Clinical trials: Pulmonary Sarcoidosis
Thyroid Pathology, Head and Neck Cancer (H&N)
FAPI PET Imaging - An Exploratory Study
This study is testing a new imaging tracer called [18F]FAPI-74 with PET scans. Researchers want to find out how well this tracer shows certain diseases in the body, including several types of cancer and some non-cancer conditions…
- Conditions
- Thyroid Pathology, Head and Neck Cancer (H&N), Sinonasal Tract Tumor, Sarcoidosis
- Trial name
- FAPIPET (NCT07705074)
- Testing
- [18F]FAPI-74 PET/CT
- Where
- 5 sites in Switzerland
- Volunteers
- 770 people
- Sponsor
- Martin Huellner
SARCOIDOSIS
Sarcoidosis-associated Pulmonary Hypertension
This prospective study was conducted to explore clinical characteristics and outcomes of patients diagnosed with pulmonary sarcoidosis and PH. The investigators also assessed the role of D -dimer levels in these population.
- Trial name
- NCT01139710
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Meir Medical Center
Interstitial Lung Disease
Patient-Reported Outcome Study of Project ECHO for ILD
The study will assess whether patients of providers participating in Project ECHO for ILD experience reduced stress, including financial stress, based on their ability to receive timely and local care and services, The study will…
- Trial name
- NCT05450276
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Pulmonary Care and Research Collaborative Limited
Sarcoidosis
A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis
This study tests the safety and effectiveness of ustekinumab or golimumab compared to placebo (placebo looks like the drugs being studied, but has no active ingredients).
- Trial name
- NCT00955279
- Testing
- Golimumab, Ustekinumab
- Where
- 53 sites in United States, Belgium and 7 more
- Volunteers
- 173 people
- Sponsor
- Centocor, Inc.
Sarcoidosis
Low-dose Dexamethasone in Newly Diagnosed Pulmonary Sarcoidosis
This trial examines whether low grade suppression of the initial inflammatory process of sarcoidosis by intervention with low-dose dexamethasone therapy achieves significant alleviation of (sub-)acute symptoms, improvement in…
- Trial name
- DEXSAR (NCT01920919)
- Testing
- Dexamethasone
- Where
- Netherlands
- Volunteers
- 76 people
- Sponsor
- St. Antonius Hospital
Mediastinal Lymphadenopathy, Sarcoidosis, Pulmonary
Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy
The investigators will compare endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) with intranodal forceps biopsy (EBUS-IFB) as it relates to the rate of diagnosis of suspected sarcoidosis.
- Conditions
- Mediastinal Lymphadenopathy, Sarcoidosis, Pulmonary, Mediastinal Diseases
- Trial name
- NCT05374447
- Testing
- Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- George Washington University
Cervical Cancer, Fallopian Tube Cancer
Immunotoxin Therapy in Treating Patients With Advanced Cancer
RATIONALE: Immunotoxins can locate tumor cells and kill them without harming normal cells. Immunotoxin therapy may be an effective treatment for advanced cancer.
- Conditions
- Cervical Cancer, Fallopian Tube Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00006981
- Testing
- SS1(dsFv)-PE38 immunotoxin
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Pulmonary Sarcoidosis
Randomized Controlled Trial of Hydroxychloroquine Combined With Low-dose Corticosteroid in Pulmonary Sarcoidosis
"The reference treatment for pulmonary sarcoidosis is prolonged systemic corticosteroid therapy, which improves dyspnea, fatigue and respiratory function.
- Trial name
- QUIDOSE (NCT05247554)
- Testing
- Hydroxychloroquine + low-dose prednisone, Prednisone
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sarcoidosis
Prednisolone for 12 Versus 6 Months to Treat Pulmonary Sarcoidosis
In this study, the efficacy and safety of treating pulmonary sarcoidosis with 12 months vs. 6 months of prednisolone will be compared.
- Trial name
- DURASARC (NCT06654934)
- Testing
- Prednisolone
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Sarcoidosis, Pulmonary Rehabilitation
Comparison of the Effects of Yoga and Conventional Physiotherapy Programs in Sarcoidosis
Sarcoidosis is a multisystem disease, characterized by the formation of immune granulomas with various clinical symptoms depending on the involved organs, which can involve many organs and systems associated with emotional and…
- Conditions
- Sarcoidosis, Pulmonary Rehabilitation, Yoga
- Trial name
- NCT06848608
- Testing
- traditional physiotherapy group, yoga program
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Saglik Bilimleri Universitesi
Lung Cancer, Sarcoidosis
Rapid On-site Cytopathologic Evaluation in the Diagnosis of Hilar/Mediastinal Adenopathy
The purpose of this study is to determine whether rapid on-site cytopathologic evaluation (ROSE) can increase the diagnostic yield of transbronchial needle aspiration (TBNA) in the diagnosis of hilar and mediastinal…
- Conditions
- Lung Cancer, Sarcoidosis, Tuberculosis
- Trial name
- NCT00915330
- Testing
- Rapid on-site cytopathologic evaluation (ROSE), TBNA
- Where
- Italy
- Volunteers
- 164 people
- Sponsor
- Maggiore Bellaria Hospital, Bologna
Isolated Mediastinal Lymphadenopathy, Sarcoidosis
A Clinical tRial of Endobronchial Ultrasound for the Diagnosis of MEDiastinal lymphadenopathY (REMEDY)
Enlarged glands in the chest (mediastinal lymphadenopathy) is a common problem and may have a variety of different causes. In the past an operation (mediastinoscopy) was required to diagnose the glands.
