Clinical trials: Pulmonary Procedures, open to volunteers
Thoracic Surgical Procedures, Postoperative Recovery
Impact of Topical Aromatherapy on Postoperative Quality of Recovery After Lung Resection
The key to early surgery recovery lies in optimal and immediate control of postoperative pain. Despite standard pain management protocols, lung resection is often associated with acute, neuropathic, or chronic pain, compounded by…
- Conditions
- Thoracic Surgical Procedures, Postoperative Recovery, Pain, Complementary Therapies
- Trial name
- AromaQoR (NCT07622602)
- Testing
- topical application of the "AromaQoR" formulation, topical application of sweet almond vegetable oil
- Volunteers
- 124 people
- Sponsor
- University Hospital, Toulouse
Imaging Techniques
Using Xe MRI to Guide Radiation Therapy for Lung Cancer
The purpose of this research study is to explore using MRI scans with xenon to better image lung function, how lung function changes after radiation therapy, and to guide radiation therapy away from parts of the lung that have…
- Trial name
- (XeRTLC) (NCT06925295)
- Testing
- Xenon MRI, Pulmonary Function Testing, Quality of Life Questionnaire
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Sean Fain
Lung Adenocarcinoma, EGFR Activating Mutation
Plasma Exosomes Reveal the Efficacy of Targeted Therapy in Patients With EGFR Mutation in Lung Adenocarcinoma
The objective of this observational study is to explore the therapeutic trajectory of targeted therapy in lung adenocarcinoma patients with epidermal growth factor receptor (EGFR) mutations.
- Trial name
- NCT06730477
- Testing
- observational study
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Long COVID, Post-Acute Sequelae of COVID-19
Mind Body Intervention for Long COVID-19
The goal of this study is to determine if a mind-body intervention can help people suffering from symptoms associated with Long COVID.
- Conditions
- Long COVID, Post-Acute Sequelae of COVID-19, COVID Long-Haul
- Trial name
- NCT06045338
- Testing
- Mind Body Intervention #1
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Beth Israel Deaconess Medical Center
COVID-19 SARS-CoV-2 Infection
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
The purpose of the study is to evaluate whether ibuzatrelvir is effective and safe in adults and adolescents with COVID-19 who do not need to be in the hospital but who are at high risk for progression to severe disease.
- Trial name
- NCT06679140
- Testing
- ibuzatrelvir
- Where
- 256 sites in United States, Argentina and 17 more
- Volunteers
- 2,330 people
- Sponsor
- Pfizer
Lung Cancer (NSCLC)
Exercise and Nutrition on Early-stage NSCLC Outcomes: the STARLighT Study
The general goal of the STARLighT study is to test whether a structured physical exercise and nutritional intervention significantly impacts clinical outcomes in patients with early-stage lung cancer.
- Trial name
- STARLighT (NCT07042724)
- Testing
- Physical exercise and nutrition intervention for the neoadjuvant setting, Physical exercise and nutrition for the adjuvant setting, Health educational material
- Where
- Italy
- Volunteers
- 324 people
- Sponsor
- Universita di Verona
Smoking Cessation, Smoking Behaviors
ACT Lung Health Intervention: Phase Two
This study aims to test a counseling and educational program designed to improve lung health through smoking cessation for Chinese and Korean American smokers at high risk for lung cancer.
- Conditions
- Smoking Cessation, Smoking Behaviors, Smoking, Tobacco, Smoking, Cigarette
- Trial name
- NCT06945120
- Testing
- ACT Lung Health Intervention
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Lung Carcinoma
An Educational Intervention (Lung Toolkit) for Improving Knowledge About Lung Cancer and Screening Among American Indian and Alaskan Native Cigarette Smokers, Lung PATHS Trial
This clinical trial evaluates the acceptability and effectiveness of an educational intervention (Lung Toolkit) for improving knowledge about lung cancer and lung cancer screening among American Indian/Alaskan Native (AI/AN)…
- Trial name
- NCT07615764
- Testing
- Educational Intervention, Interview, Questionnaire Administration
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Chronic Obstructive Pulmonary Disease, Depression
Effectiveness and Cost-effectiveness of Digital Psychological Intervention (EmoEase) in Chinese COPD Patients
Background Mental health issues are common and often overlooked in COPD patients. Digital psychological interventions might help, but their effectiveness in Chinese COPD patients hasn't been studied.
