Clinical trials: Pulpitis
Pulpitis - Irreversible
Comparative Evaluation of Partial and Complete Pulpotomy in Permanent Molars
This study will compare the outcome of partial pulpotomy and complete pulpotomy in mature permanent molars with clinical signs indicative of irreversible pulpitis
- Trial name
- NCT04397315
- Testing
- Pulpotomy to the level of canal orifices, Pulpotomy up to superficial 2-3 mm of pulp chamber
- Where
- India
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pulpitis, Pulp Exposure, Dental
Pulpotomy in Carious Permanent Mature Teeth: Pulp Survival and Risk Factors
This Trial evaluated the extent of pulp survival following pulpotomy in the permanent tooth pulp exposed by caries and identify potential risk factors for pulpal complications.
- Conditions
- Pulpitis, Pulp Exposure, Dental, Pulp and Periapical Tissue Disease
- Trial name
- NCT03490422
- Testing
- Pulpotomy
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Symptomatic Irreversible Pulpitis (SIP)
Intraoral Cryotherapy on Anesthetic Efficacy in Mandibular Incisors
The aim is to compare the contributions of intraoral cryotherapy and supplemental lingual infiltration anesthesia to buccal infiltration anesthesia in mandibular incisor teeth with irreversible pulpitis in terms of anesthetic…
- Trial name
- NCT07517367
- Testing
- Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Ondokuz Mayıs University
Pulpitis
Assessment of Postoperative Pain After Using Reciproc Versus One Shape NiTi Systems
The aim of this study is to assess the postoperative pain and the intake of analgesic medication after using Reciproc single-file reciprocating system or One Shape single-file continuous rotary system in patients with symptomatic…
- Trial name
- NCT02940704
- Testing
- Reciproc, One Shape
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Effect of Menstrual Phase on the Anesthetic Efficacy
The goal of this observational prospective clinical study is to learn whether the menstrual phase influences the anesthetic efficacy of inferior alveolar nerve block (IANB) in female patients aged 20-40 years with symptomatic…
- Trial name
- NCT07306533
- Testing
- Inferior Alveolar Nerve Block
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Jamia Millia Islamia
Irreversible Pulpitis, Root Canal Treatment
Simultaneous Working Length Detection Methods
Precise knowledge of the apical construction, which determines the end of the area for canal preparation and filling, is essential for the success of root canal treatment and the management of postoperative pain.
- Trial name
- NCT06507982
- Testing
- EWL, SWL, RWL
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Reversible Pulpitis, Extremely Deep Caries
Outcome of Direct Pulp Capping and Partial Pulpotomy in Reversible Pulpitis
AIM: -The aim of the study is to compare the outcome of Direct Pulp Capping and Partial Pulpotomy in mature permanent teeth with Reversible Pulpitis OBJECTIVES: - Primary Objective: to compare the difference in clinical and…
- Trial name
- NCT07300124
- Testing
- Partial Pulpotomy in Reversible Pulpitis, Direct pulp capping with MTA
- Where
- India
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Mandibular Nerve, Mandibular Nerve Blocks
Comparative Assessment of Mental/Incisive and Inferior Alveolar Nerve Block Anesthesia in Root Canal Treatment of Mandibular Premolars
The goal of this clinical trial is to systematically compare the pain scores and anesthesia efficacy of IANB and MNB in the treatment of symptomatic mandibular first and second premolars.
- Conditions
- Mandibular Nerve, Mandibular Nerve Blocks, Premolars, Mental Nerve Block
- Trial name
- NCT06679660
- Testing
- inferior alveolar nerve block with 4% articaine, Mental/Incisive Nerve Block (%4 Articaine)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Regenerative Pulpotomy for Symptomatic Pulpitis of Mandibular Permanent Molars With Mature Apices
Clinical and Radiographic Success Following Regenerative Pulpotomy Using Chitosan Hydrogel Versus Platelet Rich Fibrin in Mature Mandibular Molars
The aim of this study is to assess the clinical and radiographic success and postoperative pain in mature mandibular molars following vital pulp therapy using chitosan hydrogel versus platelet rich fibrin.
- Trial name
- NCT06828978
- Testing
- Full Pulpotomy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible, Vitamin D Deficiency
Effect of Vitamin D on Postoperative Pain in Symptomatic Irreversible Pulpitis
Vitamin D deficiency (VDD) is a prevalent global health concern that has been linked to altered pain perception through its effects on inflammatory pathways, nociceptor activity, and neurotrophic signaling.
