Clinical trials: Pulmonary Procedures
COVID-19 SARS-CoV-2 Infection
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
The purpose of the study is to evaluate whether ibuzatrelvir is effective and safe in adults and adolescents with COVID-19 who do not need to be in the hospital but who are at high risk for progression to severe disease.
- Trial name
- NCT06679140
- Testing
- ibuzatrelvir
- Where
- 256 sites in United States, Argentina and 17 more
- Volunteers
- 2,330 people
- Sponsor
- Pfizer
Respiration
Optical Breath-hold Control System for Image-guided Procedures
The objective or our study is to test the feasibility of a new optical-based breath-hold control (OBC) system for monitoring breath-hold levels and providing patient feedback during CT-guided biopsies of the lung and upper…
- Trial name
- OBC (NCT01062789)
- Testing
- Optical breath-hold control system (OBC)
- Where
- United States
- Sponsor
- Mayo Clinic
Chronic Obstructive Pulmonary Disease, Acute Coronary Syndromes
Screening for Chronic Obstructive Pulmonary Disease in Patients With Acute Coronary Syndromes
Several studies and registries suggested that the concomitant presence of acute coronary syndromes (ACS) and chronic obstructive pulmonary disease (COPD) is significantly associated with poor prognosis.
- Trial name
- SCAP (NCT02324660)
- Testing
- screening test
- Where
- Italy
- Volunteers
- 137 people
- Sponsor
- University Hospital of Ferrara
Lung Carcinoma, Metastatic Malignant Neoplasm in the Lung
Panitumumab-IRDye800 in Detecting Cancer in Participants With Lung Cancer During Surgery
This phase I/II trial studies the best dose and timing of panitumumab-IRDye800 in detecting cancer in participants with lung cancer during the surgery.
- Conditions
- Lung Carcinoma, Metastatic Malignant Neoplasm in the Lung, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8
- Trial name
- NCT03582124
- Testing
- Near-Infrared Fluorescence Imaging, Panitumumab-IRDye800, Pharmacokinetic Study
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
COPD
In This Study, the Sponsor Would Like to Collaborate with Institution and Investigator to Aggregate Participants Data and to Pilot Its Software Algorithm Using Machine Learning and Threshold Based Methods for Predicting Exacerbations and Deterioration Within a 60 Days Period Post-discharge
In this study, the sponsor would like to collaborate with Institution and Investigator to aggregate participants data and to pilot its software algorithm using machine learning and threshold based methods for predicting…
- Trial name
- NCT06798688
- Testing
- A non-invasive cardio-respiratory sensor will be applied on the subjects to measure parameters to identify exacerbations
- Volunteers
- 20 people
- Sponsor
- Respiree Pte Ltd
Pulmonary Disease, Chronic Obstructive, Breathing Exercises
Effects of an Exercise Rehabilitation Programme With a Nasal Inspiratory Restriction Device in COPD Patients
This study evaluates the effects of a nasal restriction device for inspiratory muscle training (FeelBreathe) after 8 weeks of exercise intervention on exercise capacity, quality of life, dyspnea and inspitarotory muscle strength…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Breathing Exercises, Exercise Tolerance
- Trial name
- EPOC_2_0 (NCT03936348)
- Testing
- Exercise training program with and without FB
- Volunteers
- 16 people
- Sponsor
- University of Cadiz
Atrial Fibrillation
Ground-Breaking Electroporation-based Intervention for PERSistent Atrial Fibrillation Treatment (BEAT PERS-AF)
BEAT AF is a randomized controlled trial aiming to assess the efficacy and the safety of pulsed field energy in persistent AF ablation
- Trial name
- BEAT PERS-AF (NCT05418725)
- Testing
- PVI and Linear lesion using PEF, PVI and Linear lesion using CFRF
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 83 people
- Sponsor
- University Hospital, Bordeaux
Coronary Artery Disease
Vascular Function on the First Day After Cardiac Surgery
This study examines the flow mediated dilation (FMD) of the brachial artery before and after cardiac surgery. FMD is measured with ultrasound technique.
- Trial name
- NCT02001090
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Norwegian University of Science and Technology
Elders
Respiratory Training Intervention
This study aims to examine the effect of abdominal diaphragmatic breathing combined with incentive spirometer breathing training on the lung capacity of elderly community residents.
- Trial name
- NCT05969678
- Testing
- breathing training
- Where
- Taiwan
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
PAH, CTEPH
Effects of Pulmonary Rehabilitation on Quality of Life and Health in Pulmonary Arterial Hypertension Patients
Pulmonary hypertension (PH) is a major global health concern, affecting approximately 1% of the world's population. With global aging and increased life expectancy, its incidence continues to rise.
