Clinical trials: Pulpitis
Irreversible Pulpitis
Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis
This study evaluates the effect of two flushing agents (epigallocatechin gallate (EGCG) and sodium hypochlorite (NaOCl)) during full pulpotomy using two different calcium silicate-based materials (MTA and premixed bioceramic…
- Trial name
- NCT05811403
- Testing
- Epigallocatechin gallate (EGCG), Sodium hypochlorite (NaOCl), Mineral trioxide aggregate (MTA)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Preoperative Dexamethasone Injection to Improve Local Anesthesia Success in Endodontic Treatment
This study aims to determine whether giving a single dose of 4mg dexamethasone before root canal treatment can reduce the amount of pain patients experience during the procedure .
- Trial name
- DILAS (NCT07699315)
- Testing
- dexamethasone, Saline (0.9% NaCl)
- Volunteers
- 60 people
- Sponsor
- Watim Medical & Dental College
Irreversible Pulpitis
Clinical and Radiographic Outcomes of Pulpotomy Versus Pulpectomy in Primary Molars With Symptomatic Irreversible Pulpitis
The goal of this clinical trial is to learn if MTA pulpotomy compared to pulpectomy have the same clinical and radiographic success in treatment of primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT07783217
- Testing
- MTA pulp dressing material, Metapex
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Minia University
Endodontic Inflammation
Evaluation of the Effect of Different Irrigation Activation Methods During Endodontic Retreatment
The persistent and secondary intraradicular infections are the primary causes of post-treatment disease following endodontic treatment of any tooth.
- Trial name
- NCT07779148
- Testing
- Xp Finisher R file
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Minia University
Molar-Incisor Hypomineralization (MIH)
Total Pulpotomy With Two Repair Cements in Hypomineralized Teeth
BRIEF SUMMARY The goal of this clinical trial is to learn whether two materials used during pulpotomy treatment can reduce pain after treatment in children with molar-incisor hypomineralization (MIH), deep tooth decay, and…
- Trial name
- DOR-PULP (NCT07774806)
- Testing
- MTA group, CIMMO DTA® group
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Meire Coelho Ferreira
Symptomatic Irreversible Pulpitis (SIP)
Comparison Of Acetaminophen, NSAIDs, And Trypsin-Chymotrypsin Plus Acetaminophen For Post-Endodontic Pain After Single-Visit Root Canal Treatment
This randomized control trial will be planned according to PRIRATE 2020 guideline for reporting randomized trials in Endodontics.
- Trial name
- NCT07759349
- Testing
- Acetaminophen, NSAID, trypsin-chymotrypsin
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Vital Pulp Therapies, Pulpotomy
Comparison of Sodium Hypochlorite Gel and Solution With and Without Nanoparticles for Postoperative Pain After Pulpotomy in Permanent Mandibular Molars
This randomized clinical trial aims to compare the effect of 2% sodium hypochlorite gel and solution, with and without chitosan nanoparticles, on postoperative pain following pulpotomy in mature permanent mandibular molars with…
- Conditions
- Vital Pulp Therapies, Pulpotomy, Irriversible Pulpitis, Postoperative Pain
- Trial name
- NaOCl Pulpotom (NCT07774130)
- Testing
- Sodium Hypochlorite gel 2%, Sodium hypochlorite gel 2% with chitosan nano particles, Sodium hypochlorite solution 2% with chitosan nanoparticles
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Irreversible Pulpitis With Apical Periodontitis
Full Pulpotomy in Permanent Teeth With Irreversible Pulpitis and Apical Periodontitis
This study will evaluate whether full pulpotomy can successfully treat mature permanent teeth with irreversible pulp inflammation and a periapical lesion.
- Trial name
- NCT07768852
- Testing
- Full pulpotomy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Irreversible Pulpitis
Pulpotomy in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis
This is a clinical trial to assess the treatment outcomes of pulpotomy in vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06149845
- Testing
- Full Pulpotomy
- Where
- 2 sites in Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Qatar University
Irreversible Pulpitis
Treatment Outcomes of Pulpotomy vs. Pulpectomy in Vital Primary Molars With Symptomatic Irreversible Pulpitis
This randomised controlled trial aims to compare treatment outcomes between pulpotomy and pulpectomy when used to treat vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06183203
- Testing
- Pulpotomy, Pulpectomy
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nebu Philip
Irreversible Pulpitis
Treatment Outcomes of Pulpotomy Versus Pulpectomy in Vital Primary Molars Diagnosed With Irreversible Pulpitis
This randomised controlled trial aims to compare treatment outcomes between pulpotomy and pulpectomy when used to treat vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06904781
- Testing
- Pulpotomy, Pulpectomy
- Where
- 2 sites in Jordan, Qatar
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Qatar University
Irreversible Pulpitis (Toothache)
Laser Assisted Pulpotomy Versus MTA Pulpotomy in Permanent Teeth With Irreversible Pulpitis
This study compares two methods used during full pulpotomy, a treatment for teeth with deep tooth decay that has exposed the dental pulp.
- Trial name
- NCT07761962
- Testing
- Diode laser full pulpotomy, Sodium hypochlorite pulpotomy
- Where
- Jordan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Deep Caries
Direct Pulp Capping Compared to Partial Pulpotomy in Carious Pulp Exposures
This a prospective randomized clinical trial that compare vital pulp therapy procedures in permanent teeth with carious pulp exposure.
- Trial name
- Pulp cap (NCT06495242)
- Testing
- Direct pulp capping and partial pulpotomy
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Irreversible Pulpitis
Clinical and Radiographic Evaluation of Propolis as a Hemostatic Agent in Full Pulpotomy of Mature Permanent Molars With Irreversible Pulpitis
The goal of this randomized clinical trial is to assess the effectiveness of propolis as a hemostatic agent in full pulpotomy for mature permanent molars with irreversible pulpitis, compared to sodium hypochlorite (NaOCl).
- Trial name
- NCT06679075
- Testing
- Full pulpotomy using propolis and bioceramic putty, Full pulpotomy using Propolis and MTA, Full pulpotomy using sodium hypochlorite and bioceramic putty
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Misr International University
Pulpitis in Permanent Teeth, Dental Caries Extending to Pulp
Pulp Inflammatory Markers and Outcome of Pulpotomy
This is a prospective clinical study that aims to investigate the level of inflammatory mediators in the inflamed dental pulp and its potential relationship to the outcome of full pulpotomy in mature permanent teeth with carious…
- Trial name
- pulpitis (NCT06960603)
- Testing
- Full pulpotomy
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pain, Postoperative Pain
Efficacy of Different Drugs to Control Post Root Canal Treatment Pain
Root canal therapy will ideally eliminate post-endodontic pain but occasionally analgesics are needed to diminish the pain [Owatz et al 2007].
- Conditions
- Pain, Postoperative Pain, Irreversible Pulpitis
- Trial name
- NSAID (NCT02417337)
- Testing
- Paracetamol, Ibuprofen, Mefenamic Acid
- Where
- Sudan
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Khartoum
Symptomatic Irreversible Pulpitis (SIP)
Effect of Preoperative Diclofenac Potassium Dose on Endodontic Pain
The aim of this study is to assess the effect of different doses of diclofenac potassium premedication (100mg vs 50mg) on anesthetic success of 4% articaine buccal infiltration and post-operative pain as compared to placebo in…
- Trial name
- NCT07743372
- Testing
- Diclofenac potassium 100mg, Diclofenac potassium 50mg
- Volunteers
- 90 people
- Sponsor
- Cairo University
Reversible Pulpitis, Irreversible Pulpitis
Biomarkers for Differentiating Reversible and Irreversible Pulpitis
This observational study aims to evaluate the role of inflammatory, oxidative stress, neurogenic, and immunological biomarkers obtained from pulpal blood in the differential diagnosis of normal pulp, reversible pulpitis, and…
- Conditions
- Reversible Pulpitis, Irreversible Pulpitis, Healthy Pulp
- Trial name
- PULPBIOM (NCT07658742)
- Testing
- Pulpal Blood Biomarker Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Safa
Reversible Pulpitis, Deep Caries
Comparative Evaluation of Direct Pulp Capping Between Deep and Extremely Deep Caries in Mature Permanent Mandibular Molars .
The aim of the study is to compare the clinical and radiographic outcomes of direct pulp capping for deep and extremely deep caries in mature permanent mandibular molars with reversible pulpitis.
- Conditions
- Reversible Pulpitis, Deep Caries, Extremely Deep Caries
- Trial name
- NCT07696702
- Testing
- Direct pulp capping in extremely deep carious lesion., Direct pulp capping in deep carious lesion.
- Where
- India
- Volunteers
- 130 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak