Clinical trials: Pulmonary Procedures
COVID-19 SARS-CoV-2 Infection
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
The purpose of the study is to evaluate whether ibuzatrelvir is effective and safe in adults and adolescents with COVID-19 who do not need to be in the hospital but who are at high risk for progression to severe disease.
- Trial name
- NCT06679140
- Testing
- ibuzatrelvir
- Where
- 256 sites in United States, Argentina and 17 more
- Volunteers
- 2,330 people
- Sponsor
- Pfizer
Heart Failure
Liberal or Restricted Fluid Intake in Patients With Heart Failure
Heart failure is the most common cause of admission to hospital and is associated with high morbidity and mortality. Treatment options consist of medical- and device treatment and self-care strategies, where fluid restriction has…
- Trial name
- FLUID-HF (NCT05931614)
- Testing
- Free fluid intake
- Where
- Sweden
- Volunteers
- 326 people
- Sponsor
- Region Stockholm
Moderate Chronic Obstructive Pulmonary Disease, Severe Chronic Obstructive Pulmonary Disease
An Exploratory, Observational, Non-interventional, Open Label, Remote Pilot Study to Assess Adherence in COPD Subjects
The purpose of this study is to monitor adherence to a clothing-attached breathing monitor, respiratory patterns, and activity levels in COPD patients, and correlate those respiratory patterns and activity levels with…
- Trial name
- NCT03745547
- Testing
- Adherence to wearing a Spire wearable health monitor
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Spire, Inc.
Type 1 Diabetes, Allergic Rhinitis
Intervention in Chronic Pediatric Patients and Their Families.
This project consists of a psychological intervention in patients and their families with different chronic diseases in order to carry out a comparative study between medical pathologies to know which are the protective or risk…
- Conditions
- Type 1 Diabetes, Allergic Rhinitis, Allergic Asthma, Asthma
- Trial name
- FACTORADAPT (NCT04476433)
- Testing
- Ten Vida (10Vida)
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Bronchiectasis
Bronchiectasis: Evaluation of an Educational Intervention
A study of an educational intervention of primary care practice physicians to assist in the identification of patients who have Bronchiectasis and to assess the effectiveness of the specific didactic educational intervention…
- Trial name
- NCT01315626
- Testing
- Primary Care Educational event
- Where
- United States
- Sponsor
- Hill-Rom
Non Small Cell Lung Cancer Stage, Small Cell Lung Cancer
Exercise in Advanced Stage Lung Cancer Patients
The aim of this study is to evaluate the effect of twelve weeks of a physical and psycho-social program consisting of: supervised, structured exercise training in a group of advanced lung cancer patients (cardio and strength…
- Trial name
- EXHALE (NCT01881906)
- Testing
- Usual care, Exercise
- Where
- Denmark
- Volunteers
- 219 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COVID-19
Complementary Intervention for COVID-19
Boswellia Serrata gum and Licorice extract are two nutritional agents that have pharmacological actions that could support the medical intervention for COVID-19.
- Trial name
- NCT04487964
- Testing
- Licorice extract
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Egyptian Biomedical Research Network
Asthma
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
The aim of this study is to evaluate the efficacy of depemokimab administered as an adjunctive therapy, in participants with Type 2 asthma at risk of exacerbations compared to the guideline recommended standard of care (SoC).
- Trial name
- MODIFY (NCT07456033)
- Testing
- Depemokimab
- Where
- 17 sites in United States, United Kingdom
- Volunteers
- 456 people
- Sponsor
- GlaxoSmithKline
Hypertension, Pulmonary
A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
The purpose of the study is to enable participants with pulmonary hypertension (PH) currently treated with study intervention(s) in a clinical study (parent studies [NCT03422328, NCT03904693,NCT04565990, NCT02932410, NCT03492177…
- Trial name
- PLATYPUS (NCT05179876)
- Testing
- Macitentan, Selexipag, Macitentan/Tadalafil FDC
- Where
- 45 sites in Belarus, Belgium and 11 more
- Volunteers
- 280 people
- Sponsor
- Actelion
Pulmonary Surgical Procedures
Loco-regional Anaesthesia in Video or Robot-assisted Thoracic Pulmonary Surgery
Currently, there is no data on the part and type of Loco-regional Anaesthesia used for Video or Robot-assisted Thoracic Pulmonary Surgery.