- Trial name
- NCT07579637
- Testing
- Vitamin D3
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Future University in Egypt
Symptomatic Irreversible Pulpitis
Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression
To assess the effect of using diclofenac potassium versus prednisolone as a pre-medication compared to placebo on: Intensity of post-endodontic pain in patients with symptomatic irreversible pulpitis. Pulpal IL-8 expression.
- Trial name
- NCT04608981
- Testing
- Prednisolone 30 mg, Diclofenac Potassium 50mg Tab
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis
Effect of Preoperative Oral Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Block With Supplemental Buccal and Lingual Infiltrations Using Articaine in Mandibular Molar Teeth With Irreversible Pulpitis
Effect of preoperative oral Ibuprofen on anesthetic efficacy of inferior alveolar nerve block with supplemental buccal and lingual infiltrations using articaine in mandibular molar teeth with irreversible pulpitis.
- Trial name
- NCT05927922
- Testing
- Oral Ibuprofen (Abbott, Egypt)
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
Clinical and Radiographic Evaluation of Calcium Hypochlorite Versus Saline As Root Canal Irrigants in Pulpectomy of Primary Molars: a Randomized Clinical Trial
The aim of this study is to evaluate the clinical and radiographic success of Calcium Hypochlorite versus Saline as root canal irrigants in pulpectomy of primary molars.
- Trial name
- NCT06748781
- Testing
- Pulpectomy using 2.5% Calcium Hypochlorite root canal irrigant., Pulpectomy using Saline as root canal irrigant
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Root Canal Infection
Success Rate of 4 Injection Protocols for Mandibular First Molars With Symptomatic Irreversible Pulpitis
Achieving profound anesthesia during endodontic treatment of mandibular molars with symptomatic irreversible pulpitis is still a demanding clinical challenge.
- Trial name
- NCT04929522
- Testing
- local anesthesia
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Symptomatic Irreversible Pulpitis
Comparison Between M-Pro and ProTaper Next
Comparing the postoperative pain resulting after mechanical instrumentation using M-pro files versus that resulting after using ProTaper Next rotary files in lower molar with symptomatic Irreversible pulpitis molars.
- Trial name
- NCT03692039
- Testing
- M-pro files in rotating motion, ProTaper Next files in rotating motion
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpectomy, Primary Teeth Indicated for Pulp Therapy
Comparative Evaluation of Pediatric Rotary Files and Hand Files in Primary Molars
The goal of this clinical trial is to evaluate and compare the efficacy of Kedo-Nano Plus rotary files, Kedo-S Square rotary files, and manual K-files for biomechanical preparation during pulpectomy of primary mandibular molars…
- Conditions
- Pulpectomy, Primary Teeth Indicated for Pulp Therapy, Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis
- Trial name
- NCT07702877
- Testing
- Pulpectomy, Kedo-S Square rotary file, Manual K files
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Goa Dental College
Moderate Pulpitis
COMPARATIVE EVALUATION OF DIRECT PULP CAPPING AND COMPLETE PULPOTOMY IN MATURE PERMANENT MANDIBULAR MOLARS WITH CLINICAL SIGNS INDICATIVE OF MODERATE PULPITIS
Title: Comparative evaluation of direct pulp capping and complete pulpotomy in mature permanent mandibular molars with clinical signs indicative of moderate pulpitis: Randomized Clinical Trial Rationale: According to new Wolters…
- Trial name
- NCT06447753
- Testing
- Direct pulp capping, Complete Pulpotomy
- Where
- India
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Irreversible Pulpitis
Salvadora Persica-Zinc Oxide Versus MTA as Pulpotomy Agents in Mature Permanent Molars With Irreversible Pulpitis
Pulpotomy has emerged as a conservative treatment option for mature permanent teeth with irreversible pulpitis, aiming to preserve pulp vitality while avoiding the limitations of conventional root canal treatment.
- Trial name
- NCT07630181
- Testing
- Mineral Trioxide Aggregate, Salvadora persica Extract + Zinc Oxide
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Postgraduate Medical Institute, Lahore
Dental Caries, Teeth Loss
The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth
Dentists commonly use bitewing radiographs (dental X-rays) together with a visual-tactile (clinical) examination to detect cavities between the back teeth.
- Conditions
- Dental Caries, Teeth Loss, Necrosis of Pulp, Irreversible Pulpitis
- Trial name
- BROCC (NCT07882693)
- Testing
- Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jukka Leinonen
Effect of Drug
Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain
This study aims to compare the pain reduction efficacy of Trypsin-Chymotrypsin and Naproxen sodium after root canal treatment in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT06562816
- Testing
- Trypsin-Chymotrypsin, Naproxen Sodium 550mg
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences