Clinical trials: Pulmonary Sarcoidosis
Interstitial Lung Disease
Patient-Reported Outcome Study of Project ECHO for ILD
The study will assess whether patients of providers participating in Project ECHO for ILD experience reduced stress, including financial stress, based on their ability to receive timely and local care and services, The study will…
- Trial name
- NCT05450276
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Pulmonary Care and Research Collaborative Limited
Interstitial Lung Diseases, Idiopathic Pulmonary Fibrosis
A Study of the Natural Progression of Interstitial Lung Disease (ILD)
We propose to acquire data and blood samples on all patients being cared for by the Interstitial Lung Disease (ILD) program. Additionally, we will collect data and blood samples from a control group for comparator purposes.
- Conditions
- Interstitial Lung Diseases, Idiopathic Pulmonary Fibrosis, Sarcoidosis, Connective Tissue Disorder
- Trial name
- NCT00470327
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Lung Cancer, Sarcoidosis
Full-Field Optical Coherence Tomography (FFOCT) for Evaluation of Bronchoscopic Small Biopsy Specimens
This study sets out to register imaging of small biopsy specimens obtained during bronchoscopy using full-field optical coherence tomography against standard histologic evaluation.
- Trial name
- NCT05171478
- Testing
- Full-field optical coherence tomography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Sarcoidosis, Pulmonary Rehabilitation
Comparison of the Effects of Yoga and Conventional Physiotherapy Programs in Sarcoidosis
Sarcoidosis is a multisystem disease, characterized by the formation of immune granulomas with various clinical symptoms depending on the involved organs, which can involve many organs and systems associated with emotional and…
- Conditions
- Sarcoidosis, Pulmonary Rehabilitation, Yoga
- Trial name
- NCT06848608
- Testing
- traditional physiotherapy group, yoga program
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Saglik Bilimleri Universitesi
Sarcoidosis, Pulmonary
Peripheral Airway Biopsy in Sarcoidosis
Airway involvement in sarcoidosis was demonstrated in a meaningful, albeit variable, proportion of patients through biopsy of the central, endoscopically visible airways.
- Trial name
- Sopranos (NCT05759221)
- Testing
- Bronchoscopy with airway biopsy
- Where
- Italy
- Volunteers
- 79 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sarcoidosis, Pulmonary
Risk Indicators of Sarcoidosis Evolution-Unified Protocol
The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit.
- Trial name
- RISE-UP (NCT05567133)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of California, San Francisco
Pulmonary Sarcoidosis
Comparison of Different Exercise Training on Exercise Capacity and Fatigue in Patients With Sarcoidosis
Pulmonary rehabilitation is a key element in the management of people with chronic respiratory disease. A properly followed supervised physical training program in sarcoidosis is safe and has no absolute contraindications.
- Trial name
- NCT05368883
- Testing
- Exercise- One-Legged, Exercise-Two-Legged
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Istanbul University - Cerrahpasa
Pulmonary Sarcoidosis
Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Patients With Pulmonary Sarcoidosis
The purpose of this study is to assess if ACZ885 will improve lung function in association with reduction of tissue inflammation in patients with chronic sarcoidosis.
- Trial name
- NCT02888080
- Testing
- ACZ885
- Where
- 8 sites in United States, Germany and 1 more
- Volunteers
- 40 people
- Sponsor
- Novartis Pharmaceuticals
Sarcoidosis
Riociguat for Sarcoidosis Associated Pulmonary Hypertension
Double blind placebo controlled trial of riociguat for sarcoidosis associated pulmonary hypertension
- Trial name
- RioSAPH (NCT02625558)
- Testing
- Riociguat
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Lung Cancer,, Mediastinal Tumors,
Virtual Bronchoscopy (VB) vs. Endobronchial Ultrasound (EBUS) Guided Mediastinal Sampling
The study has been designed to evaluate the clinical application of the new virtual bronchoscopy (VB) -based system for transbronchial sampling of the mediastinal masses or enlarged lymph nodes.
- Conditions
- Lung Cancer,, Mediastinal Tumors,, Lymphomas,, Sarcoidosis,
- Trial name
- VB/EBUS-TBNA (NCT01784185)
- Testing
- virtual bronchoscopy guided transbronchial needle aspiration, endobronchial ultrasound guided transbronchial needle aspiration
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Warsaw
Pulmonary Sarcoidosis
Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis
This randomized, double-blind, placebo matched to efzofitimod-controlled, study will evaluate the safety, tolerability, immunogenicity, pharmacokinetic (PK), and preliminary efficacy of multiple ascending doses of IV efzofitimod…
- Trial name
- NCT03824392
- Where
- 15 sites in United States
- Volunteers
- 37 people
- Sponsor
- aTyr Pharma, Inc.
