Clinical trials: Pulmonary Procedures
Acute Respiratory Failure With Hypoxia, Acute Respiratory Distress Syndrome
The Acute Respiratory Intervention StudiEs in Africa (ARISE-AFRICA) Study
The dearth of Intensive care units in low resource settings portends for poor outcomes amongst patients with acute hypoxemic respiratory failure (AHRF) .
- Conditions
- Acute Respiratory Failure With Hypoxia, Acute Respiratory Distress Syndrome, Acute Lung Injury
- Trial name
- ARISE-AFRICA (NCT04693403)
- Testing
- HFNC, CPAP, Standard Oxygen
- Where
- 17 sites in Uganda
- Volunteers
- 705 people
- Sponsor
- Makerere University
Breathing Exercises
Deep Breathing Exercise With Incentive Spirometer Started in the Preoperative Period
Open cardiac surgery is an important treatment method that is frequently used in the treatment of complicated atherosclerotic ischemic heart disease and heart valve diseases.
- Trial name
- NCT05428722
- Testing
- deep breathing exercises with a incentive spirometer
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara University
ARDS, Human, Lung, Wet
Treatment of ARDS With Instilled T3
It is hypothesized that instillation of Liothyronine Sodium (T3) into the airspace will be safe, well tolerated, and will increase alveolar fluid clearance and decrease inflammation in patients with ARDS, reflected in improved…
- Conditions
- ARDS, Human, Lung, Wet, Thyroid, Pulmonary Edema
- Trial name
- ARDS+T3 (NCT04115514)
- Testing
- Liothyronine Sodium (T3+0.9% sodium chloride) modified formulation specifically for airway instillation., Non-intervention
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Minnesota
Cardiac Disease, Respiratory Disease
Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)
Subjects will use the Gabi system on a daily basis for 3 months, each time the subject is resting or asleep. The Gabi system will recording the SpO2, pulse rate, respiratory rate and movements of the subject.
- Conditions
- Cardiac Disease, Respiratory Disease, Congenital Cardiac Defect, Cardiovascular Diseases
- Trial name
- BRIDGE (NCT05319236)
- Testing
- Gabi System
- Where
- 4 sites in United States, Belgium
- Volunteers
- 101 people
- Sponsor
- Gabi SmartCare
Pulmonary Embolism, Venous Thromboembolism
Risk of Pulmonary and Venous Thromboembolism in Pregnancies After in Vitro Fertilization
Occurrence of venous thromboembolism during in Vitro Fertilization (IVF) pregnancies has been reported in numerous case reports and in two small consecutive series.
- Trial name
- NCT01524393
- Where
- Sweden
- Volunteers
- 140,458 people
- Sponsor
- Danderyd Hospital
Chronic Disease, Lung Diseases, Obstructive
Home-based Exercise Training for COPD Patients (HOMEX-2)
The aim of this study is to assess the effectiveness of a home-based exercise training program in COPD patients who did not participate in an inpatient or outpatient rehabilitation program within the last 2 years.
- Conditions
- Chronic Disease, Lung Diseases, Obstructive, Respiratory Disease
- Trial name
- NCT03654092
- Testing
- Exercise
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Tobacco Use Cessation, Tobacco Use Disorder
Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid
Coal miners in Central Appalachia have among the highest rates of tobacco and nicotine product (TNP) use of any occupational group and face elevated rates of lung cancer and coal workers' pneumoconiosis ("black lung").
- Conditions
- Tobacco Use Cessation, Tobacco Use Disorder, Nicotine Dependence, Smokeless Tobacco Use
- Trial name
- NCT07694492
- Testing
- QuitAid (pharmacist-delivered MTM), Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Asthma
To Evaluate Newly Developed Pictogram Cards and Their Utility in Improving Inhaler Techniques in Asthmatic Patients
To evaluate newly developed pictogram cards and their utility in improving inhaler techniques in asthmatic patients.
- Trial name
- NCT06562764
- Testing
- Counselling by the Trained Pharmacist, Pictograms Cards and Counselling by the Trained Pharmacist
- Where
- Pakistan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Islamia University of Bahawalpur
Asthma
Randomised Controlled Trial of a Multi-faceted Community-based Intervention to Improve Asthma in Children
The objectives of this trials are to demonstrate, in children with poorly controlled asthma, that an intervention to increase the awareness and the impact of poor asthma control among parents and physicians of affected children…
- Trial name
- NCT00238888
- Testing
- asthma control awareness, Usual care
- Where
- Canada
- Volunteers
- 298 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Asthma
A Multifaceted Prompting Intervention for Urban Children With Asthma
The overall goal of this project is to evaluate whether a multifaceted prompting intervention, administered in the urban primary care office setting, reduces morbidity among urban children with asthma.