- Trial name
- ARTIST (NCT05126524)
- Testing
- NO INTERVENTION
- Where
- 26 sites in France
- Volunteers
- 456 people
- Sponsor
- Société Française d'Anesthésie et de Réanimation
Lung Cancers, Pulmonary Lymphomas
PET/CT-Based Image Analysis and Machine Learning of Hypermetabolic Pulmonary Lesions
First, we analyse the types, imaging findings and relevant treatment responses based on PET/CT to complete a more comprehensive view of pulmonary lymphomas.
- Conditions
- Lung Cancers, Pulmonary Lymphomas, Pulmonary Metastases, Benign Pulmonary Diseases
- Trial name
- NCT06602674
- Testing
- Observe the medical images, Feature extraction
- Where
- China
- Volunteers
- 647 people
- Sponsor
- Ruijin Hospital
Surgical Procedures, Operative, Anaesthesia
POPULAR: POst-operative PULmonary Complications After Use of Muscle Relaxants in Europe
International multicenter observational study of a random-sample cohort of patients undergoing any in-hospital surgical procedure under general or regional anaesthesia during a continued 14-day period of recruitment.
- Trial name
- POPULAR (NCT01865513)
- Where
- 2 sites in Germany, Sweden
- Volunteers
- 22,000 people
- Sponsor
- European Society of Anaesthesiology
Long COVID
A Decentralized, Randomized Phase 2 Efficacy and Safety Study of Nirmatrelvir/Ritonavir in Adults with Long COVID.
This decentralized trial is a Phase 2, 1:1 randomized, double-blind, superiority, placebo-controlled study in an anticipated 100 non-hospitalized highly symptomatic adult participants with long COVID.
- Trial name
- NCT05668091
- Testing
- Nirmatrelvir, Ritonavir
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Harlan M Krumholz
Asthma
Primary Care Implementation and Evaluation of Coach McLungs
The goal of this study is to evaluate the implementation of the Coach McLungsSM shared decision making (SDM) intervention into primary care across a large healthcare system.
- Trial name
- NCT05059210
- Testing
- Coach McLungs Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Wake Forest University Health Sciences
Acute Respiratory Distress Syndrome, Acute Lung Injury
Comparison of Two Methods to Estimate the Lung Recruitment
In this study the investigators aim to compare two common methods to estimate the lung recruitment in ALI/ARDS patients.
- Trial name
- NCT00759590
- Testing
- CT scan and Pressure volume curve
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Policlinico Hospital
Chronic Obstructive Pulmonary Disease
Efficacy & Safety of Dry Powder Ivy Extract (Syrup Prospan) Versus NAC Among COPD Patients
As the third global leading cause of death, Chronic Obstructive Pulmonary Disease (COPD) affects more than 300 million people worldwide. These patients suffer from 0.5-3.5 exacerbations per year on average.
- Trial name
- SyProNAC (NCT06377410)
- Testing
- Syrup Prospan, N-Acetylcysteine
- Where
- 2 sites in Malaysia
- Volunteers
- 100 people
- Sponsor
- National University of Malaysia
Chronic Obstructive Pulmonary Disease (COPD), Asthma
The SENSOR Study: A Mixed-methods Study of SElf-management Checks to Predict exacerbatioNs of Pseudomonas Aeruginosa in Patients With Long-term reSpiratORy Conditions
The World Health Organisation predicts that lung disease will be the World's third largest killer in the future. This research project is looking to see whether the concept of a "home hospital" using the latest gadgets and iPad…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma, Bronchiectasis
- Trial name
- SENSOR (NCT02458807)
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Pulmonary Embolism
Thrombolytic and Interventional Treatment of Pulmonary Embolism
Pulmonary embolism (PE) is a pulmonary vascular disease that seriously endangers human health. It has the characteristics of high morbidity, high mortality, high misdiagnosis rate and low detection rate.
- Trial name
- NCT03886194
- Testing
- interventional treatment in pulmonary
- Where
- China
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Lung Cancer
CT-Controlled Advanced Navigation Techniques for Transbronchial Pulmonary Lesion Access; Evaluation of Electromagnetic Navigation Based Diagnostic Yield
In this clinical trial we will investigate the diagnostic yield of a combination of commercially available imaging and navigation techniques for reaching peripheral lung lesions.
- Trial name
- CONTROL-E (NCT03355586)
- Testing
- Electromagnetic navigation
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Venous Thromboembolism, Deep Venous Thrombosis
The Protrieve PROTECTOR Study
The Protrieve PROTECTOR Study is a prospective, single-arm, multicenter study of the Protrieve Sheath.
- Trial name
- PROTECTOR (NCT06495996)
- Testing
- Percutaneous mechanical thrombectomy (PMT)
- Where
- 15 sites in United States
- Volunteers
- 66 people
- Sponsor
- Inari Medical
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