Interstitial Lung Diseases
Individual Sensitivity for Interstitial Lung Diseases
Interstitial lung diseases (ILD) is a collective noun for various chronic lung diseases, including sarcoidosis and idiopathic lung fibrosis (IPF).
- Trial name
- NCT00741572
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Maastricht University Medical Center
Interstitial Lung Disease
Gabapentin vs. Benzonatate vs. Standard of Care for Cough in ILD
Absence of a clear standard of care and approved drug for chronic cough, the commonest symptom in ILD, calls for further research in this area.
- Trial name
- GAZEBO-ILD (NCT07859839)
- Testing
- Gabapentin, Benzonatate 200 mg, Standard of care treatment for ILD
- Where
- India
- Volunteers
- 177 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Sarcoidosis
Registry for Advanced Sarcodiosis
Registry with evaluation and genetic information of patients with advanced sarcoidosis and matched sarcoidosis
- Trial name
- REAS (NCT03769987)
- Testing
- observation
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Cincinnati
Sarcoidosis-associated Pulmonary Hypertension
A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag
Oral selexipag is commercially available in several countries for the treatment of a particular group of pulmonary hypertension (PH) called pulmonary arterial hypertension (PAH).
- Trial name
- SPHINX (NCT03942211)
- Testing
- Selexipag
- Where
- 38 sites in United States, Belgium and 8 more
- Volunteers
- 10 people
- Sponsor
- Actelion
SARCOIDOSIS
Sarcoidosis-associated Pulmonary Hypertension
This prospective study was conducted to explore clinical characteristics and outcomes of patients diagnosed with pulmonary sarcoidosis and PH. The investigators also assessed the role of D -dimer levels in these population.
- Trial name
- NCT01139710
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Meir Medical Center
Sarcoidosis, Pulmonary, Telerehabilitation
Feasibility & Effect of a Tele-rehabilitation Program in Pulmonary Sarcoidosis Pulmonary Sarcoidosis
Pulmonary sarcoidosis (PS) is defined as a multisystem granulomatous disorder of unknown cause affecting different vital organs, especially the lungs. PS manifest in reduction of pulmonary function.
- Trial name
- TeleSarco (NCT03914027)
- Testing
- Telerehabilitation
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Aarhus University Hospital
Interstitial Lung Disease, Sarcoidosis
Multi-elemental Imaging of Lung Tissues With LIBS (Laser-induced Breakdown Spectroscopy)
Evaluate the feasibility of performing a multi-elemental imaging analysis of lung specimens from patients with ILDs, with an technology named LIBS (Laser Induced-Breakdown Spectroscopy)
- Conditions
- Interstitial Lung Disease, Sarcoidosis, Idiopathic Pulmonary Fibrosis
- Trial name
- MEDICO-LIBS (NCT03901196)
- Testing
- Elemental analysis
- Where
- 4 sites in France
- Volunteers
- 86 people
- Sponsor
- University Hospital, Grenoble
Lymphadenopathy, Lung Cancer
EBUS-TBNA vs Flex 19G EBUS-TBNA
Endobronchial ultrasound (EBUS) guided transbronchial needle aspiration (EBUS-TBNA) is an excellent tool for sampling enlarged mediastinal and hilar lymph nodes, but only provides needle aspirate samples which are often adequate…
- Conditions
- Lymphadenopathy, Lung Cancer, Sarcoidosis, Lymphoma
- Trial name
- NCT02592837
- Testing
- Flexible 19G EBUS-TBNA needle, 21G EBUS-TBNA needle
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Lung Disease, Chronic Obstructive, Lung Disease, Interstitial
Diagnosis of Cardio-Pulmonary Pathology Using Transthoracic Parametric Doppler (TPD)
This is a study that seeks to characterize data obtained from patients with a variety of lung diseases using ultrasound signals obtained from the lung tissue.
- Conditions
- Lung Disease, Chronic Obstructive, Lung Disease, Interstitial, Asthma, Sarcoidosis
- Trial name
- NCT01361139
- Where
- 2 sites in Israel
- Volunteers
- 500 people
- Sponsor
- Echosense Ltd.