Clinical trials: Pulmonary Lobectomy
Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
Lobectomy is a major, high-risk surgical procedure that in addition to one-lung ventilation (OLV) exerts a potent surgical stress response.
- Conditions
- Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute, Postoperative Pain, Chronic, Infections Postoperative
- Trial name
- NCT05172739
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- University of Crete
Early Stage Non-small-cell Lung Cancer (Stage 1-2)
Assessment of Ergonomics in 3D vs 2D Thoracoscopic Lobectomy
Video-assisted thoracic surgery (VATS) pulmonary lobectomy is currently widely employed as the first treatment option for surgical management of early stage (stage I-II) non-small-cell-lung-cancer (NSCLC).
- Trial name
- NCT03925103
- Testing
- 3D VATS lobectomy, 2D VATS lobectomy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Rome Tor Vergata
Pulmonary Neoplasm
Robot-assisted vs VATS Lobectomy for NSCLC
Robot-assisted thoracoscopic surgery (RATS) was widely used in thoracic surgery, the surgical safety and feasibility of RATS lobectomy for NSCLC has been confirmed.
- Trial name
- RVlob (NCT03134534)
- Testing
- VATS lobectomy, RATS lobectomy
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Ruijin Hospital
Thoracic Paravertebral Block, Anesthesia Induction
The Impact of Ultrasound-Guided Superficial and Deep Paravertebral Nerve Blocks at the Superior Costotransverse Ligament on Hemodynamics During the Induction Phase of Thoracoscopic Lung Lobectomy: A Multicenter, Double-Blind, Randomized Controlled Trial
This study aims to determine whether performing a paravertebral nerve block at the superficial surface of the superior costotransverse ligament (SCTL) (without needle penetration of the SCTL) is more effective in maintaining…
- Conditions
- Thoracic Paravertebral Block, Anesthesia Induction, Hypotension on Induction
- Trial name
- NCT06841822
- Testing
- SCTL superficial plane block, SCTL deep plane block group
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Lung Cancer Stage I
Outside the Cage (OTC) Robotic Lobectomy
This study consists in a prospective pilot study evaluating the feasibility and safety of OTC RATS lobectomies in patients treated for lung cancer.
- Trial name
- OTC-RATS (NCT05832112)
- Testing
- VATS/RATS lobectomy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Operable Early Stage NSCLC by the VATS Approach
Health Related Quality of Life After Video Assisted Thoracoscopic Lobectomy for Lung Cancer
To test the effect of post operative complications on the health related quality of life (HRQOL) after Video Assisted Thoracoscopic Surgery (VATS) for Non-Small Cell Lung Cancer (NSCLC).
- Trial name
- NCT01555502
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Primary Lung Cancer, Benign Lung Disease
SP Thoracic IDE Study
To confirm the safety and performance of the da Vinci SP Surgical System, Instruments and Accessories in pulmonary lobectomy, and in thymectomy procedures.
- Conditions
- Primary Lung Cancer, Benign Lung Disease, Thymoma, Myasthenia Gravis
- Trial name
- NCT05150210
- Testing
- Robotic-Assisted Surgery
- Where
- 6 sites in United States
- Volunteers
- 32 people
- Sponsor
- Intuitive Surgical
Minimally Invasive Surgical Procedures, VATS
Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections
In this study, the reasons for prolonged hospital stay after thoracoscopic (video- or robot-assisted) anatomical lung resections are investigated.
- Conditions
- Minimally Invasive Surgical Procedures, VATS, RATS Surgery, Pulmonary Lobectomy
- Trial name
- PROTRACT (NCT06638645)
- Testing
- VATS/RATS anatomical lung resection
- Where
- 2 sites in Belgium
- Volunteers
- 140 people
- Sponsor
- University Hospital, Ghent
Non Small Cell Lung Cancer
Robot-Assisted vs. Video-Assisted Lobectomy for NSCLC (RAVAR)
Video-assisted thoracic surgery (VATS) has been recommended by clinical guidelines as one of the preferred surgeries for early-stage non-small cell lung cancer (NSCLC) for many years.
- Trial name
- RAVAR (NCT06524427)
- Testing
- Robot-assisted lobectomy, Video-assisted lobectomy
- Where
- 23 sites in China
- Volunteers
- 1,124 people
- Sponsor
- Sun Yat-sen University
Lung Disease
ENDO GIA Stapler With Duet Tissue Reinforcement System (TRS) Used in Pulmonary Resections
The objective of this study is to confirm superiority between a test treatment group using Endo GIA stapler with Duet Tissue Reinforcement System (TRS) and a current international standard of care group using a conventional…
- Trial name
- NCT01241617
- Testing
- Duet TRS, Endo GIA
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG
Lung Neoplasms, Pain
Supplementary Epidural Analgesia in Video-Assisted Thoracic Surgery (VATS) - The SEAVATS Study
Whereas it, in the case of conventional thoracotomy, has been demonstrated that thoracic epidural analgesia is more effective than systemic opioids in terms of pain relief and preservation of postoperative pulmonary function, the…
- Conditions
- Lung Neoplasms, Pain, Immune Suppression
- Trial name
- SEAVATS (NCT02359175)
- Testing
- Bupivacaine in epidural catheter, Fentanyl in epidural catheter, Oral Paracetamol
- Where
- Denmark
- Volunteers
- 161 people
- Sponsor
- Odense University Hospital
Non-small Cell Lung Cancer, Lung Function Decreased
Effects of Nonintubated Thoracoscopic Lobectomy on Lung Protection
A novel nonintubated thoracoscopic technique is promising to enhance recovery after thoracic surgery. However, the effects of nonintubated technique on specific organ protection in not clear yet.