- Conditions
- Isolated Mediastinal Lymphadenopathy, Sarcoidosis, Tuberculosis, Lung Cancer
- Trial name
- REMEDY (NCT00932854)
- Testing
- EBUS
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- University College London Hospitals
Cervical Cancer, Fallopian Tube Cancer
Immunotoxin Therapy in Treating Patients With Advanced Solid Tumors
RATIONALE: Immunotoxins can locate tumor cells and kill them without harming normal cells. Immunotoxin therapy may be effective in treating advanced solid tumors.
- Conditions
- Cervical Cancer, Fallopian Tube Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00066651
- Testing
- SS1(dsFv)-PE38 immunotoxin
- Where
- 2 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Emphysema, Chronic Obstructive Pulmonary Disease (COPD)
Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability
The purpose of this research study is to perfect the technique of EVLP and learn about the safety of transplanting lungs that have been ventilated (attached to a breathing machine or ventilator to deliver oxygen) and perfused…
- Conditions
- Emphysema, Chronic Obstructive Pulmonary Disease (COPD), Cystic Fibrosis, Pulmonary Fibrosis
- Trial name
- NCT01241942
- Testing
- Steen Solution™, Conventional Lung Transplant
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of North Carolina, Chapel Hill
Interstitial Lung Diseases, Sarcoidosis
The Occurence of Inflammation and Oxidative Stress in Lung Diseases
Reactive oxygen species (ROS) are suggested to play a pivotal role in ILD. Little is known, however, about the endogenous antioxidant levels in ILD that can offer protection against ROS.
- Conditions
- Interstitial Lung Diseases, Sarcoidosis, Idiopathic Pulmonary Fibrosis, COPD
- Trial name
- NCT00512967
- Where
- Netherlands
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcoidosis, Precapillary Pulmonary Hypertension
Inhaled Treprostinil in Sarcoidosis Patients With Pulmonary Hypertension
This study aims to evaluate the efficacy and safety of inhaled treprostinil in subjects with sarcoidosis-associated interstitial lung disease and pulmonary hypertension.
- Conditions
- Sarcoidosis, Precapillary Pulmonary Hypertension, Interstitial Lung Disease
- Trial name
- SAPPHIRE (NCT03814317)
- Testing
- Inhaled Treprostinil
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Florida
Sarcoidosis; Antimycobacterial Therapy
Phase II Investigation of Antimycobacterial Therapy on Progressive, Pulmonary Sarcoidosis
The primary purpose of this study is to investigate the efficacy and safety of oral antimycobacterial therapy in patients with confirmed progressive pulmonary sarcoidosis.
- Trial name
- NCT02024555
- Testing
- Levofloxacin, Ethambutol, Azithromycin
- Where
- 6 sites in United States
- Volunteers
- 97 people
- Sponsor
- Vanderbilt University
Lung Cancer, Tuberculosis
A Trial on Clinical Efficacy of 1% Versus 2% Lignocaine in Cough Suppression and Pain Relief in Patients Undergoing Flexible Bronchoscopy
Flexible bronchoscopy is a common procedure performed by pulmonary physicians. The use of topical anesthesia, analgesia, and sedation during flexible bronchoscopy varies among physicians, institutions and geographic locations…
- Conditions
- Lung Cancer, Tuberculosis, Sarcoidosis, Interstitial Lung Disease
- Trial name
- NCT01955824
- Testing
- 1% lignocaine, 2% lignocaine
- Where
- India
- Volunteers
- 500 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Sarcoidosis, Pulmonary
An RCT of NBI vs. White Light Guided Endobronchial Biopsy in Suspected Sarcoidosis
In the diagnosis of patients with sarcoidosis, there is paucity of literature on the diagnostic yield of the endobronchial biopsies obtained with narrow band imaging (NBI) bronchoscopy.
- Trial name
- NABS (NCT05311150)
- Testing
- Narrow band imaging bronchoscopy guided endobronchial biopsy, White light bronchscopy guided endobronchial biopsy
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pulmonary Sarcoidosis
The Effect of Inspiratory Muscle Training and Breathing Exercises Combined With Upper Extremity and Trunk in Patients With Sarcoidosis
This is an educational work. Thirty patients with pulmonary sarcoidosis will be included in the study and randomly selected into two training groups.One group will receive home inspiratory muscle training (IMT) for 15 minutes…
- Trial name
- physio (NCT04173689)
- Testing
- Threshold IMT, breathing exercises combined with upper extremity and trunk
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul University - Cerrahpasa