- Trial name
- PAIR-UP (NCT01105754)
- Testing
- Multifaceted Prompting Intervention MPI
- Where
- United States
- Volunteers
- 638 people
- Sponsor
- University of Rochester
COPD, HIV/AIDS
High-quality COPD Care for People With Immune Dysfunction Through Proactive E-consults
This study examines an intervention to promote effective, evidence-based care and de-implement inappropriate therapies for COPD in HIV-infected (HIV+) patients.
- Trial name
- ACHIEVE (NCT03856879)
- Testing
- Proactive E-consult
- Where
- 7 sites in United States
- Volunteers
- 270 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Hypertension, Pulmonary, Hemolysis
Use of Inhaled Nitric Oxide to Prevent Pulmonary Hypertension Associated to Stored Blood Transfusion
The objective of this study is to assess if prolonged storage time of a packed red blood cell unit may cause pulmonary vasoconstriction after transfusion, in a susceptible population such as cardiac surgery patients.
- Trial name
- NCT02217683
- Testing
- Nitric Oxide
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Atelectasis
The Effect of Oscillation and Lung Expansion (OLE) Therapy in Prolonged Mechanical Ventilated Patients With Atelectasis Evaluated in Multiple Methods
High frequency chest wall oscillation (HFCWO) is currently one of the most common and widespread mechanical airway clearance techniques (ACTs) in clinical practice in China.
- Trial name
- NCT07451405
- Testing
- High frequency chest wall oscillation or other airway clearance therapy, Oscillation and lung expansion
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Non Small Cell Lung Cancer
Exercise Study in Patients With Lung Cancer
In the course of their disease patients with Non small cell lung cancer (NSCLC) often experience impaired psychological and physical functioning resulting in a reduced quality of life (QoL).
- Trial name
- POSITIVE (NCT01581346)
- Testing
- Exercise intervention
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- German Cancer Research Center
Community-acquired Pneumonia, Healthcare-associated Pneumonia
Impact of a Multidimensional Intervention in Elderly Patients With Pneumonia
The hypothesis of this study is that long-term outcome in elderly patients admitted with the diagnosis of community-acquired pneumonia (CAP) or healthcare-associated pneumonia (HCAP) would improve with a multidimensional…
- Trial name
- IMIEPAP (NCT01285869)
- Testing
- Multidimensional intervention
- Where
- Spain
- Volunteers
- 314 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Pulmonary Function
Post-operative Pulmonary Function After Kidney Surgery Under Two Different Techniques
To assess the respiratory and analgesic effects of continuous thoracic paravertebral block versus thoracic epidural in patients undergoing kidney surgery
- Trial name
- NCT03885583
- Testing
- thoracic epidural block, paravertebral block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Chronic Obstructive Pulmonary Disease (COPD)
Reducing Sedentary Behavior in Patients with Severe COPD: a Feasibility Study on Nurse-Led Motivational Intervention
This feasibility study aims to assess the practicality and acceptability of a nurse-led motivational interview intervention designed to reduce sedentary behavior in patients with severe Chronic Obstructive Pulmonary Disease…
- Trial name
- NCT06882863
- Testing
- Motivational interviewing
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Zealand University Hospital
Asthma
Coping Peer Intervention for Adherence
Inner-city African American and Hispanic adolescents suffer from disproportionately high rates of emergency room visits and hospitalizations for acute exacerbations of asthma.
- Trial name
- NCT01169883
- Testing
- Coping Peer Support, Doctor Asthma Messages, Coping Peer Asthma Messages
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Rush University Medical Center
Post COVID-19 Syndrome, Rehabilitation
Implementation of Rehabilitation Program for Post COVID-19
Many people who have suffered from the effects of this disease might now be at risk of long-term impairment and disability. The extent of this impairment and disability is yet unknown, but it is clear from early research that…
- Trial name
- NCT04694768
- Testing
- Rehabilitation
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Job Stress, Workplace Stress
Breath Regulation and Yogic Exercise An Online Therapy for Calm and Happiness During the COVID-19 Pandemic
This study will examine the feasibility of conducting an online Randomized Controlled Trial (RCT) in frontline hospital and long term care healthcare staff in managing COVID-19 patients in London, ON.
- Conditions
- Job Stress, Workplace Stress, Compassion Fatigue, Psychological Trauma
- Trial name
- BREATH (NCT04368676)
- Testing
- Sudarshan Kriya Yoga (SKY), Health Enhancement Program
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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