Clinical trials: Pulmonary Procedures
Asthma
Hypertonic Saline as Add on Therapy in Preschool Children With Acute Wheezing Attack.
To investigate the efficacy of adding Inhaled Hypertonic Saline treatment (HS) for 1-6 year old children with "asthmatic" attack presenting to Emergency Department (ED).
- Trial name
- NCT01073527
- Testing
- hypertonic saline-salbutamol combination, Normal saline-salbutamol combination
- Where
- Israel
- Volunteers
- 41 people
- Sponsor
- Wolfson Medical Center
Chronic Lung Infection With Pseudomonas Aeruginosa in Cystic Fibrosis
Evaluation of Lung Clearance Index in Cystic Fibrosis (CF) Patients, Infected With P.Aeruginosa
The purpose of the study was to evaluate lung clearance index (LCI) by a standardized procedure in a well characterized study setting and to assess feasibility of LCI as a more sensitive method than forced expiratory volume at 1…
- Trial name
- ELIXIR (NCT02248922)
- Testing
- TIS or TIP
- Where
- 6 sites in Germany
- Volunteers
- 17 people
- Sponsor
- Novartis Pharmaceuticals
Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma
Understanding New Cachexia Subtypes Through Observational Epidemiological Research
The UNCOVER study is a longitudinal observational cohort focused on patients at high risk for cancer cachexia. At Kaiser Permanente Northern California, up to 800 individuals with advanced or unresectable non-small cell lung…
- Conditions
- Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma, Advanced Pancreatic Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8
- Trial name
- UNCOVER (NCT07776353)
- Testing
- Biospecimen Collection, Computed Tomography, Electronic health record review
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Kaiser Permanente
Preterm Infants, Neonatal Respiratory Distress Syndrome
Comparison of the Need Of Mechanical Ventilation Between Less Invasive Surfactant Administration (LISA) and Conventional INSURE (Intubation-Surfactant Administration-Extubation) Methods in Spontaneously Breathing Preterm Infants With Respiratory Distress Syndrome
Brief Summary of the Study This randomized controlled trial aims to compare the need for mechanical ventilation between Less Invasive Surfactant Administration (LISA) and the conventional INSURE (Intubation, Surfactant…
- Conditions
- Preterm Infants, Neonatal Respiratory Distress Syndrome, Need for Mechanical Ventilation
- Trial name
- NCT07910539
- Testing
- Intervention Name: Poractant alfa (surfactant) administered by the INSURE method
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Fatima Jinnah Medical University
Chronic Obstructive Pulmonary Disease
Quality of Life in Pulmonary Rehabilitation: A Social Identity Based Intervention
The main aim of pulmonary rehabilitation is to improve the quality of life of patients that have been diagnosed with chronic lung disease.
- Trial name
- NCT02288039
- Testing
- Social Identity goal-based Intervention
- Where
- United Kingdom
- Volunteers
- 84 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Pulmonary Disease, Chronic Obstructive
Comparative Study of Error Rates Between ELLIPTA® Dry Powder Inhaler (DPI) and Other DPIs
For effective drug delivery using inhalation route, it is important to use the inhalers correctly. This open-label study will evaluate the error rates during the use of ELLIPTA DPI, alone or in combination, in comparison with…
- Trial name
- NCT03114969
- Testing
- Relvar ELLIPTA, Symbicort TURBUHALER, Seretide DISKUS
- Where
- 13 sites in Netherlands, United Kingdom
- Volunteers
- 450 people
- Sponsor
- GlaxoSmithKline
Gender Differences, Musculoskeletal Assessment
Gender Differences in Musculoskeletal Assessment Methods in Patients With Chronic Mechanical Low Back Pain
This study is an observational test-retest study designed to investigate the effect of gender on core strength, balance, spinal mobility, and hamstring flexibility in patients with chronic non-specific low back pain (NS-LBP).
- Conditions
- Gender Differences, Musculoskeletal Assessment, Chronic, Low Back Pain
- Trial name
- NCT07018154
- Testing
- Musculoskeletal Assessment
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Non-small Cell Lung Cancer, Metastatic Colorectal Cancer
A Post-marketing Surveillance to Assess the Safety and Effectiveness of Zirabev in Domestic Patients With Various Cancer
This is a prospective, single-arm, open-label, non-interventional, multicenter, post-marketing surveillance to assess the safety and effectiveness of Zirabev(Bevacizumab biosimilar) in domestic patients with non-small cell lung…
- Conditions
- Non-small Cell Lung Cancer, Metastatic Colorectal Cancer, Metastatic Breast Cancer, Metastatic Kidney Cancer
- Trial name
- NCT04889495
- Testing
- Zirabev
- Sponsor
- Pfizer
Asthma
A Patient-Centered Asthma Management Communication Intervention for Rural Latino Children
The purpose of this research is to develop and evaluate an mHealth communication intervention designed to improve asthma medication adherence amongst rural Latino children in South Carolina.
