Clinical trials: Pulmonary Procedures
Carcinoma
A Non Interventional Study With Doce Onkovis (Docetaxel) Utilized for the Treatment of Cancer
The main purpose of this observational study with Docetaxel is to determine the number of treatment cycles and the quantity of Doce onkovis needed therefore under the special circumstance of ambulant chemotherapy.
- Trial name
- NCT01614002
- Where
- 23 sites in Germany
- Volunteers
- 371 people
- Sponsor
- Onkovis GmbH
Cystic Fibrosis
Early Intervention in Cystic Fibrosis Exacerbation
Individuals with cystic fibrosis (CF) develop chronic lung infections and suffer intermittent acute exacerbations of their lung disease.
- Trial name
- eICE (NCT01104402)
- Testing
- Home lung function and symptom monitoring
- Where
- 3 sites in United States
- Volunteers
- 267 people
- Sponsor
- Johns Hopkins University
Acute Respiratory Failure
The Tele-Rehab MV Cluster Stepped-Wedge Randomized Clinical Trial
To evaluate, through a randomized clinical trial in groups/clusters (stepped wedge), the impact of specific bundles for disability prevention and early rehabilitation, focused on 3 domains (ICU, ward and post-discharge), on…
- Trial name
- Tele-Rehab MV (NCT06343545)
- Testing
- Standard of Care, Disability Prevention and Rehabilitation
- Where
- 20 sites in Brazil
- Volunteers
- 1,916 people
- Sponsor
- Hospital Israelita Albert Einstein
COVID-19
A Comparison of Sample Collection Methods for SARS-COV-2 Antibody Testing
The negative global consequences of the COVID-19 pandemic has prompted efforts to develop efficient laboratory testing protocols that can be quickly scaled in a practical way.
- Trial name
- NCT04537572
- Testing
- comparison of sample collection methods
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Salveo Diagnostics
Pulmonary Embolism
Mechanical Thrombectomy With the FlowTriever Device in Acute Pulmonary Embolism - a Retrospective Analysis
International guidelines recommend intravenous thrombolysis (IVT) for high-risk pulmonary embolism (PE). In high-risk PE where IVT is contraindicated or has failed, surgical embolectomy or catheter-directed intervention (CDI) is…
- Trial name
- NCT06187987
- Testing
- Mechanical thrombectomy, Intravenous thrombolysis
- Where
- Sweden
- Volunteers
- 132 people
- Sponsor
- Kristina Svennerholm
Asthma
HealthSpark 2: Improving Asthma Care for Preschool Children
From a previous community needs survey, we determined that asthma was a particular problem in our community-based research network of child care centers.
- Trial name
- NCT00304304
- Testing
- Asthma education
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Miami
Lung Cancer
A Study to Evaluate Clinical Characteristics of Lung Cancer in Patients With Surgeries and Adjuvant Therapies
The study was designed to evaluate effectiveness of the surgeries and adjuvant therapies after surgeries in the patients with lung malignant tumors
- Trial name
- NCT03421093
- Testing
- Surgeries
- Where
- 10 sites in China
- Volunteers
- 21,777 people
- Sponsor
- West China Hospital
Pulmonary Disease, Chronic Obstructive, Asthma
Smoking Cessation Intervention in Respiratory Inpatients
Prospective, open-label, parallel-group, 52-week trial comparing varenicline in combination with behavioral support with one session of behavioral support alone.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Asthma, Community Acquired Pneumonia
- Trial name
- NCT02922387
- Testing
- Varenicline, Behavioral support
- Volunteers
- 101 people
- Sponsor
- General Hospital of Kavala
COPD, Exacerbation
CRP-guided Antibiotic Treatment in COPD Exacerbations Admitted to the Hospital
Rationale: Acute exacerbations are key events in chronic obstructive pulmonary disease (COPD), resulting in poorer quality of life. Causes include irritants, viruses and bacterial pathogens.
- Conditions
- COPD, Exacerbation, Bronchitis, Sputum
- Trial name
- CATCH (NCT01232140)
- Testing
- CRP-guided antibiotic treatment
- Where
- Netherlands
- Volunteers
- 220 people
- Sponsor
- Medical Center Alkmaar
Non Small Cell Lung Cancer
Preoperative Lymph Node Staging With EBUS-TBNA in Clinical N0 Non Small-cell Lung Cancer
The introduction of modern staging systems has increased the detection of small peripheral lung cancers at an early stage [1]. Stage I non-small-cell lung cancers (NSCLCs) are confined to the lung without lymph node involvement…
- Trial name
- NCT04828850
- Testing
- Endobronchial ultrasound transbronchial needle aspiration lymph node staging
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- European Institute of Oncology
Interstitial Lung Diseases, Systemic Sclerosis Associated Interstitial Lung Disease
A Study Using a Disease Registry to Observe the Long-term Effects of Nintedanib in People With Scleroderma-related Lung Fibrosis
This post-approval registry study is planned to generate data to address remaining questions on long-term effectiveness and to better characterize longer term beneficial effects of Nintedanib in patients with systemic sclerosis…
- Trial name
- NCT07080125
- Testing
- Ofev®
- Where
- Switzerland
- Volunteers
- 2,000 people
- Sponsor
- Boehringer Ingelheim
Asthma
Behavioral Intervention to Increase Physical Activity in Patients with Asthma: Identifying Responders
To identify clinical, personal and anthropometric characteristics among patients with asthma who respond and non-responders to a behavioral intervention to increase the level of physical activity.