- Trial name
- EPRQoL-PAH (NCT06973382)
- Testing
- Comprehensive Pulmonary Rehabilitation Program, Standard Pulmonary Rehabilitation
- Volunteers
- 84 people
- Sponsor
- Beijing Chao Yang Hospital
Tricuspid Regurgitation (TR)
Categorizing Patient Risk for Tricuspid Regurgitation (TR) Intervention With Admittance Pulmonary Artery Catheter System (APACS)
The study is focused on evaluation of the effectiveness of the Admittance Pulmonary Artery Catheter (PAC) system for assessing the right ventricular (RV) function in patients with tricuspid regurgitation (TR) prior to tricuspid…
- Trial name
- NCT07500025
- Testing
- Right Heart Catheterization
- Volunteers
- 8 people
- Sponsor
- Feldman Cardiology, PLLC
Asthma Attack, Lung Function
Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity
This project will investigate the effectiveness of HEPA air cleaners in reducing indoor air pollution and improving asthma morbidity in children living in East Harlem, New York City (NYC).
- Conditions
- Asthma Attack, Lung Function, Airway Inflammation
- Trial name
- NCT07116460
- Testing
- Austin Air Cleaner
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Columbia University
Smoking ( Cigarette)
Effectiveness of Brief Smoking Cessation Counselling in Pre-Anaesthesia Assessment Clinic
The goal of this clinical trial is to evaluate whether a brief, nurse-delivered smoking cessation intervention can increase pre-operative smoking abstinence and improve perioperative outcomes among adult elective surgical…
- Trial name
- NCT07505147
- Testing
- Nurse-led AWARD brief smoking cessation counselling with active referral and tailored perioperative booklet in the pre-anaesthetic assessment clinic, Usual pre-anaesthetic care without structured smoking cessation
- Where
- Hong Kong
- Volunteers
- 125 people
- Sponsor
- Pok Oi Hospital
Lung Cancer
Auris Robotic Endoscopy System for Bronchoscopy
In this study, the performance related to the use of the novel Robotic Endoscopy Platform during bronchoscopic procedures will be evaluated.
- Trial name
- NCT03497026
- Testing
- Robotic Bronchoscopy Platform
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Auris Health, Inc.
Long COVID, Post-Acute Sequelae of COVID-19
Mind Body Intervention for Long COVID-19
The goal of this study is to determine if a mind-body intervention can help people suffering from symptoms associated with Long COVID.
- Conditions
- Long COVID, Post-Acute Sequelae of COVID-19, COVID Long-Haul
- Trial name
- NCT06045338
- Testing
- Mind Body Intervention #1
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Beth Israel Deaconess Medical Center
Spirometry
The INTERvening for LUNG Health Trial
This research study is being done to find out whether a community health volunteer-delivered, multi-component program can improve lung health for people at risk of chronic respiratory diseases (such as asthma or COPD) in…
- Trial name
- INTERLUNG (NCT07540000)
- Testing
- Community health worker-delivered multi-component respiratory health intervention
- Where
- 2 sites in United States, Nepal
- Volunteers
- 800 people
- Sponsor
- Johns Hopkins University
Asthma-COPD Overlap Syndrome
A Non-interventional Study to Investigate the Current Situation of Asthma-COPD Overlap Syndrome in Patients Over Age 40 With Persistent Airflow Limitation in China
To investigate the distributions of the patients with ACOS, asthma and COPD over age 40 with chronic airflow limitation in China.
- Trial name
- NCT02600221
- Where
- 13 sites in China
- Volunteers
- 2,016 people
- Sponsor
- AstraZeneca
Heart Disease Congenital, Ventricular Septal Defect
Improving Care for Children With Congenital Heart Disease.
Establish a cardiovascular biomarker profile to help screening for congenital heart disease in infants and children as well as use non-invasive cardiac imaging in combination with such profiling to better predict the need for…
- Conditions
- Heart Disease Congenital, Ventricular Septal Defect, Atrial Septal Defect, Patent Ductus Arteriosus
- Trial name
- NCT04667455
- Testing
- Biomarker analysis at enrolment, Biomarker analyses throughout the study
- Where
- Sweden
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Lund University Hospital
Post-COVID-19 Syndrome
Feasibility of a Well-being Promotion Self-management Intervention in Post-COVID-19 Patients
A training comprised of positive psychological interventions set out to improve mental well-being was developed for post-COVID-19 patients. This study aims to evaluate the feasibility and acceptability of this training.
- Trial name
- NCT06658340
- Testing
- Positivity in Post-COVID
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- University of Twente
Venous Thromboembolism
Shared Decision-making Process for Unprovoked vEnous THromboEmbolism Management. (ETHER )
Venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) is a frequent disease and the third most common cause of cardiovascular death in the world after myocardial infarction and stroke.
- Trial name
- ETHER (NCT06731244)
- Testing
- Usual Care Group, shared decision-making process
- Where
- 20 sites in France
- Volunteers
- 2,400 people
- Sponsor
- University Hospital, Brest
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