- Conditions
- Chronic Obstructive Pulmonary Disease, Depression, Anxiety
- Trial name
- NCT06026709
- Testing
- EmoEase
- Volunteers
- 1,200 people
- Sponsor
- Peking Union Medical College
Thoracic Surgery
ACBT With Incentive Spirometry Versus High-Frequency Chest Wall Oscillation After Thoracic Surgery
This randomized clinical trial aims to compare the effectiveness of Active Cycle of Breathing Techniques combined with Incentive Spirometry (ACBT + IS) versus High-Frequency Chest Wall Oscillation (HFCWO) in patients undergoing…
- Trial name
- NCT07619716
- Testing
- Active Cycle of Breathing Techniques with Incentive Spirometry, High-Frequency Chest Wall Oscillation
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Pulmonary Embolism
Implementation of a Structured Post-pulmonary Embolism Follow-up Model
Venous thromboembolism (VTE), clinically presenting as deep vein thrombosis or pulmonary embolism (PE) is the third most frequent cardiovascular disease and is associated with substantial short- and long-term morbidity and…
- Trial name
- NCT06037096
- Testing
- Attend-PE model
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Aalborg University Hospital
Fibrotic Interstitial Lung Disease
Artificial Intelligence Enhanced Remote Monitoring in Interstitial Lung Disease
The goal of this clinical trial is to learn whether artificial intelligence AI-enhanced remote monitoring (AIRM) is feasible, safe and acceptable for adults with fibrotic interstitial lung disease (fILD).
- Trial name
- AIRMILD (NCT07844915)
- Testing
- AIRM v1.0 AI-Enhanced Remote Monitoring
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- King's College London
Heart Failure
Liberal or Restricted Fluid Intake in Patients With Heart Failure
Heart failure is the most common cause of admission to hospital and is associated with high morbidity and mortality. Treatment options consist of medical- and device treatment and self-care strategies, where fluid restriction has…
- Trial name
- FLUID-HF (NCT05931614)
- Testing
- Free fluid intake
- Where
- Sweden
- Volunteers
- 326 people
- Sponsor
- Region Stockholm
Heart Surgical Procedure
Blood Velocity Variation in Right Renal and Superior Mesenteric Arteries During Cardio-pulmonary Bypass
The cardiopulmonary by-pass technique, used in cardiac surgery to obtain a bloodless operating field and an immobile heart, determines important effects on the blood vessel wall, especially when a continuous and non-continuous…
- Trial name
- NCT06009809
- Testing
- transesophageal echocardiogram
- Where
- Italy
- Volunteers
- 92 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Obstructive Pulmonary Disease
Tissue Regeneration in Patients With Chronic Obstructive Pulmonary Disease After an Exercise Intervention.
The main objective of this project is to identify mechanisms for lung regeneration in patients with COPD induced by exercise training.
- Trial name
- T-Rex (NCT06335992)
- Testing
- Exercise regime
- Where
- 2 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Uppsala University
Smoking Cessation, Smoking Cessation Counseling Ability and Practice
Evaluating the Impact of CONNECT in a Multilingual Population
This study aims to broaden the reach of the lung cancer screening (LCS) CONNECT program (NCT04149249, NCT06213532), by developing a version of the program to be available to multilingual communities.
- Conditions
- Smoking Cessation, Smoking Cessation Counseling Ability and Practice, Smoking Cessation Counselling, Lung Cancer Screening
- Trial name
- CONNECT-ML (NCT07111936)
- Testing
- CONNECT Intervention for multilingual populations, Saliva Sample, Interview
- Where
- United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Low Back Pain, Chronic
A Combined Exercise Programme Involving Strengthening, Flexibility and Aerobic Exercise for Lower Back Pain
This randomised controlled trial will evaluate the effectiveness of different exercise modalities for individuals with low back pain.
- Trial name
- NCT06921694
- Testing
- Runner group, Swim/Cycle Group
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Non-Tuberculous Mycobacteria Pulmonary Disease, Bronchiectasis
Health Impact of Non-Tuberculous Mycobacteria Pulmonary Disease (NTM-PD)
Nontuberculous mycobacteria (NTM) are environmental organisms found in soil and water. The majority do not cause human disease. When they do, this is mostly as a chronic lung infection in people with long-term lung problems such…
- Trial name
- NCT07192705
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University College, London
Minimally Invasive Surgical Procedures, VATS
Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections
In this study, the reasons for prolonged hospital stay after thoracoscopic (video- or robot-assisted) anatomical lung resections are investigated.
- Conditions
- Minimally Invasive Surgical Procedures, VATS, RATS Surgery, Pulmonary Lobectomy
- Trial name
- PROTRACT (NCT06638645)
- Testing
- VATS/RATS anatomical lung resection
- Where
- 2 sites in Belgium
- Volunteers
- 140 people
- Sponsor
- University Hospital, Ghent
Cystic Fibrosis
Comparative Effects of Mechanical and Manual Airway Clearance Techniques in Cystic Fibrosis
This study will help to establish evidence-based physiotherapy on postural drainage and ACBT against flutter with ACBT is better to improve sleep quality, adherence, dyspnea in patients with cystic fibrosis and which method can…
- Trial name
- NCT07062939
- Testing
- postural drainage with ACBT, flutter with ACBT
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University