- Trial name
- NCT05159076
- Testing
- Behavioral Intervention to Increase Physical Activity
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
Chronic Obstructive Pulmonary Disease
Coping Skills for Patients With Chronic Obstructive Pulmonary Disease (COPD) and Their Caregivers
This study is an NIH-funded clinical trial conducted at Duke University Medical Center and Ohio State University. The purpose of this study is to examine the effects of a telephone-based, care-giver assisted, coping skills…
- Trial name
- NCT00736268
- Testing
- Telephone-based Enhanced Coping Skills Training (CST), Usual Medical Care and COPD education and symptom monitoring (UMC)
- Where
- 2 sites in United States
- Volunteers
- 746 people
- Sponsor
- Duke University
Advanced Lung Carcinoma, Metastatic Malignant Female Reproductive System Neoplasm
A Nurse-Led Intervention for Fear of Progression in Advanced Cancer
This clinical trial focuses on a nurse-led program that is designed to help patients cope with worries, fears, and uncertainty about the future.
- Conditions
- Advanced Lung Carcinoma, Metastatic Malignant Female Reproductive System Neoplasm, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8
- Trial name
- NCT04819997
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- City of Hope Medical Center
Covid19
Efficacy and Safety of Liposomal Lactoferrin in COVID-19 Patients With Mild-to-Moderate Disease and in COVID-19 Asymptomatic Patients
COVID-19 is considered an ongoing international global health problem which already caused 12 million confirmed cases. No specific effective treatment has been identified so far, and available supportive therapies are intended…
- Trial name
- NCT04475120
- Testing
- liposomal lactoferrin, SOC therapy
- Where
- Italy
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Metastatic Solid Tumor, Colon Cancer
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS
The goal of this clinical trial is to determine the safety and efficacy of IP-001 for intratumoral injection administration following thermal ablation of a solid tumor.
- Conditions
- Metastatic Solid Tumor, Colon Cancer, Nonsmall Cell Lung Cancer, Soft Tissue Sarcoma
- Trial name
- INJECTABL-1 (NCT05688280)
- Testing
- 1.0% IP-001 for Injection
- Where
- 16 sites in United States, France and 3 more
- Volunteers
- 42 people
- Sponsor
- Immunophotonics, Inc.
Lung Cancer
Breathe Anew for Lung Cancer Survivorship
Survivorship programs have become an integral component of modern cancer care programs. In Canada, there has been tremendous success for survivorship programs for breast, prostate, and colorectal cancer, however lung cancer…
- Trial name
- BA (NCT03773380)
- Testing
- Breathe Anew Survivorship Program
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Pulmonary Mucormycosis
Efficacy and Safety of Systematic Therapy and Bronchoscopic Interventional Treatment for Pulmonary Mucormycosis
Evaluation of the effectiveness and safety of transbronchoscopic local precision infusion of amphotericin B + transoral nebulized inhalation of amphotericin B + transbronchoscopic interventional debridement + liposomal…
- Trial name
- NCT06495905
- Testing
- transbronchoscopic interventional debridement
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Covid19, SARS-CoV-2 Infection
Identification of Novel Factors Leading to Activated Macrophage Expansion in COVID19 - INFLAME Study
This project aims to undertake a high-resolution analysis of previous cases of COVID19 infection to determine from all available clinical data recorded over the timeline of admission, who might benefit best from specific…
- Trial name
- INFLAME (NCT04903834)
- Testing
- Soton hyperinflammation score, HScore
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Lung Cancer, Lung Diseases
Comparison of Double Lumen Tube Location Verification Techniques in Single Lung Ventilation
The aim of this study was to compare auscultation, fiberoptic bronchoscopy (FOB) and video double lumen tube (VDLT) double lumen tube (DLT) location confirmation techniques in terms of intraoperative tube location confirmation…
- Trial name
- NCT07107893
- Testing
- double lumen tube with video
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Kayseri City Hospital
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