deficiency
- Trial name
- NCT05417672
- Testing
- Nutritional Risk Screening-2002, Nutritional Risk Index, Mini Nutritional Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Lung Cancer, Robotic Thoracic Surgery
Impact of Robotic Approach Compared to VATS and Open Approach on Quality of Life in Patients With Lung Cancer
The aim of the study is to compare quality of life and early and late post-operative pain after anatomical lung resection (lobectomy or segmentectomy) performed by a robotic approach compared to the videothoracoscopic approach…
- Conditions
- Lung Cancer, Robotic Thoracic Surgery, Video-assisted Thoracis Surgery (VATS), Open Thoracotomy Surgery
- Trial name
- QoL (NCT04353349)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Clinico Humanitas