- Conditions
- Non-small Cell Lung Cancer, Lung Function Decreased, Tracheal Intubation Morbidity
- Trial name
- NCT03471884
- Testing
- Nonintubated thoracoscopic lobectomy, Intubated thoracoscopic lobectomy
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- National Taiwan University Hospital
Lung Cancer, Vagus Nerve Injuries
Vagus Nerve Preservation and Chronic Cough in Non-small Cell Lung Cancer Surgery
Lung cancer is the leading cause of cancer death worldwide. Surgical resection is the main treatment for resectable non-small-cell lung cancer (NSCLC), and lobectomy with systemic mediastinal lymph node dissection is the standard…
- Conditions
- Lung Cancer, Vagus Nerve Injuries, Cough
- Trial name
- NCT04923412
- Testing
- Pulmonary branch of vagus nerve preserved, Pulmonary branch of vagus nerve not preserved
- Where
- South Korea
- Volunteers
- 214 people
- Sponsor
- Seoul National University Bundang Hospital
Non-Small Cell Lung Cancer
SEgmentectomy Versus Lobectomy in T1C Non-Small Cell Lung Cancer (SELTIC)
The goal of this clinical trial is to investigate the role of segmentectomy in clinical T1c (2-3 cm) non-small cell lung cancer (NSCLC). The main questions we aim to answer are: 1.
- Trial name
- SELTIC (NCT06646770)
- Testing
- Segmentectomy, Lobectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Istanbul University - Cerrahpasa
Pulmonary Atelectasis
Atelectasis After Pulmonary Lobectomy: The Effect Of Air During One-Lung Ventilation (OLV) On Postoperative Atelectasis
Patients scheduled for lung lobe resection using video assisted thoracic surgery will be randomly assigned to be ventilated with either only oxygen or a mixture of air and oxygen.
- Trial name
- NCT01289691
- Testing
- One Lung Ventilation
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre
Lung Cancer
Ultrasonic Energy for Pulmonary Artery Branch Sealing During VATS Lobectomy
This research program consists of a prospective, multi-institutional Phase 2 trial and an economic cost-effectiveness analysis for the use of ACE+7 in VATS lobectomy/segmentectomy compared to traditional techniques.
- Trial name
- VATS PA-ACE (NCT02719717)
- Testing
- Harmonic Ace+7
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Nonsquamous Nonsmall Cell Neoplasm of Lung, Nonsmall Cell Lung Cancer Stage III
Cisplatin and Pemetrexed With Radiation Followed by Lobectomy
This study is open to patients that have been diagnosed with non-squamous Stage III Non Small Cell Lung Cancer (NSCLC) and will have surgery to remove the tumor.
- Trial name
- CisPemXetSrg (NCT01373463)
- Testing
- Pemetrexed, Carboplatin, Radiation Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Medical University of South Carolina
Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection
Pre-incisional Infiltration With Ropivacaine Plus Triamcinolone for Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection, Segmentectomy, Lobectomy of the Lungs
- Trial name
- NCT07603921
- Testing
- Pre-incisional infiltration with ropivacaine plus triamcinolone, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 346 people
- Sponsor
- Beijing Tiantan Hospital
Nonsmall Cell Lung Cancer
Effects of Acupuncture Stimulation on Systemic Inflammation
60 ASA physical status I or II patients, aged 18-75 years old , scheduled for elective video-assisted thoracoscopic lobectomy surgery,will be randomized into 2 groups,with 30 patients in each group: 1. control group and 2.
- Trial name
- NCT02951611
- Testing
- Acupuncture stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Lung Surgery, Enhanced Recovery After Surgery, ERAS
Evaluation of the Effectiveness of Enhanced Recovery After Surgery (ERAS) Program in Pediatric Lung Surgery
This study aims to evaluate the clinical effectiveness of the Enhanced Recovery After Surgery (ERAS) program for pediatric lung surgery at our institution.
- Conditions
- Lung Surgery, Enhanced Recovery After Surgery, ERAS, Pediatric
- Trial name
- NCT07241286
- Testing
- Enhanced Recovery After Surgery, ERAS
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital