Clinical trials: Pulmonary Nodules
Lung Cancer
Multimedia Patient Education
Objective: To compare changes in patient anxiety levels between groups of patients who either were or were not exposed to an informative multimedia patient education tool, in order to determine how the addition of such a…
- Trial name
- NCT01184534
- Testing
- Video, Questionnaires
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
AI Assisted Detection of Chest X-Rays
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple, Pulmonary Consolidation, Pneumothorax
- Trial name
- AID-CXR (NCT06075836)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Lung Diseases
Image - Navigated Resection of Lung Nodules
This is an open label study lung nodules that are either cancer or non-cancer and who are eligible for surgical resection. Patients will undergo their surgery with the help of the Lung Resection Marker Locator Kit which will…
- Trial name
- NCT04702165
- Testing
- lung resection with Lung Resection Marker Locator Kit
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Navigation Sciences, Inc.
Lung Cancers, Metaverse
Extended Reality (XR)-Assisted CT Localization of Pulmonary Nodules
Extended Reality (XR)-Assisted CT Localization of Pulmonary Nodules
- Conditions
- Lung Cancers, Metaverse, Extended Reality (XR)
- Trial name
- NCT07434167
- Testing
- Extended Reality (XR)-Assisted CT Localization of Pulmonary Nodules
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Lung Abscess
Biomarkers for Diagnosis of Lung Nodules
A need exists for non-invasive testing to aid in clinical decision-making for Computerized Tomography (CT) scan detected lung nodules of indeterminate etiology.
- Trial name
- Nodule (NCT01085864)
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- University of Colorado, Denver
Lung Cancer, Lung; Node
Molecular Analysis of Endoscopic Cytology Samples Supernatant in Pulmonary Nodules
Lung cancer screening is based on low dose CT scan (LDCT), a highly sensitive but poorly specific tool. Complementary specific approaches are thus strongly needed, among which cell-free DNA (cfDNA) genotyping has been proven…
- Trial name
- KOBE (NCT05306912)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Lung Cancer
Evaluating the Pulmonary Nodule With Imaging and Biomarkers
The study aims to determine if there are defining EBUS and confocal endoscopy features as well as exhaled alveolar gas VOC that can discriminate malignant pulmonary nodules or masses from benign etiology, thereby obviating…
- Trial name
- NCT01739881
- Testing
- Olympus Ultrathin Bronchofibervideoscope (XP260F)
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- National University Hospital, Singapore
Pulmonary Nodule
Feasibility and Safety of Remote Robotic Bronchoscopy System in Diagnosis of Peripheral Pulmonary Lesions: a Multicenter, Randomized Controlled, proof-of Concept Trial
Robotic bronchoscopy represents the latest localization technology for peripheral pulmonary nodules, enabling precise and stable manipulation and potentially improving the diagnostic yield of peripheral lung pathologies.
- Trial name
- NCT06613412
- Testing
- Remote Robotic Bronchoscopy system
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Guangzhou Medical University
Lung Nodules, Pneumothorax Iatrogenic Postprocedural
Pneumothorax Safety of Pleural-Depth-Trimmed Hookwires for Lung Nodule Localization
The goal of this observational study is to learn about the pneumothorax risk associated with the Pleural-Depth-Trimmed Hookwire (PDTH) technique in patients undergoing Preoperative CT-Guided Lung Nodule Localization (POCTGL).
- Conditions
- Lung Nodules, Pneumothorax Iatrogenic Postprocedural, Propensity Score Matching
- Trial name
- NCT07300072
- Testing
- Preoperative CT-Guided Lung Nodule Localization with Pleural-Depth-Trimmed Hookwire (PDTH) Technique, Preoperative CTGuided Lung Nodule Localization with Patent Blue Vital Dye (PBVD) Localization Technique
- Where
- Taiwan
- Volunteers
- 1,072 people
- Sponsor
- Chung Shan Medical University
Cancer, Metastasis to Lung
Validation of Low Dose CT for Diagnosis of Lung Nodules
The investigators have developed an extremely low dose computed tomography (CT) protocol that on preliminary testing has an effective dose in the range of two chest radiographs.
- Trial name
- NCT03681873
- Testing
- Extremely Low Dose CT
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pulmonary Nodule Cm
Prognostic Value of miR-21 and miR-486 in Pulmonary Nodule Surgery
This study prospectively evaluated the prognostic value of microRNA-21 (miR-21) and microRNA-486 (miR-486) expression in patients with pulmonary nodules who underwent clock-guided minimally invasive surgery.
- Trial name
- NCT07060287
- Testing
- Clock-Guided Minimally Invasive Surgery
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The First Hospital of Hebei Medical University
Carcinoma, Non-small-cell Lung Cancer
Early Diagnosis of Small Pulmonary Nodules by Multi-omics Sequencing
Analyse immune repertoire and genetic mutations of benign and malignant pulmonary nodule，and evaluate peripheral blood detection for identifying nature of pulmonary nodule.
- Conditions
- Carcinoma, Non-small-cell Lung Cancer, Lung Neoplasm
- Trial name
- NCT03320044
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Lung Cancer (Diagnosis)
Robotic Bronchoscopy for Small Lung Nodules Without a Bronchus Sign
The goal of this observational study is to learn about the diagnostic performance and safety of robotic-assisted bronchoscopy using the Ion Endoluminal System in adults with small lung nodules that do not show a bronchus sign on…
- Trial name
- NCT07862816
- Where
- 4 sites in South Korea
- Volunteers
- 151 people
- Sponsor
- Intuitive Surgical
Lung Neoplasms, Lung Cancer
ELUCIDATE: Enabling Lung Cancer Identification Using Folate Receptor Targeting
This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care.
- Trial name
- Elucidate (NCT04241315)
- Testing
- OTL38 for Injection, Near infrared camera imaging system
- Where
- 12 sites in United States
- Volunteers
- 112 people
- Sponsor
- On Target Laboratories, LLC
Lung Cancer
Technique for Localization of Pulmonary Nodules Using Spy Thoracoscope System
This study will determine the feasibility of the novel Indocyanine Green (ICG) fluorescence localization technique with a Laser fluorescence thoracoscope system.
- Trial name
- NCT02090660
- Testing
- ICG Localization with Spy thoracoscope localization
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Lung Cancer
Performance of Lung MRI Combined to Synthetic CT in the Follow-up of Lung Nodules
Lung cancer screening trials using low-dose chest CT scans have shown a significant reduction of cancer related mortality in subjects at high risk of lung cancer.
- Trial name
- NODU-MR (NCT06825078)
- Testing
- multiparametric MRI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Percutaneous Lung Ablation
A Clinical Trial of Percutaneous Lung Ablation Using Navigational Positioning Robot-assisted Procedures
The purpose of the trial is to exploratively evaluate the safety and efficacy of the Puncture Surgery Navigation and Positioning System for CT-guided percutaneous lung ablation procedures for multiple ground glass nodules.
- Trial name
- NCT07105813
- Testing
- Navigational Positioning System for Puncture Surgery
- Volunteers
- 30 people
- Sponsor
- Xiaolong Yan, Dr.
Lung Nodules
DeepPriorCBCT for Low Dose Lung CBCT Reconstruction
The goal of this clinical trial is to learn if the DeepPriorCBCT model ensure high-quality CBCT image while reducing CBCT radiation dose.
- Trial name
- NCT07035977
- Testing
- Participants will receive a 1/6 views undersampling lung CBCT scan.
- Where
- 5 sites in China
- Volunteers
- 138 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Non-Small Cell Lung Cancer
Station 4L Lymph Node Dissection Versus No Dissection in Clinical Stage I Solid Nodule-Type Invasive NSCLC
This multicenter, prospective, randomized clinical trial will enroll adults aged 18 to 75 years with resectable clinical stage I (T1-T2aN0M0) invasive non-small cell lung cancer presenting as a single solid nodule…
- Trial name
- NCT07801430
- Testing
- Station 4L Lymph Node Dissection
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Fudan University
Lung Cancer, Lung Nodule
SPARC - Screening for Lung Cancer With Platelets Via an AI-enabled RNA-based Classifier
The purpose of this study is to test whether combining a unique analytical approach with changes in platelet RNA expression accurately diagnoses lung cancer.
- Trial name
- SPARC (NCT07460440)
- Testing
- Platelet RNA-based assay
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Utah