Clinical trials: Pulmonary Resection Surgery, active
Thoracotomy, Toracosurgery
Preoperative Nutritional Status and Postoperative Outcomes in Geriatric Lung Resection
Malnutrition is a common comorbidity in patients undergoing thoracic surgery. Furthermore, chronic diseases, polypharmacy, low nutrient intake, reduced appetite, and psychological factors-all frequently observed in geriatric…
- Conditions
- Thoracotomy, Toracosurgery, Thoracic Anesthesia, Older Adults (65 Years and Older)
- Trial name
- NCT07889336
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Pneumococcal Polysaccharide Vaccine, Influenza Vaccines
Preoperative Pneumococcal and Influenza Vaccination to Prevent Postoperative Pulmonary Infection in Patients Undergoing Lung Resection for Pulmonary Nodules or Lung Cancer
Postoperative pneumonia (POP) affects 4%-24% of lung cancer surgery patients, increasing mortality, stay, costs and worsening prognosis, especially in older patients.
- Conditions
- Pneumococcal Polysaccharide Vaccine, Influenza Vaccines, Preoperative, Lung Resection Surgery
- Trial name
- NCT07885540
- Testing
- 23-valent pneumococcal polysaccharide vaccine, Quadrivalent split-virion influenza vaccine
- Volunteers
- 1,278 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Pulmonary Resection Surgery, One Lung Ventillation (OLV)
BMI-Adjusted PEEP During One-Lung Ventilation in Thoracic Surgery
One-lung ventilation (OLV) is required during many thoracic surgical procedures and is associated with reduced functional residual capacity, atelectasis, ventilation-perfusion mismatch, hypoxemia, and potentially…
- Conditions
- Pulmonary Resection Surgery, One Lung Ventillation (OLV), General Anesthetic
- Trial name
- SIMPLE-PEEP (NCT07851740)
- Testing
- Fixed PEEP, BMI-adjusted PEEP
- Where
- 4 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Jesús Manuel Nieves Alonso
Respiratory Monitoring, Thoracic Surgery
AirGo™ Respiratory Monitoring in Lung Resection
Patients undergoing lung resection surgery may experience changes in respiratory function during the perioperative period. Current monitoring methods provide important clinical information but are often limited to specific time…
- Conditions
- Respiratory Monitoring, Thoracic Surgery, Lung Resection Surgery, Respiratory Function
- Trial name
- NCT07838025
- Testing
- AirGoTM system
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection
Pre-incisional Infiltration With Ropivacaine Plus Triamcinolone for Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection, Segmentectomy, Lobectomy of the Lungs
- Trial name
- NCT07603921
- Testing
- Pre-incisional infiltration with ropivacaine plus triamcinolone, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 346 people
- Sponsor
- Beijing Tiantan Hospital
Pulmonary Disease (COPD), Chronic Obstructive, Lung Resection Surgery
Effect of Individualized Positive End-expiratory Pressure (PEEP) in Patients Who Have an Intrinsic PEEP During One-lung Ventilation
This study investigates the effects of three extrinsic PEEP settings-5 cmH2O, 0 cmH2O, and an individualized PEEP (70% of the measured intrinsic PEEP)-on intrinsic PEEP and hemodynamic stability in patients with intrinsic PEEP…
- Trial name
- NCT07638176
- Testing
- PEEP0, PEEP5, PEEPi
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Samsung Medical Center
Postoperative Pain, Chronic Postsurgical Pain
Perioperative Quantitative Sensory Testing and Incision Pain Mapping in Thoracic Surgery
Postoperative pain remains a common and clinically important burden after thoracic surgery and may progress to chronic postsurgical pain.
- Conditions
- Postoperative Pain, Chronic Postsurgical Pain, Thoracic Surgery, Lung Resection
- Trial name
- NCT07653932
- Testing
- Perioperative QST and incision pain mapping assessment
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Tongji Hospital
Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children
Clinical Trial on Safety and Efficacy of Thoracoabdominal Endoscopic Surgical System for Pediatric Surgery
This is a prospective, multi-center, single-arm, target-value clinical trial conducted to evaluate the safety and effectiveness of the Thoracic and Abdominal Endoscopic Surgery System (model WJ-SR01-200) in pediatric surgical…
- Conditions
- Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children, Pyeloplasty, Ureteral Reimplantation
- Trial name
- NCT07530133
- Testing
- Thoracic and Abdominal Endoscopic Surgery System
- Where
- 3 sites in China
- Volunteers
- 64 people
- Sponsor
- Hangzhou Kangji Weijing Medical Robotics Co., Ltd.
Lung Resection Surgery, Anesthesia General
Effect of Oxygen Administration in the Non-dependent Lung on Postoperative Complications After Lung Surgery
The purpose of this study is to analyze the effectiveness of apneic oxygenation and CPAP applied to the non-dependent lung during pulmonary resection surgery in reducing inflammatory response, ischemia-reperfusion injury, and…
- Trial name
- NCT07461779
- Testing
- Medicinal gas - oxygen (Nippon Gases 200 bar), CPAP, Oxygen therapy according to standard clinical practice
- Where
- Spain
- Volunteers
- 177 people
- Sponsor
- Francisco Andres de la Gala
Pulmonary Nodules, Early Stage Lung Cancer (I and II)
Tubeless Strategy for Enhanced Recovery After Sublobar Resection
This is a prospective, randomized controlled clinical trial conducted at a single center. The study aims to evaluate whether a "tubeless" strategy can enhance recovery for patients undergoing minimally invasive thoracoscopic…
- Conditions
- Pulmonary Nodules, Early Stage Lung Cancer (I and II), Thoracoscopic Surgery, Sublobar Resection
- Trial name
- NCT07409129
- Testing
- Laryngeal Mask Airway, Thoracic Paravertebral Block with Local Anesthetic, Non-intubated Anesthesia
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Frailty, Thoracic
Auricular Acupressure in Prehabilitation
Complementary medicine is recognized for its ability to enhance appetite, increase energy, reduce anxiety, decrease pain, and improve sleep, among many other benefits.
- Conditions
- Frailty, Thoracic, Prehabilitation, Lung Surgery
- Trial name
- NCT06516198
- Testing
- Auricular Acupressure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago
Uniportal-VATS, Lung Resection Procedures
Serratus Posterior Superior Intercostal Plane (SPSIP) Block Versus Intercostal Nerve (ICN) Block in Patients Undergoing Uniportal-VATS.
This study aims to assess the effectiveness of the Serratus Posterior Superior Intercostal Plane (SPSIP) block compared to the Intercostal Nerve (ICN) block for postoperative pain control, reduction of opioid analgesic…
- Conditions
- Uniportal-VATS, Lung Resection Procedures, Locoregional Anesthesia, Post-operative Pain Management
- Trial name
- SPUV (NCT07250373)
- Testing
- SPSIP block, ICN block
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
High-risk Lung Resection Surgery
Advanced Goal-Directed Impedancemetry Strategy for Lung Resection Surgery
High-risk patients scheduled for lung resection surgery are increasing and theoretically eligible to perioperative individualized goal-directed fluid therapy (GDFT).
- Trial name
- AEGIS (NCT06156943)
- Testing
- individualized goal-directed fluid therapy by Starling device, group managed by standard of care
- Where
- 10 sites in France
- Volunteers
- 722 people
- Sponsor
- Hospices Civils de Lyon