Clinical trials: Pulmonary Vascular Resistance Abnormality, active
Heart Failure, Pulmonary Hypertension
Mechanisms of Pulmonary Vascular Dysfunction in Heart Failure
Heart failure (HF) patients often develop pulmonary hypertension (PH) that leads to transition into a biventricular HF with poor prognosis.
- Conditions
- Heart Failure, Pulmonary Hypertension, Pulmonary Vascular Resistance Abnormality
- Trial name
- LUNG-HF (NCT06331208)
- Testing
- non-contrast chest CT, spirometry with diffusing lung capacity for carbon monoxide (DLCO) analysis, Omics analysis of blood plasma obtained from pulmonary artery or peripheral blood
- Where
- Czechia
- Volunteers
- 230 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Single-ventricle, Pulmonary Vascular Resistance Abnormality
ET1 Concentration, Metabolic Pathway Activation, and Pulmonary Blood Flow in Infants Undergoing Superior Cavo-Pulmonary Anastomosis
This is a novel preliminary study of biomarkers of pathologic pre-operative pulmonary vascular development, elevated pre-operative Pulmonary Vascular Resistance Index (PVRi), and complications associated with decreased…
- Conditions
- Single-ventricle, Pulmonary Vascular Resistance Abnormality, Superior Cavo-Pulmonary Anastomosis, Endothelin
- Trial name
- NCT03404258
- Testing
- Research Blood Sampling
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver