Clinical trials: Pulmonary Procedures
Non-small Cell Lung Cancer, Cardiovascular Complication
Early Specialized Cardiovascular Intervention Based on Impedance Cardiography in Locally Advanced Non-small Cell Lung Cancer Patients
This is a prospective, randomized, controlled, multi-center phase III clinical trial that intends to evaluate the role of early cardiovascular intervention based on impedance cardiography in patients with locally advanced…
- Trial name
- NCT04980716
- Testing
- Multiple cardiovascular drugs related to "Golden Triangle"
- Where
- China
- Volunteers
- 524 people
- Sponsor
- Sun Yat-sen University
Pulmonary Disease, Chronic Obstructive
The Effects of Inhaled Budesonide-formoterol-glycopyrronium in Moderate-to-severe COPD
The fixed-dose combination product Budesonide/Glycopyrronium/Formoterol Fumarate Inhalation Aerosol, BGF pMDI and dual combination product Glycopyrronium/Formoterol Fumarate Inhalation Aerosol , GFF pMDI are developed for…
- Trial name
- OCT (NCT04675463)
- Testing
- BGF Inhalation Aerosphere, GFF Inhalation Aerosphere
- Where
- China
- Volunteers
- 50 people
- Sponsor
- ShiYue Li
Covid19
Evaluation of Prognostic Modification in COVID-19 Patients in Early Intervention Treatment
The present study is designed for patients with mild COVID-19 phase, to demonstrate if there is a modification in the clinical evolution greater than or equal to 25% in their symptoms, implemented in two groups of patients under…
- Trial name
- NCT04673214
- Testing
- Azithromycin / Ivermectin / Ribaroxaban / Paracetamol, Azithromycin / Ribaroxaban / Paracetamol
- Where
- Mexico
- Volunteers
- 114 people
- Sponsor
- Gilberto Cruz Arteaga
COVID-19 Infection
Breathing Techniques and Meditation for Health Care Workers During COVID-19 Pandemic
This phase I trial investigates breathing techniques and meditation for health care workers during COVID-19 pandemic. Breathing techniques and medication may help manage stress and improve lung health.
- Trial name
- NCT04482647
- Testing
- Media Intervention, Meditation Therapy, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Ablation Techniques, Atrial Fibrillation (Paroxysmal)
Paroxysmal Atrial Fibrillation Repeat Ablation Strategies With Durably Isolated Pulmonary Veins
This study looks at participants who have undergone an ablation procedure for atrial fibrillation previously, and atrial fibrillation has occurred and a second ablation procedure is needed.
- Conditions
- Ablation Techniques, Atrial Fibrillation (Paroxysmal), Quality of Life
- Trial name
- PARADISO (NCT07910825)
- Testing
- Tailored Strategy, Control Strategy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Psychological Distress, Well-being
The Effectiveness of a CA-CBI on Psychological Distress of University Students During the COVID-19 Pandemic
The effectiveness study for Culturally Adapted Cognitive Behavioral Intervention will be conducted with university students to measure if this intervention if effective for decreasing the university students' psychological…
- Trial name
- NCT04858789
- Testing
- Culturally Adapted Cognitive Behavioral Intervention (CA-CBI)
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Koç University
Asthma
Effects of Educational Intervention on Long-Term Outcomes of Hospitalized Children With Asthma
The investigators hypothesize that reinforced asthma education improves long-term outcomes in children with asthma. Specific Aims and Objectives: 1. To determine the retention rate of parental knowledge about asthma; 2.
- Trial name
- IHOP (NCT01447459)
- Testing
- Reinforced Asthma Education
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Louisville
Carcinoma, Non-Small-Cell Lung
Nab-Paclitaxel in Combination With Carboplatin as First-line Therapy in Patients With NSCLC
This is a single-arm non-interventional study (NIS) to evaluate the effectiveness, safety and quality of life (QoL) in patients with advanced NSCLC receiving the combination of nab-paclitaxel and carboplatin as first line…
- Trial name
- NEPTUN (NCT02799862)
- Testing
- Nab-Paclitaxel, Carboplatin
- Where
- Germany
- Volunteers
- 408 people
- Sponsor
- iOMEDICO AG
Pulmonary Disease, Chronic Obstructive
A Comparative Effectiveness Study of Mortality Outcomes and Related Cardiopulmonary Events Among a Cohort of Chronic Obstructive Pulmonary Disease (COPD) Patients Who Initiate Breztri and Multiple Inhaler Triple Therapy (MITT) in the United States (US)
Patients with chronic obstructive pulmonary disease (COPD) have elevated risk of mortality and cardiopulmonary events, particularly following exacerbations.
- Trial name
- SKOPOS:MAZI (NCT06744374)
- Testing
- BGF, MITT
- Where
- United States
- Volunteers
- 22,369 people
- Sponsor
- AstraZeneca
Malaria, Diarrhea
Partnership and Dignity: a Mixed-methods Survey on Supporting and Retaining Uganda's Village Health Teams
For more than a decade, Uganda's Ministry of Health has led a community health worker program model in which Village Health Teams (VHTs), cadres of unpaid volunteers, are assigned the task of delivering preventative health…
- Conditions
- Malaria, Diarrhea, Pneumonia
- Trial name
- NCT02374580
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- George Washington University
Breast Carcinoma, Colorectal Carcinoma
HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics
This clinical trial studies the effectiveness of a web-based cancer education tool called Helping Oncology Patients Explore Genomics (HOPE-Genomics) in improving patient knowledge of personal genomic testing results and cancer…
- Conditions
- Breast Carcinoma, Colorectal Carcinoma, Lung Carcinoma, Malignant Solid Neoplasm
- Trial name
- NCT04905082
- Testing
- Best Practice, Educational Intervention, Genomic Profile
- Where
- United States
- Volunteers
- 465 people
- Sponsor
- City of Hope Medical Center
COPD, Cancer
SELF - BREATHE for Chronic Breathlessness
Semi-structured qualitative interviews will be conducted to understand key factors that would enable / facilitate patients with chronic breathlessness to potentially use an online breathlessness intervention (SELF-BREATHE).
- Conditions
- COPD, Cancer, Heart Failure, Interstitial Disease
- Trial name
- NCT04466020
- Testing
- Qualitative research interviews to be conducted
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- King's College Hospital NHS Trust
Non-small Cell Lung Cancer
Real-world Treatment Patterns and Associated Outcomes in Patients With Resectable Early-stage Non-small Cell Lung Cancer
This is a non-interventional, multi-country, multicentre, retrospective study designed to determine the treatment patterns and associated survival rate in patients with primary stage IA to IIIB resectable NSCLC diagnosed between…
- Trial name
- THASSOS-INTL (NCT04808050)
- Where
- 25 sites in Australia, Egypt and 5 more
- Volunteers
- 748 people
- Sponsor
- AstraZeneca
Smoking Cessation, Lung Cancer
Implementation of a System-level Tobacco Treatment Intervention
The proposed study plans to adapt and study the implementation and effectiveness of integrating Clinical and Community Effort Against Secondhand smoke Exposure (CEASE) into the thoracic oncology setting using mixed methods.
- Trial name
- NCT02816697
- Testing
- CEASE, Usual Care Tobacco Treatment Services
- Where
- 2 sites in United States
- Volunteers
- 263 people
- Sponsor
- Dana-Farber Cancer Institute
Lung Carcinoma
A Restorative Justice-Based Lung Cancer Screening Decision-Making Support Intervention Tailored for Black Individuals to Increase Lung Cancer Screening Among Black Community Members, RESTORE Trial
This clinical trial develops and studies whether a restorative justice-based lung cancer screening (LCS) decision-making support intervention tailored for Black individuals increases LCS among Black community members.
- Trial name
- NCT07490860
- Testing
- Educational Intervention, Survey Administration, Interview
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Non-small Cell Lung Cancer
Osimertinib Combined With Chemotherapy in Patients Who Had Distant Recurrence After Adjuvant Osimertinib for EGFRm Resectable SIB-IIIA NSCLC.
This study is designed as a multi-cohort trial based on various patient biomarkers study with the potential to include new study treatment in the future.
- Trial name
- REVIVE (NCT07279935)
- Testing
- Osimertinib+cisplatin or carboplatin + pemetrexed Edit
- Where
- 32 sites in China
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
COVID-19, Physiotherapy
Lung Recruitment Device for COVID-19
INTRODUCTION As there is no specific cure in the treatment of COVID-19 at this moment of the pandemic, supportive management including mechanical ventilation is the core management in an intensive care unit (ICU).
- Trial name
- NCT04361435
- Testing
- Chest physiotherapy using a non-invasive oscillating device
- Volunteers
- 50 people
- Sponsor
- St. Justine's Hospital
Tuberculosis
The Correlate of Risk Targeted Intervention Study
Effective tuberculosis (TB) control requires that people who progress from latent Mycobacterium tuberculosis (MTB) infection (LTBI) to TB disease are identified and treated before they infect others.
- Trial name
- CORTIS (NCT02735590)
- Testing
- Isoniazid, Rifapentine
- Where
- 5 sites in South Africa
- Volunteers
- 2,927 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Lung Neoplasms
Active Cycle of Breathing Techniques on Respiratory Distress Symptom Cluster
This study was designed as a randomized, control group, experimental study to examine the effect of Active Cycle of Breathing Techniques application on respiratory distress symptom cluster in patients with lung cancer.
- Trial name
- NCT05879354
- Testing
- Active Cycle of Breathing Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Maltepe University
Cancer Patients
The Risk Factors for Acute Radiation Pneumonitis in Patients With Prior Receipt of Immune Checkpoint Inhibitors
The purpose of this non-interventional study is to collect data on the risk factors for acute radiation pneumonitis in patients with prior receipt of immune checkpoint inhibitors.
- Trial name
- NCT05219851
- Testing
- Cancer patients underwent thoracic intensity-modulated radiotherapy
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Hubei Cancer Hospital
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