- Trial name
- NCT04633018
- Testing
- AsthmaMD mobile application, Usual care
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Cancer
Effectiveness of A Multi-Component Self-Management Intervention for Anxiety and Respiratory-Related Symptoms in Patients With Lung Cancer
The study aims to examine the effectiveness of M-RDSI (Mindfulness-Respiratory Distress Symptom Intervention) in Hong Kong (HK) Chinese patients with lung cancer (LC).
- Trial name
- NCT07782710
- Testing
- M-RDSI, RDSI, Usual Care
- Volunteers
- 189 people
- Sponsor
- The Hong Kong Polytechnic University
Ultrasonography, Pediatrics
Intraoperative Lung Ultrasound in Pediatric Patients
Investigators hypothesized that perioperative lung ultrasound would be beneficial in pediatric patients undergoing cardiac surgery compared to those who did not receive lung ultrasound.
- Conditions
- Ultrasonography, Pediatrics, Perioperative Period, Lung
- Trial name
- LUS (NCT02535013)
- Testing
- Lung ultrasound
- Where
- South Korea
- Volunteers
- 122 people
- Sponsor
- Seoul National University Hospital
Well-Being, Psychological
Protective Anesthesiological Management Procedure Imposes Control on Respiratory Comlications
Anesthetic effects, surgery, and invasive mechanical intubation can impair respiratory function during general anesthesia. The risk factors for postoperative pulmonary complications (PPCs) include the type of surgery and…
- Trial name
- NCT06282003
- Testing
- The procedure of protective lung ventilation
- Where
- Croatia
- Volunteers
- 53 people
- Sponsor
- Masa Kontic
Respiratory Failure
The Use of Vibrational Methods of Influencing the Lungs to Restore Their Functional State
There will be formed of groups for application of vibration methods on the lungs: the method of vibroacoustic lung massage using the "BARK VibroLUNG" device; the method of oscillating PEP therapy using Acapella DH Green; the…
- Trial name
- NCT05159401
- Testing
- prevention of respiratory failure
- Where
- Russia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Petrovsky National Research Centre of Surgery
End-stage Renal Disease
IVC and Lung Ultrasound B-lines Guided Decongestion in Critically Ill ESKD Patients With Heart Failure
The objectives of this trial are to determine whether, in critically ill ESKD patients randomization to fluid removal guided by lung and inferior vena cava ultrasound, compared to standard care, leads to Improved pulmonary…
- Trial name
- NCT06373575
- Testing
- Lung and inferior vena cava ultrasound guidance, Conventional protocol guidance
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Asthma
Motivational Interviewing for Medication Adherence in Asthma
The high burden of asthma appears to be related to poor asthma control, which is associated with more frequent asthma symptoms, greater bronchodilator use and functional impairment, and worse pulmonary function.
- Trial name
- NCT01132430
- Testing
- Motivational interviewing, Usual care
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Coronavirus Infection, COVID
Cytokine Adsorption in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation
In December 2019 in the city of Wuhan in China, a series of patients with unclear pneumonia was noticed, some of whom have died of it.
- Conditions
- Coronavirus Infection, COVID, SARS-CoV 2, Respiratory Failure
- Trial name
- CYCOV-II (NCT04385771)
- Testing
- vv-ECMO + cytokine adsorption (Cytosorb adsorber), vv-ECMO only (no cytokine adsorption)
- Where
- 3 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Dr. Alexander Supady
Chronic Obstructive Pulmonary Disease (COPD), Bronchial Asthma
Adherence to Inhaled Therapy - a Globally Overlooked Problem in Patients With Chronic Obstructive Pulmonary Disease and Bronchial Asthma
Comprehensive assessment and interventions to promote adherence to inhaled therapy in patients with bronchial asthma and chronic obstructive pulmonary disease involving health care professionals caring for these patients in…
- Trial name
- NCT07183657
- Testing
- Education in inhalation technique
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- Charles University, Czech Republic
Breathlessness, Dyspnea
Improving Management of Breathlessness in Patients With Lung Cancer
Many individuals with lung cancer experience debilitating breathlessness at some point during the course of their illness. Unfortunately, few interventions exist to treat this distressing symptom of cancer.
- Conditions
- Breathlessness, Dyspnea, Lung Cancer
- Trial name
- NCT01937637
- Testing
- Cognitive Behavioral Intervention for Breathlessness
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Massachusetts General Hospital
Noninvasive Ventilation, Chronic Disease Lung
Behavioural Intervention in Mechanically Ventilated Patients
Background: Non-invasive ventilation at home for chronic respiratory failure due to different etiologies has proven effective regarding mortality and quality of life.
- Trial name
- NCT03932175
- Testing
- Intervention group
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- Hospital Clinic of Barcelona
COPD
A Home-based Module to Promote Mindful Breathing Awareness for COPD Patients
The purpose of this study is to develop a mindful breathing module to an already effective and developed home based rehabilitation program for guiding COPD patients in a mindful breathing practice and further palliate…
- Trial name
- NCT04517500
- Testing
- Home-based pulmonary rehabilitation program, Mindful breathing module, Health coaching
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Mayo Clinic
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